877 research outputs found

    Study of Beauty Hadron Decays into Pairs of Charm Hadrons

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    First observations of the decays Λ[0 over b] → Λ[+ over c]D[− over (s)] are reported using data corresponding to an integrated luminosity of 3  fb[superscript −1] collected at 7 and 8 TeV center-of-mass energies in proton-proton collisions with the LHCb detector. In addition, the most precise measurement of the branching fraction B(B[0 over s] → D[superscript +]D[− over s]) is made and a search is performed for the decays B[0 over (s)] → Λ[+ over c]Λ[− over c]. The results obtained are B(Λ[0 over b] → Λ[+ over c]D[superscript −])/B(Λ[0 over b] → Λ[+ over c]D[− over s]) = 0.042 ± 0.003(stat) ± 0.003(syst), ⎡⎣B(Λ[0 over b] → Λ[+ over c]D[− over s]) over B([¯ over B[superscript 0] → D[superscript +]D[− over s])⎤⎦/⎡⎣B(Λ[0 over b] → Λ[+ over c]π[superscript −]) over B([¯ over B[superscript 0] → D[superscript +]π[superscript −])⎤⎦ = 0.96 ± 0.02(stat) ± 0.06(syst), B(B[0 over s] → D[superscript +]D[− over s])/B([¯ over B][superscript 0] → D[superscript +]D[− over s]) = 0.038 ± 0.004(stat) ± 0.003(syst), B([¯ over B][superscript 0] → Λ[+ over c]Λ[− over c])/B([¯ over B][superscript 0] → D[superscript +]D[− over s]) < 0.0022[95%  C.L.], B(B[0 over s] → Λ[+ over c]Λ[− over c])/B(B[0 over s] → D[superscript +]D[− over s]) < 0.30[95%  C.L.]. Measurement of the mass of the Λ[0 over b] baryon relative to the [¯ over B][superscript 0] meson gives M(Λ[0 over b]) − M([¯ over B][superscript 0]) = 339.72 ± 0.24(stat) ± 0.18(syst)  MeV/c[superscript 2]. This result provides the most precise measurement of the mass of the Λ[0 over b] baryon to date.National Science Foundation (U.S.

    The effectiveness of an intensive individual tutoring programme (Numbers Count) delivered individually or to small groups of children: a randomised controlled trial

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    Introduction: In this article, we present the results of two small randomised controlled trials (RCTs) investigating the relative efficacy of a one-to-one numeracy programme, Numbers Count (NC). This intervention was developed as part of the Every Child Counts programme to specifically target the lowest achieving children at key stage 1 (KS1) mathematics. The research question focused on the relative efficacy of NC delivered either individually (as originally intended by the developers of the programme) or in an adapted version to small groups of two or three children. Design and methods: In 15 schools 75 children in year 2 identified by the schools as being eligible to receive NC were randomised to receive it individually or in pairs and in 7 schools 54 children in year 2 identified by the schools as being eligible to receive NC were randomised to receive it individually or in triplets during the school year 2009–2010. The design of the trial required five children, for the pairs sub-trial, or seven children for the triplets sub-trial in each school to receive NC individually or in pairs/triplets in autumn term 2009 or spring term 2010. Results: The primary outcome measure Progress in Maths 6 (PIM 6) was undertaken and marked blind to group allocation by independent testers. We found no statistically significant difference between the scores of the children taught individually or in pairs in terms of PIM 6 scores although a slight difference in favour of pairs was observed. We also found no statistically significant differences between children taught individually or in triplets in terms of PIM 6 scores. We pooled the effect sizes for individual versus pairs and triplets delivery in a meta-analysis of individual versus small group teaching. The pooled effect size was −.26 (CI −2.18 to 1.65) which demonstrates no statistically significant difference between individual and small group teaching. Conclusion: There was no evidence of a difference between the groups, which was not unexpected as our sample sizes were relatively small. This is the only robust evidence from RCTs of the promise of the intervention. However, given the small sample sizes of the trials, we recommend further larger trials should be undertaken comparing small group mathematics teaching with one-to-one educational interventions, using both this programme and others. These two trials could also usefully be included in meta-analyses comparing small group and one-to-one teaching in mathematics education

    The Mississippian Section at Paddys Bluff, Crittenden County, Kentucky

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    Paddys Bluff (Figs. 1-3) is located on the south side of the Illinois Basin on the Cumberland River, 1.7 miles downstream from Dycusburg in Crittenden County, Ky., in Carter coordinate section 23-I-16 and ecoregion 71f of the Western Highland Rim of Kentucky (Woods and others, 2002). This bluff is on a right-descending bend 18 liver miles above its junction with the Ohio River at Smithland, Livingston County. The bluff (Figs. 4A, B) is locally famous as the location for a scene from the classic 1962 film, How the West Was Won,\u27 a winner of three Academy Awards, starling James Stewart, John Wayne, and others. We observed Paddys Bluff from the starboard Texas deck of the steamboat Della Queen one rainy morning in October 2005; the thick, persistent white bed midway in the bluff especially attracted our attention (Fig. 4). Paddys Bluff is the best natural exposure of Mississippian limestone between Barkley Dam and the Ohio River, a distance of 31 river miles. The bluff, some 1,700 feet long (Fig. 4), rises 160 feet above the Cumberland River and deflects it about 16° into a long westward reach, the river removing all talus at the base of the bluff. The bluff lies in a graben between two inferred faults st liking N40 to 45°E (Amos and Hayes, 1974). Readily seen in the limestones along the river at the base of the bluff is a prominent joint set parallel to these faults. This bluff is mapped on the Dycusburg geologic quadrangle map (Table 1) as the combined Salem and St. Louis Limestones (Amos and Hayes, 1974) and is capped by at least 15 feet of poorly exposed gravel of the Cretaceous Tuscaloosa Formation (Olive, 1980). Across the river less than 2 miles distant are scattered continental deposits of reddish brown Lafayette-type, sandy cobble-gravel (Olive, 1980), below which are outliers of the Cretaceous Tuscaloosa Formation; both cap hilltops of the same underlying Mississippian limestones. Why is Paddys Bluff of interest? There are at least six reasons to study it. First, can the Salem and St. Louis Limestones be individually identified at the bluff? If, in fact, they can be separated, the upper boundary of sequence S4 recognized in the Lake Cumberland area of south-central Kentucky by Khetani and Read (2002, Fig. 12) extends much farther west. Still another challenge is the enigmatic, massive, fine-grained, whitish-weathering carbonate mudstone bed, unit C of our section, high in the bluff. What does it represent? How widespread is it? Why do beds below rt have a strong petroliferous odor and not those above it? Why are some of the coral heads (Fig. 5) at Paddys Bluff overturned and others not? The last challenge is the bluff itself: Why is it there and how long has it been there

    Amelioration of bleomycin-induced lung fibrosis in hamsters by dietary supplementation with taurine and niacin: biochemical mechanisms.

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    Interstitial pulmonary fibrosis induced by intratracheal instillation of bleomycin (BL) involves an excess production of reactive oxygen species, unavailability of adequate levels of NAD and ATP to repair the injured pulmonary epithelium, and an overexuberant lung collagen reactivity followed by deposition of highly cross-linked mature collagen fibrils resistant to enzymatic degradation. In the present study, we have demonstrated that dietary supplementation with taurine and niacin offered almost complete protection against the lung fibrosis in a multidose BL hamster model. The mechanisms for the protective effect of taurine and niacin are multifaceted. These include the ability of taurine to scavenge HOCl and stabilize the biomembrane; niacin's ability to replenish the BL-induced depletion of NAD and ATP; and the combined effect of taurine and niacin to suppress all aspects of BL-induced increases in the lung collagen reactivity, a hallmark of interstitial pulmonary fibrosis. It was concluded from the data presented at this Conference that the combined treatment with taurine and niacin, which offers a multipronged approach, will have great therapeutic potential in the intervention of the development of chemically induced interstitial lung fibrosis in animals and humans

    The global macroeconomic burden of Alzheimer's disease and other dementias: estimates and projections for 152 countries or territories

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    Background: Alzheimer's disease and other dementias (ADODs) severely threaten the wellbeing of older people, their families, and communities, especially with projected exponential growth. Understanding the macroeconomic implications of ADODs for policy making is essential but under-researched. Methods: We used a health-augmented macroeconomic model to calculate the macroeconomic burden of ADODs for 152 countries or territories, accounting for: the effect on labour supply of reduced working hours of informal caregivers; the effect on labour supply of ADODs-related mortality and morbidity; age-sex-specific differences in education, work experience, labour market participations, and informal caregivers; and treatment and formal care costs diverting from savings and investments. Findings: ADODs will cost the world economy 14 513 billion international dollars (INT,measuredinthebaseyear2020;95, measured in the base year 2020; 95% uncertainty interval [UI] 12 106-17 778) from 2020 to 2050, equivalent to 0·421% (95% UI 0·351-0·515) of annual global GDP. Japan incurs the largest annual GDP loss at 1·463% (1·225-1·790). China (INT2961 billion [2507-3564]), the USA (INT2331billion[19892829]),andJapan(INT2331 billion [1989-2829]), and Japan (INT1758 billion [1471-2150]) face the largest absolute economic burdens. The economic burden of informal care ranges from 60·97% in high-income countries to 85·45% in lower-middle-income countries, and treatment and formal care costs range from 10·50% in lower-middle-income countries to 30·80% in high-income countries. Interpretation: The macroeconomic burden of ADODs is substantial and unequally distributed across countries and regions. Global efforts to reduce the burden, especially with regard to informal care, are urgently needed

    Observation of associated production of a ZZ boson with a DD meson in the~forward region

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    A search for associated production of a ZZ boson with an open charm meson is presented using a data sample, corresponding to an integrated luminosity of 1.0fb1.0\,\mathrm{fb}^{-`} of proton--proton collisions at a centre-of-mass energy of 7\,TeV, collected by the LHCb experiment. %% Seven candidate events for associated production of a ZZ boson with a D0D^0 meson and four candidate events for a ZZ boson with a D+D^+ meson are observed with a combined significance of 5.1standard deviations. The production cross-sections in the forward region are measured to be σZμ+μ ⁣,D0=2.50±1.12±0.22pb\sigma_{Z\rightarrow\mu^+\mu^-\!,D^0} = 2.50\pm1.12\pm0.22pb σZμ+μ ⁣,D+=0.44±0.23±0.03pb,\sigma_{Z\rightarrow\mu^+\mu^-\!,D^+} = 0.44\pm0.23\pm0.03pb, where the first uncertainty is statistical and the second systematic.Comment: 18 pages, 2 figure

    Observation of two new Ξb\Xi_b^- baryon resonances

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    Two structures are observed close to the kinematic threshold in the Ξb0π\Xi_b^0 \pi^- mass spectrum in a sample of proton-proton collision data, corresponding to an integrated luminosity of 3.0 fb1^{-1} recorded by the LHCb experiment. In the quark model, two baryonic resonances with quark content bdsbds are expected in this mass region: the spin-parity JP=12+J^P = \frac{1}{2}^+ and JP=32+J^P=\frac{3}{2}^+ states, denoted Ξb\Xi_b^{\prime -} and Ξb\Xi_b^{*-}. Interpreting the structures as these resonances, we measure the mass differences and the width of the heavier state to be m(Ξb)m(Ξb0)m(π)=3.653±0.018±0.006m(\Xi_b^{\prime -}) - m(\Xi_b^0) - m(\pi^{-}) = 3.653 \pm 0.018 \pm 0.006 MeV/c2/c^2, m(Ξb)m(Ξb0)m(π)=23.96±0.12±0.06m(\Xi_b^{*-}) - m(\Xi_b^0) - m(\pi^{-}) = 23.96 \pm 0.12 \pm 0.06 MeV/c2/c^2, Γ(Ξb)=1.65±0.31±0.10\Gamma(\Xi_b^{*-}) = 1.65 \pm 0.31 \pm 0.10 MeV, where the first and second uncertainties are statistical and systematic, respectively. The width of the lighter state is consistent with zero, and we place an upper limit of Γ(Ξb)<0.08\Gamma(\Xi_b^{\prime -}) < 0.08 MeV at 95% confidence level. Relative production rates of these states are also reported.Comment: 17 pages, 2 figure

    Measurements of the B+B^+, B0B^0, Bs0B_s^0 meson and Λb0\Lambda_b^0 baryon lifetimes

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    Measurements of bb-hadron lifetimes are reported using pppp collision data, corresponding to an integrated luminosity of 1.0fb1^{-1}, collected by the LHCb detector at a centre-of-mass energy of 77Tev. Using the exclusive decays B+J/ψK+B^+\to J/\psi K^+, B0J/ψK(892)0B^0\to J/\psi K^*(892)^0, B0J/ψKS0B^0\to J/\psi K^0_{\rm S}, Λb0J/ψΛ\Lambda_b^0\to J/\psi \Lambda and Bs0J/ψϕB^0_s\to J/\psi \phi the average decay times in these modes are measured to be τB+J/ψK+\tau_{B^+\to J/\psi K^+} = 1.637±1.637 \pm 0.004 ±\pm 0.003 ps, τB0J/ψK(892)0\tau_{B^0\to J/\psi K^*(892)^0} = 1.524±1.524 \pm 0.006 ±\pm 0.004 ps, τB0J/ψKS0\tau_{B^0\to J/\psi K^0_{\rm S}} = 1.499±1.499 \pm 0.013 ±\pm 0.005 ps, τΛb0J/ψΛ\tau_{\Lambda_b^0\to J/\psi \Lambda} = 1.415±1.415 \pm 0.027 ±\pm 0.006 ps and τBs0J/ψϕ\tau_{B^0_s\to J/\psi \phi} = 1.480±1.480 \pm 0.011 ±\pm 0.005 ps, where the first uncertainty is statistical and the second is systematic. These represent the most precise lifetime measurements in these decay modes. In addition, ratios of these lifetimes, and the ratio of the decay-width difference, ΔΓd\Delta\Gamma_d, to the average width, Γd\Gamma_d, in the B0B^0 system, ΔΓd/Γd=0.044±0.025±0.011\Delta \Gamma_d/\Gamma_d = -0.044 \pm 0.025 \pm 0.011, are reported. All quantities are found to be consistent with Standard Model expectations.Comment: 28 pages, 4 figures. Updated reference
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