La industria automotriz en el estado de Querétaro: ¿cambio estructural?.

Las empresas de autopartes y automotrices tienen una larga historia en Mé- xico. La industria automotriz mexicana ha tenido en las últimas dos décadas una importante expansión en todo el país, a tal grado que en la actualidad aporta más al PIB nacional que varios estados de la República. Debido a la importancia que tiene la industria automotriz para México y para el estado de Querétaro, resulta relevante determinar si la producción manufacturera de este estado y las exportaciones nacionales del sector permanecen estables en el tiempo. El presente estudio tiene como nalidad determinar si la producción y las exportaciones de la industria automotriz de Querétaro fueron afectadas por las perturbaciones externas que experimentó el país. Para poder identi - car si hubo un cambio o no en la industria automotriz, se utilizaron dos mo- delos con dos pruebas distintas de estabilidad estructural, debido a los escasos datos sobre la industria automotriz en el estado. En el análisis de los princi- pales indicadores de producción, de exportación de la industria automotriz y de manufactura, se identi caron claramente tres momentos de la industria: el primero antes de la rma del Tratado de Libre Comercio de América del Nor- te, el segundo es el lapso comprendido entre 1994 y 2007 (periodo previo a la crisis nanciera en los Estados Unidos y Europa) y el tercero es en el que actualmente nos encontramos que abarca de 2008 a la fecha

Talento 360: Potenciar la satisfacción de los estudiantes a través de la evaluación continua y la Gestión del Talento de los Grupos Multigeneracionales (GIMM)

Para mejorar los criterios de satisfacción de los estudiantes de la asignatura se ha creado un Grupo de Iniciativa y Mejora Multidisciplinar y Multigeneracional (GIMM) conformado por estudiantes de diferentes cursos y de doctorado, así como por profesores de diferentes asignaturas. Este grupo tiene por finalidad gestionar el talento de diferentes generaciones en la creación de un Now How que mejore la satisfacción de los estudiantes que cursan la asignatura. Para realizar este proyecto se hace una evaluación en 2 momentos: evaluación inicial y final. Cada evaluación será analizada por el GIMM siguiendo una metodología Focus Group y PDCA. Este grupo propondrá medidas innovadoras de la asignatura para mejorar las puntuaciones en cada una de las evaluaciones de satisfacción. Con el análisis de la evaluación final se realizara un informe de buenas prácticas para conocer los aspectos más importantes a tener en cuenta para impartir una asignatura de calidad

The evolution of the ventilatory ratio is a prognostic factor in mechanically ventilated COVID-19 ARDS patients

Background: Mortality due to COVID-19 is high, especially in patients requiring mechanical ventilation. The purpose of the study is to investigate associations between mortality and variables measured during the first three days of mechanical ventilation in patients with COVID-19 intubated at ICU admission. Methods: Multicenter, observational, cohort study includes consecutive patients with COVID-19 admitted to 44 Spanish ICUs between February 25 and July 31, 2020, who required intubation at ICU admission and mechanical ventilation for more than three days. We collected demographic and clinical data prior to admission; information about clinical evolution at days 1 and 3 of mechanical ventilation; and outcomes. Results: Of the 2,095 patients with COVID-19 admitted to the ICU, 1,118 (53.3%) were intubated at day 1 and remained under mechanical ventilation at day three. From days 1 to 3, PaO2/FiO2 increased from 115.6 [80.0-171.2] to 180.0 [135.4-227.9] mmHg and the ventilatory ratio from 1.73 [1.33-2.25] to 1.96 [1.61-2.40]. In-hospital mortality was 38.7%. A higher increase between ICU admission and day 3 in the ventilatory ratio (OR 1.04 [CI 1.01-1.07], p = 0.030) and creatinine levels (OR 1.05 [CI 1.01-1.09], p = 0.005) and a lower increase in platelet counts (OR 0.96 [CI 0.93-1.00], p = 0.037) were independently associated with a higher risk of death. No association between mortality and the PaO2/FiO2 variation was observed (OR 0.99 [CI 0.95 to 1.02], p = 0.47). Conclusions: Higher ventilatory ratio and its increase at day 3 is associated with mortality in patients with COVID-19 receiving mechanical ventilation at ICU admission. No association was found in the PaO2/FiO2 variation

Treatment with tocilizumab or corticosteroids for COVID-19 patients with hyperinflammatory state: a multicentre cohort study (SAM-COVID-19)

Objectives: The objective of this study was to estimate the association between tocilizumab or corticosteroids and the risk of intubation or death in patients with coronavirus disease 19 (COVID-19) with a hyperinflammatory state according to clinical and laboratory parameters. Methods: A cohort study was performed in 60 Spanish hospitals including 778 patients with COVID-19 and clinical and laboratory data indicative of a hyperinflammatory state. Treatment was mainly with tocilizumab, an intermediate-high dose of corticosteroids (IHDC), a pulse dose of corticosteroids (PDC), combination therapy, or no treatment. Primary outcome was intubation or death; follow-up was 21 days. Propensity score-adjusted estimations using Cox regression (logistic regression if needed) were calculated. Propensity scores were used as confounders, matching variables and for the inverse probability of treatment weights (IPTWs). Results: In all, 88, 117, 78 and 151 patients treated with tocilizumab, IHDC, PDC, and combination therapy, respectively, were compared with 344 untreated patients. The primary endpoint occurred in 10 (11.4%), 27 (23.1%), 12 (15.4%), 40 (25.6%) and 69 (21.1%), respectively. The IPTW-based hazard ratios (odds ratio for combination therapy) for the primary endpoint were 0.32 (95%CI 0.22-0.47; p < 0.001) for tocilizumab, 0.82 (0.71-1.30; p 0.82) for IHDC, 0.61 (0.43-0.86; p 0.006) for PDC, and 1.17 (0.86-1.58; p 0.30) for combination therapy. Other applications of the propensity score provided similar results, but were not significant for PDC. Tocilizumab was also associated with lower hazard of death alone in IPTW analysis (0.07; 0.02-0.17; p < 0.001). Conclusions: Tocilizumab might be useful in COVID-19 patients with a hyperinflammatory state and should be prioritized for randomized trials in this situatio

Search for eccentric black hole coalescences during the third observing run of LIGO and Virgo

Despite the growing number of confident binary black hole coalescences observed through gravitational waves so far, the astrophysical origin of these binaries remains uncertain. Orbital eccentricity is one of the clearest tracers of binary formation channels. Identifying binary eccentricity, however, remains challenging due to the limited availability of gravitational waveforms that include effects of eccentricity. Here, we present observational results for a waveform-independent search sensitive to eccentric black hole coalescences, covering the third observing run (O3) of the LIGO and Virgo detectors. We identified no new high-significance candidates beyond those that were already identified with searches focusing on quasi-circular binaries. We determine the sensitivity of our search to high-mass (total mass M&gt;70 M⊙) binaries covering eccentricities up to 0.3 at 15 Hz orbital frequency, and use this to compare model predictions to search results. Assuming all detections are indeed quasi-circular, for our fiducial population model, we place an upper limit for the merger rate density of high-mass binaries with eccentricities 0&lt;e≤0.3 at 0.33 Gpc−3 yr−1 at 90\% confidence level

Ultralight vector dark matter search using data from the KAGRA O3GK run

Among the various candidates for dark matter (DM), ultralight vector DM can be probed by laser interferometric gravitational wave detectors through the measurement of oscillating length changes in the arm cavities. In this context, KAGRA has a unique feature due to differing compositions of its mirrors, enhancing the signal of vector DM in the length change in the auxiliary channels. Here we present the result of a search for U(1)B−L gauge boson DM using the KAGRA data from auxiliary length channels during the first joint observation run together with GEO600. By applying our search pipeline, which takes into account the stochastic nature of ultralight DM, upper bounds on the coupling strength between the U(1)B−L gauge boson and ordinary matter are obtained for a range of DM masses. While our constraints are less stringent than those derived from previous experiments, this study demonstrates the applicability of our method to the lower-mass vector DM search, which is made difficult in this measurement by the short observation time compared to the auto-correlation time scale of DM

La industria automotriz en el estado de Querétaro: ¿cambio estructural?.

Las empresas de autopartes y automotrices tienen una larga historia en Mé- xico. La industria automotriz mexicana ha tenido en las últimas dos décadas una importante expansión en todo el país, a tal grado que en la actualidad aporta más al PIB nacional que varios estados de la República. Debido a la importancia que tiene la industria automotriz para México y para el estado de Querétaro, resulta relevante determinar si la producción manufacturera de este estado y las exportaciones nacionales del sector permanecen estables en el tiempo. El presente estudio tiene como nalidad determinar si la producción y las exportaciones de la industria automotriz de Querétaro fueron afectadas por las perturbaciones externas que experimentó el país. Para poder identi - car si hubo un cambio o no en la industria automotriz, se utilizaron dos mo- delos con dos pruebas distintas de estabilidad estructural, debido a los escasos datos sobre la industria automotriz en el estado. En el análisis de los princi- pales indicadores de producción, de exportación de la industria automotriz y de manufactura, se identi caron claramente tres momentos de la industria: el primero antes de la rma del Tratado de Libre Comercio de América del Nor- te, el segundo es el lapso comprendido entre 1994 y 2007 (periodo previo a la crisis nanciera en los Estados Unidos y Europa) y el tercero es en el que actualmente nos encontramos que abarca de 2008 a la fecha

Comment on: “Assessment of Skeletal Muscle Contractile Properties by Radial Displacement: The Case for Tensiomyography”

Sin financiación8.551 JCR (2019) Q1, 2/85 Sport Sciences3.29 SJR (2019) Q1, 2/207 Physical Therapy, Sports Therapy and Rehabilitation, 3/125 Sports Science, 59/2754 Medicine (miscellaneous), 2/284 2754 Medicine (miscellaneous)No data IDR 2019UE

Enhancement of Mood but not Performance in Elite Athletes With Transcranial Direct-Current Stimulation

To determine if transcranial direct-current stimulation (tDCS) could be effective for the enhancement of swimming performance or mood state in elite athletes. Methods: Eight male elite triathletes (age = 20 [2] y, maximal oxygen uptake = 71 [4] mL·kg−1·min−1) participated in this crossover, counterbalanced, sham-controlled, double-blind study. Participants received either actual (20 min of anodal stimulation of the motor cortex at 2 mA) or sham tDCS and performed an 800-m swimming test in which rating of perceived exertion and blood lactate response were measured. Mood state (Brunel Mood Scale) was assessed before and after each tDCS session and after the swimming test. Heart-rate variability and central nervous system readiness were assessed before and after each tDCS session. The chances of finding differences between conditions were determined using magnitude-based inferences. Results: A significant and very likely higher Brunel Mood Scale–determined vigor self-perception was found with actual tDCS after the stimulation session (−0.1 [1.2] and 2.0 [2.3] for sham and actual tDCS, respectively; P = .018, effect size = 1.14) and after exercise (−4.1 [2.9] and −0.9 [3.6] for sham and actual tDCS, respectively; P = .022, effect size = 0.98). However, likely trivial and nonsignificant (P > .05) differences were found between conditions in performance (599 [38] s and 596 [39] s, respectively). Unclear and nonsignificant differences were observed between conditions for the rest of the study end points. Conclusions: tDCS elicited a marked increase in vigor self-perception that was maintained after exercise but failed to improve swimming performance in elite triathletes.Sin financiación3.528 JCR (2019) Q1, 13/85 Sport Sciences, 17/81 Physiology1.78 SJR (2019) Q1, 6/207 Physical Therapy, Sports Therapy and Rehabilitation, 11/125 Sports Science, 13/284 Orthopedics and Sports MedicineNo data IDR 2019UE