2,162 research outputs found
Clergy work-related satisfactions in parochial ministry: the influence of personality and churchmanship
The aim of this study was to test several hypotheses that clergy work-related satisfaction could be better explained by a multidimensional rather than a unidimensional model. A sample of 1071 male stipendiary parochial clergy in the Church of England completed the Clergy Role Inventory, together with the short-form Revised Eysenck Personality Questionnaire. Factor analysis of the Clergy Role Inventory identified five separate clergy roles: Religious Instruction, Administration, Statutory Duties (conducting marriages and funerals), Pastoral Care, and Role Extension (including extra-parochial activities). Respondents also provided an indication of their predispositions on the catholic-evangelical and liberal-conservative dimensions. The significant associations of the satisfactions derived from each of the roles with the demographic, personality, and churchmanship variables were numerous, varied, and, with few exceptions, small in magnitude. Separate hierarchical regressions for each of the five roles indicated that the proportion of total variance explained by churchmanship was, in general, at least as great as that explained by personality, and was greater for three roles: Religious Instruction, Statutory Duties, and Role Extension. It was concluded that clergy satisfactions derived from different roles are not uniform and that churchmanship is at least as important as personality in accounting for clergy work satisfaction
Patient level pooled analysis of 68,500 patients from seven major vitamin D fracture trials in the US and Europe
Objectives To identify participants’ characteristics that influence the anti-fracture efficacy of vitamin D or vitamin
D plus calcium with respect to any fracture, hip fracture, and clinical vertebral fracture and to assess the influence of dosing regimens and co-administration of calcium. Design Individual patient data analysis using pooled data from randomised trials. Data sources Seven major randomised trials of vitamin D with calcium or vitamin D alone, yielding a total of 68 517 participants (mean age 69.9 years, range 47-107 years, 14.7% men). Study selection Studies included were randomised studies with at least one intervention arm in which vitamin D was given, fracture as an outcome, and at least 1000 participants. Data synthesis Logistic regression analysis was used to identify significant interaction terms, followed by Cox’s proportional hazards models incorporating age, sex, fracture history, and hormone therapy and bisphosphonate use. Results Trials using vitamin D with calcium showed a
reduced overall risk of fracture (hazard ratio 0.92, 95% confidence interval 0.86 to 0.99, P=0.025) and hip fracture (all studies: 0.84, 0.70 to 1.01, P=0.07; studies using 10 μg of vitamin D given with calcium: 0.74, 0.60 to 0.91, P=0.005). For vitamin D alone in daily doses of 10 μg or 20 μg, no significant effects were found. No interaction was found between fracture history and treatment
response, nor any interaction with age, sex, or hormone replacement therapy. Conclusion This individual patient data analysis indicates that vitamin D given alone in doses of 10-20 μg is not effective in preventing fractures. By contrast, calcium and vitamin D given together reduce hip fractures and total fractures, and probably vertebral fractures, irrespective of age, sex, or previous fractures.The WHI program is funded by the National Heart, Lung, and Blood Institute, National Institutes of Health, US Department of Health and Human Services through contracts N01WH22110, 24152, 32100-2, 32105-6, 32108-9, 32111-13, 32115, 32118-32119, 32122, 42107-26, 42129-32, and 44221. AA acknowledges personal funding from the UK Medical Research Council and Chief Scientist Office of the Scottish Government Health Directorates
Waiting Impulsivity: The Influence of Acute Methylphenidate and Feedback.
BACKGROUND: The ability to wait and to weigh evidence is critical to behavioral regulation. These behaviors are known as waiting and reflection impulsivity. In Study 1, we examined the effects of methylphenidate, a dopamine and norepinephrine reuptake inhibitor, on waiting and reflection impulsivity in healthy young individuals. In study 2, we assessed the role of learning from feedback in disorders of addiction. METHODS: We used the recently developed 4-Choice Serial Reaction Time task and the Beads task. Twenty-eight healthy volunteers were tested twice in a randomized, double-blind, placebo-controlled cross-over trial with 20mg methylphenidate. In the second study, we analyzed premature responses as a function of prior feedback in disorders of addiction. RESULTS: Study 1: Methylphenidate was associated with greater waiting impulsivity to a cue predicting reward along with faster responding to target onset without a generalized effect on reaction time or attention. Methylphenidate influenced reflection impulsivity based on baseline impulsivity. Study 2: More premature responses occurred after premature responses in stimulant-dependent subjects. CONCLUSIONS: We show that methylphenidate has dissociable effects on waiting and reflection impulsivity. Chronic stimulant exposure impairs learning from prior premature responses, suggesting a failure to learn that premature responding is suboptimal. These findings provide a greater mechanistic understanding of waiting impulsivity.VV and NAH are Wellcome Trust (WT) intermediate Clinical Fellows. LSM is an MRC student. The BCNI is supported by a WT and MRC grant. The authors report no conflicts of interest. TWR consults for Cambridge Cognition, Lundbeck, Teva, Shire Pharmaceuticals, Otsuka, has research grants from Lundbeck, GSK. Royalties Cambridge Cognition and receives editorial honoraria from Springer, Elsevier.This is the final version of the article. It first appeared from Oxford University Press via http://dx.doi.org/10.1093/ijnp/pyv07
Gaps in detailed knowledge of human papillomavirus (HPV) and the HPV vaccine among medical students in Scotland
<p>Background: A vaccination programme targeted against human papillomavirus (HPV) types16 and 18 was introduced in the UK in 2008, with the aim of decreasing incidence of cervical disease. Vaccine roll out to 12–13 year old girls with a catch-up programme for girls aged up to 17 years and 364 days was accompanied by a very comprehensive public health information (PHI) campaign which described the role of HPV in the development of cervical cancer.</p>
<p>Methods: A brief questionnaire, designed to assess acquisition of knowledge of HPV infection and its association to cervical cancer, was administered to two different cohorts of male and female 1st year medical students (school leavers: 83% in age range 17–20) at a UK university. The study was timed so that the first survey in 2008 immediately followed a summer's intensive PHI campaign and very shortly after vaccine roll-out (150 students). The second survey was exactly one year later over which time there was a sustained PHI campaign (213 students).</p>
<p>Results: We addressed three research questions: knowledge about three specific details of HPV infection that could be acquired from PHI, whether length of the PHI campaign and/or vaccination of females had any bearing on HPV knowledge, and knowledge differences between men and women regarding HPV. No female student in the 2008 cohort had completed the three-dose vaccine schedule compared to 58.4% of female students in 2009. Overall, participants’ knowledge regarding the sexually transmitted nature of HPV and its association with cervical cancer was high in both year groups. However, in both years, less than 50% of students correctly identified that HPV causes over 90% of cases of cervical cancer. Males gave fewer correct answers for these two details in 2009. In 2008 only around 50% of students recognised that the current vaccine protects against a limited subset of cervical cancer-causing HPV sub-types, although there was a significant increase in correct response among female students in the 2009 cohort compared to the 2008 cohort.</p>
<p>onclusions: This study highlights a lack of understanding regarding the extent of protection against cervical cancer conferred by the HPV vaccine, even among an educated population in the UK who could have a vested interest in acquiring such knowledge. The intensive PHI campaign accompanying the first year of HPV vaccination seemed to have little effect on knowledge over time. This is one of the first studies to assess detailed knowledge of HPV in both males and females. There is scope for continued improvements to PHI regarding the link between HPV infection and cervical cancer.</p>
Creating a Shared Space for English Education: The History of a Personal and Professional Collaboration
Robbins and Cooper share their experiences while developing a collaborative initiatives for English education. Collaboration was performed through the construction of shared languages and activities based on understandings of social action and used of postmodern mapping and boundary interrogation for critiquing and directing social interactions
Accuracy of Semiclassical Methods for Shape Invariant Potentials
We study the accuracy of several alternative semiclassical methods by
computing analytically the energy levels for many large classes of exactly
solvable shape invariant potentials. For these potentials, the ground state
energies computed via the WKB method typically deviate from the exact results
by about 10%, a recently suggested modification using nonintegral Maslov
indices is substantially better, and the supersymmetric WKB quantization method
gives exact answers for all energy levels.Comment: 7 pages, Latex, and two tables in postscrip
The Global Longitudinal Study of Osteoporosis in Women (GLOW): rationale and study design
SUMMARY:
The Global Longitudinal study of Osteoporosis in Women (GLOW) is a prospective cohort study involving 723 physicians and 60,393 women subjects >or=55 years. The data will provide insights into the management of fracture risk in older women over 5 years, patient experience with prevention and treatment, and distribution of risk among older women on an international basis.
INTRODUCTION:
Data from cohort studies describing the distribution of osteoporosis-related fractures and risk factors are not directly comparable and do not compare regional differences in patterns of patient management and fracture outcomes.
METHODS:
The GLOW is a prospective, multinational, observational cohort study. Practices typical of each region were identified through primary care networks organized for administrative, research, or educational purposes. Noninstitutionalized patients visiting each practice within the previous 2 years were eligible. Self-administered questionnaires were mailed, with 2:1 oversampling of women >or=65 years. Follow-up questionnaires will be sent at 12-month intervals for 5 years.
RESULTS:
A total of 723 physicians at 17 sites in ten countries agreed to participate. Baseline surveys were mailed (October 2006 to February 2008) to 140,416 subjects. After the exclusion of 3,265 women who were ineligible or had died, 60,393 agreed to participate.
CONCLUSIONS:
GLOW will provide contemporary information on patterns of management of fracture risk in older women over a 5-year period. The collection of data in a similar manner in ten countries will permit comparisons of patient experience with prevention and treatment and provide insights into the distribution of risk among older women on an international basis
The influence of nickel layer thickness on microhardness and hydrogen sorption rate of commercially pure titanium alloy
The influence of nickel coating thickness on microhardness and hydrogen sorption rate by commercially pure titanium alloy was established in this work. Coating deposition was carried out by magnetron sputtering method with prior ion cleaning of surface. It was shown that increase of sputtering time from 10 to 50 minutes leads to increase coating thickness from 0.56 to 3.78 ?m. It was established that increase of nickel coating thickness leads to increase of microhardness at loads less than 0.5 kg. Microhardness values for all samples are not significantly different at loads 1 kg. Hydrogen content in titanium alloy with nickel layer deposited at 10 and 20 minutes exceeds concentration in initial samples on one order of magnitude. Further increasing of deposition time of nickel coating leads to decreasing of hydrogen concentration in samples due to coating delamination in process of hydrogenation
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Pediatric feeding and swallowing rehabilitation: An overview
Children with neurological disabilities frequently have problems with feeding and swallowing. Such problems have a significant impact on the health and well-being of these children and their families. The primary aims in the rehabilitation of pediatric feeding and swallowing disorders are focused on supporting growth, nutrition and hydration, the development of feeding activities, and ensuring safe swallowing with the aim of preventing choking and aspiration pneumonia. Pediatric feeding and swallowing disorders can be divided into four groups: transient, developmental, chronic or progressive. This article provides an overview of the available literature about the rehabilitation of feeding and swallowing disorders in infants and children. Principles of motor control, motor learning and neuroplasticity are discussed for the four groups of children with feeding and swallowing disorders
Mood and cognition in healthy older European adults: the Zenith study
YesBackground: The study aim was to determine if state and trait intra-individual measures of everyday affect predict
cognitive functioning in healthy older community dwelling European adults (n = 387), aged 55-87 years.
Methods: Participants were recruited from centres in France, Italy and Northern Ireland. Trait level and variability in
positive and negative affect (PA and NA) were assessed using self-administered PANAS scales, four times a day for
four days. State mood was assessed by one PANAS scale prior to assessment of recognition memory, spatial working
memory, reaction time and sustained attention using the CANTAB computerized test battery.
Results: A series of hierarchical regression analyses were carried out, one for each measure of cognitive function as the
dependent variable, and socio-demographic variables (age, sex and social class), state and trait mood measures as the
predictors. State PA and NA were both predictive of spatial working memory prior to looking at the contribution of trait
mood. Trait PA and its variability were predictive of sustained attention. In the final step of the regression analyses, trait
PA variability predicted greater sustained attention, whereas state NA predicted fewer spatial working memory errors,
accounting for a very small percentage of the variance (1-2%) in the respective tests.
Conclusion: Moods, by and large, have a small transient effect on cognition in this older sample
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