Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.

BACKGROUND: The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry. METHODS AND RESULTS: A total of 52,014 patients with newly diagnosed AF were enrolled globally; of these, 1388 patients were recruited from 26 sites within India (2012-2016). In India, the mean age was 65.8 years at diagnosis of NVAF. Hypertension was the most prevalent risk factor for AF, present in 68.5% of patients from India and in 76.3% of patients globally (P < 0.001). Diabetes and coronary artery disease (CAD) were prevalent in 36.2% and 28.1% of patients as compared with global prevalence of 22.2% and 21.6%, respectively (P < 0.001 for both). Antiplatelet therapy was the most common antithrombotic treatment in India. With increasing stroke risk, however, patients were more likely to receive oral anticoagulant therapy [mainly vitamin K antagonist (VKA)], but average international normalized ratio (INR) was lower among Indian patients [median INR value 1.6 (interquartile range {IQR}: 1.3-2.3) versus 2.3 (IQR 1.8-2.8) (P < 0.001)]. Compared with other countries, patients from India had markedly higher rates of all-cause mortality [7.68 per 100 person-years (95% confidence interval 6.32-9.35) vs 4.34 (4.16-4.53), P < 0.0001], while rates of stroke/systemic embolism and major bleeding were lower after 1 year of follow-up. CONCLUSION: Compared to previously published registries from India, the GARFIELD-AF registry describes clinical profiles and outcomes in Indian patients with AF of a different etiology. The registry data show that compared to the rest of the world, Indian AF patients are younger in age and have more diabetes and CAD. Patients with a higher stroke risk are more likely to receive anticoagulation therapy with VKA but are underdosed compared with the global average in the GARFIELD-AF. CLINICAL TRIAL REGISTRATION-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362

The LHCb upgrade I

The LHCb upgrade represents a major change of the experiment. The detectors have been almost completely renewed to allow running at an instantaneous luminosity five times larger than that of the previous running periods. Readout of all detectors into an all-software trigger is central to the new design, facilitating the reconstruction of events at the maximum LHC interaction rate, and their selection in real time. The experiment's tracking system has been completely upgraded with a new pixel vertex detector, a silicon tracker upstream of the dipole magnet and three scintillating fibre tracking stations downstream of the magnet. The whole photon detection system of the RICH detectors has been renewed and the readout electronics of the calorimeter and muon systems have been fully overhauled. The first stage of the all-software trigger is implemented on a GPU farm. The output of the trigger provides a combination of totally reconstructed physics objects, such as tracks and vertices, ready for final analysis, and of entire events which need further offline reprocessing. This scheme required a complete revision of the computing model and rewriting of the experiment's software

CdSxSe1-x nanocrystals in a silicate glass

A dilute system of CdSxSe1-x nanocrystals with low anisotropy and low size dispersion has been studied by SAXS. The presence of angularities at the surface of the nanoparticles is evidenced from the limit at zero of the chord distribution function. Moreover in a model of spherical particles the size given by the average chord does not agree with that given by the integral parameters. A cubic particle shape has been used to evaluation of the size distribution. This distribution agrees with the expected one, and allows to confirm the validity of a polyedral model for the treatment of the SAXS data. Structural information on the particle surface can be deduced from the presence of the angularities

ETUDE DU GONFLEMENT PAR L'EAU DE SMECTITES DIOCTAEDRIQUES

Pas de Résumé disponibl

Generic Scene Recovery using Multiple Images

Abstract. In this paper, a generative model based method for recovering both the shape and the reflectance of the surface(s) of a scene from multiple images is presented, assuming that illumination conditions are known in advance. Based on a variational framework and via gradient descents, the algorithm minimizes simultaneously and consistently a global cost functional with respect to both shape and reflectance. Contrary to previous works which consider specific individual scenarios, our method applies to a number of scenarios – mutiview stereovision, multiview photometric stereo, and multiview shape from shading. In addition, our approach naturally combines stereo, silhouette and shading cues in a single framework and, unlike most previous methods dealing with only Lambertian surfaces, the proposed method considers general dichromatic surfaces. 1 Introduction and Related Work Many methods have been proposed to recover the three-dimensional surface shape using multiple images during these last two decades [1]. On the other hand, for a long time, the estimation of surface radiance/reflectance was secondary. Even some recen