1,140 research outputs found
Foundations in Wisconsin: A Directory [22nd ed. 2003]
This 22nd edition of Foundations in Wisconsin (2003) is the first produced by the new Marquette University John P. Raynor, S.J., Library. The directory is designed as a research tool for grantseekers interested in locating information on private, corporate, and community foundations registered in Wisconsin. Each entry in this new edition has been updated or reviewed to provide the most current information available. Most of the data was extracted from IRS 990-PF tax returns filed by the foundations. However, additional information was obtained from surveys, annual reports, and foundation Web sites.
The economy has slowed the growth of Wisconsin foundations. While the number of active foundations grew to 1160 (up slightly from 1151 last year), other areas are showing decline. For the first time in 23 years of reporting, both grants and assets decreased rather than increased. Grants decreased by .6% as compared to last year’s increase of 7.7%. Assets declined by 6.3%, down from the .3% increase documented in 2002. The following table illustrates the financial pattern over the last 10 editions.https://epublications.marquette.edu/lib_fiw/1008/thumbnail.jp
Formation of public strategic planning in Ukraine
It is sometimes the case that a theory proposes that the population means on two variables should have the same rank order across a set of experimental conditions. This paper presents a test of this hypothesis. The test statistic is based on the coupled monotonic regression algorithm developed by the authors. The significance of the test statistic is determined by comparison to an empirical distribution specific to each case, obtained via non-parametric or semi-parametric bootstrap. We present an analysis of the power and Type I error control of the test based on numerical simulation. Partial order constraints placed on the variables may sometimes be theoretically justified. These constraints are easily incorporated into the computation of the test statistic and are shown to have substantial effects on power. The test can be applied to any form of data, as long as an appropriate statistical model can be specified.free access is valid until January 8, 2016:http://authors.elsevier.com/a/1S3XC53naPWGhFunding agencies: Australian Research Council [0877510, 0878630, 110100751, 130101535]; National Science Foundation [1256959]; Linkoping University</p
Combined effects of extrinsic and intrinsic factors on otolith chemistry: Implications for environmental reconstructions
Otolith chemistry is widely used to understand patterns of fish movement and habitat use, with significant progress made in understanding the influence of environmental factors on otolith elemental uptake. However, few studies consider the interactive effect that environmental and genetic influences have on otolith chemistry. This study assessed the influence of salinity, temperature, and genetics on the incorporation of three key elements (strontium (Sr), barium (Ba), and magnesium (Mg)) into the otoliths of two discrete stocks of mulloway (Argyrosomus japonicus) fingerlings reared in captivity. Elemental analysis via laser ablation inductively coupled – plasma mass spectrometry found that stock (genetics) had a significant interactive effect on otolith Sr:Ca (salinity × temperature × stock) and Ba:Ca (salinity × stock), but did not affect Mg:Ca incorporation. Mg:Ca showed a positive relationship with temperature for both stocks. The incorporation of some elements into the otoliths of fish is the result of complex interactions between extrinsic and intrinsic factors. These findings highlight the necessity to also consider stock along with environmental variables when using trace elemental signatures to reconstruct the environmental histories of fish.Thomas C. Barnes, Bronwyn M. Gillander
Twelve tips for teaching brief motivational interviewing to medical students
Background: Shifting from paternalistic to patient-centred doctor-patient relationships has seen a growing number of medical programs incorporate brief motivational interviewing training in their curriculum. Some medical educators, however, are unsure of precisely what, when, and how to incorporate such training. Aims: This article provides educators with 12 tips for teaching brief motivational interviewing to medical students, premised on evidence-based pedagogy. Methods: Tips were drawn from the literature and authors’ own experiences. Results: The 12 tips are: (1) Set clear learning objectives, (2) Select experienced educators, (3) Provide theoretical perspectives, (4) Share the evidence base, (5) Outline the “spirit”, principles, and sequence, (6) Show students what it looks like, (7) Give students a scaffold to follow, (8) Provide opportunities for skill practice, (9) Involve clinical students in teaching, (10) Use varied formative and summative assessments, (11) Integrate and maintain, and (12) Reflect and evaluate. Conclusions: We describe what to include and why, and outline when and how to teach the essential components of brief motivational interviewing knowledge and skills in a medical curriculum
Practical recognition tools of immunoglobulin G serum antibodies against the myelin oligodendrocyte glycoprotein‐positive optic neuritis and its clinical implications
Myelin oligodendrocyte glycoprotein (MOG)-associated disease is an autoimmune disease of the central nervous system, associated with the presence of immunoglobulin G serum antibodies against MOG. Recent data have allowed characterization of the clinical spectrum of MOG-associated disease, which is now considered a new disease entity, distinct from multiple sclerosis and neuromyelitis optica spectrum disorders. Optic neuritis is the most common clinical presentation of MOG-associated disease in adults, both at disease onset and during the disease course, and has several distinct clinical and paraclinical features. Immunoglobulin G serum antibodies against MOG-positive optic neuritis is often bilateral and associated with optic disc swelling and a longitudinally extensive abnormal magnetic resonance imaging signal involving the retrobulbar portion of the optic nerve. The visual acuity during the acute attack is severely decreased, and the response to corticosteroids is often rapid and prominent. However, early relapses after steroid cessation are common, and a subset of patients is left with a permanent visual disability. In this review, we discuss the clinical and paraclinical features of immunoglobulin G serum antibodies against MOG-positive optic neuritis in adults, and focus on the distinctive features that can enable its early diagnosis. Therapeutical considerations at the acute stage and for relapse prevention are further deliberated
Heme Oxygenase-1 Expression Affects Murine Abdominal Aortic Aneurysm Progression.
Heme oxygenase-1 (HO-1), the rate-limiting enzyme in heme degradation, is a cytoprotective enzyme upregulated in the vasculature by increased flow and inflammatory stimuli. Human genetic data suggest that a diminished HO-1 expression may predispose one to abdominal aortic aneurysm (AAA) development. In addition, heme is known to strongly induce HO-1 expression. Utilizing the porcine pancreatic elastase (PPE) model of AAA induction in HO-1 heterozygous (HO-1+/-, HO-1 Het) mice, we found that a deficiency in HO-1 leads to augmented AAA development. Peritoneal macrophages from HO-1+/- mice showed increased gene expression of pro-inflammatory cytokines, including MCP-1, TNF-alpha, IL-1-beta, and IL-6, but decreased expression of anti-inflammatory cytokines IL-10 and TGF-beta. Furthermore, treatment with heme returned AAA progression in HO-1 Het mice to a wild-type profile. Using a second murine AAA model (Ang II-ApoE-/-), we showed that low doses of the HMG-CoA reductase inhibitor rosuvastatin can induce HO-1 expression in aortic tissue and suppress AAA progression in the absence of lipid lowering. Our results support those studies that suggest that pleiotropic statin effects might be beneficial in AAA, possibly through the upregulation of HO-1. Specific targeted therapies designed to induce HO-1 could become an adjunctive therapeutic strategy for the prevention of AAA disease
Low-temperature tapered-fiber probing of diamond NV ensembles coupled to GaP microcavities
In this work we present a platform for testing the device performance of a
cavity-emitter system, using an ensemble of emitters and a tapered optical
fiber. This method provides high-contrast spectra of the cavity modes,
selective detection of emitters coupled to the cavity, and an estimate of the
device performance in the single- emitter case. Using nitrogen-vacancy (NV)
centers in diamond and a GaP optical microcavity, we are able to tune the
cavity onto the NV resonance at 10 K, couple the cavity-coupled emission to a
tapered fiber, and measure the fiber-coupled NV spontaneous emission decay.
Theoretically we show that the fiber-coupled average Purcell factor is 2-3
times greater than that of free-space collection; although due to ensemble
averaging it is still a factor of 3 less than the Purcell factor of a single,
ideally placed center.Comment: 15 pages, 6 figure
Fano Effect in a Few-Electron Quantum Dot
We have studied the Fano effect in a few-electron quantum dot side-coupled to
a quantum wire. The conductance of the wire, which shows an ordinal
staircase-like quantization without the dot, is modified through the
interference (the Fano effect) and the charging effects. These effects are
utilized to verify the exhaustion of electrons in the dot. The "addition energy
spectrum" of the dot shows a shell structure, indicating that the electron
confinement potential is fairly circular. A rapid sign inversion of the Fano
parameter on the first conductance plateau with the change of the wire gate
voltage has been observed, and explained by introducing a finite width of
dot-wire coupling.Comment: 11 pages, 7 figure
Structure, stability and stress properties of amorphous and nanostructured carbon films
Structural and mechanical properties of amorphous and nanocomposite carbon
are investigated using tight-binding molecular dynamics and Monte Carlo
simulations. In the case of amorphous carbon, we show that the variation of
sp^3 fraction as a function of density is linear over the whole range of
possible densities, and that the bulk moduli follow closely the power-law
variation suggested by Thorpe. We also review earlier work pertained to the
intrinsic stress state of tetrahedral amorphous carbon. In the case of
nanocomposites, we show that the diamond inclusions are stable only in dense
amorphous tetrahedral matrices. Their hardness is considerably higher than that
of pure amorphous carbon films. Fully relaxed diamond nanocomposites possess
zero average intrinsic stress.Comment: 10 pages, 6 figure
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