3,919 research outputs found
Proton transport and torque generation in rotary biomotors
We analyze the dynamics of rotary biomotors within a simple
nano-electromechanical model, consisting of a stator part and a ring-shaped
rotor having twelve proton-binding sites. This model is closely related to the
membrane-embedded F motor of adenosine triphosphate (ATP) synthase, which
converts the energy of the transmembrane electrochemical gradient of protons
into mechanical motion of the rotor. It is shown that the Coulomb coupling
between the negative charge of the empty rotor site and the positive stator
charge, located near the periplasmic proton-conducting channel (proton source),
plays a dominant role in the torque-generating process. When approaching the
source outlet, the rotor site has a proton energy level higher than the energy
level of the site, located near the cytoplasmic channel (proton drain). In the
first stage of this torque-generating process, the energy of the
electrochemical potential is converted into potential energy of the
proton-binding sites on the rotor. Afterwards, the tangential component of the
Coulomb force produces a mechanical torque. We demonstrate that, at low
temperatures, the loaded motor works in the shuttling regime where the energy
of the electrochemical potential is consumed without producing any
unidirectional rotation. The motor switches to the torque-generating regime at
high temperatures, when the Brownian ratchet mechanism turns on. In the
presence of a significant external torque, created by ATP hydrolysis, the
system operates as a proton pump, which translocates protons against the
transmembrane potential gradient. Here we focus on the F motor, even though
our analysis is applicable to the bacterial flagellar motor.Comment: 24 pages, 5 figure
A study of major coding techniques for digital communication Final report
Coding techniques for digital communication channel
Measuring the Stellar Masses of z~7 Galaxies with Spitzer Ultrafaint Survey Program (SURFS UP)
We present Spitzer/IRAC observations of nine -band dropouts highly
magnified (2<mu<12) by the Bullet Cluster. We combine archival imaging with our
Exploratory program (SURFS UP), which results in a total integration time of
~30 hr per IRAC band. We detect (>3sigma) in both IRAC bands the brightest of
these high-redshift galaxies, with [3.6]=23.80+-0.28 mag, [4.5]=23.78+-0.25
mag, and (H-[3.6])=1.17+-0.32 mag. The remaining eight galaxies are undetected
to [3.6]~26.4 mag and [4.5]~26.0 mag with stellar masses of ~5x10^7 M_sol. The
detected galaxy has an estimated magnification of mu=12+-4, which implies this
galaxy has an ultraviolet luminosity of L_1500~0.3 L*_{z=7} --- the lowest
luminosity individual source detected in IRAC at z>7. By modeling the broadband
photometry, we estimate the galaxy has an intrinsic star-formation rate of
SFR~1.3 M_sol/yr and stellar mass of M~2x10^9 M_sol, which gives a specific
star-formation rate of sSFR~0.7 Gyr^-1. If this galaxy had sustained this
star-formation rate since z~20, it could have formed the observed stellar mass
(to within a factor of ~2), we also discuss alternate star-formation histories
and argue the exponentially-increasing model is unlikely. Finally, based on the
intrinsic star-formation rate, we estimate this galaxy has a likely [C II] flux
of = 10^{-17} erg/s/cm2.Comment: Accepted to ApJL. 6 pages, 3 figures, 2 table
Quantitative Nanofriction Characterization of Corrugated Surfaces by Atomic Force Microscopy
Atomic Force Microscopy (AFM) is a suitable tool to perform tribological
characterization of materials down to the nanometer scale. An important aspect
in nanofriction measurements of corrugated samples is the local tilt of the
surface, which affects the lateral force maps acquired with the AFM. This is
one of the most important problems of state-of-the-art nanotribology, making
difficult a reliable and quantitative characterization of real corrugated
surfaces. A correction of topographic spurious contributions to lateral force
maps is thus needed for corrugated samples. In this paper we present a general
approach to the topographic correction of AFM lateral force maps and we apply
it in the case of multi-asperity adhesive contact. We describe a complete
protocol for the quantitative characterization of the frictional properties of
corrugated systems in the presence of surface adhesion using the AFM.Comment: 33 pages, 9 figures, RevTex 4, submitted to Journal of Applied
Physic
Playing with the future: social irrealism and the politics of aesthetics
In this paper we wish to explore the political possibilities of video games. Numerous scholars now take seriously the place of popular culture in the remaking of our geographies, but video games still lag behind. For us, this tendency reflects a general response to them as imaginary spaces that are separate from everyday life and 'real' politics. It is this disconnect between abstraction and lived experience that we complicate by defining play as an event of what Brian Massumi calls lived abstraction. We wish to short-circuit the barriers that prevent the aesthetic resonating with the political and argue that through their enactment, video games can animate fantastical futures that require the player to make, and reflect upon, profound ethical decisions that can be antagonistic to prevailing political imaginations. We refer to this as social irrealism to demonstrate that reality can be understood through the impossible and the imagined
A characterization of those automata that structurally generate finite groups
Antonenko and Russyev independently have shown that any Mealy automaton with
no cycles with exit--that is, where every cycle in the underlying directed
graph is a sink component--generates a fi- nite (semi)group, regardless of the
choice of the production functions. Antonenko has proved that this constitutes
a characterization in the non-invertible case and asked for the invertible
case, which is proved in this paper
Immune-responses to varicella-zoster in the aged
Skin test reactivity and in vitro lymphocyte stimulation responses to varicella-zoster (VZ) were examined in a large normal population ranging in age from 6 months to 93 years. Waning of cellular immunity, as examined by skin delayed hypersensitivity, began at age 40 years. Skin test responses to phytohemagglutinin, however, remained positive into the eighth decade of life. In vitro lymphocyte stimulation responses to VZ were usually positive (stimulation index ≥2.5) until age 60 years, after which time levels, as observed with nonimmune individuals, were often demonstrated. Antibody levels, as measured by fluorescent antibody to membrane antigen, remained positive into the ninth and tenth decades of life. This was especially so with a history of reactivation (zoster) VZ infections, while skin test and in vitro responses were rarely positive in those individuals. Thus cellular, as contrasted with humoral, immunity decreases with advancing age, which may account for a propensity to reactivation of VZ virus
Methods for Reducing False Alarms in Searches for Compact Binary Coalescences in LIGO Data
The LIGO detectors are sensitive to a variety of noise transients of
non-astrophysical origin. Instrumental glitches and environmental disturbances
increase the false alarm rate in the searches for gravitational waves. Using
times already identified when the interferometers produced data of questionable
quality, or when the channels that monitor the interferometer indicated
non-stationarity, we have developed techniques to safely and effectively veto
false triggers from the compact binary coalescences (CBCs) search pipeline
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