1,246 research outputs found

    Creating AI characters for fighting games using genetic programming

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    This paper proposes a character generation approach for the M.U.G.E.N. fighting game that can create engaging AI characters using a computationally cheap process without the intervention of the expert developer. The approach uses a Genetic Programming algorithm that refines randomly generated character strategies into better ones using tournament selection. The generated AI characters were tested by twenty-seven human players and were rated according to results, perceived difficulty and how engaging the gameplay was. The main advantages of this procedure are that no prior knowledge of how to code the strategies of the AI character is needed and there is no need to interact with the internal code of the game. In addition, the procedure is capable of creating a wide diversity of players with different strategic skills, which could be potentially used as a starting point to a further adaptive process

    Primary Ciliary Dyskinesia:Integrating Genetics into Clinical Practice

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    Purpose of Review: Advances in molecular genetics have improved our understanding of primary ciliary dyskinesia. The purpose of this review is to describe the integration of genetics into clinical practice.Recent Findings: This review describes > 50 genes which have been identified to cause multiple motile ciliopathies. Known genotype–phenotype relationships are explored, including genes associated with worse prognosis (CCDC39, CCDC40, CCNO). Features which indicate referral for genetic testing such as a family history, situs defects and lifelong chronic upper and lower respiratory tract disease are described along with how genetics fits into current guidelines for diagnostic algorithms, and the potential challenges and advantages.Summary: As we move forward, the growing genomic knowledge about primary ciliary dyskinesia will aid diagnosis, understanding of prognosis and the establishment of future therapeutic trials

    Primary Ciliary Dyskinesia:Integrating Genetics into Clinical Practice

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    Purpose of Review: Advances in molecular genetics have improved our understanding of primary ciliary dyskinesia. The purpose of this review is to describe the integration of genetics into clinical practice.Recent Findings: This review describes > 50 genes which have been identified to cause multiple motile ciliopathies. Known genotype–phenotype relationships are explored, including genes associated with worse prognosis (CCDC39, CCDC40, CCNO). Features which indicate referral for genetic testing such as a family history, situs defects and lifelong chronic upper and lower respiratory tract disease are described along with how genetics fits into current guidelines for diagnostic algorithms, and the potential challenges and advantages.Summary: As we move forward, the growing genomic knowledge about primary ciliary dyskinesia will aid diagnosis, understanding of prognosis and the establishment of future therapeutic trials

    A class of quadratic deformations of Lie superalgebras

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    We study certain Z_2-graded, finite-dimensional polynomial algebras of degree 2 which are a special class of deformations of Lie superalgebras, which we call quadratic Lie superalgebras. Starting from the formal definition, we discuss the generalised Jacobi relations in the context of the Koszul property, and give a proof of the PBW basis theorem. We give several concrete examples of quadratic Lie superalgebras for low dimensional cases, and discuss aspects of their structure constants for the `type I' class. We derive the equivalent of the Kac module construction for typical and atypical modules, and a related direct construction of irreducible modules due to Gould. We investigate in detail one specific case, the quadratic generalisation gl_2(n/1) of the Lie superalgebra sl(n/1). We formulate the general atypicality conditions at level 1, and present an analysis of zero-and one-step atypical modules for a certain family of Kac modules.Comment: 26pp, LaTeX. Original title: "Finite dimensional quadratic Lie superalgebras"; abstract re-worded; text clarified; 3 references added; rearrangement of minor appendices into text; new subsection 4.

    Unrelated Helpers in a Primitively Eusocial Wasp: Is Helping Tailored Towards Direct Fitness?

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    The paper wasp Polistes dominulus is unique among the social insects in that nearly one-third of co-foundresses are completely unrelated to the dominant individual whose offspring they help to rear and yet reproductive skew is high. These unrelated subordinates stand to gain direct fitness through nest inheritance, raising the question of whether their behaviour is adaptively tailored towards maximizing inheritance prospects. Unusually, in this species, a wealth of theory and empirical data allows us to predict how unrelated subordinates should behave. Based on these predictions, here we compare helping in subordinates that are unrelated or related to the dominant wasp across an extensive range of field-based behavioural contexts. We find no differences in foraging effort, defense behaviour, aggression or inheritance rank between unrelated helpers and their related counterparts. Our study provides no evidence, across a number of behavioural scenarios, that the behaviour of unrelated subordinates is adaptively modified to promote direct fitness interests

    Location and group size influence decisions in simulated intergroup encounters in banded mongooses

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    In social species that cooperatively defend territories the decision to retreat or attack in contests between groups is likely to depend on ecological and social factors. Previous studies have emphasized the importance of the encounter location or the size of competing groups on the outcome. In addition, the identity of the intruder, whether familiar or stranger, may also play a role. To test whether the same factors affect the resident group's decisions already at the beginning of contests, we simulated intergroup encounters in banded mongooses (Mungos mungo). When spotting rival groups banded mongooses emit "screeching calls” which lead group members to bunch up. With playbacks of these calls, we tested how the groups' response was affected by the following factors: 1) the location of the playback in relation to their territory (exclusive use vs. overlap); 2) the number of resident individuals; and 3) the origin of calls (neighbor vs. stranger) used. Subjects were more likely to approach the loudspeakers and arrive within 1 m of the speakers in the exclusive use zone than in the overlap zone. Moreover, larger groups tended to be more likely to move toward the loudspeakers and were also more likely to arrive there. The origin of calls used in the playbacks did not affect the groups' responses. These findings exemplify the importance of the combined effect of location and group size on group decisions during impending intergroup contes

    Separate processing of texture and form in the ventral stream : evidence from fMRI and visual agnosia.

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    Real-life visual object recognition requires the processing of more than just geometric (shape, size, and orientation) properties. Surface properties such as color and texture are equally important, particularly for providing information about the material properties of objects. Recent neuroimaging research suggests that geometric and surface properties are dealt with separately, within the lateral occipital cortex (LOC) and the collateral sulcus (CoS), respectively. Here we compared objects that either differed in aspect ratio or in surface texture only, keeping all other visual properties constant. Results on brain-intact participants confirmed that surface texture activates an area in the posterior CoS, quite distinct from the area activated by shape within LOC. We also tested two patients with visual object agnosia, one of whom (DF) performed well on the texture task but at chance on the shape task, while the other (MS) showed the converse pattern. This behavioral double dissociation was matched by a parallel neuroimaging dissociation, with activation in CoS but not LOC in patient DF, and activation in LOC but not CoS in patient MS. These data provide presumptive evidence that the areas respectively activated by shape and texture play a causally necessary role in the perceptual discrimination of these features
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