739 research outputs found
Enhanced mapping of artificially modified ground in urban areas : using borehole, map and remotely sensed data
The report described here is focused on how using boreholes and attributes from boreholes
increased and enhanced the mapping of Artificially Modified Ground, and helped measure
landscape evolution change in the urban environment. These attributes from boreholes include
the presence of AMG in a borehole, the thickness of AMG recorded, the start height of a
borehole and the location of boreholes (and other boreholes in close proximity) with modern
topological features and geological maps
The London Basin superficial and bedrock LithoFrame 50 Model
This report describes the methodology and datasets used in the construction of the 1:50 000
resolution superficial and bedrock geological model of the London Basin.
The London Basin study area was divided into twelve 20 x 20 km tiles, with construction of the
first tiles beginning in 2006 and completion of the combined model in 2014. This time period
coincided with the ongoing development of GSI3D software which was used to construct much
of the model. The GSI3D software was used to calculate a rockhead (base Quaternary and
Anthropocene) surface that was then used as a capping surface for the modelling of the bedrock
geology in the GOCAD® software.
The model complements the corresponding DiGMapGB-50 tiles of the area and consists of about
80 modelled geological units, comprising mass movement (landslip), artificial, superficial, and
bedrock.
This report supersedes an earlier report detailing the construction of the superficial part of this
model (Burke et al. 2013).
A glossary of technical terms used is included at the end of this report
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PROTEOLYTIC REMOVAL OF THE CARBOXYL TERMINUS OF THE T4 GENE 32 HELIX-DESTABILIZING PROTEIN ALTERS THE T4 IN VITRO REPLICATION COMPLEX
The proteolytic removal of about 60 amino acids from the COOH terminus of the bacteriophage T4 helix-destabilizing protein (gene 32 protein) produces 32*I, a 27,000-dalton fragment which still binds tightly and cooperatively to single-stranded DNA. The substitution of 32*I protein for intact 32 protein in the seven-protein T4 replication complex results in dramatic changes in some of the reactions catalyzed by this in vitro DNA replication system, while leaving others largely unperturbed. (1) Like intact 32 protein, the 32*I protein promotes DNA synthesis by the DNA polymerase when the T4 polymerase accessory proteins (gene 44/62 and 45 proteins) are also present. The host helix-destabilizing protein (Escherichia coli ssb protein) cannot replace the 32*I protein for this synthesis. (2) Unlike intact 32 protein, 32*I protein strongly inhibits DNA synthesis catalyzed by the T4 DNA polymerase alone on a primed single-stranded DNA template. (3) Unlike intact 32 protein, the 32*I protein strongly inhibits RNA primer synthesis catalyzed by the T4 gene 41 and 61 proteins and also reduces the efficiency of RNA primer utilization. As a result, de novo DNA chain starts are blocked completely in the complete T4 replication system, and no lagging strand DNA synthesis occurs. (4) The 32*I protein does not bind to either the T4 DNA polymerase or to the T4 gene 61 protein in the absence of DNA; these associations (detected with intact 32 protein) would therefore appear to be essential for the normal control of 32 protein activity, and to account at least in part for observations 2 and 3, above. We propose that the COOH-terminal domain of intact 32 protein functions to guide its interactions with the T4 DNA polymerase and the T4 gene 61 RNA-priming protein. When this domain is removed, as in 32*I protein, the helix destabilization induced by the protein is controlled inadequately, so that polymerizing enzymes tend to be displaced from the growing 3{prime}-OH end of a polynucleotide chain and are thereby inhibited. Eukaryotic helix-destabilizing proteins may also have similar functional domains essential for the control of their activities
A geological model of London and the Thames Valley, southeast England
Many geological survey organisations have started delivering digital geological models as part of their role. This article describes the British Geological Survey (BGS) model for London and the Thames Valley in southeast England. The model covers 4800 km2 and extends to several hundred metres depth. It includes extensive spreads of Quaternary river terraces and alluvium of the Thames drainage system resting on faulted and folded Palaeogene and Cretaceous bedrock strata. The model extends to the base of the Jurassic sedimentary rocks.
The baseline datasets used and the uses and limitations of the model are given. The model has been used to generate grids for the elevation of the base of the Quaternary, the thickness of Quaternary deposits, and enabled a reassessment of the subcrop distribution and faulting of the Palaeogene and Cretaceous bedrock units especially beneath the Quaternary deposits.
Digital outputs from the model include representations of geological surfaces, which can be used in GIS, CAD and geological modelling software, and also graphic depictions such as a fence diagram of cross-sections through the model. The model can be viewed as a whole, and be dissected, in the BGS Lithoframe Viewer. Spatial queries of this and other BGS models, at specific points, along defined lines or at a specified depth, can be performed with the new BGS Groundhog application, which delivers template-based reports.
The model should be viewed as a first version that should be improved further, and kept up to date, as new data and understanding emerges
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Heavy ion fusion program at Argonne
Argonne's Heavy Ion Fusion (HIF) program is trying for two major achievements during the coming 4 to 5 years. The primary objective is to demonstrate accelerator operation in areas that are especially important for the use of heavy ion accelerator systems as drivers in inertial fusion power plants. These demonstrations comprise reliable operation of a front end (source, preaccelerator, and rf linac to approx. 10 MeV) with adequate output beam current and emittance; tolerable emittance growth during further acceleration in an rf linac (including frequency transition, with simulated linac-beam combination, and intense beam stripping); strong debunching; multiturn injection with minimal beam loss and tolerable phase space dilution; beam compression; and efficient focusing. The second objective is to demonstrate efficient stopping of intense ion beams in material at conditions relevant to fusion pellet implosion. For this purpose, the apparatus of the primary (accelerator) demonstration would be modified to include a synchrotron accelerating the 220 MeV Xe/sup +8/ from the linac to 10 GeV
Non-Equilibrium Statistical Physics of Currents in Queuing Networks
We consider a stable open queuing network as a steady non-equilibrium system
of interacting particles. The network is completely specified by its underlying
graphical structure, type of interaction at each node, and the Markovian
transition rates between nodes. For such systems, we ask the question ``What is
the most likely way for large currents to accumulate over time in a network
?'', where time is large compared to the system correlation time scale. We
identify two interesting regimes. In the first regime, in which the
accumulation of currents over time exceeds the expected value by a small to
moderate amount (moderate large deviation), we find that the large-deviation
distribution of currents is universal (independent of the interaction details),
and there is no long-time and averaged over time accumulation of particles
(condensation) at any nodes. In the second regime, in which the accumulation of
currents over time exceeds the expected value by a large amount (severe large
deviation), we find that the large-deviation current distribution is sensitive
to interaction details, and there is a long-time accumulation of particles
(condensation) at some nodes. The transition between the two regimes can be
described as a dynamical second order phase transition. We illustrate these
ideas using the simple, yet non-trivial, example of a single node with
feedback.Comment: 26 pages, 5 figure
Global Search for New Physics with 2.0/fb at CDF
Data collected in Run II of the Fermilab Tevatron are searched for
indications of new electroweak-scale physics. Rather than focusing on
particular new physics scenarios, CDF data are analyzed for discrepancies with
the standard model prediction. A model-independent approach (Vista) considers
gross features of the data, and is sensitive to new large cross-section
physics. Further sensitivity to new physics is provided by two additional
algorithms: a Bump Hunter searches invariant mass distributions for "bumps"
that could indicate resonant production of new particles; and the Sleuth
procedure scans for data excesses at large summed transverse momentum. This
combined global search for new physics in 2.0/fb of ppbar collisions at
sqrt(s)=1.96 TeV reveals no indication of physics beyond the standard model.Comment: 8 pages, 7 figures. Final version which appeared in Physical Review D
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