688 research outputs found

    Hume on is-ought: A reinterpretation

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    Pattern and Decoration: An Ideal Vision in American Art, 1975-1985

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    This illustrated catalogue accompanied an exhibition at the Hudson River Museum, Yonkers, New York (October 27, 2007-January 20, 2008). It is the first extended discussion of the Pattern and Decoration movement. This exhibition catalogue was edited by Anne Swartz with an introduction by Michael Botwinick, with essays by Temma Balducci, Arthur C. Danto, John Perrault, and Anne Swartz

    Onset of Mild Cognitive Impairment in Parkinson Disease

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    Objective: Characterize the onset and timing of cognitive decline in Parkinson disease (PD) from the first recognizable stage of cognitively symptomatic PD-mild cognitive impairment (PD-MCI) to PD dementia (PDD). Thirty-nine participants progressed from PD to PDD and 25 remained cognitively normal. Methods: Bayesian-estimated disease-state models described the onset of an individual’s cognitive decline across 12 subtests with a change point. Results: Subtests measuring working memory, visuospatial processing ability, and crystalized memory changed significantly 3 to 5 years before their first nonzero Clinical Dementia Rating and progressively worsened from PD to PD-MCI to PDD. Crystalized memory deficits were the hallmark feature of imminent conversion of cognitive status. Episodic memory tasks were not sensitive to onset of PD-MCI. For cognitively intact PD, all 12 subtests showed modest linear decline without evidence of a change point. Conclusions: Longitudinal disease-state models support a prodromal dementia stage (PD-MCI) marked by early declines in working memory and visuospatial processing beginning 5 years before clinical diagnosis of PDD. Cognitive declines in PD affect motor ability (bradykinesia), working memory, and processing speed (bradyphrenia) resulting in PD-MCI where visuospatial imagery and memory retrieval deficits manifest before eventual development of overt dementia. Tests of episodic memory may not be sufficient to detect and quantify cognitive decline in PD

    Tacit Knowledge in Plato

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    Applying the concept of tacit knowledge to several key areas in Plato\u27s political theory illuminates obscurities and mitigates incoherencies in his thought, revealing a less totalitarian emphasis. It also provides a promising avenue for resolving a central epistemological problem that has occupied Western philosophy since its inception, namely, the fonnulation of a consistent version of skepticism

    Monograph One: Too Old to Learn?

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    Teacher Training Reading Syllabus Monograph One: Too Old to Learn? by Jack Botwinick and Husain Qazilbash in August of 1971

    Maximizing the Benefit of Early-Stage CFD Ventilation Analyses to Reduce Fire and Explosion Hazards

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    PresentationOne of the most significant hazards faced by offshore platforms, FLNGs, and chemical facilities is the risk of explosions resulting from the ignition of flammable clouds due to an unintentional release (leak). Natural ventilation can act as a passive safety measure by helping to dilute and disperse released gases to levels below their flammable limits. Computational fluid dynamics (CFD) ventilation studies are often performed to validate that layouts meet industry criteria or as a step in more complex safety studies; however, often these studies occur during later phases of design after it is “too late” to make basic changes that can drastically alter the risk posed by toxic, fire, and explosion hazards. Many ventilation studies provide results as a single measure, such as “adequate ventilation” measured by the number of air changes per hour (ACH) for a given area. For example, certain hazardous area classifications require that the ventilation must be greater than 12 ACH at least 95% percent of the time (95th percentile ACH). However, the 95th percentile ACH only describes a limited range of the ventilation conditions at the facility and should not be used as the sole means of comparing alternative layouts or making design decisions. A carefully constructed ventilation study that accounts for the nature of facility hazards can provide relatively fast and inexpensive insight into potential safety-oriented optimizations during early stages of facility design. By providing this insight early in design, facilities can be rigorously designed for safety—minimizing the risk (and therefore cost) of late-stage design changes. This paper will present guidance on some of the requirements for and benefits of early-stage ventilation studies. The paper will use specific examples derived from recent work in prioritizing safety in early-stages of design to demonstrate the value of such studies and why the industry needs to move beyond focusing on just the 95th percentile ACH

    Age Differences in Risk: Perceptions, Intentions and Domains

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    Although it is commonly assumed that older people are more cautious and risk averse than their younger counterparts, the research on age differences in risk taking is mixed. While some research has found that older adults are less risk seeking, other research has found the opposite or no differences. One explanation is that age differences vary across risk domains. In two studies, we surveyed three adult age groups ranging in age from 18 to 83 on their risk perceptions and intentions of risky behaviors across several domains. Our studies showed that compared with young adults, older adults tend to see more risk in behaviors in health and ethical domains but less risk in behaviors from the social domain. A similar pattern occurred for participants' intentions of engaging in the risky behaviors. Older adults rated risky behaviors from health and ethical domains as less enjoyable and less likely to produce gains than young adults, whereas they rated risky behaviors from the social domain as more enjoyable, less unpleasant, and less likely to produce losses than young adults. These results suggest that age differences in risk preferences may vary across domains and may result from differing motivations. Copyright © 2015 John Wiley & Sons, Ltd.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/113748/1/bdm1848.pd

    Atrial Fibrillation and Delayed Gastric Emptying

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    Background: Atrial fibrillation and delayed gastric emptying (DGE) are common after pancreaticoduodenectomy. Our aim was to investigate a potential relationship between atrial fibrillation and DGE, which we defined as failure to tolerate a regular diet by the 7 th postoperative day. Methods: We performed a retrospective chart review of 249 patients who underwent pancreaticoduodenectomy at our institution between 2000 and 2009. Data was analyzed with Fisher exact test for categorical variables and Mann-Whitney U or unpaired T-test for continuous variables. Results: Approximately 5 % of the 249 patients included in the analysis experienced at least one episode of postoperative atrial fibrillation. Median age of patients with atrial fibrillation was 74 years, compared with 66 years in patients without atrial fibrillation (p = 0.0005). Patients with atrial fibrillation were more likely to have a history of atrial fibrillation (p = 0.03). 92 % of the patients with atrial fibrillation suffered from DGE, compared to 46 % of patients without atrial fibrillation (p = 0.0007). This association held true when controlling for age. Conclusion: Patients with postoperative atrial fibrillation are more likely to experience delayed gastric emptying. Interventions to manage delayed gastric function might be prudent in patients at high risk for postoperative atrial fibrillation
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