406 research outputs found
A GBT Survey for HI 21 cm Absorption in the Disks and Halos of Low-Redshift Galaxies
We present an HI 21 cm absorption survey with the Green Bank Telescope (GBT)
of galaxy-quasar pairs selected by combining data from the Sloan Digital Sky
Survey (SDSS) and the Faint Images of the Radio Sky at Twenty-Centimeters
(FIRST) survey. Our sample consists of 23 sightlines through 15 low-redshift
foreground galaxy - background quasar pairs with impact parameters ranging from
1.7 kpc up to 86.7 kpc. We detected one absorber in the GBT survey from the
foreground dwarf galaxy, GQ1042+0747, at an impact parameter of 1.7 kpc and
another possible absorber in our follow-up Very Large Array (VLA) imaging of
the nearby foreground galaxy, UGC 7408. Both of the absorbers are narrow (FWHM
of 3.6 and 4.8 km/s), have sub Damped Lyman alpha column densities, and most
likely originate in the disk gas of the foreground galaxies. We also detected H
I emission from three foreground galaxies, including UGC 7408. Although our
sample contains both blue and red galaxies, the two H I absorbers as well as
the H I emissions are associated with blue galaxies. We discuss the physical
conditions in the 21 cm absorbers and some drawbacks of the large GBT beam for
this type of survey.Comment: 15 pages, 6 figures, 3 table
Magellan LDSS3 emission confirmation of galaxies hosting metal-rich Lyman-alpha absorption systems
Using the Low Dispersion Survey Spectrograph 3 at the Magellan II Clay
Telescope, we target {candidate absorption host galaxies} detected in deep
optical imaging {(reaching limiting apparent magnitudes of 23.0-26.5 in and filters) in the fields of three QSOs, each of which shows the
presence of high metallicity, high absorption systems in their
spectra (Q0826-2230: =0.9110, Q1323-0021: ,
Q1436-0051: ). We confirm three host galaxies {at
redshifts 0.7387, 0.7401, and 0.9286} for two of the Lyman- absorption
systems (one with two galaxies interacting). For these systems, we are able to
determine the star formation rates (SFRs); impact parameters (from previous
imaging detections); the velocity shift between the absorption and emission
redshifts; and, for one system, also the emission metallicity.} Based on
previous photometry, we find these galaxies have LL. The [O II]
SFRs for these galaxies are in the range M yr
{(uncorrected for dust)}, while the impact parameters lie in the range
kpc. {Despite the fact that we have confirmed galaxies at 50 kpc from the QSO,
no gradient in metallicity is indicated between the absorption metallicity
along the QSO line of sight and the emission line metallicity in the galaxies.}
We confirm the anti-correlation between impact parameter and from
the literature. We also report the emission redshift of five other galaxies:
three at , and two (LL) at not
corresponding to any known absorption systems.Comment: 14 pages, 7 figures, 4 tables, accepted to MNRA
Low and High Ionization Absorption Properties of Mg II Absorption-Selected Galaxies at Intermediate Redshifts. I. General Properties
We present extensive metal-line absorption properties for 45 absorption
systems that were selected by their Mg II absorption at redshifts between 0.4
and 1.4. For each system the properties of several chemical species are
determined, including a wide range of ionization conditions. In the optical,
the absorption systems have been observed at ~6 km/s resolution with
HIRES/Keck, which covered Mg II, several Fe II transitions, Mg I, and in some
cases (depending upon redshift), Ca II, Ti II, Mn II, and Al III. Ultraviolet,
lower resolution (~230 km/s) Faint Object Spectrograph data (1600 - 3275 Ang)
were obtained from the Hubble Space Telescope archive. These spectra covered Al
II, Al III, Si II, Si III, Si IV, C II, C III, C IV, N V, O VI, and several
Lyman series transitions, with coverage dependent upon the absorption system
redshift. From these data, we infer that Mg II absorbing galaxies at
intermediate redshifts have multiphase gaseous structures.Comment: Accepted: The Astrophysical Journa
An Analysis of Private School Closings
We add to the small literature on private school supply by exploring exits of K-12 private schools. We find that the closure of private schools is not an infrequent event, and use national survey data from the National Center for Education Statistics to study closures of private schools. We assume that the probability of an exit is a function of excess supply of private schools over the demand, as well as the school's characteristics such as age, size, and religious affiliation. Our empirical results generally support the implications of the model. Working Paper 07-0
Photometric redshifts and quasar probabilities from a single, data-driven generative model
We describe a technique for simultaneously classifying and estimating the
redshift of quasars. It can separate quasars from stars in arbitrary redshift
ranges, estimate full posterior distribution functions for the redshift, and
naturally incorporate flux uncertainties, missing data, and multi-wavelength
photometry. We build models of quasars in flux-redshift space by applying the
extreme deconvolution technique to estimate the underlying density. By
integrating this density over redshift one can obtain quasar flux-densities in
different redshift ranges. This approach allows for efficient, consistent, and
fast classification and photometric redshift estimation. This is achieved by
combining the speed obtained by choosing simple analytical forms as the basis
of our density model with the flexibility of non-parametric models through the
use of many simple components with many parameters. We show that this technique
is competitive with the best photometric quasar classification
techniques---which are limited to fixed, broad redshift ranges and high
signal-to-noise ratio data---and with the best photometric redshift techniques
when applied to broadband optical data. We demonstrate that the inclusion of UV
and NIR data significantly improves photometric quasar--star separation and
essentially resolves all of the redshift degeneracies for quasars inherent to
the ugriz filter system, even when included data have a low signal-to-noise
ratio. For quasars spectroscopically confirmed by the SDSS 84 and 97 percent of
the objects with GALEX UV and UKIDSS NIR data have photometric redshifts within
0.1 and 0.3, respectively, of the spectroscopic redshift; this amounts to about
a factor of three improvement over ugriz-only photometric redshifts. Our code
to calculate quasar probabilities and redshift probability distributions is
publicly available
The Sloan Digital Sky Survey Quasar Lens Search. IV. Statistical Lens Sample from the Fifth Data Release
We present the second report of our systematic search for strongly lensed
quasars from the data of the Sloan Digital Sky Survey (SDSS). From extensive
follow-up observations of 136 candidate objects, we find 36 lenses in the full
sample of 77,429 spectroscopically confirmed quasars in the SDSS Data Release
5. We then define a complete sample of 19 lenses, including 11 from our
previous search in the SDSS Data Release 3, from the sample of 36,287 quasars
with i<19.1 in the redshift range 0.6<z<2.2, where we require the lenses to
have image separations of 1"<\theta<20" and i-band magnitude differences
between the two images smaller than 1.25 mag. Among the 19 lensed quasars, 3
have quadruple-image configurations, while the remaining 16 show double images.
This lens sample constrains the cosmological constant to be
\Omega_\Lambda=0.84^{+0.06}_{-0.08}(stat.)^{+0.09}_{-0.07}(syst.) assuming a
flat universe, which is in good agreement with other cosmological observations.
We also report the discoveries of 7 binary quasars with separations ranging
from 1.1" to 16.6", which are identified in the course of our lens survey. This
study concludes the construction of our statistical lens sample in the full
SDSS-I data set.Comment: 37 pages, 2 figures and 5 tables, accepted to A
Using 21cm Absorption in Small Impact Parameter Galaxy-QSO Pairs to Probe Low-Redshift Damped and Sub-Damped Lyman-alpha System
To search for low-redshift damped Lyman-alpha (DLA) and sub-DLA quasar
absorbers, we have conducted a 21cm absorption survey of radio-loud quasars at
small impact parameters to foreground galaxies selected from the Sloan Digital
Sky Survey (SDSS). Here we present the first results from this survey based on
observations of SDSS J104257.58+074850.5 ( = 2.66521), a quasar at an
angular separation from a foreground galaxy ( = 0.03321) of 2.5" (1.7
kpc in projection). The foreground galaxy is a low-luminosity spiral with
on-going star formation (0.004 M yr kpc) and a
metallicity of dex. We detect 21cm absorption from the galaxy
with the Green Bank Telescope (GBT), the Very Large Array (VLA), and the Very
Long Baseline Array (VLBA). The absorption appears to be quiescent disk gas
corotating with the galaxy and we do not find any evidence for outflowing cold
neutral gas. The width of the main absorption line indicates that the gas is
cold, K, and the HI column is surprisingly low given the impact
parameter of 1.7 kpc; we find that N(HI) cm
(GBT) and N(HI) cm (VLBA). VLBA marginally
resolves the continuum source and the absorber, and a lower limit of 27.1
13.9 pc is derived for the size of the absorbing cloud. In turn, this
indicates a low density for a cold cloud, n(HI) 3.5 cm. We
hypothesize that this galaxy, which is relatively isolated, is becoming
depleted in HI because it is converting its interstellar matter into stars
without a replenishing source of gas, and we suggest future observations to
probe this and similar galaxies.Comment: 16 Pages including 12 Figures and 2 Table
The Far Ultraviolet Spectroscopic Explorer Survey of OVI Absorption in the Disk of the Milky Way
To probe the distribution and physical characteristics of interstellar gas at
temperatures T ~ 3e5 K in the disk of the Milky Way, we have used the Far
Ultraviolet Spectroscopic Explorer (FUSE) to observe absorption lines of OVI
toward 148 early-type stars situated at distances 1 kpc. After subtracting off
a mild excess of OVI arising from the Local Bubble, combining our new results
with earlier surveys of OVI, and eliminating stars that show conspicuous
localized X-ray emission, we find an average OVI mid-plane density n_0 = 1.3e-8
cm^-3. The density decreases away from the plane of the Galaxy in a way that is
consistent with an exponential scale height of 3.2 kpc at negative latitudes or
4.6 kpc at positive latitudes. Average volume densities of OVI along different
sight lines exhibit a dispersion of about 0.26 dex, irrespective of the
distances to the target stars. This indicates that OVI does not arise in
randomly situated clouds of a fixed size and density, but instead is
distributed in regions that have a very broad range of column densities, with
the more strongly absorbing clouds having a lower space density. Line widths
and centroid velocities are much larger than those expected from differential
Galactic rotation, but they are nevertheless correlated with distance and
N(OVI), which reinforces our picture of a diverse population of hot plasma
regions that are ubiquitous over the entire Galactic disk. The velocity
extremes of the OVI profiles show a loose correlation with those of very strong
lines of less ionized species, supporting a picture of a turbulent, multiphase
medium churned by shock-heated gas from multiple supernova explosions.Comment: Accepted for publication in ApJS. Preprint with full resolution
images and all 148 spectra available at
http://www.astro.princeton.edu/~dvb/o
A Schistosome cAMP-Dependent Protein Kinase Catalytic Subunit Is Essential for Parasite Viability
Eukaryotes, protozoan, and helminth parasites make extensive use of protein kinases to control cellular functions, suggesting that protein kinases may represent novel targets for the development of anti-parasitic drugs. Because of their central role in intracellular signaling pathways, cyclic nucleotide–dependent kinases such as cAMP-dependent protein kinase (PKA) represent promising new targets for the treatment of parasitic infections and neoplastic disorders. However, the role of these kinases in schistosome biology has not been characterized and the genes encoding schistosome PKAs have not been identified. Here we provide biochemical evidence for the presence of a PKA signaling pathway in adult Schistosoma mansoni and show that PKA activity is required for parasite viability in vitro. We also provide the first full description of a gene that encodes a PKA catalytic subunit in S. mansoni, named SmPKA-C. Finally we demonstrate, through RNA interference, that SmPKA-C contributes to the PKA activity we detected biochemically and that inhibition of SmPKA-C expression in adult schistosomes results in parasite death. Together our data show that SmPKA-C is a critically important gene product and may represent an attractive therapeutic target for the treatment and control of schistosomiasis
Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas
Although theMYConcogene has been implicated incancer, a systematic assessment of alterations ofMYC, related transcription factors, and co-regulatoryproteins, forming the proximal MYC network (PMN),across human cancers is lacking. Using computa-tional approaches, we define genomic and proteo-mic features associated with MYC and the PMNacross the 33 cancers of The Cancer Genome Atlas.Pan-cancer, 28% of all samples had at least one ofthe MYC paralogs amplified. In contrast, the MYCantagonists MGA and MNT were the most frequentlymutated or deleted members, proposing a roleas tumor suppressors.MYCalterations were mutu-ally exclusive withPIK3CA,PTEN,APC,orBRAFalterations, suggesting that MYC is a distinct onco-genic driver. Expression analysis revealed MYC-associated pathways in tumor subtypes, such asimmune response and growth factor signaling; chro-matin, translation, and DNA replication/repair wereconserved pan-cancer. This analysis reveals insightsinto MYC biology and is a reference for biomarkersand therapeutics for cancers with alterations ofMYC or the PMN
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