196 research outputs found

    Détection et localisation d'objets stationnaires par une paire de caméras PTZ

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    Session "Articles"National audienceDans ce papier, nous proposons une approche originale pour détecter et localiser des objets stationnaires sur une scène étendue en exploitant une paire de caméras PTZ. Nous proposons deux contributions principales. Tout d'abord, nous présentons une méthode de détection et de segmentation d'objets stationnaires. Celle-ci est basée sur la réidentification de descripteurs de l'avant-plan et une segmentation de ces blobs en objets à l'aide de champs de Markov. La seconde contribution concerne la mise en correspondance entre les deux PTZ des silhouettes d'objets détectées dans chaque image

    Student Readiness of Colleges: A Qualitative Study

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    Using the framework of belonging, this qualitative study explores how one upper midwestern college engages in student-readiness and explores the disconnects that create barriers to student-readiness. The study investigates ‘student readiness’ broadly through the literature and more specifically by narrowing efforts to a detailed examination of one college by conducting interviews, observations, and collecting artifacts. The results of the study revealed that the college addressed student readiness differently depending on perspectives of staff/faculty, administration, and students. Three themes emerged after coding and examination of the data: supports, community and disconnect

    Reflections on the coproduction of a crisis-focused intervention for inpatient settings underpinned by a Cognitive Behavioural Therapy for psychosis (CBTp) model

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    Background: Psychological interventions delivered in inpatient settings have rarely been coproduced with those who receive them. The aim of this study is to outline the coproduction process which led to the development of an adapted inpatient intervention underpinned by a Cognitive Behaviour Therapy for psychosis model. / Method: Our coproduction group was comprised of experts by experience, family and carers, multi-disciplinary clinicians, and researchers. The group met monthly to develop the intervention and focused on eight key areas of the intervention, including therapist values, assessment, formulation, coping strategies, crisis/safety plans, and discharge plans. / Results: The coproduction panel highlighted the importance of flexible delivery of the intervention, developing a trusting relationship with the therapist, advocacy, prioritising patient safety on the ward, managing the impacts of inpatient care, preparing for discharge, and having family, carer and community involvement. Challenges of the coproduction process included having a pre-existing intervention model that was being adapted rather than coproducing a new one, discussing emotionally charged issues, and having limited time to coproduce the intervention. / Discussion: Coproduction brought immense value to the development of this intervention, ensuring it was culturally competent and suitable for the inpatient setting. Further research should be undertaken exploring the coproduction process applied to clinical research

    Relation entre composition corporelle et valeurs spirométriques dans la population adulte de Kinshasa de 20 à 70 ans: Body composition and spirometric values in an adult population of Kinshasa, aged 20-70 years

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    Context. Impact of individual anthropometric measures on spirometric values has been previously established. The relevance of body mass indices (BMI) is increasingly being considered, especially in the establishment of reference spirometric equations. Objective. To assess the influence of body composition on spirometric values in healthy adults. Methods. In a cross-sectional survey, spirometric and body composition data of participants were analyzed. Spirometry was performed using a SPIROBANK A23-OU and body indices measured with an OMRON brand impedance meter, type BF 511. Multivariate linear regression helped to determine association between studied parameters, stratified by sex and age groups. Results. A total of 7443 subjects (males, 56.9 %), median age of 37 years for men and 39 years for women were included. A negative correlation regardless of gender, was observed between spirometric values (FEV1, FVC, PEF° and body mass indices including: fat mass (Men vs Women: r= 0.009, P < 0.001 vs r= 0.003, P=0.148), visceral fat, waist size and BMI. Differences were significantely linked to the proportion of fat mass and/or a BMI ≥ 30 Kg/m². Lean mass, on the other hand, appeared to positively influence respiratory function in both genders (r= 0.003; P=0.218 vs r=0.018, P< 0.0001). Conclusion. The study emphasizes the relevance of integrating anthropometric and body composition data in the determination of spirometric reference values. Larger community based surveys are needed to validate the reference equations for futher use. Contexte. Les données anthropométriques influencent les valeurs spirométriques d’un individu. La contribution des indices de masse corporelle est de plus en plus considérée, surtout dans l’établissement des équations de référence pour une population donnée. Objectif. Evaluer l’impact de la composition corporelle sur les valeurs spirométriques dans une population des sujets sains. Méthodes. L’enquête transversale a analysé les données spirométriques et les indices de la composition corporelle (IMC) de participants. Les valeurs spirométriques ont été mesurées à l’aide d’un spiromètre de marque SPIROBANK A23-0U, et les indices de masse corporelle, à l’aide d’un impédancimètre de marque OMRON, type BF 511. Les associations ont été recherchées entre paramètres étudiés stratifiés par sexe et en groupes d’âge, à l’aide d’une analyse multivariée par régression linéaire. Résultats. Au total, 7443 sujets (sexe masculin, 56,9%), d’âge médian de 37 ans chez les hommes et 39 ans chez les femmes ont été inclus. Une corrélation négative, indépendamment du sexe, a été observée entre les valeurs spirométriques (VEMS, CVF, DEP) et les indices de masse corporelle dont : la masse grasse (Hommes vs Femmes : r =0,009, P<0,0001 vs r=0,003, P=0,148), la graisse viscérale, le tour de taille et l’IMC. Cette dernière était plus marquée chez les sujets avec proportion plus importante de masse grasse et/ou un IMC ≥ 30 Kg par m². La masse maigre quant à elle, semblait positivement influencer la fonction respiratoire et ce, indépendamment du sexe (r= 0,003 ; P= 0,218 vs r=0,018, P < 0,0001). Conclusion : Cette étude renforce la pertinence d’intégrer les données anthropométriques et de la composition corporelle dans la détermination des valeurs spirométriques de référence. Des enquêtes multicentriques s’imposent, en vue de la validation des équations de référence. &nbsp

    Information and Communication Technology Adoption and the Growth of Small Medium Enterprises in Uganda: Empirical Evidence from Kampala City Council Authority

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    The study used cross sectional study design and data were collected from business owners operating within the divisions of Kampala Capital City Authority. The study found out that the level of ICT adoption in Kampala Capital City Authority was moderate. ICT adoption was mostly marked with establishment of separate IT department, use of bulk SMS, printers, scanners and photocopiers. Specialized ICT skills, regular updates and outsourcing of ICT functions appeared to be a key challenge business face in ICT adoption. The findings however, indicated that growth of SMEs is a conglomeration, of which adoption of ICT is a microcosm. The study recommends that Government of Uganda through Ministry of Science Technology and Innovation and Ministry of Finance Planning and Economic Development should consider promoting ICT business growth by sponsoring business software development, and distributing the same at subsidized costs. Training institutions should strengthen the ICT training programs by aligning them to the required job demands as dictated in the field of business. Government should also promote the application and adoption of ICT e-business by slashing the exorbitant taxes charged on the use of these products. Government should stimulate entrepreneurship development training to curb the shortfalls in staff competence, individual job creation and profitability skills

    Consciousness in Artificial Intelligence: Insights from the Science of Consciousness

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    Whether current or near-term AI systems could be conscious is a topic of scientific interest and increasing public concern. This report argues for, and exemplifies, a rigorous and empirically grounded approach to AI consciousness: assessing existing AI systems in detail, in light of our best-supported neuroscientific theories of consciousness. We survey several prominent scientific theories of consciousness, including recurrent processing theory, global workspace theory, higher-order theories, predictive processing, and attention schema theory. From these theories we derive "indicator properties" of consciousness, elucidated in computational terms that allow us to assess AI systems for these properties. We use these indicator properties to assess several recent AI systems, and we discuss how future systems might implement them. Our analysis suggests that no current AI systems are conscious, but also suggests that there are no obvious technical barriers to building AI systems which satisfy these indicators

    Intravitreal Gene Therapy vs. Natural History in Patients With Leber Hereditary Optic Neuropathy Carrying the m.11778G>A <i>ND4</i> Mutation: Systematic Review and Indirect Comparison.

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    Objective: This work aimed to compare the evolution of visual outcomes in Leber hereditary optic neuropathy (LHON) patients treated with intravitreal gene therapy to the spontaneous evolution in prior natural history (NH) studies. Design: A combined analysis of two phase three randomized, double-masked, sham-controlled studies (REVERSE and RESCUE) and their joint long-term extension trial (CLIN06) evaluated the efficacy of rAAV2/2-ND4 vs. 11 pooled NH studies used as an external control. Subjects: The LHON subjects carried the m.11778G>A ND4 mutation and were aged ≥15 years at onset of vision loss. Methods: A total of 76 subjects received a single intravitreal rAAV2/2-ND4 injection in one eye and sham injection in the fellow eye within 1 year after vision loss in REVERSE and RESCUE. Both eyes were considered as treated due to the rAAV2/2-ND4 treatment efficacy observed in the contralateral eyes. Best corrected visual acuity (BCVA) from REVERSE, RESCUE, and CLIN06 up to 4.3 years after vision loss was compared to the visual acuity of 208 NH subjects matched for age and ND4 genotype. The NH subjects were from a LHON registry (REALITY) and from 10 NH studies. A locally estimated scatterplot smoothing (LOESS), non-parametric, local regression model was used to modelize visual acuity curves over time, and linear mixed model was used for statistical inferences. Main Outcome Measures: The main outcome measure was evolution of visual acuity from 12 months after vision loss, when REVERSE and RESCUE patients had been treated with rAAV2/2-ND4. Results: The LOESS curves showed that the BCVA of the treated patients progressively improved from month 12 to 52 after vision loss. At month 48, there was a statistically and clinically relevant difference in visual acuity of -0.33 logarithm of the minimal angle of resolution (LogMAR) (16.5 ETDRS letters equivalent) in favor of treated eyes vs. NH eyes (p p p Conclusions: The m.11778G>A LHON patients treated with rAAV2/2-ND4 exhibited an improvement of visual acuity over more than 4 years after vision loss to a degree not demonstrated in NH studies. Clinical Trial Registration: NCT02652767, NCT02652780, NCT03406104, and NCT03295071

    Multi-site comparison of factors influencing progress of African insecticide testing facilities towards an international Quality Management System certification

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    Background Insecticidal mosquito vector control products are vital components of malaria control programmes. Test facilities are key in assessing the effectiveness of vector control products against local mosquito populations, in environments where they will be used. Data from these test facilities must be of a high quality to be accepted by regulatory authorities, including the WHO Prequalification Team for vector control products. In 2013–4, seven insecticide testing facilities across sub-Saharan Africa, with technical and financial support from Innovative Vector Control Consortium (IVCC), began development and implementation of quality management system compliant with the principles of Good Laboratory Practice (GLP) to improve data quality and reliability. Methods and principle findings We conducted semi-structured interviews, emails, and video-call interviews with individuals at five test facilities engaged in the IVCC-supported programme and working towards or having achieved GLP. We used framework analysis to identify and describe factors affecting progress towards GLP. We found that eight factors were instrumental in progress, and that test facilities had varying levels of control over these factors. They had high control over the training programme, project planning, and senior leadership support; medium control over infrastructure development, staff structure, and procurement; and low control over funding the availability and accessibility of relevant expertise. Collaboration with IVCC and other partners was key to overcoming the challenges associated with low and medium control factors. Conclusion For partnership and consortia models of research capacity strengthening, test facilities can use their own internal resources to address identified high-control factors. Project plans should allow additional time for interaction with external agencies to address medium-control factors, and partners with access to expertise and funding should concentrate their efforts on supporting institutions to address low-control factors. In practice, this includes planning for financial sustainability at the outset, and acting to strengthen national and regional training capacity
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