1,481 research outputs found
Workshop on Mars Sample Return Science
Martian magnetic history; quarantine issues; surface modifying processes; climate and atmosphere; sampling sites and strategies; and life sciences were among the topics discussed
Conceptual Design of the Coronagraphic High Angular Resolution Imaging Spectrograph (CHARIS) for the Subaru Telescope
Recent developments in high-contrast imaging techniques now make possible
both imaging and spectroscopy of planets around nearby stars. We present the
conceptual design of the Coronagraphic High Angular Resolution Imaging
Spectrograph (CHARIS), a lenslet-based, cryogenic integral field spectrograph
(IFS) for imaging exoplanets on the Subaru telescope. The IFS will provide
spectral information for 140x140 spatial elements over a 1.75 arcsecs x 1.75
arcsecs field of view (FOV). CHARIS will operate in the near infrared (lambda =
0.9 - 2.5 microns) and provide a spectral resolution of R = 14, 33, and 65 in
three separate observing modes. Taking advantage of the adaptive optics systems
and advanced coronagraphs (AO188 and SCExAO) on the Subaru telescope, CHARIS
will provide sufficient contrast to obtain spectra of young self-luminous
Jupiter-mass exoplanets. CHARIS is in the early design phases and is projected
to have first light by the end of 2015. We report here on the current
conceptual design of CHARIS and the design challenges
The Optical Design of CHARIS: An Exoplanet IFS for the Subaru Telescope
High-contrast imaging techniques now make possible both imaging and
spectroscopy of planets around nearby stars. We present the optical design for
the Coronagraphic High Angular Resolution Imaging Spectrograph (CHARIS), a
lenslet-based, cryogenic integral field spectrograph (IFS) for imaging
exoplanets on the Subaru telescope. The IFS will provide spectral information
for 138x138 spatial elements over a 2.07 arcsec x 2.07 arcsec field of view
(FOV). CHARIS will operate in the near infrared (lambda = 1.15 - 2.5 microns)
and will feature two spectral resolution modes of R = 18 (low-res mode) and R =
73 (high-res mode). Taking advantage of the Subaru telescope adaptive optics
systems and coronagraphs (AO188 and SCExAO), CHARIS will provide sufficient
contrast to obtain spectra of young self-luminous Jupiter-mass exoplanets.
CHARIS will undergo CDR in October 2013 and is projected to have first light by
the end of 2015. We report here on the current optical design of CHARIS and its
unique innovations.Comment: 15 page
Valosin-containing protein (VCP/p97) plays a role in the replication of West Nile virus
Valosin-containing protein (VCP) is classified as a member of the type II AAA(+) ATPase protein family. VCP functions in several cellular processes, including protein degradation, membrane fusion, vesicular trafficking and disassembly of stress granules. Moreover, VCP is considered to play a role in the replication of several viruses, albeit through different mechanisms. In the present study, we have investigated the role of VCP in West Nile virus (WNV) infection. Endogenous VCP expression was inhibited using either VCP inhibitors or by siRNA knockdown. It could be shown that the inhibition of endogenous VCP expression significantly inhibited WNV infection. The entry assay revealed that silencing of endogenous VCP caused a significant reduction in the expression levels of WNV-RNA compared to control siRNA-treated cells. This indicates that VCP may play a role in early steps either the binding or entry steps of the WNV life cycle. Using WNV virus like particles and WNV-DNA-based replicon, it could be demonstrated that perturbation of VCP expression decreased levels of newly synthesized WNV genomic RNA. These findings suggest that VCP is involved in early steps and during genome replication of the WNV life cycle
OH yields from the CH3CO+O-2 reaction using an internal standard
Laser flash photolysis of CH3C(O)OH at 248 nm was used to create equal zero time yields of CH3CO and OH. The absolute OH yield from the CH3CO + O2 (+M) reaction was determined by following the OH temporal profile using the zero time
OH concentration as an internal standard. The OH yield from CH3CO + O2 (+M) was observed to decrease with increasing pressure with an extrapolated zero pressure yield
close to unity (1.1 ± 0.2, quoted uncertainties correspond to 95% confidence limits). The results are in quantitative agreement with those obtained from 248 nm acetone
photolysis in the presence of O2
International cooperation for Mars exploration and sample return
The National Research Council's Space Studies Board has previously recommended that the next major phase of Mars exploration for the United States involve detailed in situ investigations of the surface of Mars and the return to earth for laboratory analysis of selected Martian surface samples. More recently, the European space science community has expressed general interest in the concept of cooperative Mars exploration and sample return. The USSR has now announced plans for a program of Mars exploration incorporating international cooperation. If the opportunity becomes available to participate in Mars exploration, interest is likely to emerge on the part of a number of other countries, such as Japan and Canada. The Space Studies Board's Committee on Cooperative Mars Exploration and Sample Return was asked by the National Aeronautics and Space Administration (NASA) to examine and report on the question of how Mars sample return missions might best be structured for effective implementation by NASA along with international partners. The committee examined alternatives ranging from scientific missions in which the United States would take a substantial lead, with international participation playing only an ancillary role, to missions in which international cooperation would be a basic part of the approach, with the international partners taking on comparably large mission responsibilities. On the basis of scientific strategies developed earlier by the Space Studies Board, the committee considered the scientific and technical basis of such collaboration and the most mutually beneficial arrangements for constructing successful cooperative missions, particularly with the USSR
Separate Universes Do Not Constrain Primordial Black Hole Formation
Carr and Hawking showed that the proper size of a spherical overdense region
surrounded by a flat FRW universe cannot be arbitrarily large as otherwise the
region would close up on itself and become a separate universe. From this
result they derived a condition connecting size and density of the overdense
region ensuring that it is part of our universe. Carr used this condition to
obtain an upper bound for the density fluctuation amplitude with the property
that for smaller amplitudes the formation of a primordial black hole is
possible, while larger ones indicate a separate universe. In contrast, we find
that the appearance of a maximum is not a consequence of avoiding separate
universes but arises naturally from the geometry of the chosen slicing. Using
instead of density a volume fluctuation variable reveals that a fluctuation is
a separate universe iff this variable diverges on superhorizon scales. Hence
Carr's and Hawking's condition does not pose a physical constraint on density
fluctuations. The dynamics of primordial black hole formation with an initial
curvature fluctuation amplitude larger than the one corresponding to the
maximum density fluctuation amplitude was previously not considered in detail
and so we compare it to the well-known case where the amplitude is smaller by
presenting embedding and conformal diagrams of both types in dust spacetimes.Comment: Updated version corresponds to the published version
10.1103/PhysRevD.83.124025, 22 pages, 22 figure
Tick Haller\u27s Organ, a New Paradigm for Arthropod Olfaction: How Ticks Differ from Insects
Ticks are the vector of many human and animal diseases; and host detection is critical to this process. Ticks have a unique sensory structure located exclusively on the 1st pairs of legs; the fore-tarsal Haller\u27s organ, not found in any other animals, presumed to function like the insect antennae in chemosensation but morphologically very different. The mechanism of tick chemoreception is unknown. Utilizing next-generation sequencing and comparative transcriptomics between the 1st and 4th legs (the latter without the Haller\u27s organ), we characterized 1st leg specific and putative Haller\u27s organ specific transcripts from adult American dog ticks, Dermacentor variabilis. The analysis suggested that the Haller\u27s organ is involved in olfaction, not gustation. No known odorant binding proteins like those found in insects, chemosensory lipocalins or typical insect olfactory mechanisms were identified; with the transcriptomic data only supporting a possible olfactory G-protein coupled receptor (GPCR) signal cascade unique to the Haller\u27s organ. Each component of the olfactory GPCR signal cascade was identified and characterized. The expression of GPCR, Gαo and β-arrestin transcripts identified exclusively in the 1st leg transcriptome, and putatively Haller\u27s organ specific, were examined in unfed and blood-fed adult female and male D. variabilis. Blood feeding to repletion in adult females down-regulated the expression of all three chemosensory transcripts in females but not in males; consistent with differences in post-feeding tick behavior between sexes and an expected reduced chemosensory function in females as they leave the host. Data are presented for the first time of the potential hormonal regulation of tick chemosensation; behavioral assays confirmed the role of the Haller\u27s organ in N,N-diethyl-meta-toluamide (DEET) repellency but showed no role for the Haller\u27s organ in host attachment. Further research is needed to understand the potential role of the GPCR cascade in olfaction
Magnetic Dipole Absorption of Radiation in Small Conducting Particles
We give a theoretical treatment of magnetic dipole absorption of
electromagnetic radiation in small conducting particles, at photon energies
which are large compared to the single particle level spacing, and small
compared to the plasma frequency. We discuss both diffusive and ballistic
electron dynamics for particles of arbitrary shape.
The conductivity becomes non-local when the frequency is smaller than the
frequency \omega_c characterising the transit of electrons from one side of the
particle to the other, but in the diffusive case \omega_c plays no role in
determining the absorption coefficient. In the ballistic case, the absorption
coefficient is proportional to \omega^2 for \omega << \omega_c, but is a
decreasing function of \omega for \omega >> \omega_c.Comment: 25 pages of plain TeX, 2 postscipt figure
- …