456 research outputs found

    Discovering History: The History of the Ice House Complex

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    A gift to Gettysburg College in 1990 from George W. Olinger and Mae E. Olinger, life long residents of Gettysburg, zestful supporters of local history, common sense preservationists and quiet humanitarians. Their gift of these historic buildings and land underscores the Olingers\u27 lasting love for the town of Gettysburg and the College. Between 1786 and 1990, this area housed a Presbyterian Church and a cemetery, a livery, shirt factory, carriage making complex, blacksmith shop, a wood-works plant, a cutlery, a bottlery, two brewing companies, an ice cream factory, an ice and cold storage facility, a roofing business, personal residences and offices which were all central to the evolving industrial, commercial, economic, and social fabric of Gettysburg’s rich history. Course Information: Course Title: HIST 300: Historical Method Academic Term: Fall 2009 Course Instructor: Dr. Michael J. Birkner \u2772 Hidden in Plain Sight is a collection of student papers on objects that are hidden in plain sight around the Gettysburg College campus. Topics range from the Glatfelter Hall gargoyles to the statue of Eisenhower and from historical markers to athletic accomplishments. You can download the paper in pdf format and click View Photo to see the image in greater detail.https://cupola.gettysburg.edu/hiddenpapers/1000/thumbnail.jp

    Rebuilding the Special Relationship: Ambassador Sir Harold Caccia and the Reconstruction of Relations between the United States and the United Kingdom

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    This paper focuses on the rejuvenation of the \u27special relationship\u27 between the United States and Great Britain during the presidency of Dwight D. Eisenhower. Relations between the two nations suffered after the Suez Canal Crisis of 1956, and the next two years were devoted to repairing the necessary close relationship between the two allies. The research highlights the role of United Kingdom Ambassador to Washington, Sir Harold Caccia, during the time of rebuilding the close relations

    Biomass Allocation is an Important Determinant of the Tannin Concentration in Growing Plants

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    Background and aims Condensed tannins (CTs) in the diet affect consumers in a concentration-dependent manner. Because of their importance in plant defence against herbivores and pathogens as well as their potential application against gastrointestinal parasites of ruminants in agronomy, an understanding of the seasonal dynamics of CT concentrations during plant growth is essential. Methods Over a vegetation period, CT concentrations in leaves, stems and roots and the biomass proportions between these organs were investigated in Onobrychis viciifolia, Lotus corniculatus and Cichorium intybus. Based on the experimental data, a model has been suggested to predict CT concentrations in harvestable biomass of these species. Key Results During the experiment, leaf mass fractions of plants decreased from 85, 64, 85 to 30, 18, 39% d. wt in Onobrychis, Lotus and Cichorium, respectively, and proportions of stems and roots increased accordingly. While CT concentrations almost doubled in leaves in Onobrychis (from 52 to 86mg g−1 d. wt, P<0·001) and Lotus (from 25 to 54mg g−1 d. wt, P<0·001), they were stable at low levels in expanding leaves of Cichorium (5mg g−1 d. wt) and in stems and roots of all investigated species. Due to an inverse effect of the increasing CT concentrations in leaves and simultaneous dilution from increasing proportions of ‘CT-poor' stems, CT concentrations in harvestable biomass were stable over time in all investigated species: 62, 26 and 5mg g−1 d. wt for Onobrychis, Lotus and Cichorium, respectively. Conclusions As a consequence of the unequal distribution of tannins in different plant parts and due to the changing biomass proportions between them, various herbivores (e.g. a leaf-eating insect and a grazing ruminant) may find not only different concentrations of CT in their diets but also different CT dynamics during the season. For the prediction of seasonal variations of CT concentrations, biomass allocation and accumulation of none-CT plant material are likely to be as important predictors as the knowledge of CT synthesis and its regulatio

    Effect of Preanalytical Processing of ThinPrep Specimens on Detection of High-Risk Human Papillomavirus by the Aptima HPV Assay

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    Two important preanalytical protocols performed on liquid-based cytological specimens, namely, automated cytology processing and glacial acetic acid (GAA) treatment, may occur prior to the arrival of specimens in a molecular diagnostics laboratory. Ninety-two ThinPrep vials previously positive for high-risk human papillomavirus (HPV) via the Cervista HPV HR test were preselected and alternated with 92 previously negative ThinPrep vials. The specimen set was processed in a consecutive fashion by an automated cytology processor without fastidious decontamination precautions. Carryover potential was subsequently assessed by performance of the Aptima HPV assay on aliquots from reprocessed ThinPrep vials. All previously negative ThinPrep vials yielded a negative result following routine automated cytology processing, despite close proximity to known-positive ThinPrep vials. In separate experiments, aliquots from 236 ThinPrep vials were forwarded for tandem analysis with and without GAA treatment. Data from GAA- and mock-treated specimens generated by Aptima HPV were compared to correlate data generated by Cervista. A 99.2% concordance of Aptima HPV results from GAA-treated and mock-treated specimens was noted. This result differed from the concordance result derived from Cervista (91.5%; P \u3c 0.0002). Of the initially positive Cervista results, 21.9% reverted to negative following GAA treatment; the correlate value was 2.7% for Aptima HPV (P = 0.01). While deleterious effects of GAA treatment on genomic DNA were noted with Cervista (P = 0.0015), GAA treatment had no significant effects on Aptima HPV specimen signal/cutoff ratios or amplification of internal control RNA (P ≥ 0.07). The validity of an Aptima HPV result is independent of GAA treatment and routine automated cytology processing

    Approaches for Improving Lumped Parameter Thermal Networks for Outer Rotor SPM Machines

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    This work is about the transient modeling of the thermal characteristics of outer rotor SPM machines by considering a lumped parameter thermal network based approach. The machine considered here poses particular challenges for the modeling, e.g., due to the semi-closed stator surrounded by a rotor bell that provides a speed-dependent cooling of the stator coils. Starting from a simpler basic network configuration, model extensions and refinements are presented and discussed. The subsequent parameter identification is done by means of an initial design of experiments based sampling, and a subsequent single-objective and also a multi-objective optimization of error functions for the components' temperatures. Analyzing the therefrom derived Pareto fronts and the consequent tradeoff regarding achievable minimum modeling errors for different system's components gives insights into where and how the modeling can be further improved. All the investigations are based on experimental results obtained through operating a particularly developed test setup

    Nitrogen cycle disruption through the application of de-icing salts on upland highways

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    It is hypothesized that episodic introductions of road salt severely disrupt the soil nitrogen cycle at a range of spatial and temporal scales. A field-scale study has confirmed impacts on the nitrogen cycle in soil, soil solution and river samples. There is evidence that ammonium-N retention on cation exchange sites has been reduced by the presence of sodium ions, and that ammonium-N has been flushed from the exchange sites. Increases in soil pH have been caused in naturally acidic uplands. These have enhanced mineralization of organic-N, especially nitrification, leading to a reduction in the mineralizable-N pool of roadside soils. There is evidence to support the hypothesis that organic matter content has been lowered over decades either through desorption or dispersal processes. Multiple drivers are identified that contribute to the disruption of nitrogen cycling processes, but their relative importance is difficult to quantify unequivocally. The influence of road salt on soil and soil solution declines with distance from the highway, but impacts on water chemistry in a local stream are still strongly evident at some distance from the road

    Measurement-Based Identification of Lumped Parameter Thermal Networks for sub-Kw Outer Rotor PM Machines

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    This work is on deriving precise lumped parameter thermal networks for modeling the transient thermal characteristics of electric machines under variable load conditions. The goal is to facilitate an accurate estimation of the temperatures of critical machines' components and to allow for running the derived model in real time to adapt the motor control based on the load history and maximum permissible temperatures. Consequently, the machine's capabilities can be exhausted at best considering a highly-utilized drive. The model shall be as simple as possible without sacrificing the exactness of the predicted temperatures. Accordingly, a specific lumped parameter thermal network topology was selected and its characteristics are explained in detail. The measurement data based optimization of its critical parameters through an evolutionary optimization strategy, and the therefore utilized experimental setup will be described in detail here. Measurement cycles were recorded for modeling and verification purposes including both static and dynamic test cycles with changing load torque and speed requirements. Applying the proposed hybrid approach for determining the model's parameters through involving physics-based equations as well as numerical optimization followed a significant improvement of the preciseness of the predicted motor temperatures compared to solely determining the networks's coefficients based on expert knowledge. Thereby, the validation included both the original measurement data as well as extra measurement runs. The proposed and applied strategy provides an excellent basis for future thermal modeling of electric machines

    Communication in the Third Dimension: Song Perch Height of Rivals Affects Singing Response in Nightingales

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    Many animals use long-range signals to compete over mates and resources. Optimal transmission can be achieved by choosing efficient signals, or by choosing adequate signalling perches and song posts. High signalling perches benefit sound transmission and reception, but may be more risky due to exposure to airborne predators. Perch height could thus reflect male quality, with individuals signalling at higher perches appearing as more threatening to rivals. Using playbacks on nightingales (Luscinia megarhynchos), we simulated rivals singing at the same height as residents, or singing three metres higher. Surprisingly, residents increased song output stronger, and, varying with future pairing success, overlapped more songs of the playback when rivals were singing at the same height than when they were singing higher. Other than expected, rivals singing at the same height may thus be experienced as more threatening than rivals singing at higher perches. Our study provides new evidence that territorial animals integrate information on signalling height and thus on vertical cues in their assessment of rivals

    Atlantic circulation change still uncertain

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    Deep oceanic overturning circulation in the Atlantic (Atlantic Meridional Overturning Circulation, AMOC) is projected to decrease in the future in response to anthropogenic warming. Caesar et al. 1 argue that an AMOC slowdown started in the 19 th century and intensified during the mid-20th century. Although the argument and selected evidence proposed have some merits, we find that their conclusions might be different if a more complete array of data available in the North Atlantic region had been considered. We argue that the strength of AMOC over recent centuries is still poorly constrained and the expected slowdown may not have started yet.K.H.K. acknowledges funding from NOAA grant NA20OAR4310481. D.E.A. and B.L.O.-B. acknowledge support from the National Center for Atmospheric Research, which is a major facility sponsored by the National Science Foundation under cooperative agreement no. 1852977. N.M.W. acknowledges support from a NOAA Climate and Global Change Postdoctoral Fellowship. M.F.J. acknowledges support from NSF award OCE-1846821 and C.M.L. acknowledges support from NSF award OCE-1805029. This is UMCES contribution 6062.Peer ReviewedArticle signat per 17 autors/es: University of Maryland Center for Environmental Science, Chesapeake Biological Laboratory, Solomons, MD, USA: K. Halimeda Kilbourne / Department of Geological and Atmospheric Sciences, Iowa State University, Ames, IA, USA: Alan D. Wanamaker / Geography Department, Durham University, Durham, UK: Paola Moffa-Sanchez / Centre for Geography and Environmental Sciences, University of Exeter, Penryn, UK: David J. Reynolds, Paul G. Butler & James Scourse / Climate and Global Dynamics Laboratory, National Center for Atmospheric Research, Boulder, CO, USA: Daniel E. Amrhein & Bette L. Otto-Bliesner / Woods Hole Oceanographic Institution, Falmouth, MA, USA: Geoffrey Gebbie & Nina M. Whitney / Cooperative Institute for Marine and Atmospheric Studies, University of Miami, Miami, FL, USA: Marlos Goes / Atlantic Oceanographic and Meteorological Laboratory, National Oceanic and Atmospheric Administration, Miami, FL, USA: Marlos Goes / Department of the Geophysical Sciences, The University of Chicago, Chicago, IL, USA: Malte F. Jansen / Oceanography Department, Atmospheric and Environmental Research, Inc., Texas, TX, USA: Christopher M. Little / US Geological Survey, St Petersburg Coastal and Marine Science Center, St Petersburg, FL, USA: Madelyn Mette / Barcelona Supercomputing Center, Barcelona, Spain: Eduardo Moreno-Chamarro & Pablo Ortega / Graduate School of Oceanography, University of Rhode Island, Kingston, RI, USA: Thomas Rossby / University Corporation of Atmospheric Research, Boulder, CO, USA: Nina M. WhitneyPostprint (author's final draft)Matters Arising published on 17 February 2022. The Original Article was published on 25 February 2021

    Fixing the conformation of calix[4]arenes: When are three carbons not enough?

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    Calix[4]arenes are unique macrocycles that through judicious functionalisation at the lower-rim can be either fixed in one of four conformations or remain conformationally flexible. Introduction of propynyl or propenyl groups unexpectedly provides a new possibility; a unidirectional conformational switch, with the 1,3-alternate and 1,2-alternate conformers switching to the partial cone conformation, whilst the cone conformation is unchanged, under standard experimental conditions. Using 1H NMR kinetic studies, rates of switching have been shown to be dependent on the starting conformation, upper-rim substituent, where reduction in bulk enables faster switching, solvent and temperature with 1,2-alternate conformations switching fastest. Ab initio calculations (DFT) confirmed the relative stabilities of the conformations and point towards the partial cone conformer being the most stable of the four. The potential impact on synthesis through the ‘click’ reaction has been investigated and found not to be significant
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