949 research outputs found
DESIGN AND DEVELOPMENT OF AN ONLINE DATABASE SYSTEM FOR INVENTORY STOCK MANAGEMENT
Inventory management is an important aspect where it is a system to control its stocks or product. This aspect will determine the flow of the business profit or loss within a company. The objective of this project is to investigate and select appropriate programming software for the development, design, and develop the system and assess the level of satisfaction of the system. This project uses the Hypertext Markup Language (HTML), Hypertext Pre-processor or Personal Home Pages (PHP), Structured Query Language (MySQL), and Visual Studio
Code software as the programming language and development platform of the system. The method being implemented into this project is the Agile Development method containing
planning, design, development, testing, and evaluation. This project's function is to ease shopkeepers and also their customer. It works by updating their products stock into the system rather than manually update by using paper and pen. Customers can shop items from their
homes by using this system’s ordering feature. Then the evaluation being deployed is using the usability evaluation to few selected respondents. The results highlight that all of the evaluators are satisfied and can use the system easily and our evaluation shows that the function works according to the planned features. In the conclusion, the design and development of an online database system for inventory stock management were successfully developed and can be used by users to ease their daily work and activities. The three
objectives in this project were me
Determination of the combined vibrational and acoustic emission signature of a wind turbine gearbox and generator shaft in service as a pre-requisite for effective condition monitoring
This is the post-print version of the final paper published in Renewable Energy. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. Copyright @ 2013 Elsevier B.V.A review of current progress in Condition Monitoring (CM) of wind turbine gearboxes and generators is presented, as an input to the design of a new continuous CM system with automated warnings based on a combination of vibrational and Acoustic Emission (AE) analysis. For wind turbines, existing reportage on vibrational monitoring is restricted to a few case histories whilst data on AE is even scarcer. In contrast, this paper presents combined vibration and AE monitoring performed over a continuous period of 5 days on a wind turbine. The vibrational and AE signatures for a healthy wind turbine gearbox and generator were obtained as a function of wind speed and turbine power, for the full normal range of these operational variables. i.e. 5–25 m/s and 0–300 kW respectively. The signatures have been determined as a vital pre-requisite for the identification of abnormal signatures attributable to shaft and gearbox defects. Worst-case standard deviations have been calculated for the sensor data. These standard deviations determine the minimum defect signal that could be detected within the defined time interval without false alarms in an automated warning system.UK Northern Wind Innovation Program NWI
Capsule Size Alters the Timing of Metabolic Alkalosis Following Sodium Bicarbonate Supplementation
Localisation and interactions of the Vipp1 protein in cyanobacteria
Biotechnology and Biological Sciences Research Council. Grant Number: BB/G021856. Deutsche Forschungsgemeinschaft. Grant Number: FOR 929, SCHN 690/3-1. European Commission. Grant Number: FP7-PEOPLE-2009-IEF 254575. NFR. Grant Numbers: 192436, 197119. OCISB. Royal Society and Engineering and Physical Sciences Research Council. Grant Number: EP/G0061009/
Destabilization of the thermohaline circulation by transient perturbations to the hydrological cycle
We reconsider the problem of the stability of the thermohaline circulation as
described by a two-dimensional Boussinesq model with mixed boundary conditions.
We determine how the stability properties of the system depend on the intensity
of the hydrological cycle. We define a two-dimensional parameters' space
descriptive of the hydrology of the system and determine, by considering
suitable quasi-static perturbations, a bounded region where multiple equilibria
of the system are realized. We then focus on how the response of the system to
finite-amplitude surface freshwater forcings depends on their rate of increase.
We show that it is possible to define a robust separation between slow and fast
regimes of forcing. Such separation is obtained by singling out an estimate of
the critical growth rate for the anomalous forcing, which can be related to the
characteristic advective time scale of the system.Comment: 37 pages, 8 figures, submitted to Clim. Dy
The Thermal Design, Characterization, and Performance of the SPIDER Long-Duration Balloon Cryostat
We describe the SPIDER flight cryostat, which is designed to cool six
millimeter-wavelength telescopes during an Antarctic long-duration balloon
flight. The cryostat, one of the largest to have flown on a stratospheric
payload, uses liquid helium-4 to deliver cooling power to stages at 4.2 and 1.6
K. Stainless steel capillaries facilitate a high flow impedance connection
between the main liquid helium tank and a smaller superfluid tank, allowing the
latter to operate at 1.6 K as long as there is liquid in the 4.2 K main tank.
Each telescope houses a closed cycle helium-3 adsorption refrigerator that
further cools the focal planes down to 300 mK. Liquid helium vapor from the
main tank is routed through heat exchangers that cool radiation shields,
providing negative thermal feedback. The system performed successfully during a
17 day flight in the 2014-2015 Antarctic summer. The cryostat had a total hold
time of 16.8 days, with 15.9 days occurring during flight.Comment: 15 pgs, 17 fig
Serial bone marrow transplantation reveals in vivo expression of the pCLPG retroviral vector
<p>Abstract</p> <p>Background</p> <p>Gene therapy in the hematopoietic system remains promising, though certain aspects of vector design, such as transcriptional control elements, continue to be studied. Our group has developed a retroviral vector where transgene expression is controlled by p53 with the intention of harnessing the dynamic and inducible nature of this tumor suppressor and transcription factor. We present here a test of <it>in vivo </it>expression provided by the p53-responsive vector, pCLPG. For this, we used a model of serial transplantation of transduced bone marrow cells.</p> <p>Results</p> <p>We observed, by flow cytometry, that the eGFP transgene was expressed at higher levels when the pCLPG vector was used as compared to the parental pCL retrovirus, where expression is directed by the native MoMLV LTR. Expression from the pCLPG vector was longer lasting, but did decay along with each sequential transplant. The detection of eGFP-positive cells containing either vector was successful only in the bone marrow compartment and was not observed in peripheral blood, spleen or thymus.</p> <p>Conclusions</p> <p>These findings indicate that the p53-responsive pCLPG retrovirus did offer expression <it>in vivo </it>and at a level that surpassed the non-modified, parental pCL vector. Our results indicate that the pCLPG platform may provide some advantages when applied in the hematopoietic system.</p
Using Fluorescence Recovery After Photobleaching (FRAP) to study dynamics of the Structural Maintenance of Chromosome (SMC) complex in vivo
The SMC complex, MukBEF, is important for chromosome organization and
segregation in Escherichia coli. Fluorescently tagged MukBEF forms distinct
spots (or 'foci') in the cell, where it is thought to carry out most of its
chromosome associated activities. This chapter outlines the technique of
Fluorescence Recovery After Photobleaching (FRAP) as a method to study the
properties of YFP-tagged MukB in fluorescent foci. This method can provide
important insight into the dynamics of MukB on DNA and be used to study its
biochemical properties in vivo
Improving Human Plateaued Motor Skill with Somatic Stimulation
Procedural motor learning includes a period when no substantial gain in performance improvement is obtained even with repeated, daily practice. Prompted by the potential benefit of high-frequency transcutaneous electrical stimulation, we examined if the stimulation to the hand reduces redundant motor activity that likely exists in an acquired hand motor skill, so as to further upgrade stable motor performance. Healthy participants were trained until their motor performance of continuously rotating two balls in the palm of their right hand became stable. In the series of experiments, they repeated a trial performing this cyclic rotation as many times as possible in 15 s. In trials where we applied the stimulation to the relaxed thumb before they initiated the task, most reported that their movements became smoother and they could perform the movements at a higher cycle compared to the control trials. This was not possible when the dorsal side of the wrist was stimulated. The performance improvement was associated with reduction of amplitude of finger displacement, which was consistently observed irrespective of the task demands. Importantly, this kinematic change occurred without being noticed by the participants, and their intentional changes of motor strategies (reducing amplitude of finger displacement) never improved the performance. Moreover, the performance never spontaneously improved during one-week training without stimulation, whereas the improvement in association with stimulation was consistently observed across days during training on another week combined with the stimulation. The improved effect obtained in stimulation trials on one day partially carried over to the next day, thereby promoting daily improvement of plateaued performance, which could not be unlocked by the first-week intensive training. This study demonstrated the possibility of effectively improving a plateaued motor skill, and pre-movement somatic stimulation driving this behavioral change
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