654 research outputs found
Does the use of nest materials in a ground-nesting bird result from a compromise between the risk of egg overheating and camouflage?
Many studies addressing the use of nest materials by animals have
focused on only one factor to explain its function. However, the
consideration of more than one factor could explain the apparently
maladaptive choice of nest materials that make nests conspicuous to
predators. We experimentally tested whether there is a trade-off in the
use of nest materials between the risks of egg predation versus
protection from overheating. We studied the ground-nesting Kentish
plover, Charadrius alexandrinus, in southern Spain. We added
materials differing in thermal properties and coloration to the nests,
thus affecting rates of egg heating, nest temperature and camouflage.
Before these manipulations, adults selected materials that were lighter
than the microhabitat, probably to buffer the risk of egg overheating.
However, the adults did not keep the lightest experimental materials,
probably because they reduced camouflage, and this could make the
nests even more easily detectable to predators. In all nests, adults
removed most of the experimental materials independently of their
properties, so that egg camouflage returned to the original situation
within a week of the experimental treatments. Although the thermal
environment may affect the choice of nest materials by plovers,
ambient temperatureswere not so high at our study site as to determine
the acceptance of the lightest experimental materials
Analyzing Ideological Communities in Congressional Voting Networks
We here study the behavior of political party members aiming at identifying
how ideological communities are created and evolve over time in diverse
(fragmented and non-fragmented) party systems. Using public voting data of both
Brazil and the US, we propose a methodology to identify and characterize
ideological communities, their member polarization, and how such communities
evolve over time, covering a 15-year period. Our results reveal very distinct
patterns across the two case studies, in terms of both structural and dynamic
properties
Increased survival with enzalutamide in prostate cancer after chemotherapy
Contains fulltext :
108324.pdf (publisher's version ) (Open Access)BACKGROUND: Enzalutamide (formerly called MDV3100) targets multiple steps in the androgen-receptor-signaling pathway, the major driver of prostate-cancer growth. We aimed to evaluate whether enzalutamide prolongs survival in men with castration-resistant prostate cancer after chemotherapy. METHODS: In our phase 3, double-blind, placebo-controlled trial, we stratified 1199 men with castration-resistant prostate cancer after chemotherapy according to the Eastern Cooperative Oncology Group performance-status score and pain intensity. We randomly assigned them, in a 2:1 ratio, to receive oral enzalutamide at a dose of 160 mg per day (800 patients) or placebo (399 patients). The primary end point was overall survival. RESULTS: The study was stopped after a planned interim analysis at the time of 520 deaths. The median overall survival was 18.4 months (95% confidence interval [CI], 17.3 to not yet reached) in the enzalutamide group versus 13.6 months (95% CI, 11.3 to 15.8) in the placebo group (hazard ratio for death in the enzalutamide group, 0.63; 95% CI, 0.53 to 0.75; P<0.001). The superiority of enzalutamide over placebo was shown with respect to all secondary end points: the proportion of patients with a reduction in the prostate-specific antigen (PSA) level by 50% or more (54% vs. 2%, P<0.001), the soft-tissue response rate (29% vs. 4%, P<0.001), the quality-of-life response rate (43% vs. 18%, P<0.001), the time to PSA progression (8.3 vs. 3.0 months; hazard ratio, 0.25; P<0.001), radiographic progression-free survival (8.3 vs. 2.9 months; hazard ratio, 0.40; P<0.001), and the time to the first skeletal-related event (16.7 vs. 13.3 months; hazard ratio, 0.69; P<0.001). Rates of fatigue, diarrhea, and hot flashes were higher in the enzalutamide group. Seizures were reported in five patients (0.6%) receiving enzalutamide. CONCLUSIONS: Enzalutamide significantly prolonged the survival of men with metastatic castration-resistant prostate cancer after chemotherapy. (Funded by Medivation and Astellas Pharma Global Development; AFFIRM ClinicalTrials.gov number, NCT00974311.)
The Death and Rebirth of a Party System, Peru 1978-2001
This article evaluates structural, institutional, and actor-centered explanations of the collapse of the Peruvian party system around 1990 and its surprising partial recovery in 2001. It begins by describing the changes in the dependent variable, the emergence, collapse, and partial resurrection of the 1980s Peruvian party system. The next section examines the argument that the large size and rapid growth of the informal sector undermined the party system and led to its collapse. The author shows that the evidence does not support this argument. The article then examines changes in the electoral system. The author demonstrates that, contrary to theoretical expectations, the changes in the electoral system do not correlate with the observed changes in the party system. The final section shows that performance failure by political elites, including corruption in government, was more important than social cleavages or electoral institutions in the collapse and partial recovery of the party system.Yeshttps://us.sagepub.com/en-us/nam/manuscript-submission-guideline
Synchronised provisioning at the nest: parental coordination over care in a socially monogamous species
Bi-parental care is very common in birds, occurring in over 90% of species, and is expected to evolve whenever the benefits of enhanced offspring survival exceed the costs to both parents of providing care. In altricial species, where the nestlings are entirely dependent on the parents for providing food until fledging, reproductive success is related to the capacity of the parents to provision the offspring at the nest. The degree to which parents synchronise their visits to the nest is rarely considered by studies of bi-parental care, and yet may be an important component of parental care, affecting the outcome of the reproductive attempt, and the dynamics of sexual conflict between the parents. Here we studied this aspect of parental care in the long-tailed finch (Poephila acuticauda), a socially monogamous estrildid finch. We monitored parental nest visit rates and the degree of parental visit synchrony, and assessed their effects on reproductive success (e.g., brood size, number of offspring fledged and nestling growth).The frequency of nest visits in a day was low in this species (<1 visit/h), but there was a high level of synchrony by the two partners with 73% of visits made together. There was a correlation between the proportion of visits that were made by the pair together and the size of the brood at hatching, although it was not related to the number of fledglings a pair produced, or the quality of those offspring. We suggest that nest visit synchrony may primarily be driven by the benefit of parents being together whilst foraging away from the nest, or may reduce nest predation by reducing the level of activity around the nest throughout the day
Cidadania mediada : processos de democratização da política municipal no Brasil
This article discusses the notion that the persistence of “traditional” political practices weakens Brazil’s democracy.Drawing on the cases of three Brazilian municipalities administered by the Workers’ Party (PT), the author examines the space between “traditional” and “modern” and argues that successful democratization does not eradicate practices such as clientelism and patronage, but it tends to incorporate and build on these traditional political elements. Moreover, the article maintains that the democratization of municipal politics is inextricably bound up with the eradication of poverty and the construction of a responsive, state-based social safety net.<br /
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Use of anthropogenic material affects bird nest arthropod community structure: influence of urbanisation, and consequences for ectoparasites and fledging success
Nests are a critically important factor in determining the breeding success of many species of birds. Nevertheless, we have surprisingly little understanding of how local environment helps shape materials used in construction, how this differs among related species using similar nest sites, or if materials used directly or indirectly influence the numbers of offspring successfully reared. We also have little understanding of any potential links between nest construction and the assemblage of invertebrates which inhabit the nest and in particular, with ectoparasites. We addressed these questions by monitoring the success rates of nest-box using Blue Tits Cyanistes caeruleus and Great Tits Parus major, from rural, urban greenspace and urban garden settings. We collected used nests, identified arthropods present, and measured the proportions of highly processed anthropogenic materials used in their construction. Some 25% of Great Tit nest materials were of an anthropogenic source and this was consistent across habitats, while Blue Tits used little (1-2%) except in gardens (~16%), suggesting that Great Tits preferentially sought out these materials. In fledged nests, increasing use of anthropogenic material was associated with lower general arthropod diversity and ectoparasite predator abundance (Blue Tits only) but higher levels of Siphonapterans (fleas). Higher arthropod diversity was associated with lower flea numbers, suggesting that increased diversity played a role in limiting flea numbers. No direct link was found between breeding success and either anthropogenic material usage, or arthropod diversity and abundance. However, breeding success declined with increasing urbanisation in both species and increased with nest weight in Blue Tits. The interplay between urbanisation and bird ecology is complex; our work shows that subtle anthropogenic influences may have indirect and unexpected consequences for urban birds
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