481 research outputs found
Dynamic layout algorithms for wireless field hockey strategy system
Sensor deployment in the field of sports is providing enormous potential for elevating the playing field standards. This paper presents an enhanced localization algorithm which harnesses the dynamic and reconfiguration attributes of field hockey players on a strategy board; known as the Wireless Field Hockey Strategy System (WiHoc Ver1.0). The proposed algorithm utilized for determining the location of field hockey players overcomes the constraints and confined anchor based WiHoc Ver 1.0. The resolution encompasses the new versatile platform which captures the positional location within the parameters of a hockey pitch and of cooperative nodes to determine the optimal location of anchor positioning to ensure that the achieved accuracy of localization is enhanced. The proposed algorithm was evaluated extensively through discrete - event simulations. The acquired results via the accuracy performance metrics validated the enhanced ability of the proposed algorithm
Improving Learning Quality Through NHT Cooperation Model in Indonesian Vocational Schools
One of the objectives of cooperative learning is to improve student performance in academic tasks and improve student learning outcomes. This research uses action research method from Kemmis & Taggart with vocational student respondents. Student activity during Total Numbered Heads Together cooperative learning works better, and teacher-run teaching activities are significantly improved. Thus, the mastery of learning can be achieved by applying cooperative learning model type Numbered Heads Together. Student response in this cooperative learning is positive, students enjoy the learning process and are motivated to collaborate during the learning process.
Keywords: cooperative learning, Numbered Heads Togethe
Open Partial Nephrectomy in the Management of Small Renal Masses
Introduction. Most of the kidney masses are being detected incidentally with smaller size due to widespread use of imaging modalities leading to increased RCC incidence worldwide with an earlier stage. This article reviews the role of open partial nephrectomy (PN) in the management of small renal masses. Material and Methods. Review of the English literature using MEDLINE has been performed between 1963–2008 on small renal masses, partial nephrectomy, kidney cancer, nephron sparing surgery (NSS), radical nephrectomy, laparoscopy, and surgical management. Special emphasis was given on the indications of NSS, oncological outcomes and comparison with open and laparoscopic PN. Results. Overall 68 articles including 31 review papers, 35 human clinical papers, 1 book chapter, and 1 animal research study were selected for the purpose of this article and were reviewed by the authors. Conclusions. Currently, open NSS still remains as the gold standard surgical treatment modality in patients with small renal masses
Современные подходы к лечению почечно-клеточного рака
Surgery is the only effective method for the treatment of localized renal cell carcinoma (RCC). Today nephron sparing surgery (NSS) cures the majority of patients with early stage disease. Open radical nephrectomy (RN) is performed mainly in patients with large tumors and in cases complicated by the tumor thrombus extension into the vena cava. Laparoscopy is now more and more often used for RCC treatment. Laparoscopic RN (LRN) is now recommended for the treatment of early stage RCC, when NSS cannot be used. LRN seems to provide longterm cancer control comparable to open RN. RCC is now often diagnosed when the tumors are still small and can be often cured by NSS providing excellent local cancer control. Tumor size, location, multiple foci, surgical margin, and pathological variants are significant for cancer outcome in selective NSS. Laparoscopic partial nephrectomy (LPN) is now gaining popularity as an effective minimally invasive treatment in patients with relatively small and peripheral renal tumors. Recently minimally invasive ablative techniques were introduced for the treatment of RCC. These methods involve little complications if used for the treatment of small renal tumors. The currently used best therapy for metastatic RCC is inadequate and surgery is an important component of combined treatment including immunochemotherapy. Combinations of interferon-alpha, interleukin-2, and 5-fluorouracyl are now used for the treatment of metastatic RCC. Nephrectomy can be recommended for patients with good performance status before immunotherapy. Modern research is focused on identification of novel agents and treatment modalities with better antitumor activity.
Comparing Rawlsian Justice and the Capabilities Approach to Justice from a Spiritually Sensitive Social Work Perspective
‘This is an electronic version of an article published in the March, 2012 special issue of the Journal of Religion and Spirituality and Social Work entitled Spirituality and Social Justice volume 31, (1-2), pp. 9-31. It is available online at
http://dx.doi.org/10.1080/15426432.2012.647874This article examines two social justice theories, Rawlsian Justice and the Capabilities Approach of Sen and Nussbaum, in relation to congruence with four principles of spiritually sensitive social work. We find that although Rawlsian justice has valuable insights, it has some gaps for promoting spiritually sensitive practice. In contrast, the Capabilities Approach bears more promise for promoting spiritually sensitive social work as it meets all these ethical principles. Scholars could build on its insights to articulate a vision for spiritually sensitive social justice that can guide our profession’s approaches to macro practice and social polic
MOLUSCOS DE LA CUENCA DEL RÍO PUNTA GORDA, CARIBE SUR, NICARAGUA, CENTROAMÉRICA
This study is an initial evaluation of mollusk biodiversity in the Punta Gorda River basin, during both the 2013 rainy season and the 2014 dry season at eight locations of land, fluvial and coastal habitats. A total of 127 species were collected (62 terrestrials, 18 fluvial and 47 coastal). Field specimens in good part, mostly Mesoamerican endemics, show preference for undisturbed areas. Freshwater species located in swamps or temporarily flooded terrain, are in risk of disappearing due to actual land use. More research must be given to coastal mollusks on account of their ancestral alimentary value for the Rama communities established along the South Caribbean shore.El presente estudio muestra la línea base de la biodiversidad de moluscos en la cuenca del Río Punta Gorda, encontrada en dos campañas de muestreo, una en la estación lluviosa del 2013 y la otra en la seca del 2014, en ocho sitios con ecosistemas terrestres, dulceacuícolas y marino/costeros. El resultado fue una lista de 127 especies (62 terrestres, 18 acuícolas y 47 marino/costeras). De las terrestres, se presenta un grupo que parece presentar preferencia por áreas poco intervenidas, la mayor parte endémicas de la región centroamericana. Las dulceacuícolas encontradas en pantanos o áreas temporalmente inundadas están en riesgo debido a los usos actuales en la cuenca. En cuanto a las marino/costeras, se requiere más investigación dado su valor alimenticio ancestral para las comunidades de la etnia Rama, asentadas a lo largo del Caribe Sur
Spain's Budget Neglects Research
Letter.-- Carlos Fenollosa et al.Peer Reviewe
Sugar bislactones by one-step oxidative dimerisation with pyridinium chlorochromate versus regioselective oxidation of vicinal diols
Synthesis of 10-membered bislactones by PCC oxidation of methyl 2,6-di-O-pivaloyl-α-D-glucopyranoside and methyl 4,6-O-benzylidene-α-D-glucopyranoside is described, with emphasis on their structure elucidation using the information gained by combination of NMR spectroscopic techniques with X-ray diffraction data. In alternative, the use of PCC and PCC adsorbed on silica gel or alumina for the regioselective oxidation of vicinal diols in sugars is also reported. Both bislactones showed antifungal activity against Candida albicans, and were slightly active against the bacteria Bacillus subtilis. The bislactone presenting pivaloyl protecting groups also promoted some growth inhibition of Staphylococcus aureus.info:eu-repo/semantics/publishedVersio
“Ghosts from the past”: The re-emergence of internalised religious stigma following diagnosis of HIV among Northern Irish gay men
This paper explores how previous exposure to religious homo-negativity features in the sense making process following HIV diagnosis in a homogenous sample of six gay men living in Northern Ireland. Interpretive Phenomenological Analysis was used to identify two key overarching themes: ‘Negotiating authenticity in unsafe space’ which relates to the experience of negotiating same sex attraction within religious environments and ‘Re-emergence of religious shame in diagnosis’ which relates to the way in which the men made sense of diagnosis from the position of having been exposed to religious homo-negativity earlier in their lives. Findings demonstrate how the men negotiated their sexual orientation within religious contexts and how a reconstruction of God was necessary to preserve an authentic sense of self. Despite reaching reconciliation, HIV was initially appraised within a retributive religious framework that served to temporarily reinforce previously learned shame-based models of understanding this aspect of the self
A single-center observational study on long-term neurodevelopmental outcomes in children with tuberous sclerosis complex
Abstract
Background
Tuberous sclerosis complex (TSC) is a rare multisystem disorder caused by mutations in the TSC1 or TSC2 gene. More than 90% of patients with TSC develop neurological and/or neuropsychiatric manifestations. The aim of the present study was to determine the developmental and cognitive long-term outcomes of pediatric TSC patients.
Methods
This cross-sectional, monocenter study included pediatric TSC patients who received multidisciplinary long-term care with a last visit between 2005 and 2019. Neurological manifestations and cognitive development (BSID, K-ABC) were analyzed in relation to age and type of mutation.
Results
Thirty-five patients aged 13.5 ± 7.8 years were included in the study. Diagnosis was confirmed genetically in 65.7% of patients (TSC1, 26.1%; TSC2, 65.2%; NMI, 8.7%). Mean age at diagnosis was 1.3 ± 3.5 years; 74.3% of the patients had been diagnosed within the first year of life due to seizures (62.9%) or/and cardiac rhabdomyomas (28.6%). The most common TSC manifestations included structural brain lesions (cortical tubers, 91.4%; subependymal nodules, 82.9%), epilepsy (85.7%), and cardiac rhabdomyomas (62.9%). Mean age at seizure onset was 1.5 ± 2.3 years, with onset in 80.0% of patients within the first two years of life. Infantile spasms, which were the first seizure type in 23.3% of the patients, developed earlier (0.6 ± 0.4 years) than focal seizures (1.8 ± 2.5 years). Refractory epilepsy was present in 21 (70.0%) patients, mild or severe intellectual impairment in 66.6%, and autism spectrum disorders in 11.4%. Severe cognitive impairment (33.3%) was significantly associated with epilepsy type and age at seizure onset (p < 0.05).
Conclusions
The results emphasized the phenotypic variability of pediatric-onset TSC and the high rate of neurological and neuropsychiatric morbidity. Early-onset refractory epilepsy was associated with impaired cognitive development. Children of all ages with TSC require multidisciplinary long-term care and individual early-intervention programs.
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