534 research outputs found
MarsLux: HI-Resolution Illumination Maps Generator for Mars
Illumination simulation codes for the Moon's surface have been thoroughly developed during the last years. Despite works done for the Moon, no studies have investigated the relation between sunlight illumination and the Martian surface applying those codes done for the Moon to Mars. The objective of this work is to describe the development of a surface illumination simulation code, called MarsLux, which allows users to make a detailed investigation of the illumination conditions on Mars, based on its topography and the relative position of the Sun. Our code can derive accurate illumination maps, form topographic data, showing areas that are fully illuminated, areas in total shadow, and areas with partial shade, in short computational times. Although the code does not take into account any atmospheric effect, the results proved to be of high accuracy. The maps generated are useful for geomorphological studies, to study gullies, thermal weathering, or mass wasting processes as well as for producing energy budget maps for future exploration missions.Fil: Spagnuolo, Mauro Gabriel. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Oficina de CoordinaciĂłn Administrativa Ciudad Universitaria. Instituto de Estudios Andinos "Don Pablo Groeber". Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Estudios Andinos "Don Pablo Groeber"; ArgentinaFil: Carballo, Federico Daniel. Servicio Geologico Minero Argentino; ArgentinaFil: Marco Figuera, R.. Jacobs University Bremen; AlemaniaFil: Rossi, A. P.. Jacobs University Bremen; Alemani
How can Plan Ceibal Land into the Age of Big Data?
In 2007, Plan Ceibal became the first nationwide ubiquitous educational computer program in the world based on the 1:1 model. It is one of the most important programs implemented by Uruguayâs Government to minimize digital divide and is based upon three pillars: equity, learning and technology. As of 2007, Plan Ceibal has covered all public schools, providing every student and teacher in kindergarten, primary and middle school with a laptop or tablet and internet access in the school. To date, Plan Ceibal has close to 700,000 beneficiaries, each with their own device. Since 2011, the Plan has focused on providing the learning community with a wide range of digital content to enhance the teaching and learning process, most notably Learning Management Systems, Mathematics Adaptive Platform, remote English teaching and an online library. Today, Plan Ceibal operates and integrates a large scale of databases fed by a number of management and educational activities. This abundance of data presents a great challenge and a large opportunity to exploit and transform mass data into rich information. The main goal of this article is to describe the most relevant data sources and present an ongoing data analysis research grounded by a case study. In addition, this paper suggests next steps required to implement a learning analytics strategy within Plan Ceibal. If well exploited, this evidence based data can be used to support and improve the current technology and learning educational policies.IB
A High-Density Linkage Map of the Forage Grass Eragrostis curvula and Localization of the Diplospory Locus
Eragrostis curvula (Schrad.) Nees (weeping lovegrass) is an apomictic species native to Southern Africa that is used as forage grass in semiarid regions of Argentina. Apomixis is a mechanism for clonal propagation through seeds that involves the avoidance of meiosis to generate an unreduced embryo sac (apomeiosis), parthenogenesis, and viable endosperm formation in a fertilization-dependent or -independent manner. Here, we constructed the first saturated linkage map of tetraploid E. curvula using both traditional (AFLP and SSR) and high-throughput molecular markers (GBS-SNP) and identified the locus controlling diplospory. We also identified putative regulatory regions affecting the expressivity of this trait and syntenic relationships with genomes of other grass species. We obtained a tetraploid mapping population from a cross between a full sexual genotype (OTA-S) with a facultative apomictic individual of cv. Don Walter. Phenotypic characterization of F1 hybrids by cytoembryological analysis yielded a 1:1 ratio of apomictic vs. sexual plants (34:27, X2 = 0.37), which agrees with the model of inheritance of a single dominant genetic factor. The final number of markers was 1,114 for OTA-S and 2,019 for Don Walter. These markers were distributed into 40 linkage groups per parental genotype, which is consistent with the number of E. curvula chromosomes (containing 2 to 123 markers per linkage group). The total length of the OTA-S map was 1,335 cM, with an average marker density of 1.22 cM per marker. The Don Walter map was 1,976.2 cM, with an average marker density of 0.98 cM/marker. The locus responsible for diplospory was mapped on Don Walter linkage group 3, with other 65 markers. QTL analyses of the expressivity of diplospory in the F1 hybrids revealed the presence of two main QTLs, located 3.27 and 15 cM from the diplospory locus. Both QTLs explained 28.6% of phenotypic variation. Syntenic analysis allowed us to establish the groups of homologs/homeologs for each linkage map. The genetic linkage map reported in this study, the first such map for E. curvula, is the most saturated map for the genus Eragrostis and one of the most saturated maps for a polyploid forage grass species.Fil: Zappacosta, Diego Carlos. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - BahĂa Blanca. Centro de Recursos Naturales Renovables de la Zona SemiĂĄrida. Universidad Nacional del Sur. Centro de Recursos Naturales Renovables de la Zona SemiĂĄrida; Argentina. Universidad Nacional del Sur. Departamento de AgronomĂa; ArgentinaFil: Gallardo, Jimena Alicia. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - BahĂa Blanca. Centro de Recursos Naturales Renovables de la Zona SemiĂĄrida. Universidad Nacional del Sur. Centro de Recursos Naturales Renovables de la Zona SemiĂĄrida; Argentina. Universidad Nacional del Sur. Departamento de AgronomĂa; ArgentinaFil: Carballo, JosĂ©. Universidad Nacional del Sur. Departamento de AgronomĂa; Argentina. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - BahĂa Blanca. Centro de Recursos Naturales Renovables de la Zona SemiĂĄrida. Universidad Nacional del Sur. Centro de Recursos Naturales Renovables de la Zona SemiĂĄrida; ArgentinaFil: Meier, Mauro SebastiĂĄn. Asociacion de Cooperativas Argentinas.; Argentina. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas; ArgentinaFil: Rodrigo, Juan Manuel. Universidad Nacional del Sur. Departamento de AgronomĂa; Argentina. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - BahĂa Blanca. Centro de Recursos Naturales Renovables de la Zona SemiĂĄrida. Universidad Nacional del Sur. Centro de Recursos Naturales Renovables de la Zona SemiĂĄrida; ArgentinaFil: Gallo, Cristian AndrĂ©s. Universidad Nacional del Sur. Departamento de AgronomĂa; Argentina. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - BahĂa Blanca. Centro de Recursos Naturales Renovables de la Zona SemiĂĄrida. Universidad Nacional del Sur. Centro de Recursos Naturales Renovables de la Zona SemiĂĄrida; ArgentinaFil: Selva, Juan Pablo. Universidad Nacional del Sur. Departamento de AgronomĂa; Argentina. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - BahĂa Blanca. Centro de Recursos Naturales Renovables de la Zona SemiĂĄrida. Universidad Nacional del Sur. Centro de Recursos Naturales Renovables de la Zona SemiĂĄrida; ArgentinaFil: Stein, Juliana. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - Rosario. Instituto de Investigaciones en Ciencias Agrarias de Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Agrarias. Instituto de Investigaciones en Ciencias Agrarias de Rosario; ArgentinaFil: Ortiz, Juan Pablo Amelio. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - Rosario. Instituto de Investigaciones en Ciencias Agrarias de Rosario. Universidad Nacional de Rosario. Facultad de Ciencias Agrarias. Instituto de Investigaciones en Ciencias Agrarias de Rosario; ArgentinaFil: Albertini, Emidio. UniversitĂ di Perugia; ItaliaFil: Echenique, Carmen Viviana. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - BahĂa Blanca. Centro de Recursos Naturales Renovables de la Zona SemiĂĄrida. Universidad Nacional del Sur. Centro de Recursos Naturales Renovables de la Zona SemiĂĄrida; Argentina. Universidad Nacional del Sur. Departamento de AgronomĂa; Argentin
DefiniçÔes para a padronização da pesquisa de auto-anticorpos contra constituintes do nĂșcleo (FAN HEp-2), nuclĂ©olo, citoplasma e aparelho mitĂłtico e suas associaçÔes clĂnicas
OBJECTIVE: The Second Brazilian Consensus on Antinuclear Antibodies (ANA) in HEp-2 Cells approved and extended the decision trees developed during the First Brazilian Consensus in order to also offer information about mixed patterns of fluorescence. METHODS: Since this test elicits reactions not only to nuclear autoimmune antigens but also to different cell compartments, new denominations for the test were approved. Results and CONCLUSIONS: These new denominations encompass variations on the autoantibody testing against the nucleus (ANA HEp-2), nucleolus, cytoplasm, and mitotic apparatus issue. Furthermore, major clinical associations were described for each immunofluorescent pattern, facilitating the interpretation of laboratory results in the clinical practice.OBJETIVO: O Segundo Consenso Brasileiro de Fator Antinuclear (FAN) em CĂ©lulas HEp-2 ratificou os algoritmos de decisĂŁo para leitura dos padrĂ”es do FAN na imunofluorescĂȘncia indireta vistos na primeira edição do Consenso Brasileiro, adicionando ainda um novo algoritmo relacionado com os padrĂ”es mistos. MĂTODOS: Tendo em vista a habilidade do teste em detectar autoantĂgenos nos distintos compartimentos celulares, e nĂŁo apenas no nĂșcleo, propĂ”e-se novas denominaçÔes para este exame laboratorial. RESULTADOS E CONCLUSĂES: Como novas denominaçÔes algumas sugestĂ”es foram igualmente aceitas, dentro do tema pesquisa de auto-anticorpos contra constituintes do nĂșcleo (FAN HEp-2), nuclĂ©olo, citoplasma e aparelho mitĂłtico. Foram abordadas as principais relevĂąncias clĂnicas com os padrĂ”es de FAN descritos, facilitando o melhor uso do ensaio pelo mĂ©dico.FMUSPUNIFESPBio-Rad LaboratĂłrio BrasilHospital Geral de GoiĂąniaBiomĂ©dicaUniversidade Federal de UberlĂąndiaUFMG HCPUCRS HCNew Life Produtos HospitalaresUniversidade CatĂłlica de GoiĂĄsFMUSP HC LaboratĂłrio CentralPatologista ClĂnicaFMUSP HCFrischmann Aisengart Unidad InmunologĂaUniversidade CatĂłlica de GoiĂĄs LaboratĂłrio de Auto-ImunidadeExame Medicina LaboratorialFMUFG HC LaboratĂłrio de Imuno-Reumatologia e HLALab. Santa LuziaMedivax/BionHSPE/SPUniversidade CatĂłlica de GoiĂĄs LaboratĂłrio da Ărea de SaĂșdeFarmacĂȘutica-BioquĂmicaUniv. Fed. Mato GrossoFMUFG Serviço de ReumatologiaHospital Durand Unidad InmunologĂaLaboratĂłrio ClĂnicoUFRGS HCPA Serviço de ReumatologiaUERJ FCMUFMG FMHospital UniversitĂĄrio de BrasĂlia LaboratĂłrio de ReumatologiaUNIFESPSciEL
Ciencias de la BiologĂa y AgronomĂa
Este volumen I contiene 17 capĂtulos arbitrados que se ocupan de estos asuntos en TĂłpicos Selectos de Ciencias de la BiologĂa y AgronomĂa, elegidos de entre las contribuciones, reunimos algunos investigadores y estudiantes. Se presenta un Estudio Comparativo de los Recursos HidrolĂłgico-Forestales de la Microcuenca de la Laguna de Epatlan, Pue. (1993 a 2014); la SituaciĂłn Actual de la Mancha de Asfalto en MaĂz (Zea mays L.) en los Municipios de Jiquipilas y Ocozocoautla, Chiapas, MĂ©xico; las poblaciones sobresalientes de maĂz de la raza Zapalote Chico, en la RegiĂłn Istmeña de Oaxaca; Se indica el Ăndice de ĂĄrea foliar de cultivo de Chile Poblano mediante dos mĂ©todos en condiciones protegidas; Esquivel, UrzĂșa y RamĂrez exploran el efecto de la biofertilizaciĂłn con Azospirillum en el crecimiento y producciĂłn de Jitomate; esbozan su artĂculo sobre la determinaciĂłn del nivel de Heterosis en hĂbridos de MaĂz para la Comarca Lagunera; una investigaciĂłn sobre la estabilizaciĂłn de semilla de Solanum lycopersicum durante el almacenamiento y estimulaciĂłn de la germinaciĂłn; acotan sobre el CTAB como una nueva opciĂłn para la detecciĂłn de Huanglongbing en cĂtricos, plantean su evaluaciĂłn sobre el aluminio y cĂłmo afecta la vida de florero de Heliconia psittacorum; indican sobre el impacto del H-564C, como un hĂbrido de maĂz con alta calidad de proteina para el trĂłpico hĂșmedo de MĂ©xico; presetan su investigaciĂłn sobre la producciĂłn de Piña Cayena Lisa y MD2 (Ananas comosus L.) en condiciones de Loma Bonita, en Oaxaca; acotan sobre el efecto de coberteras como control biolĂłgico por conservaciĂłn contra ĂĄfidos en Nogal Pecanero; esbozan sobre la caracterizaciĂłn de cuatro genotipos de Frijol Negro en MartĂnez de la Torre, Veracruz, MĂ©xico; presentan una caracterizaciĂłn hidroecolĂłgica de la microcuenca de Arroyo Prieto, YurirĂa, Gto., y alternativas para su restauraciĂłn ambiental; presentan su investigaciĂłn sobre el efecto del hongo Beauveria bassiana sobre solubilizaciĂłn de fosfatos y la disponibilidad de fĂłsforo en el suelo; plantean su investigaciĂłn sobre la GerminaciĂłn y regeneraciĂłn in vitro de Epidendrum falcatum LINDL; esbozan su artĂculo sobre genotipos de frijol negro y su tolerancia a sequĂa terminal en Veracruz, MĂ©xico
Identification of Phosphoproteins as Possible Differentiation Markers in All-Trans-Retinoic Acid-Treated Neuroblastoma Cells
BACKGROUND: Neuroblastic tumors account for 9-10% of pediatric tumors and neuroblastoma (NB) is the first cause of death in pre-school age children. NB is classified in four stages, depending on the extent of spreading. A fifth type of NB, so-called stage 4S (S for special), includes patients with metastatic tumors but with an overall survival that approximates 75% at five years. In most of these cases, the tumor regresses spontaneously and regression is probably associated with delayed neuroblast cell differentiation. METHODOLOGY/PRINCIPAL FINDINGS: In order to identify new early markers to follow and predict this process for diagnostic and therapeutics intents, we mimicked the differentiation process treating NB cell line SJ-NK-P with all-trans-retinoic acid (ATRA) at different times; therefore the cell proteomic pattern by mass spectrometry and the phosphoproteomic pattern by a 2-DE approach coupled with anti-phosphoserine and anti-phosphotyrosine western blotting were studied. CONCLUSIONS/SIGNIFICANCE: Proteomic analysis identified only two proteins whose expression was significantly different in treated cells versus control cells: nucleoside diphosphate kinase A (NDKA) and reticulocalbin-1 (RCN1), which were both downregulated after 9 days of ATRA treatment. However, phosphoproteomic analysis identified 8 proteins that were differentially serine-phosphorylated and 3 that were differentially tyrosine-phosphorylated after ATRA treatment. All proteins were significantly regulated (at least 0.5-fold down-regulated). Our results suggest that differentially phosphorylated proteins could be considered as more promising markers of differentiation for NB than differentially expressed proteins
FSR 1716: A New Milky Way Globular Cluster Confirmed Using VVV RR Lyrae Stars
We use deep multi-epoch near-IR images of the VISTA Variables in the VĂa LĂĄctea (VVV) Survey to search for RR Lyrae stars toward the Southern Galactic plane. Here, we report the discovery of a group of RR Lyrae stars close together in VVV tile d025. Inspection of the VVV images and PSF photometry reveals that most of these stars are likely to belong to a globular cluster that matches the position of the previously known star cluster FSR 1716. The stellar density map of the field yields a >100? detection for this candidate globular cluster that is centered at equatorial coordinates R.A. J2000 = 16:10:30.0, decl. J2000 = ?53:44:56 and galactic coordinates l = 329.77812, b = ?1.59227. The colorâmagnitude diagram of this object reveals a well-populated red giant branch, with a prominent red clump at K s = 13.35 ± 0.05, and J ? K s = 1.30 ± 0.05. We present the cluster RR Lyrae positions, magnitudes, colors, periods, and amplitudes. The presence of RR Lyrae indicates an old globular cluster, with an age >10 Gyr. We classify this object as an Oosterhoff type I globular cluster, based on the mean period of its RR Lyrae type ab, days, and argue that this is a relatively metal-poor cluster with [Fe/H] = ?1.5 ± 0.4 dex. The mean extinction and reddening for this cluster are and E(J ? K s ) = 0.72 ± 0.02 mag, respectively, as measured from the RR Lyrae colors and the near-IR colorâmagnitude diagram. We also measure the cluster distance using the RR Lyrae type ab stars. The cluster mean distance modulus is (m ? M)0 = 14.38 ± 0.03 mag, implying a distance D = 7.5 ± 0.2 kpc and a Galactocentric distance R G = 4.3 kpc
Light (anti)nuclei production in Pb-Pb collisions at sNN=5.02Â TeV
The measurement of the production of deuterons, tritons and 3 He and their antiparticles in Pb-Pb collisions
at âs NN = 5.02 TeV is presented in this article. The measurements are carried out at midrapidity (|y| <
0.5) as a function of collision centrality using the ALICE detector. The pT -integrated yields, the coalescence
parameters and the ratios to protons and antiprotons are reported and compared with nucleosynthesis models. The
comparison of these results in different collision systems at different center-of-mass collision energies reveals a
suppression of nucleus production in small systems. In the Statistical Hadronisation Model framework, this can
be explained by a small correlation volume where the baryon number is conserved, as already shown in previous
fluctuation analyses. However, a different size of the correlation volume is required to describe the proton yields
in the same data sets. The coalescence model can describe this suppression by the fact that the wave functions
of the nuclei are large and the fireball size starts to become comparable and even much smaller than the actual
nucleus at low multiplicities
Inclusive and multiplicity dependent production of electrons from heavy-flavour hadron decays in pp and p-Pb collisions
Measurements of the production of electrons from heavy-flavour hadron decays in pp collisions at root s = 13 TeV at midrapidity with the ALICE detector are presented down to a transverse momentum (p(T)) of 0.2 GeV/c and up to p(T) = 35 GeV/c, which is the largest momentum range probed for inclusive electron measurements in ALICE. In p-Pb collisions, the production cross section and the nuclear modification factor of electrons from heavy-flavour hadron decays are measured in the p(T) range 0.5 < p(T) < 26 GeV/c at root s(NN) = 8.16 TeV. The nuclear modification factor is found to be consistent with unity within the statistical and systematic uncertainties. In both collision systems, first measurements of the yields of electrons from heavy-flavour hadron decays in different multiplicity intervals normalised to the multiplicity-integrated yield (self-normalised yield) at midrapidity are reported as a function of the self-normalised charged-particle multiplicity estimated at midrapidity. The self-normalised yields in pp and p-Pb collisions grow faster than linear with the self-normalised multiplicity. A strong p(T) dependence is observed in pp collisions, where the yield of high-p(T) electrons increases faster as a function of multiplicity than the one of low-p(T) electrons. The measurement in p-Pb collisions shows no p(T) dependence within uncertainties. The self-normalised yields in pp and p-Pb collisions are compared with measurements of other heavy-flavour, light-flavour, and strange particles, and with Monte Carlo simulations
Production of pions, kaons, and protons as a function of the relative transverse activity classifier in pp collisions at = 13 TeV
Abstract: The production of ϱ, K±, and ( p )p is measured in pp collisions at âs = 13 TeV
in different topological regions of the events. Particle transverse momentum (pT) spectra are
measured in the âtowardâ, âtransverseâ, and âawayâ angular regions defined with respect
to the direction of the leading particle in the event. While the toward and away regions
contain the fragmentation products of the near-side and away-side jets, respectively, the
transverse region is dominated by particles from the Underlying Event (UE). The relative
transverse activity classifier, RT = NT/ăNTă, is used to group events according to their UE
activity, where NT is the measured charged-particle multiplicity per event in the transverse
region and ăNTă is the mean value over all the analysed events. The first measurements
of identified particle pT spectra as a function of RT in the three topological regions are
reported. It is found that the yield of high transverse momentum particles relative to the
RT-integrated measurement decreases with increasing RT in both the toward and the away
regions, indicating that the softer UE dominates particle production as RT increases and
validating that RT can be used to control the magnitude of the UE. Conversely, the spectral
shapes in the transverse region harden significantly with increasing RT. This hardening
follows a mass ordering, being more significant for heavier particles. Finally, it is observed
that the pT-differential particle ratios (p + p )/(Ï+ + Ïâ) and (K+ + Kâ)/(Ï+ + Ïâ) in
the low UE limit (RT â 0) approach expectations from Monte Carlo generators such as
PYTHIA 8 with Monash 2013 tune and EPOS LHC, where the jet-fragmentation models
have been tuned to reproduce e+eâ results
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