771 research outputs found
The impact of assembly bias on the halo occupation in hydrodynamical simulations
We investigate the variations in galaxy occupancy of the dark matter haloes with the large-scale environment and halo formation time, using two state-of-the-art hydrodynamical cosmological simulations, EAGLE and Illustris. For both simulations, we use three galaxy samples with a fixed number density ranked by stellar mass. For these samples, we find that low-mass haloes in the most dense environments are more likely to host a central galaxy than those in the least dense environments. When splitting the halo population by formation time, these relations are stronger. Hence, at a fixed low halo mass, early-formed haloes are more likely to host a central galaxy than late-formed haloes since they have had more time to assemble. The satellite occupation shows a reverse trend where early-formed haloes host fewer satellites due to having more time to merge with the central galaxy. We also analyse the stellar mass–halo mass relation for central galaxies in terms of the large-scale environment and formation time of the haloes. We find that low-mass haloes in the most dense environment host relatively more massive central galaxies. This trend is also found when splitting the halo population by age, with early-formed haloes hosting more massive galaxies. Our results are in agreement with previous findings from semi-analytical models, providing robust predictions for the occupancy variation signature in the halo occupation distribution of galaxy formation models
Preliminary results on Northern hake from the “Spanish Discard Sampling Programme”
The “Spanish Discard Sampling Programme” was started in 1988, however
it has not had a continuous implementation in time. Results on Northern
hake discard were obtained sampling the Spanish trawl fishery operating in
the Northern hake distribution area. Discarding strategy varies between
fleets, depending mainly on the target species of the fleet. Differences along
the time series were probably due to market changes more than to the
abundance of the species. In the years with a higher sampling quality, 2003
and 2004, the total level of Northern hake discard was estimated to be
around 5% in weight and between 11-15% in number, respectively.
Discards were compounded by ages from 0 to 3, mainly ages 1 and 2
Circulating microparticles from patients with obstructive sleep apnea enhance vascular contraction: mandatory role of the endothelium
Obstructive sleep apnea (OSA) is characterized by repetitive apnea-hypopnea cycles during sleep associated with oxygen desaturation and sleep disruption. We evaluated the role of circulating microparticles (MPs) from patients with OSA in the regulation of vascular function. MPs from whole blood from patients with OSA or control subjects were injected i.v. into mice. Injection of MPs from patients with OSA induced ex vivo vascular hyperreactivity in aortas with functional endothelium but, in contrast, hyporeactivity in vessels without functional endothelium. Vascular hyperreactivity was blunted in the presence of a nitric oxide synthase inhibitor alone or combined with the cyclooxygenase inhibitor indomethacin. MPs from patients with OSA reduced endothelial nitric oxide synthase activity and nitric oxide production, increased aortic cyclooxygenase-1 and cyclooxygenase-2 expression, and increased thromboxane A(2) and prostacyclin production. Blockade of thromboxane A(2) receptor did not affect the serotonin response in arteries from OSA MP-treated mice. A superoxide dismutase mimetic reduced the vascular hyperreactivity induced by MPs from patients with OSA but had no effect on contraction in vessels from control and non-OSA MP-treated mice. These data provide evidence that circulating MPs from patients with OSA induce ex vivo vascular hyperreactivity with the obligatory role of the endothelium and subtle interactions between the nitric oxide and cyclooxygenase pathways and metabolites. These results highlight the participation of MPs in vascular dysfunction associated with OSA
Analysis of genome expression of rhizobium etli in free living and plant-associated symbiotic state
Comunicaciones a congreso
Homogenization of weakly coupled systems of Hamilton--Jacobi equations with fast switching rates
We consider homogenization for weakly coupled systems of Hamilton--Jacobi
equations with fast switching rates. The fast switching rate terms force the
solutions converge to the same limit, which is a solution of the effective
equation. We discover the appearance of the initial layers, which appear
naturally when we consider the systems with different initial data and analyze
them rigorously. In particular, we obtain matched asymptotic solutions of the
systems and rate of convergence. We also investigate properties of the
effective Hamiltonian of weakly coupled systems and show some examples which do
not appear in the context of single equations.Comment: final version, to appear in Arch. Ration. Mech. Ana
Evaluation of the Charm maximum residue limit beta-lactam and tetracycline test for the detection of antibiotics in ewe and goat milk
The Charm maximum residue limit P-lactam and tetracycline test (Charm MRL BLTET; Charm Sciences Inc., Lawrence, MA) is an immunoreceptor assay utilizing Rapid. One-Step Assay lateral flow technology that detects P-lactam or tetracycline drugs in raw commingled cow milk at or below European Union maximum residue levels (EU-MRL). The Charm MRL BLTET test procedure was recently modified (dilution in buffer and longer incubation) by the manufacturers to be used with raw ewe and goat milk. To assess the Charm MRL BLTET test for the detection of beta-lactams and tetracyclines in milk of small ruminants, an evaluation study was performed at Instituto de Ciencia y Tecnologia Animal of Universitat Politecnica de Valencia (Spain). The test specificity and detection capability (CC beta) were studied following Commission Decision 2002/657/EC. Specificity results obtained in this study were optimal for individual milk free of antimicrobials from ewes (99.2% for beta-lactams and 100% for tetracyclines) and goats (97.9% for beta-lactams and 100% for tetracyclines) along the entire lactation period regardless of whether the results were visually or instrumentally interpreted. Moreover, no positive results were obtained when a relatively high concentration of different substances belonging to antimicrobial families other than beta-lactams and tetracyclines were present in ewe and goat milk. For both types of milk, the CC beta calculated was lower or equal to EU-MRL for amoxicillin (4 mu g/kg), ampicillin (4 mu g/kg), benzylpenicillin (30 mu g/kg). The CC beta for tetracyclines was also lower than EU-MRL for chlortetracycline (ewe milk: <= 50 mu g/kg; goat milk: 75 mu g/kg), oxytetracycline (<= 50 mu g/kg), and tetracycline (<= 50 mu g/kg). Regarding the 4-epimers of these tetracyclines only 4-epioxytetracycline was detected by the Charm MRL BLTET test below EU-MRL (ewe milk: 75 mu g/kg; goat milk: <= 50 mu g/kg). Acidiol had no effect on the performance of the test. The Charm MRL BLTET test could be used routinely with adapted test procedure for the fast screening of ewe and goat milk.This work forms part of the Project AGL2009-11524 financed by the Ministerio de Ciencia e Innovacion (Madrid, Spain). The authors are grateful to Fatro S.p.A. (Bologna, Italy) and ACS Dobfar S.p.A. (Milan, Italy) for kindly providing cefacetrile and desacetylcefapirin, respectively. Moreover, the authors thank Charm Sciences, Inc. (Lawrence, MA) and especially Wilbert Kokke from Charm Sciences Inc. and Raul Gomez from Grupo Taper, S.A. (Madrid, Spain) for their support.Beltrán Martínez, MC.; Romero Rueda, T.; Althaus, RL.; Molina Pons, MP. (2013). Evaluation of the Charm maximum residue limit beta-lactam and tetracycline test for the detection of antibiotics in ewe and goat milk. Journal of Dairy Science. 96(5):2737-2745. https://doi.org/10.3168/jds.2012-6044S2737274596
Preserved insulin vasorelaxation and up-regulation of the Akt/eNOS pathway in coronary arteries from insulin resistant obese Zucker rats
Obesity is associated with insulin resistance in the peripheral vasculature and is an important risk factor for coronary artery disease. The current study assessed whether the vascular effects and the signaling pathways of insulin are impaired in coronary arteries from a rat model of genetic obesity. Intramyocardial arteries from obese Zucker rats (OZR) and lean Zucker rats (LZR) were mounted in microvascular myographs to assess insulin vasoactive effects and the proteins of the insulin pathway were determined by Western blotting. The endothelium-dependent and nitric oxide (NO)-mediated vasorelaxant effect of insulin was similar in arteries from LZR and OZR and blunted by inhibition of phosphatidylinositol 3-kinase (PI3K) and endothelial NO synthase (eNOS), but unaltered by either mitogen activated protein kinase (MAPK) or endothelin (ET) receptor blockade. Basal levels of phospho-eNOS Ser1177 and phospho-Akt Ser473 were up-regulated in OZR, and insulin increased phosphorylation of eNOS and Akt in both LZR and OZR. Moreover, insulin enhanced Akt expression in LZR. Basal and insulin-stimulated levels of phospho-MAPK p42/p44 were lower in OZR and palmitic acid reduced these levels in LZR. Coronary arteries are protected from vascular IR. The results underscore the fact that preservation of insulin-mediated vasorelaxation along with an up-regulation of the Akt/eNOS pathway and an impairment of the MAPK cascade account for this protection
Comparison of fiber effect on glycemic index and glycemic load in differents types of bread
Indexación: Scopus; Redalyc.Existen diversos alimentos que contienen como nutriente
principal hidratos de carbono, destacando entre ellos el pan
por su masivo consumo a nivel mundial. Numerosos estudios
se han llevado a cabo con el fin de reducir su índice glicémico,
sin embargo, aún existe controversia sobre la acción de
la fibra dietética en la disminución del IG en este alimento.
Este estudio determinó el efecto de la fibra dietética sobre el
índice glicémico y carga glicémica en dos tipos de panes comerciales
en 23 individuos sanos quienes consumieron aleatoriamente
3 diferentes productos, de 50 g de carbohidratos
cada uno, durante 6 días: pan blanco (PH), pan integral (PF),
y solución glucosada como producto de referencia (SG). Se
midió glicemia en ayunas y post-prandial a los tiempos 15,
30, 45, 60, 90 y 120 min. La insulina fue medida en el minuto
0 y 120 min. El área bajo la curva de glicemia resultó
más baja para ambos tipos de pan PH 13589 ±1557, PF
12005 ±1254 que para el producto de referencia SG 14089
±1245. Los valores del índice glicémico PH 68,55 ±1,2 y PF
62,10 ±1,3 y carga glicémica PH 16,45 ±1,4 resultaron más
bajos para el pan con mayor aporte de fibra 9,93 ± 1,1, sin
diferencias en la concentración de insulina, sugiriendo que
la cantidad de carbohidratos y tipo de fibra contenidos en el
pan integral, pueden considerarse factores intrínsecos en su
composición nutricional, capaces de afectar la respuesta glicémica
post- ingesta de estos productos en individuos sanos.There are several foods that contain carbohydrates as the
main nutrient, being one of the most important the bread for
its massive worldwide consumption. Numerous studies have
been done in order to reduce its glycemic index, however
there is still controversy about the action of dietary fiber in the
decrease of GI in this product. In this study, it was determined
the effect of dietetic fiber on glycemic index and glycemic load
in two types of commercial breads in 23 healthy individuals
who randomly consumed 3 different products during 6 days
of 50g of carbohydrates each: white bread (PH), whole wheat
bread (PE) and glucose solution as reference product (SG).
Fasting and postprandial glycemia was measured at times
15, 30, 45, 60, 90 and 120 minutes. Insuline was measured
at 0 min and 120 min. The area under de glycemia curve
was lower for both bread types PH 13589 ±1557, PF 12005
±1254 than for the reference product SG 14089 ±1245. The
values of the glycemic index PH 68,55 ±1,2 and PF 62,01
±1,3 and glycemic load PH 16.45 ±1,4 were lower for bread
with more amount fiber 9,93 ± 1,1, with no difference in insulin
concentration, suggesting that the amount of carbohydrates
and fiber type contained in whole wheat bread can
be considered intrinsic factors in bread composition, affecting
the post-intake glycemic response of this type of products in
healthy individuals.http://www.redalyc.org/articulo.oa?id=5594990800
Effect of oat β-glucan on glycemic index and glycemic load of a nutritional supplement sweetened with sucralose in healthy adults: A randomized clinical trial
Indexación: Scopus; RedalycLas propiedades hipoglicemiantes del β-glucano de avena
son de interés para la industria alimentaria y el área clínica,
por sus potenciales beneficios sobre la salud al disminuir la
respuesta glicémica, el nivel sérico de lipoproteínas de baja
densidad y el índice glicémico de los alimentos. Existen suplementos
nutricionales específicos para diabéticos edulcorados
con sucralosa cuyo índice glicémico y carga glicémica
aún no han sido establecidos. El efecto del β-glucano de
avena sobre el índice glicémico y carga glicémica de un suplemento
nutricional edulcorado con sucralosa, fue determinado
en 13 adultos sanos (6 hombres y 7 mujeres), quienes
consumieron aleatoriamente 4 alimentos en días distintos, de
50 g de carbohidratos cada uno: suplemento nutricional para
diabéticos (FN), suplemento nutricional con β-glucano (FN-
β), y como productos de referencia: solución glucosada (SG)
y pan blanco (PB). Se midió glicemia en ayunas y post- prandial
a los tiempos 15, 30, 45, 60, 90 y 120 min. El área bajo
la curva de glicemia resultó más baja para ambas fórmulas
(FN) 12697±993, (FN-β) 11584 ±1171, que para los productos
de referencia:(SG) 13900±1245, y (PB) 13267 ± 1557.
Los valores de índice glicémico (FN) 67,02 ± 5,69, así como
la carga glicémica resultaron intermedios y más bajos para el
suplemento con β-glucano incorporado (FN –β) 59,8 ± 6,2;
sin diferencias en la concentración de insulina, sugiriendo
que la adición del β-glucano derivado de la avena reduce la
velocidad de absorción intestinal de la glucosa, efecto que
podría estudiarse en diabéticos.The hypoglycemic properties of oat β-glucan is of interest
for the food industry and clinical area, for potencial health
benefits by reducing glycemic response, serum low-density
lipoprotein cholesterol, and glycemic index of meals. There
are specific nutritional supplements for diabetics sweetened
with sucralose whose glycemic index and glycemic load has
not been established. Effect of oat β-glucan on glycemic
index and glycemic load of a nutritional supplement sweetened
with sucralose in healthy adults was determined in 13
healthy subjects (6 men and 7 women) old that consumed
randomly 4 meals of 50 g of carbohydrates each in different
days: a nutritional supplement for diabetics (FN), the nutritional
supplement with β-glucan incorporated (FN-β) and two
reference food, glucose solution (SG) and white bread (PB).
Fasting and postprandial glycemia was measured at times
15, 30, 45, 60, 90 and 120 min. The area under the glycemia
curve was lower for both formulas (FN) 12697±993, (FN-β)
11584 ±1171 than for reference products (SG) 13900±1245,
y (PB) 13267 ± 1557. The values of glycemic index (GI) (FN)
67, 02 ± 5,69 and glycemic load were intermediate and more
lower for the supplement with β-glucan incorporated (FN –β)
59, 8 ± 6,2, with no difference of insulin concentration . Suggesting
that the addition of oat-derived β-glucan reduces the
rate of intestinal absorption of glucose. This effect should be
studied in diabetic.http://www.redalyc.org/articulo.oa?id=5594990800
Phase correction for ALMA. Investigating water vapour radiometer scaling: The long-baseline science verification data case study
Instrumentatio
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