293 research outputs found

    Body Fixed Frame, Rigid Gauge Rotations and Large N Random Fields in QCD

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    The "body fixed frame" with respect to local gauge transformations is introduced. Rigid gauge "rotations" in QCD and their \Sch equation are studied for static and dynamic quarks. Possible choices of the rigid gauge field configuration corresponding to a nonvanishing static colormagnetic field in the "body fixed" frame are discussed. A gauge invariant variational equation is derived in this frame. For large number N of colors the rigid gauge field configuration is regarded as random with maximally random probability distribution under constraints on macroscopic--like quantities. For the uniform magnetic field the joint probability distribution of the field components is determined by maximizing the appropriate entropy under the area law constraint for the Wilson loop. In the quark sector the gauge invariance requires the rigid gauge field configuration to appear not only as a background but also as inducing an instantaneous quark-quark interaction. Both are random in the large N limit.Comment: 29 pages LATEX, Weizmann Institute preprint WIS-93/40/Apr -P

    Can additive beta-diversity be reliably partitioned into nestedness and turnover components?

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    Aims: Quantifying ÎČ‐diversity (differences in the composition of communities) is central to many ecological studies. There are many ÎČ‐diversity metrics, falling mostly into two approaches: variance‐based (e.g., the SĂžrensen index), or diversity partitioning (e.g., additive ÎČ‐diversity). The former cannot be used when species–sites matrices are unavailable (which is often the case in island biogeography in particular) and only species richness data are provided. Recently, efforts have been made to partition additive ÎČ‐diversity, a metric calculated using only α‐diversity and γ‐diversity, into nestedness and turnover components (termed here “richness‐only ÎČ‐diversity partitioning”). We set out to test whether this form of ÎČ‐diversity partitioning generates interpretable results, comparable with metrics based on species incidence ÎČ‐diversity partitioning. Location: Global. Time period: Present day. Major taxa studied: Multiple taxa. Methods: We first provide a brief review of ÎČ‐diversity partitioning methods, with a particular focus on the development of richness‐only ÎČ‐diversity partitioning. Second, we use 254 empirical incidence matrices (provided with the paper) sourced from the literature to measure turnover and nestedness using incidence ÎČ‐diversity partitioning, comparing the resulting values with those calculated using richness‐only ÎČ‐diversity. Results: We provide an account of the emergence of ÎČ‐diversity partitioning, with particular reference to the analysis of richness‐only datasets, and to the definition and usage of the relevant metrics. Analytically, we report weak correlations between turnover and nestedness calculated using the two different approaches. We show that this is because identical values of α‐diversity and γ‐diversity can correspond to incidence matrices with a range of different structures. Main conclusions: Our results demonstrate that the use of richness‐only ÎČ‐diversity partitioning to measure turnover and nestedness is problematic and can produce patterns unrelated to conventional measures of turnover and nestedness. We therefore recommend that more accurate definitions are adopted for these terms in future studies.</br

    State-building, war and violence : evidence from Latin America

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    In European history, war has played a major role in state‐building and the state monopoly on violence. But war is a very specific form of organized political violence, and it is decreasing on a global scale. Other patterns of armed violence now dominate, ones that seem to undermine state‐building, thus preventing the replication of European experiences. As a consequence, the main focus of the current state‐building debate is on fragility and a lack of violence control inside these states. Evidence from Latin American history shows that the specific patterns of the termination of both war and violence are more important than the specific patterns of their organization. Hence these patterns can be conceptualized as a critical juncture for state‐building. While military victories in war, the subordination of competing armed actors and the prosecution of perpetrators are conducive for state‐building, negotiated settlements, coexistence, and impunity produce instability due to competing patterns of authority, legitimacy, and social cohesion

    A intricada leitura de literatura - um novo processo socioeducacional de conhecimento

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    Frente aos desafios educacionais neoliberais p&#243;s-modernos, &#224; escola brasileira &#8211; e &#224; pr&#225;tica / ensino de leitura tamb&#233;m liter&#225;ria &#8211; cumpre-se o objetivo de reconstruir o novo sobre as marcas de uma rela&#231;&#227;o pedag&#243;gica professor-aluno rotineiramente desgastada. Nesse ambiente, surgem quest&#245;es como o que se pretende lendo aleatoriamente textos na escola? Para onde leva essa leitura? Quem somos, quando se l&#234;? Por que nos transformamos nessas ciberm&#225;quinas de passividade metodol&#243;gica? Nossos alunos est&#227;o sendo orientados, previamente, a leituras de determinados autores can&#244;nicos, e n&#227;o can&#244;nicos, sabendo o motivo de tal leitura aplicada a sua realidade de leitor? E "ler" literatura &#233; algo que se ensine? Pode-se ensinar algu&#233;m a ler entendendo a leitura como fonte dupla de informa&#231;&#227;o e prazer? N&#227;o h&#225; mais como imaginar uma escola perif&#233;rica, &#225;s margens dos acontecimentos di&#225;rios e, assim, ou essa nossa nova escola &#8211; professores, alunos, agentes administrativos &#8211; se adapta produtivamente a essa realidade contempor&#226;nea ou estar&#225; fadada a perder o rumo da hist&#243;ria nacional, regional e mundial. Adapta&#231;&#227;o produtiva, no sentido de renovar a cr&#237;tica aos costumes, aos valores, aos preconceitos. Os dados que complementam tais quest&#245;es te&#243;ricas resultam de pesquisa desenvolvida com alunos do ensino m&#233;dio, de uma escola p&#250;blica de S&#227;o Paulo-Brasil, com o objetivo de avaliar, em sala de aula, pr&#225;ticas de uma leitura produtiva com foco no papel do que aqui se considera como leitor-real

    Detection of Mitochondrial COII DNA Sequences in Ant Guts as a Method for Assessing Termite Predation by Ants

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    Termites and ants contribute more to animal biomass in tropical rain forests than any other single group and perform vital ecosystem functions. Although ants prey on termites, at the community level the linkage between these groups is poorly understood. Thus, assessing the distribution and specificity of ant termitophagy is of considerable interest.We describe an approach for quantifying ant-termite food webs by sequencing termite DNA (cytochrome c oxidase subunit II, COII) from ant guts and apply this to a soil-dwelling ant community from tropical rain forest in Gabon. We extracted DNA from 215 ants from 15 species. Of these, 17.2% of individuals had termite DNA in their guts, with BLAST analysis confirming the identity of 34.1% of these termites to family level or better. Although ant species varied in detection of termite DNA, ranging from 63% (5/7; Camponotus sp. 1) to 0% (0/7; Ponera sp. 1), there was no evidence (with small sample sizes) for heterogeneity in termite consumption across ant taxa, and no evidence for species-specific ant-termite predation. In all three ant species with identifiable termite DNA in multiple individuals, multiple termite species were represented. Furthermore, the two termite species that were detected on multiple occasions in ant guts were in both cases found in multiple ant species, suggesting that anttermite food webs are not strongly compartmentalised. However, two ant species were found to consume only Anoplotermes-group termites, indicating possible predatory specialisation at a higher taxonomic level. Using a laboratory feeding test, we were able to detect termite COII sequences in ant guts up to 2 h after feeding, indicating that our method only detects recent feeding events. Our data provide tentative support for the hypothesis that unspecialised termite predation by ants is widespread and highlight the use of molecular approaches for future studies of ant-termite food webs

    Transcriptome analyses based on genetic screens for Pax3 myogenic targets in the mouse embryo

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    <p>Abstract</p> <p>Background</p> <p>Pax3 is a key upstream regulator of the onset of myogenesis, controlling progenitor cell survival and behaviour as well as entry into the myogenic programme. It functions in the dermomyotome of the somite from which skeletal muscle derives and in progenitor cell populations that migrate from the somite such as those of the limbs. Few Pax3 target genes have been identified. Identifying genes that lie genetically downstream of <it>Pax3 </it>is therefore an important endeavour in elucidating the myogenic gene regulatory network.</p> <p>Results</p> <p>We have undertaken a screen in the mouse embryo which employs a <it>Pax3<sup>GFP </sup></it>allele that permits isolation of Pax3 expressing cells by flow cytometry and a <it>Pax3<sup>PAX3-FKHR </sup></it>allele that encodes PAX3-FKHR in which the DNA binding domain of Pax3 is fused to the strong transcriptional activation domain of FKHR. This constitutes a gain of function allele that rescues the <it>Pax3 </it>mutant phenotype. Microarray comparisons were carried out between <it>Pax3<sup>GFP/+ </sup></it>and <it>Pax3<sup>GFP/PAX3-FKHR </sup></it>preparations from the hypaxial dermomyotome of somites at E9.5 and forelimb buds at E10.5. A further transcriptome comparison between Pax3-GFP positive and negative cells identified sequences specific to myogenic progenitors in the forelimb buds. Potential Pax3 targets, based on changes in transcript levels on the gain of function genetic background, were validated by analysis on loss or partial loss of function <it>Pax3 </it>mutant backgrounds. Sequences that are up- or down-regulated in the presence of PAX3-FKHR are classified as somite only, somite and limb or limb only. The latter should not contain sequences from Pax3 positive neural crest cells which do not invade the limbs. Verification by whole mount <it>in situ </it>hybridisation distinguishes myogenic markers. Presentation of potential Pax3 target genes focuses on signalling pathways and on transcriptional regulation.</p> <p>Conclusions</p> <p>Pax3 orchestrates many of the signalling pathways implicated in the activation or repression of myogenesis by regulating effectors and also, notably, inhibitors of these pathways. Important transcriptional regulators of myogenesis are candidate Pax3 targets. Myogenic determination genes, such as <it>Myf5 </it>are controlled positively, whereas the effect of <it>Pax3 </it>on genes encoding inhibitors of myogenesis provides a potential brake on differentiation. In the progenitor cell population, <it>Pax7 </it>and also <it>Hdac5 </it>which is a potential repressor of <it>Foxc2</it>, are subject to positive control by <it>Pax3</it>.</p

    Imaging findings in craniofacial childhood rhabdomyosarcoma

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    Rhabdomyosarcoma (RMS) is the commonest paediatric soft-tissue sarcoma constituting 3–5% of all malignancies in childhood. RMS has a predilection for the head and neck area and tumours in this location account for 40% of all childhood RMS cases. In this review we address the clinical and imaging presentations of craniofacial RMS, discuss the most appropriate imaging techniques, present characteristic imaging features and offer an overview of differential diagnostic considerations. Post-treatment changes will be briefly addressed

    Identifying Where REDD+ Financially Out Competes Oil Palm in Floodplain Landscapes Using a Fine-Scale Approach

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    Reducing Emissions from Deforestation and forest Degradation (REDD+) aims to avoid forest conversion to alternative land-uses through financial incentives. Oil-palm has high opportunity costs, which according to current literature questions the financial competitiveness of REDD+ in tropical lowlands. To understand this more, we undertook regional finescale and coarse-scale analyses (through carbon mapping and economic modelling) to assess the financial viability of REDD+ in safeguarding unprotected forest (30,173 ha) in the Lower Kinabatangan floodplain in Malaysian Borneo. Results estimate 4.7 million metric tons of carbon (MgC) in unprotected forest, with 64% allocated for oil-palm cultivations. Through fine-scale mapping and carbon accounting, we demonstrated that REDD+ can outcompete oil-palm in regions with low suitability, with low carbon prices and low carbon stock. In areas with medium oil-palm suitability, REDD+ could outcompete oil palm in areas with: very high carbon and lower carbon price; medium carbon price and average carbon stock; or, low carbon stock and high carbon price. Areas with high oil palm suitability, REDD + could only outcompete with higher carbon price and higher carbon stock. In the coarse-scale model, oil-palm outcompeted REDD+ in all cases. For the fine-scale models at the landscape level, low carbon offset prices (US 3MgCO2e)wouldenableREDD+tooutcompeteoil−palmin553 MgCO2e) would enable REDD+ to outcompete oil-palm in 55% of the unprotected forests requiring US 27 million to secure these areas for 25 years. Higher carbon offset price (US 30MgCO2e)wouldincreasethecompetitivenessofREDD+withinthelandscapebutwouldstillonlycapturebetween6930 MgCO2e) would increase the competitiveness of REDD+ within the landscape but would still only capture between 69%-74% of the unprotected forest, requiring US 380–416 million in carbon financing. REDD+ has been identified as a strategy to mitigate climate change by many countries (including Malaysia). Although REDD+ in certain scenarios cannot outcompete oil palm, this research contributes to the global REDD+ debate by: highlighting REDD+ competitiveness in tropical floodplain landscapes; and, providing a robust approach for identifying and targeting limited REDD+ funds
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