Produtividade e característica tecnológica de grãos em feijoeiro adubado com nitrogênio e molibdênio

The objective of this work was to evaluate the effect of nitrogen and molybdenum fertilization on the yield and technological characteristics of common bean. The experiment was carried out in a randomized blocks design, in a factorial outline of 4x2, constituted by nitrogen side-dressing levels (0, 30, 60 and 120 kg ha-1), with or without molybdenum leaf application (0 and 80 kg ha-1), with four replications. The Pérola cultivar was sowed in growing season, in no-tillage system. The nitrogen side-dressing and molybdenum application do not affect common bean yield, but influence the technological characteristic of the grains. The protein content, the coocking time, and time for maximum hydration increase with nitrogen side-dressing levels increment. The cocking time is high for nitrogen side-dressing with molybdenum use. The use of molybdenum promotes the maximum grain hydration in the minimum time.O objetivo deste trabalho foi avaliar o efeito da adubação com nitrogênio e molibdênio, na produtividade e nas características tecnológicas dos grãos de feijão. O delineamento utilizado foi o de blocos ao acaso, em esquema fatorial 4x2, constituído por doses de nitrogênio em cobertura (0, 30, 60 e 120 kg ha-1), aliado à aplicação ou não de molibdênio por via foliar (0 e 80 g ha-1), com quatro repetições. A semeadura do feijão, cultivar Pérola, foi realizada em condições de sequeiro e no sistema de plantio direto. A adubação nitrogenada em cobertura e a molíbdica via foliar não influenciam a produtividade, mas interferem na característica tecnológica dos grãos de feijão. O teor de proteína bruta, o tempo de cozimento e o tempo para a máxima hidratação dos grãos aumentam com as doses de nitrogênio em cobertura. O tempo de cozimento é maior, à medida que há incremento de nitrogênio aplicado em cobertura, com uso de molibdênio via foliar. O uso de molibdênio via foliar proporciona o menor tempo para a máxima hidratação de grãos

Smp38 MAP Kinase Regulation in Schistosoma mansoni: Roles in Survival, Oviposition, and Protection Against Oxidative Stress

Eukaryotic protein kinases (ePKs) are good medical targets for drug development in different biological systems. ePKs participate in many cellular processes, including the p38 MAPK regulation of homeostasis upon oxidative stress. We propose to assess the role of Smp38 MAPK signaling pathway in Schistosoma mansoni development and protection against oxidative stress, parasite survival, and also to elucidate which target genes have their expression regulated by Smp38 MAPK. After a significant reduction of up to 84% in the transcription level by Smp38 MAPK gene knockdown, no visible phenotypic changes were reported in schistosomula in culture. The development of adult worms was tested in vivo in mice infected with the Smp38 knocked-down schistosomula. It was observed that Smp38 MAPK has an essential role in the transformation and survival of the parasites as a low number of adult worms was recovered. Smp38 knockdown also resulted in decreased egg production, damaged adult worm tegument, and underdeveloped ovaries in females. Furthermore, only ~13% of the eggs produced developed into mature eggs. Our results suggest that inhibition of the Smp38 MAPK activity interfere in parasites protection against reactive oxygen species. Smp38 knockdown in adult worms resulted in 80% reduction in transcription levels on the 10th day, with consequent reduction of 94.4% in oviposition in vitro. In order to search for Smp38 MAPK pathway regulated genes, we used an RNASeq approach and identified 1,154 DEGs in Smp38 knockdown schistosomula. A substantial proportion of DEGs encode proteins with unknown function. The results indicate that Smp38 regulates essential signaling pathways for the establishment of parasite homeostasis, including genes related to antioxidant defense, structural composition of ribosomes, spliceosomes, cytoskeleton, as well as, purine and pyrimidine metabolism pathways. Our data show that the Smp38 MAPK signaling pathway is a critical route for parasite development and may present attractive therapeutic targets for the treatment and control of schistosomiasis

Effect of Conjugated Linoleic Acid on Memory and Reflex Maturation in Rats Treated During Early Life

In the critical period of neurodevelopment (gestation and lactation), maternal consumption of essential fatty acids (FAs) can alter the offspring cognitive function permanently causing damage. Lipids can regulate neurotrophin and compose brain tissue. However, the effects of maternal consumption of a mixture of conjugated linoleic acid (CLA) on an offspring nervous system are not completely clear. We aimed to investigate the impacts of different CLA concentrations mixed into the maternal diet during early life on neonatal reflex maturation and cognitive functions of the offspring. Three groups were formed: control (CG): receiving a standard diet; CLA1: receiving a diet containing 1% of CLA, and CLA3: receiving a diet containing 3% of CLA, offered during gestation and lactation. After birth, the reflex responses of the offspring were observed from the 1st to the 21st day. After weaning, the animals’ anxiety and memory were assessed using open field (OF) and novel object recognition tests. Fatty acids in the breast milk and the offspring’s brain were also quantified. The data were analyzed using one-way ANOVA and the Kruskal–Wallis test. CLA1 presented accelerated palmar grasp disappearance versus CLA3 and negative-geotaxis versus CG; and the CLA3 presented increases for most reflexes (cliff-avoidance, vibrissa-placing, negative-geotaxis, and auditory-startle response), and decrease in reflexes palmar grasp and free-fall righting versus CG (p < 0.05). CLA3 group explored less of the OF in the second exposure. CLA1 and CLA3 presented an increased exploration ratio for new objects, which indicates memory improvement. The milk tested from CLA3 demonstrated an increase in polyunsaturated fatty acids (PUFAs), and a decrease in monounsaturated fatty acids. The amount of CLA in milk was greater in CLA1 and CLA3 and in the brain offspring both presented moderated amounts of CLA. Maternal treatment with the CLA mixture induced anticipated reflex maturation and improved memory in the offspring. Even though CLA was detected in the brains in only trace amounts, offspring’s brain PUFA and SFA levels were increased. Further studies aimed to delineate the effect of maternal CLA supplementation on offspring’s brain lipid metabolism and long-term neurologic outcome are needed to confirm these findings

Da fotografia como arte à arte como fotografia: a experiência do Museu de Arte Contemporânea da USP na década de 1970

Este ensaio visa sistematizar os primeiros resultados de uma pesquisa, ainda em curso, sobre o processo de legitimação da fotografia pelo sistema de arte no Brasil, cujo foco principal é o museu. Os museus de arte da cidade de São Paulo foram escolhidos para dar início a essa investigação. Primeiramente, será abordada, em linhas gerais, a presença da fotografia no Museu de Arte Moderna de São Paulo e na Bienal de São Paulo, dada a vinculação de origem do Museu de Arte Contemporânea com essas duas instituições paulistanas. Na seqüência será analisada a formação do acervo fotográfico do Museu de Arte Contemporânea da Universidade de São Paulo durante a década de 1970. Por fim, esse percurso permitirá observar que a atuação de Walter Zanini, o primeiro diretor do Museu, e as particularidades da posição do MAC-USP no sistema de arte no Brasil naquele período resultaram no entendimento da fotografia prioritariamente no âmbito da arte contemporânea de caráter experimental e não como obra de arte autônoma, segundo os princípios da chamada fotografia artística.This article presents the first findings of a research still under development about the process of legitimation of photography as a kind of art by the artistic scene in Brazil. The art museums of the city of São Paulo were chosen for starting that research. Initially, we will be investigating the presence of photography at the Contemporary Art Museum of São Paulo and at the Biennial of São Paulo, as the origin of the Contemporary Art Museum is tided to those two institutions. Following, the arrangement of the photographic technical reserve of the Contemporary Art Museum in the 1970s will be analyzed. This study will be focusing on the work of Walter Zanini, as the first director of the museum, and on the particularities of MAC-USP position in the art system in Brazil which resulted in the understanding of photography as belonging to the sphere of contemporary art in an experimental way and not as an autonomous work of art, according to the principals of the so called artistic photography

Caderno de pós-graduação em direito: novas tendências do direito ambiental

Pioneirismo sempre foi uma característica do UniCEUB; outra característica é a evolução permanente. A Instituição sempre acompanhou a evolução tecnológica e pedagógica do ensino. Isso se coaduna com a filosofia institucional que é a de preparar o homem integral por meio da busca do conhecimento e da verdade, assegurando-lhe a compreensão adequada de si mesmo e de sua responsabilidade social e profissional. Destarte, a missão institucional é a de gerar, sistematizar e disseminar o conhecimento visando à formação de cidadãos reflexivos e empreendedores, comprometidos com o desenvolvimento socioeconômico sustentável. E não poderia ser diferente. Com a expansão do conteúdo acadêmico que se transpassa do físico para o virtual, do local para o universal, do restrito para o difundido, isso porque o papel não é mais apenas uma substância constituída por elementos fibrosos de origem vegetal, os quais formam uma pasta que se faz secar sob a forma de folhas delgadas donde se cria, modifica, transforma letras em palavras; palavras em textos; textos em conhecimento, não! O papel se virtualiza, se desenvolve, agora, no infinito, rebuscado de informações. Assim, o UniCEUB acompanha essa evolução. É dessa forma que se desafia o leitor a compreender a atualidade, com a fonte que ora se entrega à leitura virtual, chamada de e-book. Isso é resultado do esforço permanente, da incorporação da ciência desenvolvida no ambiente acadêmico, cujo resultado desperta emoção, um sentimento de beleza de que o conteúdo científico representa o diferencial profissional. Portanto, convido-os a leitura desta obra, que reúne uma sucessão de artigos que são apresentados com grande presteza e maestria; com conteúdo forte e impactante; com sentimento e método, frutos da excelência acadêmicaOrganizadores: Gabriel R. Rozendo Pinto, Leandro Soares Nunes, Naiara Ferreira Martins, Paulo Victor Lima, Pedro Almeida Costa, Pietro Pimenta, Rodrigo Gonçalves Ramos de Oliveir

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio