The Future of Tourism Guidance in the Scope of Industry 4.0 and Next-Generation Technologies

Next-generation technologies such as robotics, the internet of things, artificial intelligence, sensors, cognitive technologies, nanotechnology, quantum computing, wearable technologies, augmented reality, intelligent signaling, and intelligent robots have led the fourth industrial revolution, often referred to as Industry 4.0. With the rapid advance of technology, most people today rely heavily on the internet to get information while traveling anywhere, because the use of technology has deeply penetrated daily life. The internet also makes travel easier and more convenient. For instance, it is possible to plan travel using smartphones and applications and at the same time meet instant travel needs as they arise. Therefore, the aim of this study is to examine tourism guidance within the scope of the super-smart tourists of the future, to determine the usage areas of next-generation technologies in the field of tourism guidance, and to give recommendations for tourism guidance in this regard

The Future of Tourism Guidance in the Scope of Industry 4.0 and Next-Generation Technologies (REPRINT)

Next-generation technologies such as robotics, the internet of things, artificial intelligence, sensors, cognitive technologies, nanotechnology, quantum computing, wearable technologies, augmented reality, intelligent signaling, and intelligent robots have led the fourth industrial revolution, often referred to as Industry 4.0. With the rapid advance of technology, most people today rely heavily on the internet to get information while traveling anywhere, because the use of technology has deeply penetrated daily life. The internet also makes travel easier and more convenient. For instance, it is possible to plan travel using smartphones and applications and at the same time meet instant travel needs as they arise. Therefore, the aim of this study is to examine tourism guidance within the scope of the super-smart tourists of the future, to determine the usage areas of next-generation technologies in the field of tourism guidance, and to give recommendations for tourism guidance in this regard

Use of colistin-containing products within the European Union and European Economic Area (EU/EEA): development of resistance in animals and possible impact on human and animal health.

&lt;p&gt;Since its introduction in the 1950s, colistin has been used mainly as a topical treatment in human medicine owing to its toxicity when given systemically. Sixty years later, colistin is being used as a last-resort drug to treat infections caused by multidrug-resistant (MDR) Pseudomonas aeruginosa, Acinetobacter baumannii and Enterobacteriaceae (e.g., Escherichia coli, Klebsiella pneumoniae), for which mortality can be high. In veterinary medicine, colistin has been used for decades for the treatment and prevention of infectious diseases. Colistin has been administered frequently as a group treatment for animal gastrointestinal infections caused by Gram-negative bacteria within intensive husbandry systems. Given the ever-growing need to retain the efficacy of antimicrobials used to treat MDR infections in humans, the use of colistin in veterinary medicine is being re-evaluated. Despite extensive use in veterinary medicine, there is limited evidence for the development of resistance to colistin and no evidence has been found for the transmission of resistance in bacteria that have been spread from animals to humans. Since surveillance for colistin resistance in animals is limited and the potential for such transmission exists, there is a clear need to reinforce systematic monitoring of bacteria from food-producing animals for resistance to colistin (polymyxins). Furthermore, colistin should only be used for treatment of clinically affected animals and no longer for prophylaxis of diseases, in line with current principles of responsible use of antibiotics.&lt;/p&gt;</p

Measurement of exclusive pion pair production in proton-proton collisions at √s=7 TeV with the ATLAS detector

The exclusive production of pion pairs in the process pp -&gt; pp pi(+)pi(-) has been measured at root s = 7TeV with the ATLAS detector at the LHC, using 80 mu b(-1) of low-luminosity data. The pion pairs were detected in the ATLAS central detector while outgoing protons were measured in the forwardATLASALFAdetector system. This represents the first use of proton tagging to measure an exclusive hadronic final state at the LHC. Across-sectionmeasurement is performed in two kinematic regions defined by the proton momenta, the pion rapidities and transverse momenta, and the pion-pion invariant mass. Cross-section values of 4.8 +/- 1.0 (stat)(-0.2) (+0.3)(syst) mu b and 9 +/- 6 (stat)(-2)(+2) (syst) mu b are obtained in the two regions; they are compared with theoretical models and provide a demonstration of the feasibility of measurements of this type

Luminosity determination in pppp collisions at s=13\sqrt{s}=13 TeV using the ATLAS detector at the LHC

The luminosity determination for the ATLAS detector at the LHC during Run 2 is presented, with $pp$ collisions at $\sqrt{s}=13$ TeV. The absolute luminosity scale is determined using van der Meer beam separation scans during dedicated running periods in each year, and extrapolated to the physics data-taking regime using complementary measurements from several luminosity-sensitive detectors. The total uncertainties in the integrated luminosities for each individual year of data-taking range from 0.9% to 1.1%, and are partially correlated between years. After standard data-quality selections, the full Run 2 $pp$ data sample corresponds to an integrated luminosity of $140.1\pm 1.2$ fb$^{-1}$, i.e. an uncertainty of 0.83%. A dedicated sample of low-pileup data recorded in 2017-18 for precision Standard Model physics measurements is analysed separately, and has an integrated luminosity of $338.1\pm 3.1$ pb$^{-1}$.The luminosity determination for the ATLAS detector at the LHC during Run 2 is presented, with pp collisions at a centre-of-mass energy $\sqrt{s}=13$ TeV. The absolute luminosity scale is determined using van der Meer beam separation scans during dedicated running periods in each year, and extrapolated to the physics data-taking regime using complementary measurements from several luminosity-sensitive detectors. The total uncertainties in the integrated luminosity for each individual year of data-taking range from 0.9% to 1.1%, and are partially correlated between years. After standard data-quality selections, the full Run 2 pp data sample corresponds to an integrated luminosity of $140.1\pm 1.2$ $\hbox {fb}^{-1}$, i.e. an uncertainty of 0.83%. A dedicated sample of low-pileup data recorded in 2017–2018 for precision Standard Model physics measurements is analysed separately, and has an integrated luminosity of $338.1\pm 3.1$ $\hbox {pb}^{-1}$.The luminosity determination for the ATLAS detector at the LHC during Run 2 is presented, with $pp$ collisions at $\sqrt{s}=13$ TeV. The absolute luminosity scale is determined using van der Meer beam separation scans during dedicated running periods in each year, and extrapolated to the physics data-taking regime using complementary measurements from several luminosity-sensitive detectors. The total uncertainties in the integrated luminosities for each individual year of data-taking range from 0.9% to 1.1%, and are partially correlated between years. After standard data-quality selections, the full Run 2 $pp$ data sample corresponds to an integrated luminosity of $140.1\pm 1.2$ fb$^{-1}$, i.e. an uncertainty of 0.83%. A dedicated sample of low-pileup data recorded in 2017-18 for precision Standard Model physics measurements is analysed separately, and has an integrated luminosity of $338.1\pm 3.1$ pb$^{-1}$

Measurement of exclusive pion pair production in proton–proton collisions at s=7 TeV\sqrt{s}={7}\,\text {TeV} with the ATLAS detector

International audienceThe exclusive production of pion pairs in the process $pp\rightarrow pp\pi ^+\pi ^-$ has been measured at $\sqrt{s}={7}\,\text {TeV}$ with the ATLAS detector at the LHC, using {80}\,{\upmu \textrm{b}}^{-1} of low-luminosity data. The pion pairs were detected in the ATLAS central detector while outgoing protons were measured in the forward ATLAS ALFA detector system. This represents the first use of proton tagging to measure an exclusive hadronic final state at the LHC. A cross-section measurement is performed in two kinematic regions defined by the proton momenta, the pion rapidities and transverse momenta, and the pion–pion invariant mass. Cross-section values of 4.8 \pm 1.0 \mathrm {\ (stat)} {~}^{+0.3}_{-0.2} \mathrm {\ (syst)}\ {\upmu \textrm{b}} and 9 \pm 6 \mathrm {\ (stat)} {~}^{+2}_{-2} \mathrm {\ (syst)}\ {\upmu \textrm{b}} are obtained in the two regions; they are compared with theoretical models and provide a demonstration of the feasibility of measurements of this type