Propuesta de mejora de operación de un sistema de gestión de almacenes en un operador logístico

La presente tesis es un trabajo de investigación y mejora del sistema de gestión de almacenes de una empresa que se dedica al servicio de operador logístico, que incluye el almacenaje de mercadería y la correcta distribución de ésta a los diversos puntos que son requeridos por sus clientes. Para ello se ha contado con el apoyo del personal administrativo y operativo de las diferentes áreas con las que cuenta la empresa, el cual se mostró muy cooperativo al momento de solicitar su ayuda, referente a temas de información y opiniones basadas en su propia experiencia, las que fueron de gran ayuda para el planteamiento de mejoras en este proyecto. Se analizó la información proporcionada por las diversas fuentes de la empresa a fin de poder plantear una mejora en el sistema actual de gestión del almacén. En función de ahorro de recursos, reducción de la rotación de personal, muestreo estratificado y la aplicación de nuevos sistemas de trabajos tales como el JIT o el método de las “5 s”. Con la propuesta se estructura un óptimo sistema de gestión de almacenes, en el que se eliminen las debilidades que presenta el actual, así como inducciones deficientes a personal nuevo o problemas en el servicio de distribución que la empresa ofrece.Tesi

Logarithmic cohomology of the complement of a plane curve

Let D, x be a plane curve germ. We prove that the complex Ω•(log D)x computes the cohomology of the complement of D, x only if D is quasihomogeneous. This is a partial converse to a theorem of F.J. Castro-Jiménez, D. Mond and L. Narváez-Macarro. Cohomology of the complement of a free divisor. Transactions of the A.M.S., 348 (1996), 3037– 3049, which asserts that this complex does compute the cohomology of the complement, whenever D is a locally weighted homogeneous free divisor (and so in particular when D is a quasihomogeneous plane curve germ). We also give an example of a free divisor in D ⊂ C3 which is not locally weighted homogeneous, but for which this (second) assertion continues to hold.Ministerio de Educación y CienciaEngineering and Physical Sciences Research Counci

Efecto del método de emplazamiento en la respuesta funcional de seis especies arbóreas de Bogotá

The increase in urban trees is an progressively common practice around the world given its importance in the provision of different environmental services, although its establishment is carried out under variable space conditions that may impact its development. In this study, the variation of functional traits of six species of the woodland of Bogotá in relation to different methods of sites used in the city was analyzed. The results showed that not all species responded in the same way to the sealing conditions of the soils, in which some benefited from the increase in impervious surfaces, some were affected and others did not show significant changes between different locations. These findings highlight the importance of recognizing the functional component of species in urban areas as a tool for management, seeking to maximize their development and the offer of environmental services.El incremento del arbolado urbano es una práctica cada vez más común en el mundo dada su importancia en la prestación de servicios ambientales, aunque su establecimiento se realiza bajo condiciones de espacio variables que pueden impactar su desarrollo. En este estudio se analizó la variación de rasgos funcionales de seis especies del arbolado de Bogotá en relación con distintos métodos de emplazamientos usados en la ciudad. Los resultados mostraron que no todas las especies reaccionaron de la misma forma frente a las condiciones de sellado del suelo, algunas parecen mejor adaptadas al aumento de las superficies impermeables, mientras otra parece afectarse y las demás no presentaron cambios significativos entre los distintos emplazamientos. Estos hallazgos resaltan la importancia de los rasgos funcionales de las especies, en áreas urbanas, como una herramienta para reconocer su respuesta ante las estrategias de manejo, buscando maximizar su desarrollo y la prestación de servicios ambientales

Women caregivers of dependent relatives and health: Effects of the participation in a stress management workshop

Las tareas de cuidado a dependientes merecen ser objeto de estudio y atención por representar un factor de riesgo para la salud. Por ello analizamos los efectos de ser cuidadora familiar y asistir a un curso de control del estrés, así como la incidencia de dos covariables consideradas relevantes, como son los pensamientos disfuncionales y el tiempo prestando cuidados. Analizamos una muestra de 219 asistentes a talleres psicoeducativos a la que se aplicaron tres instrumentos: cuestionario sociodemográfico, cuestionario de salud general (GHQ28) y pensamientos disfuncionales (CPD). El análisis univariante mostró que ser cuidadora familiar repercute negativamente (p< .001) en todas las escalas del GHQ y que realizar un curso de estrés tiene efectos claramente positivos (p< .05) en la salud general, la somatización y la función social. Asimismo, el análisis de la covarianza mostró que los efectos de ser cuidadora y haber realizado un curso de estrés se mantienen incluso si se consideran los pensamientos disfuncionales y el tiempo cuidando.Dependent care tasks deser ve a special study and attention because of being a health risk factor. That is the reason why we analyzed the effects of working as a family caregiver and of attending a stress management workshop and the impact of two relevant covariables, i.e., dysfunctional thoughts and the time spent providing care. We analyzed a sample of 219 participants attending psychoeducational workshops. Three instruments were applied: A socio-demographic questionnaire, the General Health Questionnaire (GHQ28), and the Dysfunctional Thoughts Questionnaire (CPD). Univariate analysis showed that working as a family caregiver has a negative impact (p< .001) on all GHQ scales and that attending a stress management workshop has a positive effect (p< .05) on general health, somatization and social function. Furthermore, covariance analysis showed that the effects of working as a caregiver and attending a stress management workshop remained significant even when the two covariables (dysfunctional thoughts and time providing care) were considered

Using the Social-Local-Mobile App for Smoking Cessation in the SmokeFreeBrain Project: Protocol for a Randomized Controlled Trial

Background: Smoking is considered the main cause of preventable illness and early deaths worldwide. The treatment usually prescribed to people who wish to quit smoking is a multidisciplinary intervention, combining both psychological advice and pharmacological therapy, since the application of both strategies significantly increases the chance of success in a quit attempt. Objective: We present a study protocol of a 12-month randomized open-label parallel-group trial whose primary objective is to analyze the efficacy and efficiency of usual psychopharmacological therapy plus the Social-Local-Mobile app (intervention group) applied to the smoking cessation process compared with usual psychopharmacological therapy alone (control group). Methods: The target population consists of adult smokers (both male and female) attending the Smoking Cessation Unit at Virgen del Rocío University Hospital, Seville, Spain. Social-Local-Mobile is an innovative intervention based on mobile technologies and their capacity to trigger behavioral changes. The app is a complement to pharmacological therapies to quit smoking by providing personalized motivational messages, physical activity monitoring, lifestyle advice, and distractions (minigames) to help overcome cravings. Usual pharmacological therapy consists of bupropion (Zyntabac 150 mg) or varenicline (Champix 0.5 mg or 1 mg). The main outcomes will be (1) the smoking abstinence rate at 1 year measured by means of exhaled carbon monoxide and urinary cotinine tests, and (2) the result of the cost-effectiveness analysis, which will be expressed in terms of an incremental cost-effectiveness ratio. Secondary outcome measures will be (1) analysis of the safety of pharmacological therapy, (2) analysis of the health-related quality of life of patients, and (3) monitoring of healthy lifestyle and physical exercise habits. Results: Of 548 patients identified using the hospital’s electronic records system, we excluded 308 patients: 188 declined to participate and 120 did not meet the inclusion criteria. A total of 240 patients were enrolled: the control group (n=120) will receive usual psychopharmacological therapy, while the intervention group (n=120) will receive usual psychopharmacological therapy plus the So-Lo-Mo app. The project was approved for funding in June 2015. Enrollment started in October 2016 and was completed in October 2017. Data gathering was completed in November 2018, and data analysis is under way. The first results are expected to be submitted for publication in early 2019. Conclusions: Social networks and mobile technologies influence our daily lives and, therefore, may influence our smoking habits as well. As part of the SmokeFreeBrain H2020 European Commission project, this study aims at elucidating the potential role of these technologies when used as an extra aid to quit smoking

DE UNA MANO MECÁNICA IMPRESA EN 3D A UNA PRÓTESIS MIOELÉCTRICA A BAJO COSTO (PARTE I: INTERFAZ EMG)

En el presente trabajo se desarrolló una interfaz mioeléctrica para controlar un prototipo de prótesis de mano impresa con tecnología 3D. Se logró adquirir y acondicionar señales electromiográficas a través de electrodos de superficie. Dicha interfaz contiene etapas de adquisición, amplificación, filtrado, rectificación y suavizado. Lo que permite obtener amplitudes de señales electromiográficas (EMG) adecuadas para su digitalización dentro de un algoritmo implementado con un microcontrolador Arduino UNO. Para las pruebas de funcionamiento se imprimió en 3D un diseño de mano mecánica (raptor hand, 2017)

Approximation to the Consumption of Healthcare Resources and the Economic Cost of SARS-CoV-2 Patient Management: A Retrospective Study

Spain has become one of the countries most affected by coronavirus disease 2019 (COVID-19), with the highest testing rates, and one of the worst-performing countries in the fight against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. There are no studies related to the consumption of health resources and the economic cost of the SARS-CoV-2 virus. We present a retrospective analysis of 9,811 (Primary Care and Hospital) patients which aimed to estimate public health expenditure by the consumption of health resources due to COVID-19. According to the results, the gender distribution of patients has a similar rate in both groups, with slightly higher rates in women. Similarly, age is the same in both groups, with a median of 62 years in the case of hospitalizations and 61 years in the case of primary care; using a weighted average of these rates and costs, we can estimate that the average cost of care per patient infected with the SARS-CoV-2 virus, regardless of the course is €2373.24. We conclude that a patient with COVID-19 without hospitalization costs €729.79, while the expenses of a hospitalized patient are between €4294.36 and €14440.68, if there is ICU admission

Business consulting – Asema Camisea SAC

Asema Camisea S.A.C. (Asema) nace en marzo del 2016 como un emprendimiento de la Comunidad Nativa de Camisea; siendo en la actualidad la empresa logística más importante de la región del bajo Urubamba, distrito de Megantoni. Es una compañía especializada en logística multimodal, con un directorio conformado por pobladores de la zona conocedores de la problemática y las necesidades de la comunidad. Además de la ubicación estratégica y de generar un impacto positivo, reporta ingresos para la comunidad. La logística integral que brinda la hace una de las más solicitadas en la zona, cuyas diversas actividades, entre ellas el traslado de carga y pasajeros, aunadas con los más altos estándares del mercado, le permite tener contratos con las más importantes compañías petroleras de la región como son Pluspetrol, CNPC, Repsol, la empresa transportadora de gas TGP y su operador COGA, además con las constructoras TECHINT, SICIM y la municipalidad de Megantoni. La pandemia del Covid-19 detuvo la mayoría de sus operaciones. A pesar de que la demanda ha aumentado, no se vislumbra una mejora tangible en la situación actual. Luego de analizar la situación, identificamos que los mayores problemas son la dependencia de los ingresos en la línea de negocio del transporte fluvial y además una dependencia de un solo gran cliente. En este sentido, se propone un plan para la reactivación del transporte fluvial durante la pandemia y la implementación del servicio de hoteles como nueva línea de negocio.Asema Camisea S.A.C. (Asema) was established in March 2016 as a company of the Camisea Native Community; currently being the most important logistics company in the lower Urubamba region, Megantoni district. It’s a company specialized in multimodal logistics, with a directory made up of residents who are knowledgeable about the problems and the needs of the community. In addition to the strategic location and generating a positive impact, this firm also provides income for the community. The integral logistics services that it provides makes it one of the most requested in the area, whose various activities, including the cargo and passengers transfer, combined with the highest market standards, allows it to have contracts with the most important oil companies in the region such as Pluspetrol, CNPC, Repsol, TGP (the gas transport company) and its operator COGA, as well as the construction companies TECHINT, SICIM and the municipality of Megantoni. With the Covid-19 pandemic, demand has increased but most of the operations are on standstill until a favorable situation can be attained. After analyzing the situation, we identified that the greatest problems are the dependence on income in the river transport business line and also a dependence on a single large customer. In view of this, a plan is being proposed for the reactivation of river transport during the pandemic and the implementation of the camp service as a new line of business

Use of a glycogenic precursor during the prepartum period and its effects upon metabolic indicators and reproductive parameters in dairy cows

The aim was to evaluate if 1-2 propanodiol plus calcium propionate (glycogenic precursor) supplementation during the transition period in high yielding dairy cows reduces metabolic and reproductive dysfunctions during early lactation. Cows (n= 202) were divided into two homogeneous groups regarding number of lactations and body condition score. 1) Treated group (GG; n= 112) received 60 g/cow/d for15 d of a glycogenic precursor during the transition period. 2) Control group (GC; n= 90) received no treatment. Postpartum levels of beta hydroxybutyrate (BHB) (GG= 0.9 ± 0.2 mmol/L vs GC =1.3 ± 0.2 mmol/L; P<0.05), and non-esterified fatty acids (NEFA) (GG= 0.6 ± 0.1 mEq/L vs GC = 0.8 ± 0.1 mEq/L; P<0.05) were higher in the GC-group. Similarly, GC-cows had a higher percentage of retained placenta (23 % vs 13 %; P≤0.06) subclinical ketosis (GG= 10 %, GC= 56 %; P<0.05), and mastitis (GG= 8 %, GC= 16 %; P<0.05). Metritis, dystocia, abortions, clinical ketosis, hypocalcemia and ruminal acidosis showed no differences between groups. Administration of a glycogenic precursor during the transition period demonstrated a positive effect upon BHB and NEFA blood levels during early lactation, with parallel decreases of subclinical ketosis and retained placenta; this could be an alternative to enhance the dairy herd reproductive efficiency.The aim was to evaluate if 1-2 propanodiol plus calcium propionate (glycogenic precursor) supplementation during the transition period in high yielding dairy cows reduces metabolic and reproductive dysfunctions during early lactation. Cows (n=202) where divided into two homogeneous groups regarding number of lactations and body condition score. 1) Treated Group (GG; n=112) received 60g/cow/day  15d of a glycogenic precursor during the transition period. 2) Control Group (GC; n = 90) received no treatment. Postpartum levels of BHB (GG= 0.9±0.2 mmol/L vs GC =1.3±0.2 mmol/L; P < 0.05), and NEFA (GG= 0.6 ± 0.1 mEq/L vs GC = 0.8 ± 0.1 mEq/L; P < 0.05) were higher for GC. Likewise, GC-cows had a higher percentage of retained placenta (23% vs. 13%; P ≤ 0.06) subclinical ketosis (GG = 10%, GC = 56%; P < 0.05), and mastitis (GG = 8%, GC = 16%; P < 0.05). Metritis, dystocia, abortions, clinical ketosis, hypocalcemia and ruminal acidosis showed no differences. Administration of a glycogenic precursor during the transition period demonstrated a positive effect upon BHB and NEFA blood levels during early lactation. Also, levels of subclinical ketosis and retained placenta were reduced

A Mobile Health Solution Complementing Psychopharmacology-Supported Smoking Cessation: Randomized Controlled Trial

Background: Smoking cessation is a persistent leading public health challenge. Mobile health (mHealth) solutions are emerging to improve smoking cessation treatments. Previous approaches have proposed supporting cessation with tailored motivational messages. Some managed to provide short-term improvements in smoking cessation. Yet, these approaches were either static in terms of personalization or human-based nonscalable solutions. Additionally, long-term effects were neither presented nor assessed in combination with existing psychopharmacological therapies. Objective: This study aimed to analyze the long-term efficacy of a mobile app supporting psychopharmacological therapy for smoking cessation and complementarily assess the involved innovative technology. Methods: A 12-month, randomized, open-label, parallel-group trial comparing smoking cessation rates was performed at Virgen del Rocío University Hospital in Seville (Spain). Smokers were randomly allocated to a control group (CG) receiving usual care (psychopharmacological treatment, n=120) or an intervention group (IG) receiving psychopharmacological treatment and using a mobile app providing artificial intelligence–generated and tailored smoking cessation support messages (n=120). The secondary objectives were to analyze health-related quality of life and monitor healthy lifestyle and physical exercise habits. Safety was assessed according to the presence of adverse events related to the pharmacological therapy. Per-protocol and intention-to-treat analyses were performed. Incomplete data and multinomial regression analyses were performed to assess the variables influencing participant cessation probability. The technical solution was assessed according to the precision of the tailored motivational smoking cessation messages and user engagement. Cessation and no cessation subgroups were compared using t tests. A voluntary satisfaction questionnaire was administered at the end of the intervention to all participants who completed the trial. Results: In the IG, abstinence was 2.75 times higher (adjusted OR 3.45, P=.01) in the per-protocol analysis and 2.15 times higher (adjusted OR 3.13, P=.002) in the intention-to-treat analysis. Lost data analysis and multinomial logistic models showed different patterns in participants who dropped out. Regarding safety, 14 of 120 (11.7%) IG participants and 13 of 120 (10.8%) CG participants had 19 and 23 adverse events, respectively (P=.84). None of the clinical secondary objective measures showed relevant differences between the groups. The system was able to learn and tailor messages for improved effectiveness in supporting smoking cessation but was unable to reduce the time between a message being sent and opened. In either case, there was no relevant difference between the cessation and no cessation subgroups. However, a significant difference was found in system engagement at 6 months (P=.04) but not in all subsequent months. High system appreciation was reported at the end of the study. Conclusions: The proposed mHealth solution complementing psychopharmacological therapy showed greater efficacy for achieving 1-year tobacco abstinence as compared with psychopharmacological therapy alone. It provides a basis for artificial intelligence–based future approaches. Trial Registration: ClinicalTrials.gov NCT03553173; https://clinicaltrials.gov/ct2/show/NCT03553173 International Registered Report Identifier (IRRID): RR2-10.2196/12464H2020 European Commission research and innovation program grant agreement 68112