Pilot Flying and Pilot Monitoring’s Aircraft State Awareness During Go-Around Execution in Aviation: A Behavioral and Eye Tracking Study

Objective: Examination of the performance and visual scanning of aircrews during final approach and an unexpected go-around maneuver. Background: Accident and incident analyses have revealed that go-around procedures are often imperfectly performed because of their complexity, their high time stress, and their rarity of occurrence that avails little time for practice. We wished to examine this experimentally and establish the frequency and nature of errors in both flight-performance and visual scanning. Method: We collected flight-performance (e.g., errors in procedures, excessive flight deviations) and eye-tracking data of 12 flight crews who performed final approach and go-around flight phases in realistic full-flight transport-category simulators. Results: The pilot performance results showed that two thirds of the crews committed errors including critical trajectory deviations during go-arounds, a precursor of accidents. Eye-tracking analyses revealed that the cross-checking process was not always efficient in detecting flight-path deviations when they occurred. Ocular data also highlighted different visual strategies between the 2 crew members during the 2 flight phases. Conclusion: This study reveals that the go-around is a challenging maneuver. It demonstrates the advantages of eye tracking and suggests that it is a valuable tool for the explicit training of attention allocation during go-arounds to enhance flight safety

Treatment of chronic hepatitis C in patients unresponsive to interferon. Interest of re-treatment combining interferon induction therapy and ribavirin (a multicenter pilot study)

Aim About 45% of patients with chronic hepatitis C are unresponsive to the present reference treatment combining pegelated interferon plus ribavirin; before pegylated interferon was available the non-response rate was around 60%. This open multicenter pilot study, initiated before pegylated interferon became available, was designed to evaluate, in patients unresponsive to interferon monotherapy, the rate of biological and virological response and side-effects of the ribivirin- alpha 2b interferon combination. Methods The combination protocol was ribavirin (1 to 1.2 g/d) plus alpha 2b interferon at induction doses (9 MU/d the first week; 4.5 MU/d the eleven following weeks; 3 MU/2 days the 36 following weeks). Results Among the 27 included patients, 17 (63%) were viremia-negative (PCR) after 12 weeks of treatment, 9 (33%) were complete responders (undetectable viremia and normal transaminases) at the end of treatment (48 weeks) and of follow-up (72 weeks). Patients with non-1, non-4 genotypes who derived full benefit from this therapeutic strategy (6/7 (86%) were complete responders: 4/5 with genotype 3 and 2/2 with genotype 5). Quality-of-life was impaired during treatment, especially during the first 12 weeks of high-dose interferon therapy. Conclusion While waiting for new therapeutic possibilities, these good results suggest interferon induction at the beginning of treatment remains a valid option

New Source of CP violation in B physics ?

In this talk we discuss how the down type left-right squark mixing in Supersymmetry can induce a new source of CP violation in the time dependent asymmtries in B --> phi K process. We use QCD improved factorization process to calculate the hadronic matrix element for the process and find the allowed parameter space for $\rho$ and $\phi$, the magnitude and phase of the down type LR(RL) squark mixing parameter $\delta^{bs}_{LR(RL)}$. In the same allowed regin we calculate the expected CP asymmtries in the $B \to \phi K^{*}$ process.Comment: 16 pages, Latex, 2 postscript figures, invited talk presented by N.G. Deshpande at the 9th Adriatic meeting, Dubrovnik, Croatia, 4-14 September, 2003. With updated reference

Neutrino mixing and large CP violation in B physics

We show that in see-saw models of neutrino mass a la SUSY SO(10), the observed large mixing in atmospheric neutrinos naturally leads to large b-s transitions. If the associated new CP phase turns out to be large, this SUSY contributions can drastically affect the CP violation in some of the B decay channels yielding the beta and gamma angles of the unitarity triangle. They can even produce sizeable CP asymmetries in some decay modes which are not CP violating in the standard model context. Hence the observed large neutrino mixing makes observations of low energy SUSY effect in some CP violating decay channels potentially promising in spite of the agreement between the Standard Model and data in K and B physics so far.Comment: References adde

Cluster number counts dependence on dark energy inhomogeneities and coupling to dark matter

Cluster number counts can be used to test dark energy models. We investigate dark energy candidates which are coupled to dark matter. We analyze the cluster number counts dependence on the amount of dark matter coupled to dark energy. Further more, we study how dark energy inhomogeneities affect cluster abundances. It is shown that increasing the coupling reduces significantly the cluster number counts, and that dark energy inhomogeneities increases cluster abundances. Wiggles in cluster number counts are shown to be a specific signature of coupled dark energy models. Future observations will possibly detect such oscillations and discriminate among the different dark energy models.Comment: 9 pages, 8 figures. Further extensions on section on discriminating models with future surveys. Accepted for publication in Mon. Not. Roy. Astro. So

Monitoring Cognitive and Emotional Processes Through Pupil and Cardiac Response During Dynamic Versus Logical Task

The paper deals with the links between physiological measurements and cognitive and emotional functioning. As long as the operator is a key agent in charge of complex systems, the definition of metrics able to predict his performance is a great challenge. The measurement of the physiological state is a very promising way but a very acute comprehension is required; in particular few studies compare autonomous nervous system reactivity according to specific cognitive processes during task performance and task related psychological stress is often ignored. We compared physiological parameters recorded on 24 healthy subjects facing two neuropsychological tasks: a dynamic task that require problem solving in a world that continually evolves over time and a logical task representative of cognitive processes performed by operators facing everyday problem solving. Results showed that the mean pupil diameter change was higher during the dynamic task; conversely, the heart rate was more elevated during the logical task. Finally, the systolic blood pressure seemed to be strongly sensitive to psychological stress. A better taking into account of the precise influence of a given cognitive activity and both workload and related task-induced psychological stress during task performance is a promising way to better monitor operators in complex working situations to detect mental overload or pejorative stress factor of error

The Minimal Supersymmetric Standard Model: Group Summary Report

CONTENTS: 1. Synopsis, 2. The MSSM Spectrum, 3. The Physical Parameters, 4. Higgs Boson Production and Decays, 5. SUSY Particle Production and Decays, 6. Experimental Bounds on SUSY Particle Masses, 7. References.Comment: 121 pages, latex + epsfig, graphicx, axodraw, Report of the MSSM working group for the Workshop "GDR-Supersym\'etrie",France. Rep. PM/98-4

On supersymmetric contributions to the CP asymmetry of the B -> phi K_S

We analyse the CP asymmetry of the B -> phi K_S process in general supersymmetric models. In the framework of the mass insertion approximation, we derive model independent limits for the mixing CP asymmetry. We show that chromomagnetic type of operator may play an important role in accounting for the deviation of the mixing CP asymmetry between B -> phi K_S and B -> J/psi K_S processes observed by Belle and BaBar experiments. A possible correlation between the direct and mixing CP asymmetry is also discussed. Finally, we apply our result in minimal supergravity model and supersymmetric models with non-universal soft terms.Comment: 19 pages, 3 figure

The Genetic Basis of Heterosis: Multiparental Quantitative Trait Loci Mapping Reveals Contrasted Levels of Apparent Overdominance Among Traits of Agronomical Interest in Maize (Zea mays L.)

Understanding the genetic bases underlying heterosis is a major issue in maize (Zea mays L.). We extended the North Carolina design III (NCIII) by using three populations of recombinant inbred lines derived from three parental lines belonging to different heterotic pools, crossed with each parental line to obtain nine families of hybrids. A total of 1253 hybrids were evaluated for grain moisture, silking date, plant height, and grain yield. Quantitative trait loci (QTL) mapping was carried out on the six families obtained from crosses to parental lines following the “classical” NCIII method and with a multiparental connected model on the global design, adding the three families obtained from crosses to the nonparental line. Results of the QTL detection highlighted that most of the QTL detected for grain yield displayed apparent overdominance effects and limited differences between heterozygous genotypes, whereas for grain moisture predominance of additive effects was observed. For plant height and silking date results were intermediate. Except for grain yield, most of the QTL identified showed significant additive-by-additive epistatic interactions. High correlation observed between heterosis and the heterozygosity of hybrids at markers confirms the complex genetic basis and the role of dominance in heterosis. An important proportion of QTL detected were located close to the centromeres. We hypothesized that the lower recombination in these regions favors the detection of (i) linked QTL in repulsion phase, leading to apparent overdominance for heterotic traits and (ii) linked QTL in coupling phase, reinforcing apparent additive effects of linked QTL for the other traits

A New Parametrization of the Seesaw Mechanism and Applications in Supersymmetric Models

We present a new parametrization of the minimal seesaw model, expressing the heavy-singlet neutrino Dirac Yukawa couplings $(Y_\nu)_{ij}$ and Majorana masses $M_{N_i}$ in terms of effective light-neutrino observables and an auxiliary Hermitian matrix $H.$ In the minimal supersymmetric version of the seesaw model, the latter can be related directly to other low-energy observables, including processes that violate charged lepton flavour and CP. This parametrization enables one to respect the stringent constraints on muon-number violation while studying the possible ranges for other observables by scanning over the allowed parameter space of the model. Conversely, if any of the lepton-flavour-violating process is observed, this measurement can be used directly to constrain $(Y_\nu)_{ij}$ and $M_{N_i}.$ As applications, we study flavour-violating $\tau$ decays and the electric dipole moments of leptons in the minimal supersymmetric seesaw model.Comment: Important references adde