DNS of compressible multiphase flows through the Eulerian approach

In this paper we present three multiphase flow models suitable for the study of the dynamics of compressible dispersed multiphase flows. We adopt the Eulerian approach because we focus our attention to dispersed (concentration smaller than 0.001) and small particles (the Stokes number has to be smaller than 0.2). We apply these models to the compressible ($\text{Ma} = 0.2,\,0.5$) homogeneous and isotropic decaying turbulence inside a periodic three-dimensional box ($256^3$ cells) using a numerical solver based on the OpenFOAM$^{R}$ C++ libraries. In order to validate our simulations in the single-phase case we compare the energy spectrum obtained with our code with the one computed by an eighth order scheme getting a very good result (the relative error is very small $4*10^{-4}$). Moving to the bi-phase case, initially we insert inside the box an homogeneous distribution of particles leaving unchanged the initial velocity field. Because of the centrifugal force, turbulence induce particle preferential concentration and we study the evolution of the solid-phase density. Moreover, we do an {\em a-priori} test on the new sub-grid term of the multiphase equations comparing them with the standard sub-grid scale term of the Navier-Stokes equations.Comment: 10 pages, 5 figures, preprint. Direct and Large Eddy Simulations 9, 201

Stigma and Criminalization of Mental Health in an Inpatient Versus Jail Setting

Stigmatization is the perceived, negative stereotype assigned to a group of individuals. This stigmatization has contributed to the criminalization of mental health, meaning that individuals with mental health issues are more likely to be arrested for behaviors that are not criminal. This project examines mental health stigma toward an individual in a psychiatric setting and a correctional setting. We hypothesized that when reading a vignette about an individual experiencing a mental health crisis, participants will stigmatize them more if they are incarcerated than if they are in a psychiatric facility. Results showed that participants exhibited a higher level of discrimination stigma for the jail condition than for the psychiatric facility condition. This research has important implications for those individuals who are incarcerated, experience mental health issues, and are more susceptible to discriminatory beliefs

Neural Correlates of Fear in the Periaqueductal Gray

International audienceThe dorsal and ventral periaqueductal gray (dPAG and vPAG, respectively) are embedded in distinct survival networks that coordinate, respectively, innate and conditioned fear-evoked freezing. However, the information encoded by the PAG during these survival behaviors is poorly understood. Recordings in the dPAG and vPAG in rats revealed differences in neuronal activity associated with the two behaviors. During innate fear, neuronal responses were significantly greater in the dPAG compared with the vPAG. After associative fear conditioning and during early extinction (EE), when freezing was maximal, a field potential was evoked in the PAG by the auditory fear conditioned stimulus (CS). With repeated presentations of the unreinforced CS, animals displayed progressively less freezing accompanied by a reduction in event-related field potential amplitude. During EE, the majority of dPAG and vPAG units increased their firing frequency, but spike-triggered averaging showed that only ventral activity during the presentation of the CS was significantly coupled to EMG-related freezing behavior. This PAG–EMG coupling was only present for the onset of freezing activity during the CS in EE. During late extinction, a subpopulation of units in the dPAG and vPAG continued to show CS-evoked responses; that is, they were extinction resistant. Overall, these findings support roles for the dPAG in innate and conditioned fear and for the vPAG in initiating but not maintaining the drive to muscles to generate conditioned freezing. The existence of extinction-susceptible and extinction-resistant cells also suggests that the PAG plays a role in encoding fear memories

Measurement of Drift Velocity in the CMS Barrel Muon Chambers at the CMS Magnet Test Cosmic Challenge

This note reports the results of the analysis performed on the data collected by the CMS Barrel Muon system during the Magnet Test-Cosmic Challenge, aimed to study the Drift Tube chambers behavior at the nominal value of the CMS magnetic field. In particular, the analysis is devoted to the study of the drift velocity in the various equipped regions of the apparatus. It is shown that the drift velocity is significantly affected by the presence of a residual magnetic field in the chamber volume only in the innermost stations, MB1, of Wheel+2; where the maximal variation inside the chamber is of 4 percent, which does not prevent a good functionality of the DT trigger even in this most critical region

Simultaneous Continuation of Infinitely Many Sinks Near a Quadratic Homoclinic Tangency

We prove that the $C^3$ diffeomorphisms on surfaces, exhibiting infinitely many sinksnear the generic unfolding of a quadratic homoclinic tangency of a dissipative saddle, can be perturbed along an infinite dimensional manifold of $C^3$ diffeomorphisms such that infinitely many sinks persist simultaneously. On the other hand, if they are perturbed along one-parameter families that unfold generically the quadratic tangencies, then at most a finite number of those sinks have continuation

Sensorimotor, language, and working memory representation within the human cerebellum

The cerebellum is involved in a wide range of behaviours. A key organisational principle from animal studies is that somatotopically corresponding sensory input and motor output reside in the same cerebellar cortical areas. However, compelling evidence for a similar arrangement in humans and whether it extends to cognitive functions is lacking. To address this, we applied cerebellar optimised whole-brain functional MRI in 20 healthy subjects. To assess spatial overlap within the sensorimotor and cognitive domains, we recorded activity to a sensory stimulus (vibrotactile) and a motor task; the Sternberg verbal working memory (VWM) task; and a verb generation paradigm. Consistent with animal data, sensory and motor activity overlapped with a somatotopic arrangement in ipsilateral areas of the anterior and posterior cerebellum. During the maintenance phase of the Sternberg task, a positive linear relationship between VWM load and activity was observed in right Lobule VI, extending into Crus I bilaterally. Articulatory movement gave rise to bilateral activity in medial Lobule VI. A conjunction of two independent language tasks localised activity during verb generation in right Lobule VI-Crus I, which overlapped with activity during VWM. These results demonstrate spatial compartmentalisation of sensorimotor and cognitive function in the human cerebellum, with each area involved in more than one aspect of a given behaviour, consistent with an integrative function. Sensorimotor localisation was uniform across individuals, but the representation of cognitive tasks was more variable, highlighting the importance of individual scans for mapping higher order functions within the cerebellum

Sensory and motor electrophysiological mapping of the cerebellum in humans

Cerebellar damage during posterior fossa surgery in children can lead to ataxia and risk of cerebellar mutism syndrome. Compartmentalisation of sensorimotor and cognitive functions within the cerebellum have been demonstrated in animal electrophysiology and human imaging studies. Electrophysiological monitoring was carried out under general anaesthesia to assess the limb sensorimotor representation within the human cerebellum for assessment of neurophysiological integrity to reduce the incidence of surgical morbidities. Thirteen adult and paediatric patients undergoing posterior fossa surgery were recruited. Sensory evoked field potentials were recorded in response to mapping (n = 8) to electrical stimulation of limb nerves or muscles. For motor mapping (n = 5), electrical stimulation was applied to the surface of the cerebellum and evoked EMG responses were sought in facial and limb muscles. Sensory evoked potentials were found in two patients (25%). Responses were located on the surface of the right inferior posterior cerebellum to stimulation of the right leg in one patient, and on the left inferior posterior lobe in another patient to stimulation of left forearm. No evoked EMG responses were found for the motor mapping. The present study identifies challenges with using neurophysiological methods to map functional organization within the human cerebellum and considers ways to improve success

Search for the standard model Higgs boson in the H to ZZ to 2l 2nu channel in pp collisions at sqrt(s) = 7 TeV

A search for the standard model Higgs boson in the H to ZZ to 2l 2nu decay channel, where l = e or mu, in pp collisions at a center-of-mass energy of 7 TeV is presented. The data were collected at the LHC, with the CMS detector, and correspond to an integrated luminosity of 4.6 inverse femtobarns. No significant excess is observed above the background expectation, and upper limits are set on the Higgs boson production cross section. The presence of the standard model Higgs boson with a mass in the 270-440 GeV range is excluded at 95% confidence level.Comment: Submitted to JHE