The central parsecs of M87: jet emission and an elusive accretion disc

We present the first simultaneous spectral energy distribution (SED) of M87 core at a scale of 0.4 arcsec ($\sim 32\, \rm{pc}$) across the electromagnetic spectrum. Two separate, quiescent, and active states are sampled that are characterized by a similar featureless SED of power-law form, and that are thus remarkably different from that of a canonical active galactic nuclei (AGN) or a radiatively inefficient accretion source. We show that the emission from a jet gives an excellent representation of the core of M87 core covering ten orders of magnitude in frequency for both the active and the quiescent phases. The inferred total jet power is, however, one to two orders of magnitude lower than the jet mechanical power reported in the literature. The maximum luminosity of a thin accretion disc allowed by the data yields an accretion rate of $< 6 \times 10^{-5}\, \rm{M_\odot \, yr^{-1}}$, assuming 10% efficiency. This power suffices to explain M87 radiative luminosity at the jet-frame, it is however two to three order of magnitude below that required to account for the jet's kinetic power. The simplest explanation is variability, which requires the core power of M87 to have been two to three orders of magnitude higher in the last 200 yr. Alternatively, an extra source of power may derive from black hole spin. Based on the strict upper limit on the accretion rate, such spin power extraction requires an efficiency an order of magnitude higher than predicted from magnetohydrodynamic simulations, currently in the few hundred per cent range.Comment: 18 pages, 6 figures. Accepted for publication in MNRA

Estudio morfológico de la hembra, macho y ninfa de Rallinyssus Candistigmus Strandtmann, 1948 (Acarina: Rhinonyssidae), parásito de las fosas nasales de Flica Atra Atra L. granadinas

This paper presents a study of female, male and nymph of Rallinyssus caudistigmus STRANDTMANN, 1948, from the nasal cavities of Fulica atra atra L.Se estudian morfológieamente la hembra, macho y ninfa de Raziínyssus caudístigmus STRANDTMANN, 1948, encontrados en las fosas nasales de la focha común. Fulíca atra atra L, capturada en la provincia de Granada

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.This paper presents a morphological study of Sternostoma turdi Zumpt and Till, 1955, (female, male and nymph), Sternostoma loxiae Fain, 1965 (female) and Sternostoma christinae Guevara-Benitez, Lopez-Roman and Ubeda-Ontiveros, 1974 (male)

Unbiased large spectroscopic surveys of galaxies selected by SPICA using dust bands

The mid-infrared (IR) range contains many spectral features associated with large molecules and dust grains such as polycyclic aromatic hydrocarbons (PAHs) and silicates. These are usually very strong compared to fine-structure gas lines, and thus valuable in studying the spectral properties of faint distant galaxies. In this paper, we evaluate the capability of low-resolution mid-IR spectroscopic surveys of galaxies that could be performed by SPICA. The surveys are designed to address the question how star formation and black hole accretion activities evolved over cosmic time through spectral diagnostics of the physical conditions of the interstellar/circumnuclear media in galaxies. On the basis of results obtained with Herschel far-IR photometric surveys of distant galaxies and Spitzer and AKARI near- to mid-IR spectroscopic observations of nearby galaxies, we estimate the numbers of the galaxies at redshift z > 0.5, which are expected to be detected in the PAH features or dust continuum by a wide (10 deg^2) or deep (1 deg^2) blind survey, both for a given observation time of 600 hours. As by-products of the wide blind survey, we also expect to detect debris disks, through the mid-IR excess above the photospheric emission of nearby main-sequence stars, and we estimate their number. We demonstrate that the SPICA mid-IR surveys will efficiently provide us with unprecedentedly large spectral samples, which can be studied further in the far-IR with SPICA.Comment: Paper accepted for publication on PASA on 18th October 2017, as part of the SPICA Special Issu

The 1989 and 2015 outbursts of V404 Cygni: a global study of wind-related optical features

The black hole transient V404 Cygni exhibited a bright outburst in June 2015 that was intensively followed over a wide range of wavelengths. Our team obtained high time resolution optical spectroscopy (~90 s), which included a detailed coverage of the most active phase of the event. We present a database consisting of 651 optical spectra obtained during this event, that we combine with 58 spectra gathered during the fainter December 2015 sequel outburst, as well as with 57 spectra from the 1989 event. We previously reported the discovery of wind-related features (P-Cygni and broad-wing line profiles) during both 2015 outbursts. Here, we build diagnostic diagrams that enable us to study the evolution of typical emission line parameters, such as line fluxes and equivalent widths, and develop a technique to systematically detect outflow signatures. We find that these are present throughout the outburst, even at very low optical fluxes, and that both types of outflow features are observed simultaneously in some spectra, confirming the idea of a common origin. We also show that the nebular phases depict loop patterns in many diagnostic diagrams, while P-Cygni profiles are highly variable on time-scales of minutes. The comparison between the three outbursts reveals that the spectra obtained during June and December 2015 share many similarities, while those from 1989 exhibit narrower emission lines and lower wind terminal velocities. The diagnostic diagrams presented in this work have been produced using standard measurement techniques and thus may be applied to other active low-mass X-ray binaries.Comment: Accepted for publication in MNRAS. 23 pages paper, plus a 9 pages appendix with extra tables and figures. 18 figures are included in the paper and 8 in the appendi

Aryl hydrocarbon receptor-mediated activity of particulate organic matter from the Paso del Norte airshed along the U.S.-Mexico border.

In this study, we determined the biologic activity of dichloromethane-extracted particulate matter < 10 micro m in aerodynamic diameter (PM10) obtained from filters at three sites in the Paso del Norte airshed, which includes El Paso, Texas, USA; Juarez, Chihuahua, Mexico, and Sunland Park, New Mexico, USA. The extracts were rich in polycyclic aromatic hydrocarbons (PAHs) and had significant biologic activity, measured using two in vitro assay systems: ethoxyresorufin-(O-deethylase (EROD) induction and the aryl hydrocarbon-receptor luciferase reporter system. In most cases, both EROD (5.25 pmol/min/mg protein) and luciferase activities (994 relative light units/mg) were highest in extracts from the Advance site located in an industrial neighborhood in Juarez. These values represented 58% and 55%, respectively, of induction associated with 1 micro M ss-naphthoflavone exposures. In contrast, little activity was observed at the Northeast Clinic site in El Paso, the reference site. In most cases, luciferase and EROD activity from extracts collected from the Tillman Health Center site, situated in downtown El Paso, fell between those observed at the other two sites. Overall, a statistically significant correlation existed between PM10 and EROD and luciferase activities. Chemical analysis of extracts collected from the Advance site demonstrated that concentrations of most PAHs were higher than those reported in most other metropolitan areas in the United States. Calculations made with these data suggest a cancer risk of 5-12 cases per 100,000 people. This risk estimate, as well as comparisons with the work of other investigators, raises concern regarding the potential for adverse health effects to the residents of this airshed. Further work is needed to understand the sources, exposure, and effects of PM10 and particulate organic material in the Paso del Norte airshed

Circulating gluten-specific FOXP3⁺CD39⁺ regulatory T cells have impaired suppressive function in patients with celiac disease

Background Celiac disease is a chronic immune-mediated inflammatory disorder of the gut triggered by dietary gluten. Although the effector T-cell response in patients with celiac disease has been well characterized, the role of regulatory T (Treg) cells in the loss of tolerance to gluten remains poorly understood. Objective We sought to define whether patients with celiac disease have a dysfunction or lack of gluten-specific forkhead box protein 3 (FOXP3)+ Treg cells. Methods Treated patients with celiac disease underwent oral wheat challenge to stimulate recirculation of gluten-specific T cells. Peripheral blood was collected before and after challenge. To comprehensively measure the gluten-specific CD4+ T-cell response, we paired traditional IFN-γ ELISpot with an assay to detect antigen-specific CD4+ T cells that does not rely on tetramers, antigen-stimulated cytokine production, or proliferation but rather on antigen-induced coexpression of CD25 and OX40 (CD134). Results Numbers of circulating gluten-specific Treg cells and effector T cells both increased significantly after oral wheat challenge, peaking at day 6. Surprisingly, we found that approximately 80% of the ex vivo circulating gluten-specific CD4+ T cells were FOXP3+CD39+ Treg cells, which reside within the pool of memory CD4+CD25+CD127lowCD45RO+ Treg cells. Although we observed normal suppressive function in peripheral polyclonal Treg cells from patients with celiac disease, after a short in vitro expansion, the gluten-specific FOXP3+CD39+ Treg cells exhibited significantly reduced suppressive function compared with polyclonal Treg cells. Conclusion This study provides the first estimation of FOXP3+CD39+ Treg cell frequency within circulating gluten-specific CD4+ T cells after oral gluten challenge of patients with celiac disease. FOXP3+CD39+ Treg cells comprised a major proportion of all circulating gluten-specific CD4+ T cells but had impaired suppressive function, indicating that Treg cell dysfunction might be a key contributor to disease pathogenesis