28 research outputs found
The association between bullying-related behaviours and subjective health complaints in late adolescence: cross-sectional study in Greece
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#NotOkay: Stories About Abuse on Instagram and Twitter
Social media platforms like Twitter and Instagram have recently been used as venues for discussing abusive relationships and sexual violence. This study examines the ways in which social media users and how Twitter and Instagram users engaged with these posts by analyzing 500 Twitter and 500 Instagram posts focused on #NotOkay using a quantitative content analysis. There were marked differences between the posts on the two platforms as well as between engagement with these posts: Instagram overall elicited a higher median level of engagement than Twitter as well as more frequent expressions of social support; in addition, #NotOkay posts on Instagram were more likely to focus on specific acts of sexual assault. On Twitter, posts that included expressions of instrumental social support produced higher engagement. However, mentioning sexual assault produced higher engagement on both platforms. Providers and other interacting with sexual assault survivors should be aware of how these types of violence may be framed and expressed by different populations on different social media platforms
COVID-19 Pandemic and Intimate Partner Violence: an Analysis of Help-Seeking Messages in the Spanish-Speaking Media
The essential role of hippocampal alpha6 subunit-containing GABAA receptors in maternal separation stress-induced adolescent depressive behaviors
In vitro degradation and biocompatibility evaluation of fully biobased thermoplastic elastomers consisting of poly(β-myrcene) and poly( -lactide) as stent coating
The function of myths about great leaders in human culture: A cultural evolutionary perspective
Prevalence, Risk Indicators and Outcomes of Bullying Among On-Reserve First Nations Youth
The Hammerhead Ribozyme
The hammerhead ribozyme has long been considered a prototype for understanding RNA catalysis, but discrepancies between the earlier crystal structures of a minimal hammerhead self-cleaving motif and various biochemical investigations frustrated attempt to understand hammerhead ribozyme catalysis in terms of structure. With the discovery that a tertiary contact distal from the ribozyme’s active site greatly enhances its catalytic prowess, and the emergence of new corresponding crystal structures of full-length hammerhead ribozymes, a unified understanding of catalysis in terms of the structure is now possible. A mechanism in which the invariant residue G12 functions as a general base, and the 2′-OH moiety of the invariant G8, itself forming a tertiary base pair with the invariant C3, is the general acid, appears consistent with both the crystal structure and biochemical experimental results. Originally discovered in the context of plant satellite RNA viruses, the hammerhead more recently has been found embedded in the 3′-untranslated region of mature mammalian mRNAs, suggesting additional biological roles in genetic regulation