539 research outputs found
Nonsmooth Optimization; Proceedings of an IIASA Workshop, March 28 - April 8, 1977
Optimization, a central methodological tool of systems analysis, is used in many of IIASA's research areas, including the Energy Systems and Food and Agriculture Programs. IIASA's activity in the field of optimization is strongly connected with nonsmooth or nondifferentiable extreme problems, which consist of searching for conditional or unconditional minima of functions that, due to their complicated internal structure, have no continuous derivatives. Particularly significant for these kinds of extreme problems in systems analysis is the strong link between nonsmooth or nondifferentiable optimization and the decomposition approach to large-scale programming.
This volume contains the report of the IIASA workshop held from March 28 to April 8, 1977, entitled Nondifferentiable Optimization. However, the title was changed to Nonsmooth Optimization for publication of this volume as we are concerned not only with optimization without derivatives, but also with problems having functions for which gradients exist almost everywhere but are not continous, so that the usual gradient-based methods fail.
Because of the small number of participants and the unusual length of the workshop, a substantial exchange of information was possible. As a result, details of the main developments in nonsmooth optimization are summarized in this volume, which might also be considered a guide for inexperienced users. Eight papers are presented: three on subgradient optimization, four on descent methods, and one on applicability. The report also includes a set of nonsmooth optimization test problems and a comprehensive bibliography
Computing Economic Equilibria through Nonsmooth Optimization
In the first section the problem of nonsmooth optimization is described in general terms, setting the precise hypothesis in mathematical language. Section 2 describes the principles of an example which arises in the context of the linkage of national models of food and agriculture. The general methodology is presented in Section 3, where the algorithm of solution is outlined. Section 4 reports on an extensive set of numerical experiments, both on problems known in the literature, and on the example of Section 2. Finally the paper concludes with some remarks about improvements of the algorithm, which motivate further research on the subject
High sensitivity measurement of 224Ra and 226Ra in water with an improved hydrous titanium oxide technique at the Sudbury Neutrino Observatory
The existing hydrous titanium oxide (HTiO) technique for the measurement of
224Ra and 226Ra in the water at the Sudbury Neutrino Observatory (SNO) has been
changed to make it faster and less sensitive to trace impurities in the HTiO
eluate. Using HTiO-loaded filters followed by cation exchange adsorption and
HTiO co-precipitation, Ra isotopes from 200-450 tonnes of heavy water can be
extracted and concentrated into a single sample of a few millilitres with a
total chemical efficiency of 50%. Combined with beta-alpha coincidence
counting, this method is capable of measuring 2.0x10^3 uBq/kg of 224Ra and
3.7x10^3 uBq/kg of 226Ra from the 232Th and 238U decay chains, respectively,
for a 275 tonne D2O assay, which are equivalent to 5x10^16 g Th/g and 3x10^16 g
U/g in heavy water.Comment: 8 Pages, 2 figures and 2 table
Embodying compassion: A systematic review of the views of nurses and patients
© 2018 John Wiley & Sons Ltd Aims and objectives: To provide a review of empirical research investigating how compassion is expressed by nurses and received by patients in hospital settings. Background: Compassion is viewed as an important and fundamental part of a health professional practice. Universally, reports from both media and government agencies have addressed perceived deficits of compassion in healthcare with nurses accused of a lack of compassion. Research into compassion to date has largely focused on the problematic nature of compassion such as burnout, fatigue and other negative personal and work-related outcomes. Design: A systematic literature review of empirical research guided by a meta-ethnographic approach supported the systematic comparison and translation of the included studies. Six online databases were searched from January 2006–December 2016. Methods: This review was carried out according to the PRISMA-P reporting guidelines. How compassion in healthcare was defined was extracted alongside findings on how compassion was expressed by nurses and received by patients. Synthesis of the research was completed resulting in new interpretations. Results: Eleven papers met the inclusion criteria and were included in the review. Multiple differing definitions of compassion in healthcare were applied. Nurses embody and enact compassion through behaviours such as spending time with patients and communicating effectively with patients. Patients experience compassion through a sense of togetherness with nurses. Conclusion: Existing research demonstrated dissonance between the expression of compassion by nurses and how compassion is experienced by patients. The themes identified in this review should be considered by health professionals providing patient care. Relevance to clinical practice: Health providers should acknowledge and account for the time that nurses need with patients to demonstrate compassion in practice. Nursing education relating to the expression of compassion should articulate both the subjectivity and ambiguity of the term and examine the relationship between compassion and suffering
Measurement of 222Rn dissolved in water at the Sudbury Neutrino Observatory
The technique used at the Sudbury Neutrino Observatory (SNO) to measure the
concentration of 222Rn in water is described. Water from the SNO detector is
passed through a vacuum degasser (in the light water system) or a membrane
contact degasser (in the heavy water system) where dissolved gases, including
radon, are liberated. The degasser is connected to a vacuum system which
collects the radon on a cold trap and removes most other gases, such as water
vapor and nitrogen. After roughly 0.5 tonnes of H2O or 6 tonnes of D2O have
been sampled, the accumulated radon is transferred to a Lucas cell. The cell is
mounted on a photomultiplier tube which detects the alpha particles from the
decay of 222Rn and its daughters. The overall degassing and concentration
efficiency is about 38% and the single-alpha counting efficiency is
approximately 75%. The sensitivity of the radon assay system for D2O is
equivalent to ~3 E(-15) g U/g water. The radon concentration in both the H2O
and D2O is sufficiently low that the rate of background events from U-chain
elements is a small fraction of the interaction rate of solar neutrinos by the
neutral current reaction.Comment: 14 pages, 6 figures; v2 has very minor change
The Radius of Metric Subregularity
There is a basic paradigm, called here the radius of well-posedness, which
quantifies the "distance" from a given well-posed problem to the set of
ill-posed problems of the same kind. In variational analysis, well-posedness is
often understood as a regularity property, which is usually employed to measure
the effect of perturbations and approximations of a problem on its solutions.
In this paper we focus on evaluating the radius of the property of metric
subregularity which, in contrast to its siblings, metric regularity, strong
regularity and strong subregularity, exhibits a more complicated behavior under
various perturbations. We consider three kinds of perturbations: by Lipschitz
continuous functions, by semismooth functions, and by smooth functions,
obtaining different expressions/bounds for the radius of subregularity, which
involve generalized derivatives of set-valued mappings. We also obtain
different expressions when using either Frobenius or Euclidean norm to measure
the radius. As an application, we evaluate the radius of subregularity of a
general constraint system. Examples illustrate the theoretical findings.Comment: 20 page
Appetite and gut hormone responses to moderate-intensity continuous exercise versus high-intensity interval exercise, in normoxic and hypoxic conditions.
This study investigated the effects of continuous moderate-intensity exercise (MIE) and high-intensity interval exercise (HIIE) in combination with short exposure to hypoxia on appetite and plasma concentrations of acylated ghrelin, peptide YY (PYY), and glucagon-like peptide-1 (GLP-1). Twelve healthy males completed four, 2.6 h trials in a random order: 1) MIE-normoxia, 2) MIE-hypoxia, 3) HIIE-normoxia, and 4) HIIE-hypoxia. Exercise took place in an environmental chamber. During MIE, participants ran for 50 min at 70% of altitude-specific maximal oxygen uptake ( 2max) and during HIIE performed 6 x 3 min running at 90% 2max interspersed with 6 x 3 min active recovery at 50% 2max with a 7 min warm-up and cool-down at 70% 2max (50 min total). In hypoxic trials, exercise was performed at a simulated altitude of 2,980 m (14.5% O2). Exercise was completed after a standardised breakfast. A second meal standardised to 30% of participants’ daily energy requirements was provided 45 min after exercise. Appetite was suppressed more in hypoxia than normoxia during exercise, post-exercise, and for the full 2.6 h trial period (linear mixed modelling, p 0.05). These findings demonstrate that short exposure to hypoxia causes suppressions in appetite and plasma acylated ghrelin concentrations. Furthermore, appetite responses to exercise do not appear to be influenced by exercise modality
Enteric Neurospheres Are Not Specific to Neural Crest Cultures: Implications for Neural Stem Cell Therapies
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited
A Search for Neutrinos from the Solar hep Reaction and the Diffuse Supernova Neutrino Background with the Sudbury Neutrino Observatory
A search has been made for neutrinos from the hep reaction in the Sun and from the diffus
- …