68 research outputs found
Raman signatures of classical and quantum phases in coupled dots: A theoretical prediction
We study electron molecules in realistic vertically coupled quantum dots in a
strong magnetic field. Computing the energy spectrum, pair correlation
functions, and dynamical form factor as a function of inter-dot coupling via
diagonalization of the many-body Hamiltonian, we identify structural
transitions between different phases, some of which do not have a classical
counterpart. The calculated Raman cross section shows how such phases can be
experimentally singled out.Comment: 9 pages, 2 postscript figures, 1 colour postscript figure, Latex 2e,
Europhysics Letters style and epsfig macros. Submitted to Europhysics Letter
Enhancing single-molecule photostability by optical feedback from quantum-jump detection
We report an optical technique that yields an enhancement of single-molecule
photostability, by greatly suppressing photobleaching pathways which involve
photoexcitation from the triplet state. This is accomplished by dynamically
switching off the excitation laser when a quantum-jump of the molecule to the
triplet state is optically detected. This procedure leads to a lengthened
single-molecule observation time and an increased total number of detected
photons. The resulting improvement in photostability unambiguously confirms the
importance of photoexcitation from the triplet state in photobleaching
dynamics, and may allow the investigation of new phenomena at the
single-molecule level
Search for Direct CP Violation in Non-Leptonic Decays of Charged and Hyperons
A search for direct CP violation in the non-leptonic decays of hyperons has
been performed. In comparing the product of the decay parameters,
, in terms of an asymmetry parameter,
, between hyperons and anti-hyperons in the charged and decay sequence, we found no evidence of
direct CP violations. The parameter was measured to be .Comment: Submitted for publication; RevTex, 13 pages, 4 figure
Second-harmonic generation from coupled plasmon modes in a single dimer of gold nanospheres
We show that a dimer made of two gold nanospheres exhibits a remarkable
efficiency for second-harmonic generation under femtosecond optical excitation.
The detectable nonlinear emission for the given particle size and excitation
wavelength arises when the two nanoparticles are as close as possible to
contact, as in situ controlled and measured using the tip of an atomic force
microscope. The excitation wavelength dependence of the second-harmonic signal
supports a coupled plasmon resonance origin with radiation from the dimer gap.
This nanometer-size light source might be used for high-resolution near-field
optical microscopy.Comment: 6 pages, 5 figure
Measurement of Decay Parameters for Decay
Based on 1.35 million polarized events, we measure the parameter
to be for
decay. New results for the parameters
and are also presented. Assuming that the
CP-violating phase-shift difference is negligible, we deduce the strong
phase-shift difference between the P-wave and S-wave amplitudes of the
final state to be . This strong phase-shift difference reduces the theoretical
uncertainty in estimating the level of CP violation in -hyperon decay.Comment: To be published in Physical Review Letter
The conserved Fanconi anemia nuclease Fan1 and the SUMO E3 ligase Pli1 act in two novel Pso2-independent pathways of DNA interstrand crosslink repair in yeast
DNA interstrand cross-links (ICLs) represent a physical barrier to the progression of cellular machinery involved in DNA metabolism. Thus, this type of adduct represents a serious threat to genomic stability and as such, several DNA repair pathways have evolved in both higher and lower eukaryotes to identify this type of damage and restore the integrity of the genetic material. Human cells possess a specialized ICL-repair system, the Fanconi anemia (FA) pathway. Conversely yeasts rely on the concerted action of several DNA repair systems. Recent work in higher eukaryotes identified and characterized a novel conserved FA component, FAN1 (Fanconi anemia-associated nuclease 1, or FANCD2/FANCI-associated nuclease 1). In this study, we characterize Fan1 in the yeast Schizosaccharomyces pombe. Using standard genetics, we demonstrate that Fan1 is a key component of a previously unidentified ICL-resolution pathway. Using high-throughput synthetic genetic arrays, we also demonstrate the existence of a third pathway of ICL repair, dependent on the SUMO E3 ligase Pli1. Finally, using sequence-threaded homology models, we predict and validate key residues essential for Fan1 activity in ICL repair
Engineering the fatty acid synthesis pathway in Synechococcus elongatus PCC 7942 improves omega-3 fatty acid production
Background: The microbial production of fatty acids has received great attention in the last few years as feedstock for the production of renewable energy. The main advantage of using cyanobacteria over other organisms is their ability to capture energy from sunlight and to transform CO2 into products of interest by photosynthesis, such as fatty acids. Fatty acid synthesis is a ubiquitous and well-characterized pathway in most bacteria. However, the activity of the enzymes involved in this pathway in cyanobacteria remains poorly explored. Results: To characterize the function of some enzymes involved in the saturated fatty acid synthesis in cyanobacteria, we genetically engineered Synechococcus elongatus PCC 7942 by overexpressing or deleting genes encoding enzymes of the fatty acid synthase system and tested the lipid profile of the mutants. These modifications were in turn used to improve alpha-linolenic acid production in this cyanobacterium. The mutant resulting from fabF overexpression and fadD deletion, combined with the overexpression of desA and desB desaturase genes from Synechococcus sp. PCC 7002, produced the highest levels of this omega-3 fatty acid. Conclusions: The fatty acid composition of S. elongatus PCC 7942 can be significantly modified by genetically engineering the expression of genes coding for the enzymes involved in the first reactions of fatty acid synthesis pathway. Variations in fatty acid composition of S. elongatus PCC 7942 mutants did not follow the pattern observed in Escherichia coli derivatives. Some of these modifications can be used to improve omega-3 fatty acid production. This work provides new insights into the saturated fatty acid synthesis pathway and new strategies that might be used to manipulate the fatty acid content of cyanobacteria.Work in the FDLC laboratory was financed by the Spanish Ministry of Economy and Competitivity (MINECO) Grant BFU2014-55534-C2-1-P. MSM. was recipientof a Ph.D. fellowship (BES-2012-057387) from MINECO
Low-Energy Parity-Violation and New Physics
The new physics sensitivity of a variety of low-energy parity-violating (PV)
observables is analyzed. A comparison is made between atomic PV for a single
isotope, atomic PV using isotope ratios, and PV electron-hadron and
electron-electron scattering. The complementarity among these observables, as
well as with high-energy processes, is emphasized. Theoretical uncertainties
entering the interpretation of low-energy measurements are discussed.Comment: 37 pages, 2 figures. Omissions to Tables I and V corrected along with
some minor typographical errors. To appear in Phys. Rev.
The PREDICTS database: A global database of how local terrestrial biodiversity responds to human impacts
© 2014 The Authors. Ecology and Evolution published by John Wiley & Sons Ltd. Biodiversity continues to decline in the face of increasing anthropogenic pressures such as habitat destruction, exploitation, pollution and introduction of alien species. Existing global databases of species' threat status or population time series are dominated by charismatic species. The collation of datasets with broad taxonomic and biogeographic extents, and that support computation of a range of biodiversity indicators, is necessary to enable better understanding of historical declines and to project - and avert - future declines. We describe and assess a new database of more than 1.6 million samples from 78 countries representing over 28,000 species, collated from existing spatial comparisons of local-scale biodiversity exposed to different intensities and types of anthropogenic pressures, from terrestrial sites around the world. The database contains measurements taken in 208 (of 814) ecoregions, 13 (of 14) biomes, 25 (of 35) biodiversity hotspots and 16 (of 17) megadiverse countries. The database contains more than 1% of the total number of all species described, and more than 1% of the described species within many taxonomic groups - including flowering plants, gymnosperms, birds, mammals, reptiles, amphibians, beetles, lepidopterans and hymenopterans. The dataset, which is still being added to, is therefore already considerably larger and more representative than those used by previous quantitative models of biodiversity trends and responses. The database is being assembled as part of the PREDICTS project (Projecting Responses of Ecological Diversity In Changing Terrestrial Systems - www.predicts.org.uk). We make site-level summary data available alongside this article. The full database will be publicly available in 2015. The collation of biodiversity datasets with broad taxonomic and biogeographic extents is necessary to understand historical declines and to project - and hopefully avert - future declines. We describe a newly collated database of more than 1.6 million biodiversity measurements from 78 countries representing over 28,000 species, collated from existing spatial comparisons of local-scale biodiversity exposed to different intensities and types of anthropogenic pressures, from terrestrial sites around the world
Where are we now with European forest multi-taxon biodiversity and where can we head to?
The European biodiversity and forest strategies rely on forest sustainable management (SFM) to conserve forest biodiversity. However, current sustainability assessments hardly account for direct biodiversity indicators. We focused on forest multi-taxon biodiversity to: i) gather and map the existing information; ii) identify knowledge and research gaps; iii) discuss its research potential. We established a research network to fit data on species, standing trees, lying deadwood and sampling unit description from 34 local datasets across 3591 sampling units. A total of 8724 species were represented, with the share of common and rare species varying across taxonomic classes: some included many species with several rare ones (e.g., Insecta); others (e.g., Bryopsida) were represented by few common species. Tree-related structural attributes were sampled in a subset of sampling units (2889; 2356; 2309 and 1388 respectively for diameter, height, deadwood and microhabitats). Overall, multi-taxon studies are biased towards mature forests and may underrepresent the species related to other developmental phases. European forest compositional categories were all represented, but beech forests were over-represented as compared to thermophilous and boreal forests. Most sampling units (94%) were referred to a habitat type of conservation concern. Existing information may support European conservation and SFM strategies in: (i) methodological harmonization and coordinated monitoring; (ii) definition and testing of SFM indicators and thresholds; (iii) data-driven assessment of the effects of environmental and management drivers on multi-taxon forest biological and functional diversity, (iv) multi-scale forest monitoring integrating in-situ and remotely sensed information
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