Impact of Conditions of Water Supply on the Germination of Tomato and Pepper Seeds

The influence of the cold radiofrequency air plasma treatment on the imbibition and germination of tomato (Solanum lycopersicum) and pepper (Capsicum annuum) seeds, exerted to conditions appearing in natural seedbeds, was investigated. Various conditions of water supply (from nonrestricted water supply to water drought stress) to the germinating seeds were studied. Plasma treatment markedly increased the water imbibition in the case of tomato seeds under limited water availability conditions. Cold radiofrequency plasma treatment had no noticeable impact on the germination of tomato and pepper seeds under the conditions of nonrestricted water supply. In the case of drought stress for both studied cultivars, the cold plasma treatment essentially influenced the germination rate and the kinetics of germination (the median of the Richards’ curve was changed essentially under conditions of water drought)

Neuroprotective Effect of Hyperbaric Oxygen Therapy on Anterior Ischemic Optic Neuropathy

The study investigated the therapeutic effect of hyperbaric oxygen (HBO) on anterior ischemic optic neuropathy in a rodent model (rAION). rAION was laser-induced in one eye of 63 mice. The fellow (uninjured) eye served as an internal control. Thirty-three mice underwent two 90-min sessions of 100% oxygen (2 atm) treatment immediately following injury and one session daily thereafter for up to 14 days. The remaining mice were untreated. Retinas were harvested at different time points, and mRNA levels of various genes were analyzed by real-time polymerase chain reaction and histologic study. Untreated mice: day 1 post-rAION – SOD-1 (oxidative-stress-related) decreased to 82% of control (uninjured eye) levels (P < 0.05), Caspase-3 (proapoptotic) decreased to 89%, Bcl-xL mildly increased (117%; all NS); day 3 – HO-1 and endothelial nitric oxide synthase (eNOS; ischaemia-related) decreased to 74%, and Bcl-2-associated X protein, Caspase-3, and B-cell lymphoma 2 (Bcl-2; apoptotic) increased by 170, 120, and 111%, respectively (all NS); day 21 – HO-1 increased to 222% (NS) and eNOS decreased to 48% (P < 0.05). Treated mice: day 1 – SOD-1 and Caspase-3 remained unchanged, Bcl-2 and Bcl-xL mildly increased (112 and 126% respectively); day 3 – HO-1 and eNOS increased, apoptosis-related gene decreased; day 21 – SOD-1 decreased whereas eNOS increased (P < 0.05), and HO-1 increased to a lesser degree than without treatment. None of the oxygen-treated animals had retinal ganglion cell loss or a decrease in Thy-1 expression. In conclusion, HBO treatment after rAION induction influences the expression of apoptosis-related genes as well as oxidative-stress-induced and ischaemia-related genes and may exert a neuroprotective effect

Estimation of Exposure Distribution Adjusting for Association Between Exposure Level and Detection Limit

In environmental exposure studies, it is common to observe a portion of exposure measurements to fall below experimentally determined detection limits (DLs). The reverse Kaplan–Meier estimator, which mimics the well‐known Kaplan–Meier estimator for right‐censored survival data with the scale reversed, has been recommended for estimating the exposure distribution for the data subject to DLs because it does not require any distributional assumption. However, the reverse Kaplan–Meier estimator requires the independence assumption between the exposure level and DL and can lead to biased results when this assumption is violated. We propose a kernel‐smoothed nonparametric estimator for the exposure distribution without imposing any independence assumption between the exposure level and DL. We show that the proposed estimator is consistent and asymptotically normal. Simulation studies demonstrate that the proposed estimator performs well in practical situations. A colon cancer study is provided for illustration

The impact of the mixing properties within the Antarctic stratospheric vortex on ozone loss in spring

Calculations of equivalent length from an artificial advected tracer provide new insight into the isentropic transport processes occurring within the Antarctic stratospheric vortex. These calculations show two distinct regions of approximately equal area: a strongly mixed vortex core and a broad ring of weakly mixed air extending out to the vortex boundary. This broad ring of vortex air remains isolated from the core between late winter and midspring. Satellite measurements of stratospheric H2O confirm that the isolation lasts until at least mid-October. A three-dimensional chemical transport model simulation of the Antarctic ozone hole quantifies the ozone loss within this ring and demonstrates its isolation. In contrast to the vortex core, ozone loss in the weakly mixed broad ring is not complete. The reasons are twofold. First, warmer temperatures in the broad ring prevent continuous polar stratospheric cloud (PSC) formation and the associated chemical processing (i.e., the conversion of unreactive chlorine into reactive forms). Second, the isolation prevents ozone-rich air from the broad ring mixing with chemically processed air from the vortex core. If the stratosphere continues to cool, this will lead to increased PSC formation and more complete chemical processing in the broad ring. Despite the expected decline in halocarbons, sensitivity studies suggest that this mechanism will lead to enhanced ozone loss in the weakly mixed region, delaying the future recovery of the ozone hole

Spectroscopic Analysis of H I Absorption Line Systems in 40 HIRES Quasars

We list and analyze H I absorption lines at redshifts 2 < z < 4 with column density (12 < log(N_HI) < 19) in 40 high-resolutional (FWHM = 8.0 km/s) quasar spectra obtained with the Keck+HIRES. We de-blend and fit all H I lines within 1,000 km/s of 86 strong H I lines whose column densities are log(N_HI/[cm^-2]) > 15. Unlike most prior studies, we use not only Lya but also all visible higher Lyman series lines to improve the fitting accuracy. This reveals components near to higher column density systems that can not be seen in Lya. We list the Voigt profile fits to the 1339 H I components that we found. We examined physical properties of H I lines after separating them into several sub-samples according to their velocity separation from the quasars, their redshift, column density and the S/N ratio of the spectrum. We found two interesting trends for lines with 12 < log(N_HI) < 15 which are within 200-1000 km/s of systems with log(N_HI) > 15. First, their column density distribution becomes steeper, meaning relatively fewer high column density lines, at z < 2.9. Second, their column density distribution also becomes steeper and their line width becomes broader by about 2-3 km/s when they are within 5,000 km/s of their quasar.Comment: 32 pages, 14 figures, accepted for publication in the Astronomical Journal. A complete version with all tables and figures is available at http://www.astro.psu.edu/users/misawa/pub/Paper/40hires.ps.g

The Effect of Environment on Shear in Strong Gravitational Lenses

Using new photometric and spectroscopic data in the fields of nine strong gravitational lenses that lie in galaxy groups, we analyze the effects of both the local group environment and line-of-sight galaxies on the lens potential. We use Monte Carlo simulations to derive the shear directly from measurements of the complex lens environment, providing the first detailed independent check of the shear obtained from lens modeling. We account for possible tidal stripping of the group galaxies by varying the fraction of total mass apportioned between the group dark matter halo and individual group galaxies. The environment produces an average shear of gamma = 0.08 (ranging from 0.02 to 0.17), significant enough to affect quantities derived from lens observables. However, the direction and magnitude of the shears do not match those obtained from lens modeling in three of the six 4-image systems in our sample (B1422, RXJ1131, and WFI2033). The source of this disagreement is not clear, implying that the assumptions inherent in both the environment and lens model approaches must be reconsidered. If only the local group environment of the lens is included, the average shear is gamma = 0.05 (ranging from 0.01 to 0.14), indicating that line-of-sight contributions to the lens potential are not negligible. We isolate the effects of various theoretical and observational uncertainties on our results. Of those uncertainties, the scatter in the Faber-Jackson relation and error in the group centroid position dominate. Future surveys of lens environments should prioritize spectroscopic sampling of both the local lens environment and objects along the line of sight, particularly those bright (I < 21.5) galaxies projected within 5' of the lens.Comment: Accepted for publication in The Astrophysical Journal; 28 pages, 9 figures, 5 table

Triphenyltin Chloride Delays Leydig Cell Maturation During Puberty in Rats

Triphenyltin chloride (TPT) is present in a wide range of human foods. TPT could disrupt testis function as a potential endocrine disruptor of Leydig cells. However, the effect of TPT on pubertal Leydig cell development is still unclear. The objective of the current study was to explore whether exposure to TPT affected Leydig cell developmental process and to clarify the underlying mechanisms. Male Sprague-Dawley rats at 35 days of age were randomly divided into four groups and received normal corn oil (control), 0.5, 1, or 2 mg/kg/day TPT for 18 days. Immature Leydig cells isolated from 35-day-old rat testes were treated with TPT (10 and 100 nM) for 24 h in vitro. In vivo exposure to ≥0.5 mg/kg TPT lowered serum testosterone levels and lowered Star mRNA. TPT at 2 mg/kg also lowered Lhcgr, Cyp11a1, Hsd3b1, Hsd17b3 as well as pAKT1/AKT1, pAKT2/AKT2, and pERK1/2/ERK1/2 ratios. In vitro exposure to TPT (100 nM) increased ROS production and induced cell apoptosis rate in rat immature Leydig cells. In conclusion, TPT exposure disrupts Leydig cell development possibly via interfering with the phosphorylation of AKT1, AKT2, and ERK1/2 kinases

Diseño de 1600 ML de adoquinado, ubicado en los barrios: anexo a la villa Victoria de julio, Antonio Mendoza y Rubén Ulloa; en el casco urbano de Tipitapa, municipio de Managua

El desarrollo de nuestro país se basa en elementos fundamentales, como: agricultura industria, ganadería, comercio, turismo, etc. Pero el factor determinante entre estos es el sistema nacional de transporte es decir: transporte terrestre, transporte aéreo, transporte marítimo, etc. el cual es el enlace principal para el desarrollo de la sociedad. En Nicaragua el transporte terrestre es el más utilizado por la población, y debido al aumento de la movilización de vehículos con motores más potentes por las vías, obliga a la modernización de la infraestructura vial, permitiendo un tránsito más seguro y eficiente. El incremento de la red vial está vinculado directamente con la economía de nuestro país, pues su papel es primordial en las actividades que se realizan a diario en los diferentes sectores que aportan a la economía nacional. Actualmente la construcción de nuevas vías de comunicación, rehabilitación de carreteras y mejoras de los caminos ya existentes debe ser una necesidad para los gobiernos, ya que constituyen un componente fundamental para el bienestar y desarrollo de la sociedad, además su diseño debe adoptar las condiciones necesarias para obtener una obra de calidad; cumpliéndose en el todos los principios y normas correspondientes al diseño de carreteras. El presente trabajo denominado ‘‘Diseño de 1600 ML de calle, ubicados en los barrios: Anexo la Villa Rubén Ulloa, Villa Victoria de Julio y Antonio Mendoza localizados en el casco urbano de Tipitapa, municipio de Managua’’. Muestra en su contenido los estudios, métodos y normas aplicables para elaborar: el diseño geométrico de la vía, diseño hidráulico y de la estructura de pavimento, tomando en cuenta las especificaciones correspondientes al diseño de carreteras en Nicaragua

Fibroblast Growth Factor 1 Promotes Rat Stem Leydig Cell Development

Fibroblast growth factor 1 (FGF1) is reported to be expressed in the testis. How FGF1 affects stem Leydig cell development remains unclear. Here, we report the effects of FGF1 on rat stem Leydig cell development in an ethane dimethane sulfonate (EDS)-treated model. FGF1 (100 ng/testis) significantly increased serum testosterone level, increased PCNA-positive Leydig cell percentage and Leydig cell number, but down-regulated the expression of Lhcgr, Star, Cyp11a1, Hsd3b1, Cyp17a1, and Hsd11b1 in Leydig cells per se, after its daily intratesticular injection from post-EDS day 14 for 14 days. Primary culture of the seminiferous tubules showed that FGF1 stimulated EdU incorporation to stem Leydig cells but blocked the differentiation into the Leydig cell lineage, possibly via FGFR1-mediated mechanism. In conclusion, FGF1 promotes stem Leydig cell proliferation but blocks its differentiation