From Design to Production Control Through the Integration of Engineering Data Management and Workflow Management Systems

At a time when many companies are under pressure to reduce "times-to-market" the management of product information from the early stages of design through assembly to manufacture and production has become increasingly important. Similarly in the construction of high energy physics devices the collection of (often evolving) engineering data is central to the subsequent physics analysis. Traditionally in industry design engineers have employed Engineering Data Management Systems (also called Product Data Management Systems) to coordinate and control access to documented versions of product designs. However, these systems provide control only at the collaborative design level and are seldom used beyond design. Workflow management systems, on the other hand, are employed in industry to coordinate and support the more complex and repeatable work processes of the production environment. Commercial workflow products cannot support the highly dynamic activities found both in the design stages of product development and in rapidly evolving workflow definitions. The integration of Product Data Management with Workflow Management can provide support for product development from initial CAD/CAM collaborative design through to the support and optimisation of production workflow activities. This paper investigates this integration and proposes a philosophy for the support of product data throughout the full development and production lifecycle and demonstrates its usefulness in the construction of CMS detectors.Comment: 18 pages, 13 figure

Detector Construction Management and Quality Control: Establishing and Using a CRISTAL System

The CRISTAL (Cooperating Repositories and an Information System for Tracking Assembly Lifecycles) project is delivering a software system to facilitate the management of the engineering data collected at each stage of production of CMS. CRISTAL captures all the physical characteristics of CMS components as each sub-detector is tested and assembled. These data are retained for later use in areas such as detector slow control, calibration and maintenance. CRISTAL must, therefore, support different views onto its data dependent on the role of the user. These data viewpoints are investigated in this paper. In the recent past two CMS Notes have been written about CRISTAL. The first note, CMS 1996/003, detailed the requirements for CRISTAL, its relationship to other CMS software, its objectives and reviewed the technology on which it would be based. CMS 1997/104 explained some important design concepts on which CRISTAL is and showed how CRISTAL integrated the domains of product data man- agement and workflow management. This note explains, through the use of diagrams, how CRISTAL can be established for detector production and used as the information source for analyses, such as calibration and slow controls, carried out by physicists. The reader should consult the earlier CMS Notes and conference papers for technical detail on CRISTAL - this note concentrates on issues surrounding the practical use of the CRISTAL software.Comment: 16 pages, 14 figure

CMS physics technical design report : Addendum on high density QCD with heavy ions

Peer reviewe

Relations entre structures et repartition des aquiferes dans les massifs de la Nerthe et de l'Etoile, Bouches-du-Rhone, France

SIGLECNRS T 57827 / INIST-CNRS - Institut de l'Information Scientifique et TechniqueFRFranc

Nouvelle approche synthétique pour la préparation de l'hypoxyxylérone et d'analogues

Ce travail de thèse décrit une nouvelle approche synthétique pour la préparation de l'hypoxyxylérone et de ses analogues. L'hypoxyxylérone est un composé pentacyclique aromatique isolé du champignon Hypoxylon Fragiform, présentant in vitro d'intéressantes propriétés cytotoxiques par un mécanisme d'action ayant pour cible la topoisomérase I. La mise au point d'une systhèse s'avére nécessaire pour développer un programme d'études relations structure/activité et contribuer à l'amélioration de la biodisponibilité du produit naturel. La stratégie synthétique présentée repose sur la préparation de dibenzoxanthones, issues d'une réaction de condensation entre deux précurseurs aromatiques : un homophtalate de diméthyle et une acétonaphtone polyfonctionelle de type 2-acétyl-1-hydroxynaphtalène. Cette réaction clef permet d'accéder directement à des dibenzoxanthones diversement substituées. L'hypoxyxylérone est obtenue sous forme pentaméthylée à partir d'une dibenzoxanthone dûment fonctionnalisée. La prépartion de l'analogue désoxy au niveau de la position benzylique de l'hypoxyxylérone a été réalisée.GRENOBLE1-BU Sciences (384212103) / SudocSudocFranceF

Carrageenan biosynthesis in red algae: A review

In this review, we summarize the current state of knowledge on the biosynthesis of carrageenan by exploring both the enzyme activities and their localizations. Genomic data, with the sequencing of the genome of Chondrus crispus and the first transcriptomic study into the life cycle stages of this organism, as well as fine carbohydrate structural determination of matrix glycans, provide leads in the study of carrageenan anabolism. Comparison to related carbohydrate-active enzymes, detailed phylogenies alongside classic histochemical studies and radioactivity assays, help predict the localization of the carrageenan-related enzyme biochemistries. Using these insights, we provide an updated model of carrageenan biosynthesis which contributes to understanding the ancestral pathway of sulfated polysaccharide biosynthesis in eukaryotes