477 research outputs found

    DISRUPTING FACULTY SERVICE: USING TECHNOLOGY TO INCREASE ACADEMIC SERVICE PRODUCTIVITY

    Get PDF
    Scholarly attention regarding faculty involvement has primarily focused on faculty opinions of shared governance and faculty influence on institutional decision-making. There has been limited attention given to academic service productivity and the effectiveness of traditional approaches toward the accomplishment of faculty service requirements. This paper discusses disruptive technological change as a subset of disruptive innovation and proposes a technology-based framework for increasing service productivity while maintaining effort with regard to faculty service requirements in academic institutions. Specifically, a social networking tool is used to approach academic service projects with organic involvement and measured progress. It is suggested that such an approach may have positive implications toward increasing productivity in academic service. Further, additional benefits inherent in the tool make possible the leveraging of external networks for further productivity gains with no increase in resources while fostering a standardization of products across universities

    The blind men and the AML elephant:can we feel the progress?

    Get PDF
    The pharmacological therapy of non-promyelocytic acute myeloid leukemia (AML) has remained unchanged for over 40 years with an anthracycline–cytarabine combination forming the backbone of induction treatments. Nevertheless, the survival of younger patients has increased due to improved management of the toxicity of therapies including stem cell transplantation. Older patients and those with infirmity that precludes treatment-intensification have, however, not benefited from improvements in supportive care and continue to experience poor outcomes. An increased understanding of the genomic heterogeneity of AML raises the possibility of treatment-stratification to improve prognosis. Thus, efforts to identify agents with non-conventional anti-leukemic effects have paralleled those aiming to optimize leukemia cell-kill with conventional chemotherapy, resulting in a number of randomized controlled trials (RCT). In the last 18 months, RCTs investigating the effects of vosaroxin, azacitidine and gemtuzumab ozogamycin and daunorubicin dose have been reported with some studies indicating a statistically significant survival benefit with the investigational agent compared with standard therapy and potentially, a new era in AML therapeutics. Given the increasing costs of cancer care, a review of these studies, with particular attention to the magnitude of clinical benefit with the newer agents would be useful, especially for physicians treating patients in single-payer health systems

    Resonant enhancements of high-order harmonic generation

    Get PDF
    Solving the one-dimensional time-dependent Schr\"odinger equation for simple model potentials, we investigate resonance-enhanced high-order harmonic generation, with emphasis on the physical mechanism of the enhancement. By truncating a long-range potential, we investigate the significance of the long-range tail, the Rydberg series, and the existence of highly excited states for the enhancements in question. We conclude that the channel closings typical of a short-range or zero-range potential are capable of generating essentially the same effects.Comment: 7 pages revtex, 4 figures (ps files

    Enhancement of bichromatic high-harmonic generation with a high-frequency field

    Full text link
    Using a high-frequency field superposed to a linearly polarized bichromatic laser field composed by a wave with frequency ω\omega and a wave with frequency 2ω2\omega , we show it is possible to enhance the intensity of a group of high harmonics in orders of magnitude. These harmonics have frequencies about 30% higher than the monochromatic-cutoff frequency, and, within the three-step-model framework, correspond to a set of electron trajectories for which tunneling ionization is strongly suppressed. Particular features in the observed enhancement suggest that the high-frequency field provides an additional mechanism for the electron to reach the continuum. This interpretation is supported by a time-frequency analysis of the harmonic yield. The additional high frequency field permits the control of this group of harmonics leaving all other sets of harmonics practically unchanged, which is an advantage over schemes involving only bichromatic fields.Comment: 6 pages RevTex, 5 figures (ps files), Changes in text, figures, references and equations include

    A national study of the association between traffic-related air pollution and adverse pregnancy outcomes in Canada, 1999–2008

    Get PDF
    AbstractNumerous studies have examined the association of air pollution with preterm birth and birth weight outcomes. Traffic-related air pollution has also increasingly been identified as an important contributor to adverse health effects of air pollution. We employed a national nitrogen dioxide (NO2) exposure model to examine the association between NO2 and pregnancy outcomes in Canada between 1999 and 2008. National models for NO2 (and particulate matter of median aerodynamic diameter <2.5µm (PM2.5) as a covariate) were developed using ground-based monitoring data, estimates from remote-sensing, land use variables and, for NO2, deterministic gradients relative to road traffic sources. Generalized estimating equations were used to examine associations with preterm birth, term low birth weight (LBW), small for gestational age (SGA) and term birth weight, adjusting for covariates including infant sex, gestational age, maternal age and marital status, parity, urban/rural place of residence, maternal place of birth, season, year of birth and neighbourhood socioeconomic status and per cent visible minority. Associations were reduced considerably after adjustment for individual covariates and neighbourhood per cent visible minority, but remained significant for SGA (odds ratio 1.04, 95%CI 1.02–1.06 per 20ppb NO2) and term birth weight (16.2g reduction, 95% CI 13.6–18.8g per 20ppb NO2). Associations with NO2 were of greater magnitude in a sensitivity analysis using monthly monitoring data, and among births to mothers born in Canada, and in neighbourhoods with higher incomes and a lower proportion of visible minorities. In two pollutant models, associations with NO2 were less sensitive to adjustment for PM2.5 than vice versa, and there was consistent evidence of a dose-response relationship for NO2 but not PM2.5. In this study of approximately 2.5 million Canadian births between 1999 and 2008, we found significant associations of NO2 with SGA and term birth weight which remained significant after adjustment for PM2.5, suggesting that traffic may be a particularly important source with respect to the role of air pollution as a risk factor for adverse pregnancy outcomes

    The UK solar energy resource and the impact of climate change

    Get PDF
    AbstractSolar energy use in the UK is increasing dramatically, providing both heat energy and generation of electricity. This trend is expected to continue due to solar technologies becoming cheaper and more readily available along with low carbon government legislation such as the Renewable Heat Incentive (RHI) and Feed in Tariffs (FiTs) supporting solar energy deployment. However, the effects of climate change on the solar resource remain largely unstudied. Climate change affects cloud cover characteristics and consequently directly affects the performance of solar energy technologies.This paper investigates the UK solar irradiation resource for both the present and future climates.The present solar irradiation level was assessed through the conversion of 30 years of observed historical monthly average sunshine duration data. The method and results are validated by comparing the converted solar irradiation levels to actual solar irradiance measurements at weather stations with significant historical records of solar irradiance data.The impact of climate change is investigated across different regions of the UK by using the UKCP09 probabilistic climate change projections.We find that the current average UK annual solar resource is 101.2 Wm−2, ranging from 128.4 Wm−2 in the south of England to 71.8 Wm−2 in the northwest of Scotland. It seems likely that climate change will increase the average resource in the south of the UK, while marginally decreasing it in the Northwest. The overall effect is a mean increase of the UK solar resource, however it will have greater seasonal variability and discrepancies between geographical regions will be reinforced

    Entangled Stories: The Red Jews in Premodern Yiddish and German Apocalyptic Lore

    Get PDF
    “Far, far away from our areas, somewhere beyond the Mountains of Darkness, on the other side of the Sambatyon River…there lives a nation known as the Red Jews.” The Red Jews are best known from classic Yiddish writing, most notably from Mendele's Kitser masoes Binyomin hashlishi (The Brief Travels of Benjamin the Third). This novel, first published in 1878, represents the initial appearance of the Red Jews in modern Yiddish literature. This comical travelogue describes the adventures of Benjamin, who sets off in search of the legendary Red Jews. But who are these Red Jews or, in Yiddish, di royte yidelekh? The term denotes the Ten Lost Tribes of Israel, the ten tribes that in biblical times had composed the Northern Kingdom of Israel until they were exiled by the Assyrians in the eighth century BCE. Over time, the myth of their return emerged, and they were said to live in an uncharted location beyond the mysterious Sambatyon River, where they would remain until the Messiah's arrival at the end of time, when they would rejoin the rest of the Jewish people. This article is part of a broader study of the Red Jews in Jewish popular culture from the Middle Ages through modernity. It is partially based on a chapter from my book, Umstrittene Erlöser: Politik, Ideologie und jüdisch-christlicher Messianismus in Deutschland, 1500–1600 (Göttingen: Vandenhoeck & Ruprecht, 2011). Several postdoctoral fellowships have generously supported my research on the Red Jews: a Dr. Meyer-Struckmann-Fellowship of the German Academic Foundation, a Harry Starr Fellowship in Judaica/Alan M. Stroock Fellowship for Advanced Research in Judaica at Harvard University, a research fellowship from the Heinrich Hertz-Foundation, and a YIVO Dina Abramowicz Emerging Scholar Fellowship. I thank the organizers of and participants in the colloquia and conferences where I have presented this material in various forms as well as the editors and anonymous reviewers of AJS Review for their valuable comments and suggestions. I am especially grateful to Jeremy Dauber and Elisheva Carlebach of the Institute for Israel and Jewish Studies at Columbia University, where I was a Visiting Scholar in the fall of 2009, for their generous encouragement to write this article. Sue Oren considerably improved my English. The style employed for Romanization of Yiddish follows YIVO's transliteration standards. Unless otherwise noted, translations from the Yiddish, Hebrew, German, and Latin are my own. Quotations from the Bible follow the JPS translation, and those from the Babylonian Talmud are according to the Hebrew-English edition of the Soncino Talmud by Isidore Epstein

    Gender ‘hostility’, rape, and the hate crime paradigm

    Get PDF
    This article examines whether crimes motivated by, or which demonstrate, gender ‘hostility’ should be included within the current framework of hate crime legislation in England and Wales. The article uses the example of rape to explore the parallels (both conceptual and evidential) between gender‐motivated violence and other ‘archetypal’ forms of hate crime. It is asserted that where there is clear evidence of gender hostility during the commission of an offence, a defendant should be pursued in law additionally as a hate crime offender. In particular it is argued that by focusing on the hate‐motivation of many sexual violence offenders, the criminal justice system can begin to move away from its current focus on the ‘sexual’ motivations of offenders and begin to more effectively challenge the gendered prejudices that are frequently causal to such crimes

    Evolution of form in metal-organic frameworks

    Get PDF
    Self-assembly has proven to be a widely successful synthetic strategy for functional materials, especially for metal-organic materials (MOMs), an emerging class of porous materials consisting of metal-organic frameworks (MOFs) and metal-organic polyhedra (MOPs). However, there are areas in MOM synthesis in which such self-assembly has not been fully utilized, such as controlling the interior of MOM crystals. Here we demonstrate sequential self-assembly strategy for synthesizing various forms of MOM crystals, including double-shell hollow MOMs, based on single-crystal to single-crystal transformation from MOP to MOF. Moreover, this synthetic strategy also yields other forms, such as solid, core-shell, double and triple matryoshka, and single-shell hollow MOMs, thereby exhibiting form evolution in MOMs. We anticipate that this synthetic approach might open up a new direction for the development of diverse forms in MOMs, with highly advanced areas such as sequential drug delivery/release and heterogeneous cascade catalysis targeted in the foreseeable future.ope
    corecore