348 research outputs found
Dissemination of patient blood management practices in Swiss intensive care units: a cross-sectional survey
BACKGROUND
Patient blood management (PBM) promotes the routine detection and treatment of anaemia before surgery, optimising the management of bleeding disorders, thus minimising iatrogenic blood loss and pre-empting allogeneic blood utilisation. PBM programmes have expanded from the elective surgical setting to nonsurgical patients, including those in intensive care units (ICUs), but their dissemination in a whole country is unknown.
METHODS
We performed a cross-sectional, anonymous survey (10 October 2018 to 13 March 2019) of all ordinary medical members of the Swiss Society of Intensive Care Medicine and the registered ICU nurses from the 77 certified adult Swiss ICUs. We analysed PBM-related interventions adopted in Swiss ICUs and related them to the spread of PBM in Swiss hospitals. We explored blood test ordering policies, blood-sparing strategies and red blood cell-related transfusion practices in ICUs.
RESULTS
A total of 115 medical doctors and 624 nurses (response rates 27% and 30%, respectively) completed the surveys. Hospitals had implemented a PBM programme according to 42% of physicians, more commonly in Switzerland's German-speaking regions (Odds Ratio [OR] 3.39, 95% confidence interval [CI] 1.23-9.35; p = 0.018) and in hospitals with more than 500 beds (OR 3.91, 95% CI 1.48-10.4; p = 0.006). The PBM programmes targeted the detection and correction of anaemia before surgery (79%), minimising perioperative blood loss (94%) and optimising anaemia tolerance (98%). Laboratory tests were ordered in 70.4% by the intensivist during morning rounds; the nurses performed arterial blood gas analyses autonomously in 48.4%. Blood-sparing techniques were used by only 42.1% of nurses (263 of 624, missing: 6) and 47.0% of physicians (54 of 115). Approximately 60% of respondents used an ICU-specific transfusion guideline. The reported haemoglobin threshold for the nonbleeding ICU population was 70 g/l and, therefore, was at the lower limit of current guidelines.
CONCLUSIONS
Based on this survey, the estimated proportion of the intensivists working in hospitals with a PBM initiative is 42%, with significant variability between regions and hospitals of various sizes. The risk of iatrogenic anaemia is relevant due to liberal blood sample collection practices and the underuse of blood-sparing techniques. The reported transfusion threshold suggests excellent adherence to current international ICU-specific transfusion guidelines
Radiation damage of silicon strip detectors in the NA50 experiment
Abstract During operation of the multiplicity detector in the NA50 experiment the single sided AC-coupled p-on-n silicon strip detectors were exposed to charged particle fluences up to 10 14 eq n/cm 2 and ionising doses up to 20 Mrad, with a very non-uniform radiation spatial distribution. Radiation effects in the detectors observed during the '96 lead ion run as well as results of the post-run measurements are presented in this paper
Analysis of radiation effects on silicon strip detectors in the NA50 experiment
Abstract During the operation of the Multiplicity Detector in the NA50 experiment the single sided AC-coupled p-on-n silicon strip detectors were exposed to charged particle fluences resulting in an equivalent 1 MeV neutron fluence up to 10 14 eq. n/cm 2 and a total ionising dose up to 20 Mrad, with a very non-uniform radiation spatial distribution. In this paper detailed analysis of radiation effects observed on the detectors during the 1996 lead ion run as well as results of measurements performed after the run are presented
J/psi azimuthal anisotropy relative to the reaction plane in Pb-Pb collisions at 158 GeV per nucleon
The J/ azimuthal distribution relative to the reaction plane has been
measured by the NA50 experiment in Pb-Pb collisions at 158 GeV/nucleon. Various
physical mechanisms related to charmonium dissociation in the medium created in
the heavy ion collision are expected to introduce an anisotropy in the
azimuthal distribution of the observed J/ mesons at SPS energies. Hence,
the measurement of J/ elliptic anisotropy, quantified by the Fourier
coefficient v of the J/ azimuthal distribution relative to the
reaction plane, is an important tool to constrain theoretical models aimed at
explaining the anomalous J/ suppression observed in Pb-Pb collisions. We
present the measured J/ yields in different bins of azimuthal angle
relative to the reaction plane, as well as the resulting values of the Fourier
coefficient v as a function of the collision centrality and of the
J/ transverse momentum. The reaction plane has been estimated from the
azimuthal distribution of the neutral transverse energy detected in an
electromagnetic calorimeter. The analysis has been performed on a data sample
of about 100 000 events, distributed in five centrality or p
sub-samples. The extracted v values are significantly larger than zero
for non-central collisions and are seen to increase with p.Comment: proceedings of HP08 conference corrected a typo in one equatio
The silicon multiplicity detector for the NA50 experiment at CERN
The design, operation and performance of the silicon strip Multiplicity Detector for the heavy-ion experiment NA50 at CERN are presented. The main features of the detector are high speed (50 MHz sampling frequency), high granularity (more than 13,000 strips), and good radiation resistance. The detector provided a measurement ofevent centrality in Pb–Pb collisions, as well as target identification and the measurement ofcharged particle pseudorapidity distributions as a function of centrality. r 2002 Elsevier Science B.V. All rights reserved. PACS: 29.4
The silicon Multiplicity Detector for the NA50 experiment
Abstract The operation and performance of the silicon strip Multiplicity Detector in the heavy-ion experiment NA50 at CERN are presented together with a selection of physics results. The main features of the detector are high speed (50 MHz sampling frequency), high granularity (more than 13,000 strips), and good radiation resistance. The detector provided a measurement of event centrality in Pb–Pb collisions, as well as target identification and the measurement of charged particle pseudorapidity distributions as a function of centrality
Bottomonium and Drell-Yan production in p-A collisions at 450 GeV
The NA50 Collaboration has measured heavy-quarkonium production in p-A
collisions at 450 GeV incident energy (sqrt(s) = 29.1 GeV). We report here
results on the production of the Upsilon states and of high-mass Drell-Yan muon
pairs (m > 6 GeV). The cross-section at midrapidity and the A-dependence of the
measured yields are determined and compared with the results of other
fixed-target experiments and with the available theoretical estimates. Finally,
we also address some issues concerning the transverse momentum distributions of
the measured dimuons.Comment: 18 pages, 9 figures, to be published in Phys. Lett.
A new measurement of J/psi suppression in Pb-Pb collisions at 158 GeV per nucleon
We present a new measurement of J/psi production in Pb-Pb collisions at 158
GeV/nucleon, from the data sample collected in year 2000 by the NA50
Collaboration, under improved experimental conditions with respect to previous
years. With the target system placed in vacuum, the setup was better adapted to
study, in particular, the most peripheral nuclear collisions with unprecedented
accuracy. The analysis of this data sample shows that the (J/psi)/Drell-Yan
cross-sections ratio measured in the most peripheral Pb-Pb interactions is in
good agreement with the nuclear absorption pattern extrapolated from the
studies of proton-nucleus collisions. Furthermore, this new measurement
confirms our previous observation that the (J/psi)/Drell-Yan cross-sections
ratio departs from the normal nuclear absorption pattern for semi-central Pb-Pb
collisions and that this ratio persistently decreases up to the most central
collisions.Comment: 19 pages, 10 figures. Submitted to Eur. Phys. J.
The dependence of the anomalous J/psi suppression on the number of participant nucleons
The observation of an anomalous J/psi suppression in Pb-Pb collisions by the NA50 Collaboration can be considered as the most striking indication for the deconfinement of quarks and gluons at SPS energies. In this Letter, we determine the J/psi suppression pattern as a function of the forward hadronic energy E-ZDC measured in a Zero Degree Calorimeter (ZDC). The direct connection between EZDC and the geometry of the collision allows us to calculate, within a Glauber approach, the precise relation between the number of participant nucleons N-part and E-ZDC. Then, we check if the experimental data can be better explained by a sudden or a smooth onset of the anomalous J/psi suppression as a function of the number of participants. (C) 2001 Elsevier Science B.V. All rights reserved.info:eu-repo/semantics/publishedVersio
The primary cosmic ray composition between 10**15 and 10**16 eV from Extensive Air Showers electromagnetic and TeV muon data
The cosmic ray primary composition in the energy range between 10**15 and
10**16 eV, i.e., around the "knee" of the primary spectrum, has been studied
through the combined measurements of the EAS-TOP air shower array (2005 m
a.s.l., 10**5 m**2 collecting area) and the MACRO underground detector (963 m
a.s.l., 3100 m w.e. of minimum rock overburden, 920 m**2 effective area) at the
National Gran Sasso Laboratories. The used observables are the air shower size
(Ne) measured by EAS-TOP and the muon number (Nmu) recorded by MACRO. The two
detectors are separated on average by 1200 m of rock, and located at a
respective zenith angle of about 30 degrees. The energy threshold at the
surface for muons reaching the MACRO depth is approximately 1.3 TeV. Such muons
are produced in the early stages of the shower development and in a kinematic
region quite different from the one relevant for the usual Nmu-Ne studies. The
measurement leads to a primary composition becoming heavier at the knee of the
primary spectrum, the knee itself resulting from the steepening of the spectrum
of a primary light component (p, He). The result confirms the ones reported
from the observation of the low energy muons at the surface (typically in the
GeV energy range), showing that the conclusions do not depend on the production
region kinematics. Thus, the hadronic interaction model used (CORSIKA/QGSJET)
provides consistent composition results from data related to secondaries
produced in a rapidity region exceeding the central one. Such an evolution of
the composition in the knee region supports the "standard" galactic
acceleration/propagation models that imply rigidity dependent breaks of the
different components, and therefore breaks occurring at lower energies in the
spectra of the light nuclei.Comment: Submitted to Astroparticle Physic
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