102 research outputs found

    Software JClic como Método de Enseñanza para la Lectura

    Get PDF
    El software educativo JClic es una herramienta de apoyo pedagógico; que puede dar soluciones significativas a los docentes, ante la gran exigencia de usar una estrategia innovadora para fortalecer la lectura de los estudiantes. Este estudio tiene como propósito; Promover actividades pedagógicas para el uso del software JClic como método de enseñanza para fortalecer la lectura de los estudiantes, siendo la lectura; una de las grandes debilidades académicas en la actualidad. Con la creación de estrategias de enseñanza mediante este software didáctico, se afianzará el aprendizaje de la lectura. La direccionalidad de la investigación adopta un enfoque cualitativo, inmerso en el paradigma socio crítico, con una modalidad de investigación acción participativa, teniendo como diseño las fases de; diagnóstico, planificación, ejecución y evaluación. Para obtener información veraz, se consideraron como actores sociales a todos los docentes de aula que hacen vida en una escuela específica, y para precisar la información se tomaron como informantes clave a tres (3) docentes de aula, en virtud de que cumplen con las cualidades necesarias para apoyar teóricamente la investigación a través de la entrevista semiestructurada, a su vez, se empleó la técnica de la observación participante, obteniendo una validez descriptiva e interpretativa de la información

    Saturn's icy satellites and rings investigated by Cassini - VIMS. III. Radial compositional variability

    Full text link
    In the last few years Cassini-VIMS, the Visible and Infared Mapping Spectrometer, returned to us a comprehensive view of the Saturn's icy satellites and rings. After having analyzed the satellites' spectral properties (Filacchione et al. (2007a)) and their distribution across the satellites' hemispheres (Filacchione et al. (2010)), we proceed in this paper to investigate the radial variability of icy satellites (principal and minor) and main rings average spectral properties. This analysis is done by using 2,264 disk-integrated observations of the satellites and a 12x700 pixels-wide rings radial mosaic acquired with a spatial resolution of about 125 km/pixel. The comparative analysis of these data allows us to retrieve the amount of both water ice and red contaminant materials distributed across Saturn's system and the typical surface regolith grain sizes. These measurements highlight very striking differences in the population here analyzed, which vary from the almost uncontaminated and water ice-rich surfaces of Enceladus and Calypso to the metal/organic-rich and red surfaces of Iapetus' leading hemisphere and Phoebe. Rings spectra appear more red than the icy satellites in the visible range but show more intense 1.5-2.0 micron band depths. The correlations among spectral slopes, band depths, visual albedo and phase permit us to cluster the saturnian population in different spectral classes which are detected not only among the principal satellites and rings but among co-orbital minor moons as well. Finally, we have applied Hapke's theory to retrieve the best spectral fits to Saturn's inner regular satellites using the same methodology applied previously for Rhea data discussed in Ciarniello et al. (2011).Comment: 44 pages, 27 figures, 7 tables. Submitted to Icaru

    L'Italia come modello per l'Europa e per il mondo nelle politiche sanitarie per il trattamento dell'epatite cronica da HCV

    Get PDF
    The World Health Organization foresees the elimination of HCV infection by 2030. In light of this and the curre nt, nearly worldwide, restriction in direct-acting agents (DAA) accessibility due to their high price, we aimed to evaluate the cost-effectiveness of two alternative DAA treatment policies: Policy 1 (universal): treat all patients, regardless of the fibrosis stage; Policy 2 (prioritized): treat only priori tized patients and delay treatment of the remaining patients until reaching stage F3. T he model was based on patient’s data from the PITER cohort. We demonstrated that extending HC V treatment of patients in any fibrosis stage improves health outcomes and is cost-effective

    Software JClic como Método de Enseñanza para la Lectura

    No full text
    JClic educational software is a pedagogical support tool; that can give meaningful solutions to teachers, before the great demand to use an innovative strategy to strengthen the reading of students. This study is for the purpose; Promote pedagogical activities for the use of JClic software as a teaching method to improve student Reading, being reading; one of the great academic weaknesses today, with the creation of teaching strategies through this didactic software, the learning of reading will be strengthened. The directionality of the research adopts a qualitative approach, immersed in the critical partner paradigm, with a modality of participatory action research, having as design the phases of; diagnosis, planning, execution and evaluation. To obtain truthful information, all the classroom teachers who live in a specific school were considered as social actors, and to clarify the information, three (3) classroom teachers were taken as key informants, by virtue of fulfilling the necessary qualities to theoretically support research through the semi-structured interview, at the same time, the technique of participant observation was used, obtaining a descriptive and interpretative validity of the information. Determining, that this software; acts as a teaching medium of great scope for the teacher in their teaching methods for reading.El software educativo JClic es una herramienta de apoyo pedagógico; que puede dar soluciones significativas a los docentes, ante la gran exigencia de usar una estrategia innovadora para fortalecer la lectura de los estudiantes. Este estudio tiene como propósito; Promover actividades pedagógicas para el uso del software JClic como método de enseñanza para fortalecer la lectura de los estudiantes, siendo la lectura; una de las grandes debilidades académicas en la actualidad. Con la creación de estrategias de enseñanza mediante este software didáctico, se afianzará el aprendizaje de la lectura. La direccionalidad de la investigación adopta un enfoque cualitativo, inmerso en el paradigma socio crítico, con una modalidad de investigación acción participativa, teniendo como diseño las fases de; diagnóstico, planificación, ejecución y evaluación. Para obtener información veraz, se consideraron como actores sociales a todos los docentes de aula que hacen vida en una escuela específica, y para precisar la información se tomaron como informantes clave a tres (3) docentes de aula, en virtud de que cumplen con las cualidades necesarias para apoyar teóricamente la investigación a través de la entrevista semiestructurada, a su vez, se empleó la técnica de la observación participante, obteniendo una validez descriptiva e interpretativa de la información

    Leveraging Spatio-Temporal Autocorrelation to Improve the Forecasting of the Energy Consumption in Smart Grids

    No full text
    Smart grids are networks that distribute electricity by relying on advanced communication technologies, sensor measurements, and predictive methods, to quickly adapt the network behavior to different possible scenarios. In this context, the adoption of machine learning approaches to forecast the customer energy consumption is essential to optimize network planning operations, avoid unnecessary energy production, and minimize power shortages. However, classical forecasting methods are not able to take into account spatial and temporal auto-correlation phenomena, naturally introduced by the spatial proximity of consumers, and by the seasonality of the energy consumption trends.In this paper, we investigate the adoption of several solutions to take into account spatio-temporal autocorrelation phenomena. Specifically, we investigate the contribution provided by the explicit representation of temporal i-nformation related to historical measurements using multiple strategies, as well as that of simultaneously predicting multiple future consumption measurements in a multi-step predictive setting. Finally, we investigate the effectiveness of injecting descriptive features to make the learning methods aware of the spatial closeness among the consumers.The experimental evaluation performed on a real-world electrical network demonstrated the positive contribution of making the models aware of spatio-temporal autocorrelation phenomena, and proved the overall superiority of models based on the multi-step predictive setting

    Non-invasive Prenatal Testing Using Fetal DNA

    No full text
    Non-invasive prenatal diagnosis (NIPD) is based on fetal DNA analysis starting from a simple peripheral blood sample, thus avoiding risks associated with conventional invasive techniques. During pregnancy, the fetal DNA increases to approximately 3–13% of the total circulating free DNA in maternal plasma. The very low amount of circulating cell-free fetal DNA (ccffDNA) in maternal plasma is a crucial issue, and requires specific and optimized techniques for ccffDNA purification from maternal plasma. In addition, highly sensitive detection approaches are required. In recent years, advanced ccffDNA investigation approaches have allowed the application of non-invasive prenatal testing (NIPT) to determine fetal sex, fetal rhesus D (RhD) genotyping, aneuploidies, micro-deletions and the detection of paternally inherited monogenic disorders. Finally, complex and innovative technologies such as digital polymerase chain reaction (dPCR) and next-generation sequencing (NGS) (exhibiting higher sensitivity and/or the capability to read the entire fetal genome from maternal plasma DNA) are expected to allow the detection, in the near future, of maternally inherited mutations that cause genetic diseases. The aim of this review is to introduce the principal ccffDNA characteristics and their applications as the basis of current and novel NIPT
    corecore