584 research outputs found
Chiral molecule adsorption on helical polymers
We present a lattice model for helicity induction on an optically inactive
polymer due to the adsorption of exogenous chiral amine molecules. The system
is mapped onto a one-dimensional Ising model characterized by an on-site
polymer helicity variable and an amine occupancy one. The equilibrium
properties are analyzed at the limit of strong coupling between helicity
induction and amine adsorption and that of non-interacting adsorbant molecules.
We discuss our results in view of recent experimental results
Constant Curvature Coefficients and Exact Solutions in Fractional Gravity and Geometric Mechanics
We study fractional configurations in gravity theories and Lagrange
mechanics. The approach is based on Caputo fractional derivative which gives
zero for actions on constants. We elaborate fractional geometric models of
physical interactions and we formulate a method of nonholonomic deformations to
other types of fractional derivatives. The main result of this paper consists
in a proof that for corresponding classes of nonholonomic distributions a large
class of physical theories are modelled as nonholonomic manifolds with constant
matrix curvature. This allows us to encode the fractional dynamics of
interactions and constraints into the geometry of curve flows and solitonic
hierarchies.Comment: latex2e, 11pt, 27 pages, the variant accepted to CEJP; added and
up-dated reference
Identity of the imaginary-time and real-time thermal propagators for scalar bound states in a one-generation Nambu-Jona-Lasinio model
By rigorous reanalysis of the results, we have proven that the propagators at
finite temperature for scalar bound states in one-generation fermion condensate
scheme of electroweak symmetry breaking are in fact identical in the
imaginary-time and the real-time formalism. This dismisses the doubt about
possible discrepancy between the two formalisms in this problem. Identity of
the derived thermal transformation matrices of the real-time matrix propagators
for scalar bound states without and with chemical potential and the ones for
corresponding elementary scalar particles shows similarity of thermodynamic
property between the two types of particles. Only one former inference is
modified, i.e. when the two flavors of fermions have unequal nonzero masses,
the amplitude of the composite Higgs particle will decay instead grow in time.Comment: 5 pages, revtex4, no figure
A Generalized Fluctuation-Dissipation Theorem for Nonlinear Response Functions
A nonlinear generalization of the Fluctuation-Dissipation Theorem (FDT) for
the n-point Green functions and the amputated 1PI vertex functions at finite
temperature is derived in the framework of the Closed Time Path formalism. We
verify that this generalized FDT coincides with known results for n=2 and 3.
New explicit relations among the 4-point nonlinear response and correlation
(fluctuation) functions are presented.Comment: 34 pages, Revte
Dispersive properties of quasi-phase-matched optical parametric amplifiers
The dispersive properties of non-degenerate optical parametric amplification
in quasi-phase-matched (QPM) nonlinear quadratic crystals with an arbitrary
grating profile are theoretically investigated in the no-pump-depletion limit.
The spectral group delay curve of the amplifier is shown to be univocally
determined by its spectral power gain curve through a Hilbert transform. Such a
constraint has important implications on the propagation of spectrally-narrow
optical pulses through the amplifier. In particular, it is shown that anomalous
transit times, corresponding to superluminal or even negative group velocities,
are possible near local minima of the spectral gain curve. A possible
experimental observation of such effects using a QPM Lithium-Niobate crystal is
suggested.Comment: submitted for publicatio
Two mechanisms for the elimination of pinch singularities in out of equilibrium thermal field theories
We analyze ill-defined pinch singularities characteristic of out of
equilibrium thermal field theories. We identify two mechanisms that eliminate
pinching even at the single self-energy insertion approximation to the
propagator: the first is based on the vanishing of phase space at the singular
point (threshold effect). It is effective in QED with a massive electron and a
massless photon. In massless QCD, this mechanism fails, but the pinches cancel
owing to the second mechanism, i.e., owing to the spinor/tensor structure of
the single self-energy insertion contribution to the propagator. The
constraints imposed on distribution functions are very reasonable.Comment: 24 pages, Latex, no figures, revised version, many minor changes and
correction
Amino-terminal Polypeptides of Vimentin Are Responsible for the Changes in Nuclear Architecture Associated with Human Immunodeficiency Virus Type 1 Protease Activity in Tissue Culture Cells
The cytotoxicity and synergistic potential of aspirin and aspirin analogues towards oesophageal and colorectal cancer
Background: Oesophageal cancer (OC) is a deadly cancer because of its aggressive nature with survival rates that have barely improved in decades. Epidemiologic studies have shown that low-dose daily intake of aspirin can decrease the incidence of OC. Methods: The toxicity of aspirin and aspirin derivatives to OC and a colorectal cancer (CRC) cell line were investigated in the presence and absence of platins. Results: The data in this study show the effects of a number of aspirin analogues and aspirin on OC cell lines that originally presented as squamous cell carcinoma (SSC) and adenocarcinoma (ADC). The aspirin analogues fumaryldiaspirin (PN517) and the benzoylsalicylates (PN524, PN528 and PN529), were observed to be more toxic against the OC cell lines than aspirin. Both quantitative and qualitative apoptosis experiments reveal that these compounds largely induce apoptosis, although some necrosis was evident with PN528 and PN529. Failure to recover following the treatment with these analogues emphasized that these drugs are largely cytotoxic in nature. The OE21 (SSC) and OE33 (ADC) cell lines were more sensitive to the aspirin analogues compared to the Flo-1 cell line (ADC). A non-cancerous oesophageal primary cells NOK2101, was used to determine the specificity of the aspirin analogues and cytotoxicity assays revealed that analogues PN528 and PN529 were selectively toxic to cancer cell lines, whereas PN508, PN517 and PN524 also induced cell death in NOK2101. In combination index testing synergistic interactions of the most promising compounds, including aspirin, with cisplatin, oxaliplatin and carboplatin against the OE33 cell line and the SW480 CRC cell line were investigated. Compounds PN517 and PN524, and to a lesser extent PN528, synergised with cisplatin against OE33 cells. Cisplatin and oxaliplatin synergised with aspirin and PN517 when tested against the SW480 cell line. Conclusion: These findings indicate the potential and limitations of aspirin and aspirin analogues as chemotherapeutic agents against OC and CRC when combined with platins
Global Search for New Physics with 2.0/fb at CDF
Data collected in Run II of the Fermilab Tevatron are searched for
indications of new electroweak-scale physics. Rather than focusing on
particular new physics scenarios, CDF data are analyzed for discrepancies with
the standard model prediction. A model-independent approach (Vista) considers
gross features of the data, and is sensitive to new large cross-section
physics. Further sensitivity to new physics is provided by two additional
algorithms: a Bump Hunter searches invariant mass distributions for "bumps"
that could indicate resonant production of new particles; and the Sleuth
procedure scans for data excesses at large summed transverse momentum. This
combined global search for new physics in 2.0/fb of ppbar collisions at
sqrt(s)=1.96 TeV reveals no indication of physics beyond the standard model.Comment: 8 pages, 7 figures. Final version which appeared in Physical Review D
Rapid Communication
Observation of Orbitally Excited B_s Mesons
We report the first observation of two narrow resonances consistent with
states of orbitally excited (L=1) B_s mesons using 1 fb^{-1} of ppbar
collisions at sqrt{s} = 1.96 TeV collected with the CDF II detector at the
Fermilab Tevatron. We use two-body decays into K^- and B^+ mesons reconstructed
as B^+ \to J/\psi K^+, J/\psi \to \mu^+ \mu^- or B^+ \to \bar{D}^0 \pi^+,
\bar{D}^0 \to K^+ \pi^-. We deduce the masses of the two states to be m(B_{s1})
= 5829.4 +- 0.7 MeV/c^2 and m(B_{s2}^*) = 5839.7 +- 0.7 MeV/c^2.Comment: Version accepted and published by Phys. Rev. Let
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