Healthy living in Oregon project

The Institute of Medicine has identified Latino and American Indian populations as populations experiencing significant health and health care access inequities. Previous research indicates that Latinos and American Indians suffer from excess morbidity in respect to same-aged White adults due to higher rates of preventable chronic diseases (i.e. high blood pressure, and diabetes) There are two main objectives of this study: 1. Identify the prominent health-related issues in two Oregon Latino communities and one American Indian community 2. Examine the factors that key informants perceive as enabling or inhibiting healthy lifestyles of community residents

Conceptualization of Autism in the Latino Community and its Relationship with Early Diagnosis

Objective—Early identification of autism spectrum disorders (ASD) has been linked to improved long-term developmental outcomes. However, Latino children are diagnosed later than white non- Latino children. We aimed to qualitatively assess the understanding and conceptualization of ASD in the Latino community in order to understand potential community barriers to early diagnosis. Method—We conducted 5 focus groups and 4 qualitative interviews with 30 parents of typicallydeveloping Latino children in Oregon. Participants were asked structured questions concerning video vignettes that follow a Latina mother from the time she begins to worry about her 3-year-old son\u27s behaviors to the time he receives an ASD diagnosis. Focus groups and interviews were audio-recorded, transcribed and independently coded. Coded data were analyzed using thematic analysis. Results—Many Latino families in the study had not heard of ASD or had little information about it. Families sometimes assumed ASD red flags were normal or could be attributed to family dysfunction. Families also had concerns about provider communication and access to language services. Having a child with a developmental delay was associated with embarrassment, rejection, and family burden, making it difficult for parents to raise developmental concerns with providers. Conclusion—Pediatric providers should not assume that Latino parents have heard of ASD or know its symptoms. Providers should be aware that parents may be reluctant to mention concerns due to cultural factors. The health care system needs to improve resources for Latino parents with limited English proficiency. Policies should encourage the use of developmental screening in primary car

Lung Adenocarcinoma Distally Rewires Hepatic Circadian Homeostasis

The circadian clock controls metabolic and physiological processes through finely tuned molecular mechanisms. The clock is remarkably plastic and adapts to exogenous "zeitgebers," such as light and nutrition. How a pathological condition in a given tissue influences systemic circadian homeostasis in other tissues remains an unanswered question of conceptual and biomedical importance. Here, we show that lung adenocarcinoma operates as an endogenous reorganizer of circadian metabolism. High-throughput transcriptomics and metabolomics revealed unique signatures of transcripts and metabolites cycling exclusively in livers of tumor-bearing mice. Remarkably, lung cancer has no effect on the core clock but rather reprograms hepatic metabolism through altered pro-inflammatory response via the STAT3-Socs3 pathway. This results in disruption of AKT, AMPK, and SREBP signaling, leading to altered insulin, glucose, and lipid metabolism. Thus, lung adenocarcinoma functions as a potent endogenous circadian organizer (ECO), which rewires the pathophysiological dimension of a distal tissue such as the liver

LA PLATAFORMA MOODLE EN EL PROCESO DE ENSEÑANZA APRENDIZAJE DE LOS ESTUDIANTES DE PRIMER AÑO DE LENGUAS EXTRANJERAS INGLÉS DE LA UNIVERSIDAD DE HOLGUIN

Frente a los desafíos de la nueva universidad, con la introducción de las Tecnologías de la Información y las Comunicaciones (TIC), y las crecientes y diversas necesidades de formación en la educación superior se requiere que la misma asuma estrategias educativas que favorezcan la formación de profesionales competentes con el empleo de los recursos educativos puestos a su alcance. La presente investigación parte de la determinación a través de un estudio de diagnóstico, de las insuficiencias que presentan los estudiantes de primer año de la carrera Lenguas Extranjeras Inglés de la Universidad de Holguín en el empleo de la plataforma Moodle. Para ello se parte de la determinación de las principales carencias y sus posibles soluciones para la implementación de acciones de orientación educativa. Como vía de solución al problema se propone la elaboración de acciones de orientación para el empleo de la plataforma Moodle en el proceso de enseñanza aprendizaje, las mismas se fundamentan en las concepciones teóricas de la orientación educativa en el contexto universitario con la mediación de las TIC

Characterization of production systems under an agroforestry systems approach of the middle right bank of the Huallaga river –Aucayacu

El propósito del estudio fue caracterizar los sistemas agroforestales SAF, de la cuenca media margen derecha del río Huallaga - Aucayacu, departamento de Huánuco. A través de encuestas realizada a 16 propietarios se caracterizó y tipificó propiedades demostrativas PD, determinándose tres tipos (pequeños, medianas y grandes) con características socioeconómicas y biofísicas diferentes; donde anteriormente predominaba el cultivo de coca (Erythroxylum coca Lam. y E. novogranatense Morris). Posteriormente se seleccionaron 14 propiedades demostrativas distribuidas en cuatro sectores Maronilla (5), Pucayacu - 7 de octubre (2), Aucayacu (4) Los Milagros (3). Se determinaron siete sistemas de uso de la tierra (bosque, purma, monocultivos, pastos, SAF, y otros). Se identificaron 22 SAF, distribuidos: Maronilla (11), Pucayacu - 7 de octubre (4), Aucayacu (4) y en Los Milagros (3). La densidad de árboles varía de 51 a 80 ha-1. Se encontró una gran diversidad de especies arbóreas; (9) en los SAF de Maronilla, (9) en los SAF de Pucayacu 7 – de Octubre, (29) en los SAF de Aucayacu y (26) en los SAF de Los Milagros. Se determinó tres categorías de uso del componente arbóreo (uso múltiple, energético y frutal), predominan especies de uso múltiple; Maronilla (85%), en Pucayacu - 7 de octubre (59%), en Aucayacu (62%), mientras que en Los Milagros predominan de uso maderables (50%). Se realizó la valorización económica del componente arbóreo encontrándose, que el componente arbóreo de los SAF tiene un valor que sobrepasan a S/. 1´343,63 nuevos soles ha-1

DIRETRIZES PARA OS PROGRAMAS DE USO PÚBLICO DO INSTITUTO FLORESTAL DO ESTADO DE SÃO PAULO - SMA

Elaborou-se as Diretrizes para os Programas de Uso Público do Instituto Florestal do Estado de São Paulo visando normatizar, direcionar e homogeneizar esses programas, orientando-os para um objetivo comum que é o atendimento às populações. As diretrizes ora apresentadas resultam da experiência que o Grupo de Trabalho de Educação Ambiental do Instituto Flores- "tal têm acumulado nos dez anos de sua existência

The radio soap opera as a pedagogical practice for reading learning in primary school

La radionovela es un género radial en desuso con un lenguaje coloquial que conmueve a los oyentes en sus conductas lingüísticas a través de su influencia cotidiana. Cuyo lenguaje puede favorecer el aprendizaje en la comprensión lectora de los estudiantes. El estudio tuvo como propósito implementar la radionovela como práctica pedagógica para el aprendizaje de lectura en básica primaria. Este estuvo guiado bajo los lineamientos metodológicos de la IEP con un diseño basado en las trayectorias de indagación. Se utilizaron técnicas de recolección de datos como; la observación participante y el diario de campo. La población estuvo conformada por cuarenta (40) estudiantes de básica primaria de la IED Cerro Blanco del Municipio de Zona Bananera, Magdalena. Se evidencio que los estudiantes mejoraron su comprensión lectora y por ende su desempeño académico observando que el acompañamiento en casa muchas veces era limitado porque los adultos no sabían leer y a través de la implementación de la radionovela lograron comprender y acompañar a los estudiantes en el proceso de aprendizaje, concluyendo que cualquier acción educativa está compuesta por relaciones sociales, están manifiestan bajo formas pedagógicas aquellas representaciones sociales que son visibles en este género radial.The radionovela is a disused radio genre with a colloquial language that moves the listeners in their linguistic behaviors through their daily influence. Whose language can favor learning in the reading comprehension of students. The purpose of the study was to implement the radionovela as a pedagogical practice for reading learning in elementary school. This was guided under the methodological guidelines of the IEP with a design based on the trajectories of inquiry. Data collection techniques were used, such as; the participant observation and the field diary. The population was conformed by forty (40) primary students of the IED Cerro Blanco of the Municipality of Zona Bananera, Magdalena. It was evidenced that the students improved their reading comprehension and therefore their academic performance observing that the accompaniment at home was often limited because the adults did not know how to read and through the implementation of the radionovela they were able to understand and accompany the students in the process of learning, concluding that any educational action is composed of social relations, are manifested under pedagogical forms those social representations that are visible in this radial genre

COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study

Background: The ISARIC prospective multinational observational study is the largest cohort of hospitalized patients with COVID-19. We present relationships of age, sex, and nationality to presenting symptoms. Methods: International, prospective observational study of 60 109 hospitalized symptomatic patients with laboratory-confirmed COVID-19 recruited from 43 countries between 30 January and 3 August 2020. Logistic regression was performed to evaluate relationships of age and sex to published COVID-19 case definitions and the most commonly reported symptoms. Results: ‘Typical’ symptoms of fever (69%), cough (68%) and shortness of breath (66%) were the most commonly reported. 92% of patients experienced at least one of these. Prevalence of typical symptoms was greatest in 30- to 60-year-olds (respectively 80, 79, 69%; at least one 95%). They were reported less frequently in children (≤ 18 years: 69, 48, 23; 85%), older adults (≥ 70 years: 61, 62, 65; 90%), and women (66, 66, 64; 90%; vs. men 71, 70, 67; 93%, each P < 0.001). The most common atypical presentations under 60 years of age were nausea and vomiting and abdominal pain, and over 60 years was confusion. Regression models showed significant differences in symptoms with sex, age and country. Interpretation: This international collaboration has allowed us to report reliable symptom data from the largest cohort of patients admitted to hospital with COVID-19. Adults over 60 and children admitted to hospital with COVID-19 are less likely to present with typical symptoms. Nausea and vomiting are common atypical presentations under 30 years. Confusion is a frequent atypical presentation of COVID-19 in adults over 60 years. Women are less likely to experience typical symptoms than men