Proton-pump inhibitors prescription in a tertiary teaching hospital internal medicine ward

Trabalho Final do Curso de Mestrado Integrado em Medicina, Faculdade de Medicina, Universidade de Lisboa, 2017Introduction: Proton-Pump Inhibitors (PPI) are a class of drugs widely used to suppress acid production by the gastrointestinal system. Although in recent years several guidelines on PPI usage have been released, suggesting finite periods of treatment for most cases, there has been a growing rate of the amount of PPI prescription, some with no clear indication. A lack of perception of PPI’s side effects may also lead to a global overprescription of this drug class. Materials and Methods: We conducted a retrospective and descriptive study of the discharge notes of an Internal Medicine ward. The following data was gathered: inpatient identification number, age and sex, admission and discharge information (whether the patient was on PPI and which PPI; whether there was a formal indication for such prescription explicit on the discharge note and which) and data concerning adverse effects. Results: In a total of 542 patients, 47,2% were on PPI at admission and 55,4% were prescribed PPI at discharge. 48,4% at admission and 49% at discharge were on medication that could cause dyspeptic symptoms; 33,2% at admission and 28,3% at discharge had no explicit diagnose or medication that justified PPI prescription; only 8,6% at admission and 10,7% at discharge had a written diagnosis for such prescription. Conclusions: These results suggest a great volume of PPI prescription in patients admitted at the studied hospital, increasing at discharge. Except when there is a clear gastrointestinal disease, most discharge notes lack justification for PPI prescription. International guidelines point towards finite PPI treatment periods for most cases, but in no discharge note was such period defined.Introdução: Os Inibidores da Bomba de Protões (IBP) são uma classe de fármacos utilizada para suprimir a produção ácida pelo sistema gastrointestinal. Apesar de recentemente várias recomendações para correta prescrição de IBP terem sido lançadas, estabelecendo para a maioria dos casos períodos finitos de tratamento, verifica-se uma taxa crescente da sua prescrição. A falta de perceção dos efeitos adversos dos IBP poderá também contribuir para este problema. Materiais e Métodos: Conduzimos um estudo retrospetivo e descritivo das notas de alta de uma enfermaria de medicina interna, recolhendo os seguintes dados dos doentes: identificação, sexo e idade, informação à data de entrada e alta (se medicado com IBP e qual IBP; presença de indicação formal para a sua prescrição e qual), bem como informação sobre efeitos adversos dos IBP. Resultados: Num total de 542 doentes, 47,2% estava medicado com IBP à entrada e a 55,4% foram-no à data de alta. 48,4% à entrada e 49% à alta estavam medicados com fármacos passíveis de causar dispepsia; 33,2% à entrada e 28,3% à alta não apresentavam diagnóstico ou medicação que justificasse prescrição de IBP; apenas 8,6% à entrada e 10,7% à alta apresentavam um diagnóstico explícito que justifica prescrição de IBP. Conclusões: Os resultados apontam para um elevado volume de prescrição de IBP em ambulatório, que aumenta à data da alta. Exceto na presença clara de patologia gastrointestinal, à maior parte das notas de alta falta justificação explícita para prescrição de IBP. Apesar da maioria das Guidelines internacionais apontar para um período finito de tratamento em grande parte dos casos, em nenhuma nota de alta foi explícito um prazo de tratamento com IBP

Impact of personality traits on prosthodontic patients

Determining oral health-related quality of life in elderly patients with removable prostheses who have increased difficulty in reporting oral issues is imperative for a successful rehabilitation. Aim: Our objective is to assess the extent to which a trace, or personality dimension, can influence oral health-related quality of life (OHRQoL) in rehabilitated patients. Methods: 135 participants rehabilitated with removable prosthesis were evaluated in the Clinical Unit of Removable Prosthodontics of the Faculty of Dental Medicine of Porto University, Portugal. The Oral Health Impact Profile (OHIP-14) questionnaire was applied to evaluate oral health-related quality of life, along with the Eysenck Personality Inventory (E.P.I.) to determine a personality trait. Statistical analysis was carried out using Mann-Whitney, Student's t-test, Spearman's rho and linear regression. Results: No statistical correlation was found concerning age, gender and oral health-related quality of life. Regarding the latter, the highest agreement was found on the question involving “pain in teeth”. The prevalence of acrylic partial dentures, as opposed to partial dentures with metallic framework, was substantially higher. No signi?cant association between both extraversion/neuroticism (E.P.I.) and oral health-related quality of life (OHIP-14) upon rehabilitation with removable prostheses was found (p>0,05). In our study, personality traits neuroticism and extraversion did not influence oral health-related quality of life with removable prostheses. However, we should not overlook the importance of other psychological factors (such as motivation or perception) and their role in determining oral health-related quality of life. Conclusion: Personality traits “extraversion” and “neuroticism” did not influence oral health-related quality of life.info:eu-repo/semantics/publishedVersio

APICULTURA E RESPONSABILIDADE SOCIAL: DESAFIOS DA PRODUÇÃO E DIFICULDADES EM ADOTAR PRÁTICAS SOCIAL E AMBIENTALMENTE RESPONSÁVEIS

RESUMOO artigo objetiva identificar a percepção e as dificuldades que os produtores têm em adotar práticas mais responsáveis social e ambientalmente. Utilizou-se de método qualitativo, com entrevista semiestruturada com cinco das seis pessoas que participam da Associação de Apicultores. Nesse sentido, a pesquisa utilizou a análise categorial temática, com o desmembramento em categorias conforme os temas que emergem do texto identificando o que eles têm em comum, dividida em quatro categorias temáticas: 3.1 - Perfil dos entrevistados; 3.2 - Determinação da criação de abelhas e da produção do mel; 3.3 - Conhecimento da atividade e importância da associação; 3.4 - Comercialização e responsabilidade social e ambiental. A responsabilidade social em relação ao mel foi evidenciada como um diferencial no produto concentrado nas preocupações com o meio ambiente, influenciando as tomadas de decisões dos apicultores em seus negócios, bem como no comprometimento para a melhoria da qualidade de vida e bem-estar social. Os resultados da pesquisa também demonstraram que a apicultura é uma atividade lucrativa. No entanto, se percebeu que, em decorrência dos associados não estarem bem organizados, têm dificuldades em comercializar seus produtos

2 nd Brazilian Consensus on Chagas Disease, 2015

Abstract Chagas disease is a neglected chronic condition with a high burden of morbidity and mortality. It has considerable psychological, social, and economic impacts. The disease represents a significant public health issue in Brazil, with different regional patterns. This document presents the evidence that resulted in the Brazilian Consensus on Chagas Disease. The objective was to review and standardize strategies for diagnosis, treatment, prevention, and control of Chagas disease in the country, based on the available scientific evidence. The consensus is based on the articulation and strategic contribution of renowned Brazilian experts with knowledge and experience on various aspects of the disease. It is the result of a close collaboration between the Brazilian Society of Tropical Medicine and the Ministry of Health. It is hoped that this document will strengthen the development of integrated actions against Chagas disease in the country, focusing on epidemiology, management, comprehensive care (including families and communities), communication, information, education, and research

Catálogo Taxonômico da Fauna do Brasil: setting the baseline knowledge on the animal diversity in Brazil

The limited temporal completeness and taxonomic accuracy of species lists, made available in a traditional manner in scientific publications, has always represented a problem. These lists are invariably limited to a few taxonomic groups and do not represent up-to-date knowledge of all species and classifications. In this context, the Brazilian megadiverse fauna is no exception, and the Catálogo Taxonômico da Fauna do Brasil (CTFB) (http://fauna.jbrj.gov.br/), made public in 2015, represents a database on biodiversity anchored on a list of valid and expertly recognized scientific names of animals in Brazil. The CTFB is updated in near real time by a team of more than 800 specialists. By January 1, 2024, the CTFB compiled 133,691 nominal species, with 125,138 that were considered valid. Most of the valid species were arthropods (82.3%, with more than 102,000 species) and chordates (7.69%, with over 11,000 species). These taxa were followed by a cluster composed of Mollusca (3,567 species), Platyhelminthes (2,292 species), Annelida (1,833 species), and Nematoda (1,447 species). All remaining groups had less than 1,000 species reported in Brazil, with Cnidaria (831 species), Porifera (628 species), Rotifera (606 species), and Bryozoa (520 species) representing those with more than 500 species. Analysis of the CTFB database can facilitate and direct efforts towards the discovery of new species in Brazil, but it is also fundamental in providing the best available list of valid nominal species to users, including those in science, health, conservation efforts, and any initiative involving animals. The importance of the CTFB is evidenced by the elevated number of citations in the scientific literature in diverse areas of biology, law, anthropology, education, forensic science, and veterinary science, among others

Antologia pombalina

Antologia de poemas (1759-1905)

Approaches to youth worlds : ibero-American dialogues

La colección Jóvenes con dis…cursos, impulsada por el Observatorio Javeriano de Juventud, es un instrumento de difusión del conocimiento producido en el campo de la juventud en Colombia. Se nutre de alianzas académicas y encuentros diversos entre investigadores en juventud, tanto de Colombia como de otros países de Iberoamérica. Las/los investigadores aquí reunidos aportan sus resultados investigativos y sus reflexiones al debate sobre las juventudes y su presente y futuro. Su nombre alude, mediante un juego de palabras, a la puesta en común de distintos saberes, ejes temáticos y perspectivas de análisis, para evidenciar condiciones y contextos que generan realidades, problemas y salidas creativas a los avatares de la vida juvenil contemporánea.Bogot