Precision surveying using very long baseline interferometry

Radio interferometry measurements were used to measure the vector baselines between large microwave radio antennas. A 1.24 km baseline in Massachusetts between the 36 meter Haystack Observatory antenna and the 18 meter Westford antenna of Lincoln Laboratory was measured with 5 mm repeatability in 12 separate experiments. Preliminary results from measurements of the 3,928 km baseline between the Haystack antenna and the 40 meter antenna at the Owens Valley Radio Observatory in California are presented

Synthesis and antiprotozoal activity of azabicyclo-nonane pyrimidine hybrids

2,4-Diaminopyrimidines and (dialkylamino)azabicyclo-nonanes possess activity against protozoan parasites. A series of fused hybrids were synthesized and tested in vitro against pathogens of malaria tropica and sleeping sickness. The activities and selectivities of compounds strongly depended on the substitution pattern of both ring systems as well as on the position of the nitrogen atom in the bicycles. The most promising hybrids of 3-azabicyclo-nonane with 2-aminopyrimidine showed activity against P. falciparum NF54 in submicromolar concentration and high selectivity. A hybrid with pyrrolidino substitution of the 2-azabicyclo-nonane as well as of the pyrimidine moiety exhibited promising activity against the multiresistant K1 strain of P. falciparum. A couple of hybrids of 2-azabicyclo-nonanes with 2-(dialkylamino)pyrimidines possessed high activity against Trypanosoma brucei rhodesiense STIB900 and good selectivity

Polar motion and UT1: Comparison of VLBI, lunar laser, satellite laser, satellite Doppler, and conventional astrometric determinations

Very long baseline interferometry observations made with a 3900 km baseline interferometer (Haystack Observatory in Massachusetts to Owens Valley Observation in California) were used to estimate changes in the X-component of the position of the Earth's pole and in UT1. These estimates are compared with corresponding ones from lunar laser ranging, satellite laser ranging, satellite Doppler, and stellar observations

Antiprotozoal activity of azabicyclo-nonanes linked to tetrazole or sulfonamide cores

N-(Aminoalkyl)azabicyclo[3.2.2]nonanes possess antiplasmodial and antitrypanosomal activity. A series with terminal tetrazole or sulfonamido partial structure was prepared. The structures of all new compounds were confirmed by NMR and IR spectroscopy and by mass spectral data. A single crystal structure analysis enabled the distinction between isomers. The antiprotozoal activities were examined in vitro against strains of Plasmodium falciparum and Trypanosoma brucei rhodesiense (STIB 900). The most active sulfonamide and tetrazole derivates showed activities in the submicromolar range

Application of very long baseline interferometry to Astrometry and Geodesy: effects of frequency standard instability on accuracy

The accuracy of geodetic and astrometric information obtained from very long baseline interferometry (VLBI) observations is dependent upon the stability of the frequency standard, or clock, used at each site of VLBI array. The sensitivities of two hydrogen maser frequency standards of different design to pressure, temperature, and magnetic field variations were measured; and, for one of the standards, sensitivity was found to be severe enough to degrade the information content of VLBI measurements. However, the effect on the geometric and astrometric information of such clock instabilities, with time scales of hours or greater, can be sharply reduced through the use of differencing techniques

Atmospheric temperature responses to solar irradiance and geomagnetic activity

The relative effects of solar irradiance and geomagnetic activity on the atmospheric temperature anomalies (Ta) are examined from the monthly to interdecadal timescales. Geomagnetic Ap (Ap) signals are found primarily in the stratosphere, while the solar F10.7-cm radio flux (Fs) signals are found in both the stratosphere and troposphere. In the troposphere, 0.1–0.4 K increases in Ta are associated with Fs. Enhanced Fs signals are found when the stratospheric quasi-biennial oscillation (QBO) is westerly. In the extrapolar region of the stratosphere, 0.1–0.6 and 0.1–0.7 K increases in Ta are associated with solar irradiance and with geomagnetic activity, respectively. In this region, Fs signals are strengthened when either the QBO is easterly, or geomagnetic activity is high, while Ap signals are strengthened when either the QBO is westerly, or solar irradiance is high. High solar irradiance and geomagnetic activity tend to enhance each other's signatures either making the signals stronger and symmetric about the equator or extending the signals to broader areas, or both. Positive Ap signals dominate the middle Arctic stratosphere and are two to five times larger than those of Fs. When solar irradiance is low, the signature of Ap in Ta is asymmetric about the equator, with positive signals in the Arctic stratosphere and negative signals at midlatitudes of the NH stratosphere. Weaker stratospheric QBO signals are associated with high Ap and Fs, suggesting possible disturbances on the QBO. The signals of Ap and Fs are distinct from the positive temperature anomalies resulting from volcanic eruptions

Radio Astronomy

Contains reports on seven research projects.M. I. T. Sloan Fund for Basic ResearchNational Science Foundation (Grant GP-8415)Joint Services Electronics Programs (U. S. Army, U. S. Navy, and U. S. Air Force) under Contract DA 28-043-AMC-02536(E)National Aeronautics and Space Administration (Grant NGL 22-009-016

Astrometry and geodesy with radio interferometry: experiments, models, results

Summarizes current status of radio interferometry at radio frequencies between Earth-based receivers, for astrometric and geodetic applications. Emphasizes theoretical models of VLBI observables that are required to extract results at the present accuracy levels of 1 cm and 1 nanoradian. Highlights the achievements of VLBI during the past two decades in reference frames, Earth orientation, atmospheric effects on microwave propagation, and relativity.Comment: 83 pages, 19 Postscript figures. To be published in Rev. Mod. Phys., Vol. 70, Oct. 199

Photoelectron Flux Build-Up in the Plasmasphere

Processes which confine photoelectrons to the plasmasphere (e.g., collisional backscattering from the thermosphere and magnetic trapping due to pitch angle redistribution through Coulomb collisions in the plasmasphere) tend to increase the steady state photoelectron flux in the plasmasphere above the amplitude level that would otherwise have been attained. Theoretical calculations are presented of steady state photoelectron fluxes in the plasmasphere, for specified atmospheric and ionospheric conditions. (Observational plasma line intensity data for these conditions exist and will be compared elsewhere.) General features of the angular distribution are presented and compared with observations. The transparency of the plasmasphere and the backscattering properties of the thermosphere are investigated. The buildup effect due to collisional backscatter alone is calculated, and the combined buildup effect of pitch angle diffusion and backscatter is estimated. It is found that the inclusion of these effects increases the steady state photoelectron flux amplitude in the plasmasphere by about 50% over the value obtained when the buildup effects are neglected. The calculated steady state photoelectron fluxes in the plasmasphere are in good agreement with the available observations