100 research outputs found
Quinductor: a multilingual data-driven method for generating reading-comprehension questions using Universal Dependencies
We propose a multilingual data-driven method for generating reading
comprehension questions using dependency trees. Our method provides a strong,
mostly deterministic, and inexpensive-to-train baseline for less-resourced
languages. While a language-specific corpus is still required, its size is
nowhere near those required by modern neural question generation (QG)
architectures. Our method surpasses QG baselines previously reported in the
literature and shows a good performance in terms of human evaluation
Interaction strategies for an affective conversational agent
The development of embodied conversational agents (ECA) as companions brings several challenges for both affective and conversational dialogue. These include challenges in generating appropriate affective responses, selecting the overall shape of the dialogue, providing prompt system response times, and handling interruptions. We present an implementation of such a companion showing the development of individual modules that attempt to address these challenges. Further, to resolve resulting conflicts, we present encompassing interaction strategies that attempt to balance the competing requirements along with dialogues from our working prototype to illustrate these interaction strategies in operation. Finally, we provide the results of an evaluation of the companion using an evaluation methodology created for conversational dialogue and including analysis using appropriateness annotation
Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial
Background:
Glucagon-like peptide 1 receptor agonists differ in chemical structure, duration of action, and in their effects on clinical outcomes. The cardiovascular effects of once-weekly albiglutide in type 2 diabetes are unknown. We aimed to determine the safety and efficacy of albiglutide in preventing cardiovascular death, myocardial infarction, or stroke.
Methods:
We did a double-blind, randomised, placebo-controlled trial in 610 sites across 28 countries. We randomly assigned patients aged 40 years and older with type 2 diabetes and cardiovascular disease (at a 1:1 ratio) to groups that either received a subcutaneous injection of albiglutide (30–50 mg, based on glycaemic response and tolerability) or of a matched volume of placebo once a week, in addition to their standard care. Investigators used an interactive voice or web response system to obtain treatment assignment, and patients and all study investigators were masked to their treatment allocation. We hypothesised that albiglutide would be non-inferior to placebo for the primary outcome of the first occurrence of cardiovascular death, myocardial infarction, or stroke, which was assessed in the intention-to-treat population. If non-inferiority was confirmed by an upper limit of the 95% CI for a hazard ratio of less than 1·30, closed testing for superiority was prespecified. This study is registered with ClinicalTrials.gov, number NCT02465515.
Findings:
Patients were screened between July 1, 2015, and Nov 24, 2016. 10 793 patients were screened and 9463 participants were enrolled and randomly assigned to groups: 4731 patients were assigned to receive albiglutide and 4732 patients to receive placebo. On Nov 8, 2017, it was determined that 611 primary endpoints and a median follow-up of at least 1·5 years had accrued, and participants returned for a final visit and discontinuation from study treatment; the last patient visit was on March 12, 2018. These 9463 patients, the intention-to-treat population, were evaluated for a median duration of 1·6 years and were assessed for the primary outcome. The primary composite outcome occurred in 338 (7%) of 4731 patients at an incidence rate of 4·6 events per 100 person-years in the albiglutide group and in 428 (9%) of 4732 patients at an incidence rate of 5·9 events per 100 person-years in the placebo group (hazard ratio 0·78, 95% CI 0·68–0·90), which indicated that albiglutide was superior to placebo (p<0·0001 for non-inferiority; p=0·0006 for superiority). The incidence of acute pancreatitis (ten patients in the albiglutide group and seven patients in the placebo group), pancreatic cancer (six patients in the albiglutide group and five patients in the placebo group), medullary thyroid carcinoma (zero patients in both groups), and other serious adverse events did not differ between the two groups. There were three (<1%) deaths in the placebo group that were assessed by investigators, who were masked to study drug assignment, to be treatment-related and two (<1%) deaths in the albiglutide group.
Interpretation:
In patients with type 2 diabetes and cardiovascular disease, albiglutide was superior to placebo with respect to major adverse cardiovascular events. Evidence-based glucagon-like peptide 1 receptor agonists should therefore be considered as part of a comprehensive strategy to reduce the risk of cardiovascular events in patients with type 2 diabetes.
Funding:
GlaxoSmithKline
Avoiding Dynamic Delays in Functional Logic Programs
. In several functional logic programming languages, functional expressions must be evaluated before unification with another term, but this can only be done if the functional expression is ground. If the functional expression is non-ground, then unification must be delayed until all the arguments have become instantiated to ground terms. If the delaying mechanism uses dynamic tests, the program will be unnecessarily inefficient. We present an analysis method for statically determining at what point in the program a given functional expression can be evaluated. This analysis is then used for transforming a functional logic program into an equivalent program, in which most dynamic delays are avoided. We show that this transformation can lead to considerable improvements in performance, compared to a dynamic delaying strategy. 1 Introduction During the last decade, an immense amount of research has been done on combining logic programming with functional and equational languages. The d..
S-SLD-resolution - An Operational Semantics for Logic Programs with External Procedures
This paper presents a new operational semantics for logic programs with external procedures, introduced in [BM88]. A new resolution procedure S-SLD-resolution is defined, in which each step of computation is characterized by a goal and a set of equational constraints, whose satisfiability cannot be decided with the information at hand. This approach improves the completeness of the resulting system, since further computation may result in the information needed to solve some earlier unsolved constraints. We also state a sufficient condition to distinguish a class of programs where no unsolved constraints will remain at the end of computation. 1 Introduction We will address the problem of defining an operational semantics for logic programs with external procedures, a formalism presented in [BM88, Bon89]. In this approach the external procedures, which can be written in any language, are regarded as "black boxes" that reduce ground terms. Under this assumption an external procedure imp..
UDon2: a library for manipulating Universal Dependencies trees
UDon2 is an open-source library for manipulating dependency trees represented in the CoNLL-U format. The library is compatible with the Universal Dependencies. UDon2 is aimed at developers of downstream Natural Language Processing applications that require manipulating dependency trees on the sentence level (in addition to other available tools geared towards working with treebanks).QC 20210115</p
Quasi : a synthetic Question-Answering dataset in Swedish using GPT-3 and zero-shot learning
This paper describes the creation and evaluation of a synthetic dataset of Swedish multiple-choice questions (MCQs) for reading comprehension using GPT-3. Although GPT-3 is trained mostly on English data, with only 0.11% of Swedish texts in its training material, the model still managed to generate MCQs in Swedish. About 44% of the generated MCQs turned out to be of sufficient quality, i.e.\ they were grammatically correct and relevant, with exactly one answer alternative being correct and the others being plausible but wrong. We provide a detailed analysis of the errors and shortcomings of the rejected MCQs, as well an analysis of the level of difficulty of the accepted MCQs. In addition to giving insights into GPT-3, the synthetic dataset could be used for training and evaluation of special-purpose MCQ-generating models.QC 20230602</p
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