Dimensional accuracy of Electron Beam Melting (EBM) additive manufacture with regard to weight optimized truss structures

The Electron Beam (EBM) additive manufacturing process is well suited to fabricating complex structural designs in Ti–6Al–4V because of the design freedoms it offers combined with strong and consistent material properties. However it has been observed that complications may arise when manufacturing truss-like structures (such as those produced via structural topology optimization) in the form of undersized features on the finished part. The issue appears to affect truss members that are not aligned with the vertical build direction, with an apparent lack of material on the negative surfaces. This effect appears to worsen with a greater angle between the truss member and the build direction, even with the use of support structures. This investigation has characterized and measured the dimensional errors that result from this issue through 3D scanning techniques. Process modifications have then been made which result in significant improvements in dimensional accuracy. This investigation highlights the importance of heat management at features with negative surfaces to yield parts that are dimensionally accurate without introducing excessive internal melt defects in the form of voids and porosity

Hubble Space Telescope studies of low-redshift Type Ia supernovae: Evolution with redshift and ultraviolet spectral trends

We present an analysis of the maximum light, near ultraviolet (NUV; 2900-5500 A) spectra of 32 low redshift (0.001<z<0.08) Type Ia supernovae (SNe Ia), obtained with the Hubble Space Telescope (HST). We combine this spectroscopic sample with high-quality gri light curves obtained with robotic telescopes to measure photometric parameters, such as stretch, optical colour, and brightness. By comparing our data to a comparable sample of SNe Ia at intermediate-z (0.4<z<0.9), we detect modest spectral evolution (3-sigma), in the sense that our mean low-z NUV spectrum has a depressed flux compared to its intermediate-z counterpart. We also see a strongly increased dispersion about the mean with decreasing wavelength, confirming the results of earlier surveys. These trends are consistent with changes in metallicity as predicted by contemporary SN Ia spectral models. We also examine the properties of various NUV spectral diagnostics in the individual spectra. We find a general correlation between stretch and the velocity (or position) of many NUV spectral features. In particular, we observe that higher stretch SNe have larger Ca II H&K velocities, that also correlate with host galaxy stellar mass. This latter trend is probably driven by the well-established correlation between stretch and stellar mass. We find no trends between UV spectral features and optical colour. Mean spectra constructed according to whether the SN has a positive or negative Hubble residual show very little difference at NUV wavelengths, indicating that the NUV evolution and variation we identify do not directly correlate with Hubble residuals. Our work confirms and strengthens earlier conclusions regarding the complex behaviour of SNe Ia in the NUV spectral region, but suggests the correlations we find are more useful in constraining progenitor models than improving the use of SNe Ia as cosmological probes.Comment: 22 pages, 14 figures, accepted in MNRAS with minor changes - Spectra are available on WISeREP, http://www.weizmann.ac.il/astrophysics/wiserep

Memory consolidation in the cerebellar cortex

Several forms of learning, including classical conditioning of the eyeblink, depend upon the cerebellum. In examining mechanisms of eyeblink conditioning in rabbits, reversible inactivations of the control circuitry have begun to dissociate aspects of cerebellar cortical and nuclear function in memory consolidation. It was previously shown that post-training cerebellar cortical, but not nuclear, inactivations with the GABA(A) agonist muscimol prevented consolidation but these findings left open the question as to how final memory storage was partitioned across cortical and nuclear levels. Memory consolidation might be essentially cortical and directly disturbed by actions of the muscimol, or it might be nuclear, and sensitive to the raised excitability of the nuclear neurons following the loss of cortical inhibition. To resolve this question, we simultaneously inactivated cerebellar cortical lobule HVI and the anterior interpositus nucleus of rabbits during the post-training period, so protecting the nuclei from disinhibitory effects of cortical inactivation. Consolidation was impaired by these simultaneous inactivations. Because direct application of muscimol to the nuclei alone has no impact upon consolidation, we can conclude that post-training, consolidation processes and memory storage for eyeblink conditioning have critical cerebellar cortical components. The findings are consistent with a recent model that suggests the distribution of learning-related plasticity across cortical and nuclear levels is task-dependent. There can be transfer to nuclear or brainstem levels for control of high-frequency responses but learning with lower frequency response components, such as in eyeblink conditioning, remains mainly dependent upon cortical memory storage

Strategies for effective unmanned aerial vehicle use in geological field studies based on cognitive science principles

Field geologists are increasingly using unmanned aerial vehicles (UAVs or drones), although their use involves significant cognitive challenges for which geologists are not well trained. On the basis of surveying the user community and documenting experts’ use in the field, we identified five major problems, most of which are aligned with well-documented limits on cognitive performance. First, the images being sent from the UAV portray the landscape from multiple different view directions. Second, even with a constant view direction, the ability to move the UAV or zoom the camera lens results in rapid changes in visual scale. Third, the images from the UAVs are displayed too quickly for users, even experts, to assimilate efficiently. Fourth, it is relatively easy to get lost when flying, particularly if the user is unfamiliar with the area or with UAV use. Fifth, physical limitations on flight time are a source of stress, which renders the operator less effective. Many of the strategies currently employed by field geologists, such as postprocessing and photogrammetry, can reduce these problems. We summarize the cognitive science basis for these issues and provide some new strategies that are designed to overcome these limitations and promote more effective UAV use in the field. The goal is to make UAV-based geological interpretations in the field possible by recognizing and reducing cognitive loa

Mio-Pliocene Faunal Exchanges and African Biogeography: The Record of Fossil Bovids

The development of the Ethiopian biogeographic realm since the late Miocene is here explored with the presentation and review of fossil evidence from eastern Africa. Prostrepsiceros cf. vinayaki and an unknown species of possible caprin affinity are described from the hominid-bearing Asa Koma and Kuseralee Members (∼5.7 and ∼5.2 Ma) of the Middle Awash, Ethiopia. The Middle Awash Prostrepsiceros cf. vinayaki constitutes the first record of this taxon from Africa, previously known from the Siwaliks and Arabia. The possible caprin joins a number of isolated records of caprin or caprin-like taxa recorded, but poorly understood, from the late Neogene of Africa. The identification of these two taxa from the Middle Awash prompts an overdue review of fossil bovids from the sub-Saharan African record that demonstrate Eurasian affinities, including the reduncin Kobus porrecticornis, and species of Tragoportax. The fossil bovid record provides evidence for greater biological continuity between Africa and Eurasia in the late Miocene and earliest Pliocene than is found later in time. In contrast, the early Pliocene (after 5 Ma) saw the loss of any significant proportions of Eurasian-related taxa, and the continental dominance of African-endemic taxa and lineages, a pattern that continues today

Mass Determination and Detection of the Onset of Chromospheric Activity for the Sub-Stellar Object in EF Eridani

EF Eri is a magnetic cataclysmic variable that has been in a low accretion state for the past nine years. Low state optical spectra reveal the underlying Zeeman-split white dwarf absorption lines. These features are used to determine a value of 13-14 MG as the white dwarf field strength. Recently, 5-7 years into the low state, Balmer and other emission lines have appeared in the optical. An analysis of the H$\alpha$ emission line yields the first radial velocity solution for EF Eri, leading to a spectroscopic ephemeris for the binary and, using the best available white dwarf mass of 0.6M${\odot}$, a mass estimate for the secondary of 0.055M${\odot}$. For a white dwarf mass of 0.95M${\odot}$, the average for magnetic white dwarfs, the secondary mass increases to 0.087M${\odot}$. At EF Eri's orbital period of 81 minutes, this higher mass secondary could not be a normal star and still fit within the Roche lobe. The source of the Balmer and other emission lines is confirmed to be from the sub-stellar secondary and we argue that it is due to stellar activity. We compare EF Eri's emission line spectrum and activity behavior to that recently observed in AM Her and VV Pup and attributed to stellar activity. We explore observations and models originally developed for V471 Tau, for the RS CVn binaries, and for extra-solar planets. We conclude that irradiation of the secondary in EF Eri and similar systems is unlikely and, in polars, the magnetic field interaction between the two stars (with a possible tidal component) is a probable mechanism which would concentrate chromospheric activity on the secondary near the sub-stellar point of the white dwarf.Comment: 49 pages, 12 figures Accepted to ApJ (Main journal

Measurement of triple gauge boson couplings from W⁺W⁻ production at LEP energies up to 189 GeV

A measurement of triple gauge boson couplings is presented, based on W-pair data recorded by the OPAL detector at LEP during 1998 at a centre-of-mass energy of 189 GeV with an integrated luminosity of 183 pb⁻¹. After combining with our previous measurements at centre-of-mass energies of 161–183 GeV we obtain κ = 0.97_{-0.16}^{+0.20}, g_{1}^{z} = 0.991_{-0.057}^{+0.060} and λ = -0.110_{-0.055}^{+0.058}, where the errors include both statistical and systematic uncertainties and each coupling is determined by setting the other two couplings to their Standard Model values. These results are consistent with the Standard Model expectations

The medical student

The Medical Student was published from 1888-1921 by the students of Boston University School of Medicine

Mutation of the Diamond-Blackfan Anemia Gene Rps7 in Mouse Results in Morphological and Neuroanatomical Phenotypes

The ribosome is an evolutionarily conserved organelle essential for cellular function. Ribosome construction requires assembly of approximately 80 different ribosomal proteins (RPs) and four different species of rRNA. As RPs co-assemble into one multi-subunit complex, mutation of the genes that encode RPs might be expected to give rise to phenocopies, in which the same phenotype is associated with loss-of-function of each individual gene. However, a more complex picture is emerging in which, in addition to a group of shared phenotypes, diverse RP gene-specific phenotypes are observed. Here we report the first two mouse mutations (Rps7(Mtu) and Rps7(Zma)) of ribosomal protein S7 (Rps7), a gene that has been implicated in Diamond-Blackfan anemia. Rps7 disruption results in decreased body size, abnormal skeletal morphology, mid-ventral white spotting, and eye malformations. These phenotypes are reported in other murine RP mutants and, as demonstrated for some other RP mutations, are ameliorated by Trp53 deficiency. Interestingly, Rps7 mutants have additional overt malformations of the developing central nervous system and deficits in working memory, phenotypes that are not reported in murine or human RP gene mutants. Conversely, Rps7 mouse mutants show no anemia or hyperpigmentation, phenotypes associated with mutation of human RPS7 and other murine RPs, respectively. We provide two novel RP mouse models and expand the repertoire of potential phenotypes that should be examined in RP mutants to further explore the concept of RP gene-specific phenotypes.This research was supported in part by the Intramural Research Program of NHGRI, NIH, and the Wellcome Trust and by NHMRC Australia grant 366746. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript

Measurement of triple gauge boson couplings from WW production at LEP energies up to 189 GeV

A measurement of triple gauge boson couplings is presented, based on W-pair data recorded by the OPAL detector at LEP during 1998 at a centre-of-mass energy of 189 GeV with an integrated luminosity of 183 pb^-1. After combining with our previous measurements at centre-of-mass energies of 161-183 GeV we obtain k_g=0.97 +0.20 -0.16, g_1^z=0.991 +0.060 -0.057 and lambda_g=-0.110 +0.058 -0.055, where the errors include both statistical and systematic uncertainties and each coupling is determined by setting the other two couplings to their SM values. These results are consistent with the Standard Model expectations.Comment: 28 pages, 8 figures, submitted to Eur. Phys. J.