Estudio de los niveles de razonamiento de Van Hiele en alumnos de centros de enseñanza vulnerables de educación media en Chile

Presentamos los resultados de una investigación enfocada a mejorar el aprendizaje de la geometría y la adquisición de destrezas de razonamiento matemático de estudiantes de 2.º año medio de centros de enseñanza secundaria vulnerables de Chile. Se ha diseñado un experimento de enseñanza, con grupos experimental y control, basado en una unidad de enseñanza, diseñada de acuerdo con los niveles y las fases de Van Hiele, y en un pretest y un postest, para evaluar el cambio en el nivel de razonamiento de los estudiantes derivado de la intervención. Los resultados muestran una diferencia significativa, a favor del grupo experimental, en el desarrollo del nivel de razonamiento de los estudiantes.Presentem els resultats d'una recerca enfocada a millorar l'aprenentatge de la geometria i l'adquisició de destreses de raonament matemàtic d'estudiants de 2n. any mitjà de centres d'ensenyament secundari vulnerables de Xile. S'ha dissenyat un experiment d'ensenyament, amb grups experimental i control, basat en una unitat d'ensenyament, dissenyada d'acord amb els nivells i les fases de Van Hiele, i en un pretest i un postest, per avaluar el canvi en el nivell de raonament dels estudiants derivat de la intervenció. Els resultats mostren una diferència significativa, a favor del grup experimental, en el desenvolupament del nivell de raonament dels estudiants.We present results of a research aimed at improving the learning of geometry and the acquisition of mathematical reasoning skills of students in 2nd year of secondary education in vulnerable centres of Chile. We have designed a teaching experiment, with experimental and control groups, based on a teaching unit, designed according to the Van Hiele levels and phases, and a pretest and postest, to assess the change in students' Van Hiele level of reasoning after the intervention. The results show a significant difference, in favour of the experimental group, in the development of students' level of reasoning

Diseño De Un Modelo De Balanced Scorecard Para La Optimización De Tiempo De Las Rutas De Transporte Público Urbano En Una Empresa Privada Del Municipio De Chía

Diseñar un modelo de gestión basado en la metodología del Balanced Scorecard (Cuadro de Mando Integral) para lograr la optimización en el tiempo de las rutas de transporte público urbano en una empresa del municipio de Chía.La planeación estratégica es uno de los pilares fundamentales dentro de la gestión empresarial que permite integrar las fortalezas con las oportunidades, analizando las debilidades y amenazas y direccionando correctamente el logro de los objetivos de la organización, generando a su vez, satisfacción a los usuarios internos y externos. Esta investigación diseña un modelo de gestión basado en la metodología del Balanced Scorecard (Cuadro de Mando Integral) para así lograr la optimización en el tiempo de las rutas de transporte público urbano en una empresa del municipio de Chía; este estudio tiene un enfoque de metodología mixta, cuenta con tres partes, la inicial de revisión documental, continuando así, con la segunda denominada trabajo de campo en la cual se aplicaron herramientas de diagnóstico como encuestas y entrevistas a la población objeto de este estudio, para concluir con la tercera fase donde se recopilo la información obtenida con el objeto de realizar el correspondiente análisis e integración de resultados, que permitieron el diseño de una herramienta útil, confiable y practica que ayude a complementar y facilitar la toma de decisiones en pro del bienestar empresarial, económico, social y medio ambiental para el municipio.Strategic planning is one of the fundamental pillars within business management that allows integrating strengths with opportunities by correctly directing the achievement of the organization's objectives, generating, in turn, satisfaction to internal and external users. This research aims to design a management model based on the Balanced Scorecard methodology to achieve optimization in time of urban public transport routes in a company in the municipality of Chia, in the light of social responsibility; This study has a mixed methodology approach, has three phases, the initial document review, continuing with the second phase of field work in which diagnostic tools such as surveys and interviews were applied to the population under study. , to conclude with the third phase where the information obtained to perform the corresponding analysis and integration of results was collected, which allowed the design of a useful, reliable and practical tool that helps complement and facilitate decision-making in favor of corporate well-being , economic, social and environmental for the municipalit

Diseño De Un Modelo De Balanced Scorecard Para La Optimización De Tiempo De Las Rutas De Transporte Público Urbano En Una Empresa Privada Del Municipio De Chía

Diseñar un modelo de gestión basado en la metodología del Balanced Scorecard (Cuadro de Mando Integral) para lograr la optimización en el tiempo de las rutas de transporte público urbano en una empresa del municipio de Chía.La planeación estratégica es uno de los pilares fundamentales dentro de la gestión empresarial que permite integrar las fortalezas con las oportunidades, analizando las debilidades y amenazas y direccionando correctamente el logro de los objetivos de la organización, generando a su vez, satisfacción a los usuarios internos y externos. Esta investigación diseña un modelo de gestión basado en la metodología del Balanced Scorecard (Cuadro de Mando Integral) para así lograr la optimización en el tiempo de las rutas de transporte público urbano en una empresa del municipio de Chía; este estudio tiene un enfoque de metodología mixta, cuenta con tres partes, la inicial de revisión documental, continuando así, con la segunda denominada trabajo de campo en la cual se aplicaron herramientas de diagnóstico como encuestas y entrevistas a la población objeto de este estudio, para concluir con la tercera fase donde se recopilo la información obtenida con el objeto de realizar el correspondiente análisis e integración de resultados, que permitieron el diseño de una herramienta útil, confiable y practica que ayude a complementar y facilitar la toma de decisiones en pro del bienestar empresarial, económico, social y medio ambiental para el municipio.Strategic planning is one of the fundamental pillars within business management that allows integrating strengths with opportunities by correctly directing the achievement of the organization's objectives, generating, in turn, satisfaction to internal and external users. This research aims to design a management model based on the Balanced Scorecard methodology to achieve optimization in time of urban public transport routes in a company in the municipality of Chia, in the light of social responsibility; This study has a mixed methodology approach, has three phases, the initial document review, continuing with the second phase of field work in which diagnostic tools such as surveys and interviews were applied to the population under study. , to conclude with the third phase where the information obtained to perform the corresponding analysis and integration of results was collected, which allowed the design of a useful, reliable and practical tool that helps complement and facilitate decision-making in favor of corporate well-being , economic, social and environmental for the municipalit

Insights in the Stock Mixing Dynamics of Atlantic Bluefin Tuna in the North Atlantic

Effective fisheries management requires accurate stock identification, which can be challenging in mixed stock fisheries such as the Atlantic bluefin tuna (Thunnus thynnus). This species is currently managed considering two stocks known to spawn in the Mediterranean Sea and Gulf of Mexico, respectively. However, recent studies have shown that individuals from both spawning components can interbreed at a recently discovered spawning ground, located in the Slope Sea. A better understanding of the mixing patterns, as well as the proportion in which both stocks interbreed in the Slope Sea are valuable for a reliable Atlantic bluefin tuna stock assessment. With this aim, we assigned genetic origin of 2000 individuals captured at feeding aggregates across the North Atlantic using a 96 SNP panel and analyzed the genetic profile of 500 individuals including 200 potential Slope Sea spawners (i.e., spawning capable individuals captured in this area at the spawning season), using a 8000 SNP array. We confirmed that stock mixing occurs across different feeding aggregates in the North Atlantic, being stronger in the Northwest Atlantic, where the Mediterranean component was a majority at some locations within and near the Slope Sea spawning ground. The analysis of Slope Sea spawner candidate individuals showed nearly equal representation from both Mediterranean and Gulf of Mexico genetic origin individuals, suggesting similar contribution to the Slope Sea origin offspring. Our findings constitute an important progress towards the understanding of the Atlantic bluefin tuna stock mixing dynamics and the relevance of the recently discovered Slope Sea spawning ground for the conservation of the species.En prens

The graphene oxide species induce a different biological response in SN4741 Parkinson cell line

Introduction: Graphene Oxide (GO)has recently emerged as a reliable material to create scaffolds for the neural tissue because of its biocompatibility, electroconductive and physicochemical properties. Graphene is a 2-dimensional material consisting of rings of carbon atoms with an excellent electrical conductivity originating in the sp2 hybridized carbons network. Nevertheless, there is not a consensus which kind of graphene oxide is most useful of benefit.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Attachment anxiety as mediator of the relationship between childhood trauma and personality dysfunction in borderline personality disorder

Insecure attachment has been described as mediating the relationship between childhood trauma and dysfunctional personality traits in different mental disorders. Despite the role insecure attachment and childhood trauma have independently demonstrated to play as determinants of borderline personality disorder, less is known about the mediating mechanisms explaining these associations. For the first time, we assessed adult attachment, childhood trauma and dimensional personality pathology in a sample of outpatients with borderline personality disorder and tested whether the association between childhood trauma and personality dysfunction was at least partially attributable to insecure attachment. The results showed that attachment anxiety fully mediated the relationship between specific types of trauma (emotional abuse and physical neglect) and emotional dysregulation. Further, emotional abuse was both directly associated with dissocial behaviour and indirectly via attachment anxiety (partial mediation). Emotional abuse has been described as an essential environmental factor for the development of borderline personality disorder and emotional dysregulation, on its part, as the core feature of the condition. Our results indicate that attachment anxiety explains the link between these central aspects of borderline personality disorder. Our findings are consistent with previous research and current etiological understanding of the condition and provide support for recommending a careful assessment of childhood traumatic experiences and adult attachment style to gain a more comprehensive insight into the symptoms and its heterogeneity. As a secondary aim, we assessed the effect parental mental illness may have in these mediation models, but no significant influence on childhood trauma, attachment or personality was found.This work was supported by the Health Department of the Basque Government under grant PI2014111034, by Biocruces Bizkaia Health Research Institute and by the Research Unit of Galdakao-Usansolo Hospital. Open access funding was provided by the University of the Basque Country UPV/EHU

Propuesta en Supply Chain Management y Logística en la empresa muebles Quintero Hermanos

Encuesta, gestión de inventarios, modos y medios de transporte, encuesta proceso de aprovisionamiento y matriz evaluación de proveedores.Se presenta una propuesta en Supply Chain Management y logística para la empresa Muebles Quintero Hermanos, dedicada a la producción y comercialización de muebles en madera para el hogar. Identificando los diferentes elementos que conforman el SCM y planteando estrategias de mejora para la gestión de la cadena de suministro en cada uno de sus componentes.A proposal in Supply Chain Management and logistics is presented for the company Muebles Quintero Hermanos, involved in the production and accessories of wooden furniture for the home. Identifying the different elements that make up the SCM and proposing improvement strategies for supply chain management in each of its component

Pandemic and post-pandemic Influenza A (H1N1) infection in critically ill patients

Background: There is a vast amount of information published regarding the impact of 2009 pandemic Influenza A (pH1N1) virus infection. However, a comparison of risk factors and outcome during the 2010-2011 post-pandemic period has not been described. Methods: A prospective, observational, multi-center study was carried out to evaluate the clinical characteristics and demographics of patients with positive RT-PCR for H1N1 admitted to 148 Spanish intensive care units (ICUs). Data were obtained from the 2009 pandemic and compared to the 2010-2011 post-pandemic period. Results: Nine hundred and ninety-seven patients with confirmed An/H1N1 infection were included. Six hundred and forty-eight patients affected by 2009 (pH1N1) virus infection and 349 patients affected by the post-pandemic Influenza (H1N1)v infection period were analyzed. Patients during the post-pandemic period were older, had more chronic comorbid conditions and presented with higher severity scores (Acute Physiology And Chronic Health Evaluation II (APACHE II) and Sequential Organ Failure Assessment (SOFA)) on ICU admission. Patients from the post-pandemic Influenza (H1N1)v infection period received empiric antiviral treatment less frequently and with delayed administration. Mortality was significantly higher in the post-pandemic period. Multivariate analysis confirmed that haematological disease, invasive mechanical ventilation and continuous renal replacement therapy were factors independently associated with worse outcome in the two periods. HIV was the only new variable independently associated with higher ICU mortality during the post-pandemic Influenza (H1N1)v infection period. Conclusion: Patients from the post-pandemic Influenza (H1N1)v infection period had an unexpectedly higher mortality rate and showed a trend towards affecting a more vulnerable population, in keeping with more typical seasonal viral infection

Nuclear astrophysics with radioactive ions at FAIR

R. Reifarth et al: ; 12 págs.; 9 figs.; Open Access funded by Creative Commons Atribution Licence 3.0 ; Nuclear Physics in Astrophysics VI (NPA6)The nucleosynthesis of elements beyond iron is dominated by neutron captures in the s and r processes. However, 32 stable, proton-rich isotopes cannot be formed during those processes, because they are shielded from the s-process ow and r-process -decay chains. These nuclei are attributed to the p and rp process. For all those processes, current research in nuclear astrophysics addresses the need for more precise reaction data involving radioactive isotopes. Depending on the particular reaction, direct or inverse kinematics, forward or time-reversed direction are investigated to determine or at least to constrain the desired reaction cross sections. The Facility for Antiproton and Ion Research (FAIR) will oer unique, unprecedented opportunities to investigate many of the important reactions. The high yield of radioactive isotopes, even far away from the valley of stability, allows the investigation of isotopes involved in processes as exotic as the r or rp processes.This project was supported by the HGF Young Investigators Project VH-NG-327, EMMI, H4F, HGS-HIRe, JINA, NAVI, DFG and ATHENA.Peer Reviewe

Risk factors for developing ventilator-associated lower respiratory tract infection in patients with severe COVID-19:a multinational, multicentre study, prospective, observational study

Around one-third of patients diagnosed with COVID-19 develop a severe illness that requires admission to the Intensive Care Unit (ICU). In clinical practice, clinicians have learned that patients admitted to the ICU due to severe COVID-19 frequently develop ventilator-associated lower respiratory tract infections (VA-LRTI). This study aims to describe the clinical characteristics, the factors associated with VA-LRTI, and its impact on clinical outcomes in patients with severe COVID-19. This was a multicentre, observational cohort study conducted in ten countries in Latin America and Europe. We included patients with confirmed rtPCR for SARS-CoV-2 requiring ICU admission and endotracheal intubation. Only patients with a microbiological and clinical diagnosis of VA-LRTI were included. Multivariate Logistic regression analyses and Random Forest were conducted to determine the risk factors for VA-LRTI and its clinical impact in patients with severe COVID-19. In our study cohort of 3287 patients, VA-LRTI was diagnosed in 28.8% [948/3287]. The cumulative incidence of ventilator-associated pneumonia (VAP) was 18.6% [610/3287], followed by ventilator-associated tracheobronchitis (VAT) 10.3% [338/3287]. A total of 1252 bacteria species were isolated. The most frequently isolated pathogens were Pseudomonas aeruginosa (21.2% [266/1252]), followed by Klebsiella pneumoniae (19.1% [239/1252]) and Staphylococcus aureus (15.5% [194/1,252]). The factors independently associated with the development of VA-LRTI were prolonged stay under invasive mechanical ventilation, AKI during ICU stay, and the number of comorbidities. Regarding the clinical impact of VA-LRTI, patients with VAP had an increased risk of hospital mortality (OR [95% CI] of 1.81 [1.40-2.34]), while VAT was not associated with increased hospital mortality (OR [95% CI] of 1.34 [0.98-1.83]). VA-LRTI, often with difficult-to-treat bacteria, is frequent in patients admitted to the ICU due to severe COVID-19 and is associated with worse clinical outcomes, including higher mortality. Identifying risk factors for VA-LRTI might allow the early patient diagnosis to improve clinical outcomes. Trial registration: This is a prospective observational study; therefore, no health care interventions were applied to participants, and trial registration is not applicable