661 research outputs found
An exploratory study on the utilisation of resilience by middle adolescents in reconstituted families following divorce
Every year thousands of core families disintegrate through divorce, and in the ensuing restructuring of the family system the child has to cope with various development challenges, such as divided membership of two micro family systems and complexities that result at the mesosystemic level. Achieving positive development outcomes in the presence of challenging living circumstances entails complex interactive processes. The aim of the study was to understand the concomitant, reciprocal and/or responsive dynamics of middle adolescents’ use of their inherent resilience potential in their movement back and forth between their two reconstituted family systems after the parents’ divorce. The study was grounded in the qualitative interpretivist paradigm, and used a multiple case study as research design and a narrative format for description. A purposive sample of four white Afrikaans-speaking middle adolescents participated in the research. Findings revealed that middle adolescents of divorced parents utilise their resilience potential in a systemic manner, which requires a solid base provided by the meso system. Hence the utilisation of resilience relies at the very minimum on a functional relationship of cooperation between the biological parents.Keywords: bio-ecological; divorce; meso system; middle adolescent; reconstituted family; resilience; resilience potential; utilisation of resilienc
The influence of cross-cultural interviewing on the generation of data
We investigated the trustworthiness of qualitative data elicited during cross-cultural interviews and problematised data generation as a vital contributor in cross-cultural data collection. An Interview Process Model was adapted from the Response Process Model of Miller and Cannell, and used to understand how responses might be elicited differently in a cross-cultural interviewing situation than during mono-cultural interviewing, and specifically which data would be generated for collection and ultimately for analysis and interpretation. In this study, the concept 'cross-culture' was focused on three dimensions and/or discourses, namely, race, gender, and language. The two researchers were of different race, gender, and language, and were therefore assumed on occasion to evoke different perceptions and responses from interviewees, influencing the data offered for collection. An interview protocol was devised to distinguish a cross-cultural interview from a mono-cultural interview. The findings are discussed with caution and further reverse study is recommended.South African Journal of Education Vol. 26 (4) 2006: pp. 553-56
Influence of the isomeric composition of the acceptor on the performance of organic bulk heterojunction P3HT:bis-PCBM solar cells
We synthesized three isomeric subpopulations of bisadduct analogues of [6,6]-phenyl-C61-butyric acid methyl ester (bis-PCBM) via tether-directed control. Bulk heterojunction solar cells prepared using these isomers together with poly(3-hexylthiophene) (P3HT) resulted in an increase of Jsc from 72.4 to 79.6 A m-2, and an improvement in fill factor from 0.55 to 0.62, both with a Voc of 0.72 V resulting in an overall enhancement of the power conversion efficiency (PCE) from 2.9% to 3.5%, compared to conventional bis-PCBM.
Catalogue of programmes and policies related to regional development and infrastructure ("Baseline assessment")
A baseline assessment, an impact and vulnerability assessment of EU investments in infrastructure and a mitigation potential analysis shall help to generate policy options, which will be appraised in the subsequent phase of the project. In this report we set the stage for the further tasks. The report identifies critical questions and resulting implications concerning the assessment of impacts and vulnerability of infrastructure and infrastructure investments in the EU; describes EU Cohesion Policy; o details the current design of the Structural Funds; describes the issue of environmental and climate change mainstreaming from an EU perspective; presents an exploratory analysis of evidence for climate policy integration based on Member States National Strategic Reference Frameworks (NSRFs); and finally addresses the main research and knowledge gaps that will be addressed in subsequent research within this work package
Deceleration of probe beam by stage bias potential improves resolution of serial block-face scanning electron microscopic images.
Serial block-face scanning electron microscopy (SBEM) is quickly becoming an important imaging tool to explore three-dimensional biological structure across spatial scales. At probe-beam-electron energies of 2.0 keV or lower, the axial resolution should improve, because there is less primary electron penetration into the block face. More specifically, at these lower energies, the interaction volume is much smaller, and therefore, surface detail is more highly resolved. However, the backscattered electron yield for metal contrast agents and the backscattered electron detector sensitivity are both sub-optimal at these lower energies, thus negating the gain in axial resolution. We found that the application of a negative voltage (reversal potential) applied to a modified SBEM stage creates a tunable electric field at the sample. This field can be used to decrease the probe-beam-landing energy and, at the same time, alter the trajectory of the signal to increase the signal collected by the detector. With decelerated low landing-energy electrons, we observed that the probe-beam-electron-penetration depth was reduced to less than 30 nm in epoxy-embedded biological specimens. Concurrently, a large increase in recorded signal occurred due to the re-acceleration of BSEs in the bias field towards the objective pole piece where the detector is located. By tuning the bias field, we were able to manipulate the trajectories of the  primary and secondary electrons, enabling the spatial discrimination of these signals using an advanced ring-type BSE detector configuration or a standard monolithic BSE detector coupled with a blocking aperture
Mental health services in Gauteng, South Africa: A proxy evaluation using pharmaceutical data
Background:Â South African legislation advocates for equitable access to mental healthcare services integrated into general healthcare settings. Mental, neurological, and substance use (MNS) disorders are often comorbid. Pharmacoepidemiology provides indirect evidence of service provision for conditions amenable to medicine treatment.
Aim:Â The study aims to evaluate medicine procurement for MNS disorders at different service levels in the health system.
Setting:Â The Public health sector, Gauteng province formed the setting for the study.
Method:Â A secondary analysis of the Gauteng pharmaceutical database was conducted using Anatomic Therapeutic Chemical (ATC) and defined daily dose (DDD) methodology. Anatomic Therapeutic Chemical classes of medicines for MNS disorders were included. Defined daily doses and costs were calculated per 1000 population served by each facility and service level. Statistical comparisons were made using chi-square testing.
Results: General healthcare settings accounted for 90% (R118 638 248) and specialised hospitals for 10% (R13 685 032) of expenditure on medicines for MNS disorders, procuring 94% (n = 49 442 474) and 6% (n = 3 311 528) of DDDs, respectively. Although district clinics procured 60% of DDDs, they procured the least per 1000 population served, whereas district hospitals procured the most. For almost all ATC classes, procurement differed significantly between municipalities at every service level and between specialised hospitals.
Conclusion:Â In Gauteng province, most medicines for MNS disorders are procured by general healthcare services, but access to care may not be equitable. While population coverage at district clinics appears low, district hospitals may experience the greatest care burden. Research regarding quality of care at each service level is recommended.
Contribution:Â This study provides insight into service provision for MNS disorders
Climate change impacts across Europe and the role of EU regional policy in adaptation
In order to better prioritise adaptation decisions concerning impacts from a changing climate, there is a need for quantitative regional level assessments. In this policy update we provide insights from an impact assessment for three climate-related hazards (heat stress, river flood and forest fire) that is systematic and comparable across different countries in the European Union.
The results show strongest increases in impacts for heat stress and forest fires. Hotspot regions are found in eastern and southern Europe due to their low adaptive capacity. The assessment of risk and capacities to adapt could be a basis to inform the allocation of financial resources in EU regional policy. Yet the reactions of policy makers are sceptic still
Managed Aquifer Recharge as a Tool to Enhance Sustainable Groundwater Management in California
A growing population and an increased demand for water resources have resulted in a global trend of groundwater depletion. Arid and semi-arid climates are particularly susceptible, often relying on groundwater to support large population centers or irrigated agriculture in the absence of sufficient surface water resources. In an effort to increase the security of groundwater resources, managed aquifer recharge (MAR) programs have been developed and implemented globally. MAR is the approach of intentionally harvesting and infiltrating water to recharge depleted aquifer storage. California is a prime example of this growing problem, with three cities that have over a million residents and an agricultural industry that was valued at 47 billion dollars in 2015. The present-day groundwater overdraft of over 100 km3 (since 1962) indicates a clear disparity between surface water supply and water demand within the state. In the face of groundwater overdraft and the anticipated effects of climate change, many new MAR projects are being constructed or investigated throughout California, adding to those that have existed for decades. Some common MAR types utilized in California include injection wells, infiltration basins (also known as spreading basins, percolation basins, or recharge basins), and low-impact development. An emerging MAR type that is actively being investigated is the winter flooding of agricultural fields using existing irrigation infrastructure and excess surface water resources, known as agricultural MAR. California therefore provides an excellent case study to look at the historical use and performance of MAR, ongoing and emerging challenges, novel MAR applications, and the potential for expansion of MAR. Effective MAR projects are an essential tool for increasing groundwater security, both in California and on a global scale. This chapter aims to provide an overview of the most common MAR types and applications within the State of California and neighboring semi-arid regions
Cardiac monitoring in HER2-positive patients on trastuzumab treatment
Trastuzumab prolongs progression-free and overall survival in patients with human epidermal growth factor receptor 2 (HER2) positive breast cancer. However, trastuzumab treatment is hampered by cardiotoxicity, defined as a left ventricular ejection fraction (LVEF) decline with a reported incidence ranging from 3 to 27% depending on variable factors. Early identification of patients at increased risk of trastuzumab-induced myocardial damage is of great importance to prevent deterioration to irreversible cardiotoxicity. Although current cardiac monitoring with multi gated acquisition (MUGA) scanning and/or conventional 2D-echocardiography (2DE) have a high availability, their reproducibility are modest, and more sensitive and reliable techniques are needed such as 3D-echocardiography (3DE) and speckle tracking echocardiography (STE). But which other diagnostic imaging modalities are available for patients before and during trastuzumab treatment? In addition, what is the optimal frequency and duration of cardiac monitoring? At last, which biomarker monitoring strategies are currently available for the identification of cardiotoxicity in patients treated with trastuzumab
A new dynamic framework is required to assess adaptation limits
Anthropogenic climate change is already causing dangerous and widespread disruptions in global ecological and social systems and affects the lives of billions of people around the world. Even with scaled-up risk management and adaptation, the limits of adaptation will often be reached. Currently, very little is known about the degree to which societies can adapt to climate change, and where and when limits to adaptation will be reached. In this paper, we conceptualize adaptation limits through a novel methodological framework, assess adaptation limits along adaptation pathways, and propose a research strategy for empirical and model-based limits assessments based on biophysical and socio-economic data. Assessing limits is central to national and international adaptation policymaking. More efficient adaptation can also help climate mitigation efforts
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