Low Cost Vacuum Chamber Design for Electromagnetic Railgun Operation

This report describes the design and fabrication of a low cost vacuum chamber capable of supporting the operation of an electromagnetic railgun. This would be used to simulate the impact of high velocity impacts in space. The vacuum chamber was constructed out of 10in diameter 10ft PVC pipe with a Wye fitting for viewing impacts during testing. The chamber was designed to accommodate a 6.5in X 6.5in X 60in railgun. The vacuum chamber feedthroughs were designed to be able to carry 1-2Mamps at 8kV to the railgun. The vacuum chamber is capable of reaching 50 Torr and remaining under 100 Torr for 11 minutes. The final cost of the chamber was $1325

SPT 0538–50: Physical Conditions in the Interstellar Medium of a Strongly Lensed Dusty Star-forming Galaxy at z = 2.8

We present observations of SPT-S J053816–5030.8, a gravitationally lensed dusty star-forming galaxy (DSFG) at z = 2.7817 that was first discovered at millimeter wavelengths by the South Pole Telescope. SPT 0538–50 is typical of the brightest sources found by wide-field millimeter-wavelength surveys, being lensed by an intervening galaxy at moderate redshift (in this instance, at z = 0.441). We present a wide array of multi-wavelength spectroscopic and photometric data on SPT 0538–50, including data from ALMA, Herschel PACS and SPIRE, Hubble, Spitzer, the Very Large Telescope, ATCA, APEX, and the Submillimeter Array. We use high-resolution imaging from the Hubble Space Telescope to de-blend SPT 0538–50, separating DSFG emission from that of the foreground lens. Combined with a source model derived from ALMA imaging (which suggests a magnification factor of 21 ± 4), we derive the intrinsic properties of SPT 0538–50, including the stellar mass, far-IR luminosity, star formation rate, molecular gas mass, and—using molecular line fluxes—the excitation conditions within the interstellar medium. The derived physical properties argue that we are witnessing compact, merger-driven star formation in SPT 0538–50 similar to local starburst galaxies and unlike that seen in some other DSFGs at this epoch

Galaxy metallicities depend primarily on stellar mass and molecular gas mass

Aims. We present an analysis of the behaviour of galaxies in a four-dimensional parameter space defined by stellar mass, metallicity, star formation rate, and molecular gas mass. We analyse a combined sample of 227 galaxies that draws from a number of surveys across the redshift range 0 90% of the sample at z ~ 0) and covers >3 decades in stellar mass. Methods. Using principal component analysis, we demonstrate that galaxies in our sample lie on a 2D plane within this 4D parameter space, which is indicative of galaxies that exist in an equilibrium between gas inflow and outflow. Furthermore, we find that the metallicity of galaxies depends only on stellar mass and molecular gas mass. In other words, gas-phase metallicity has a negligible dependence on star formation rate once the correlated effect of molecular gas content is accounted for. Results. The well-known fundamental metallicity relation which describes a close and tight relationship between metallicity and SFR (at fixed stellar mass) is therefore entirely a by-product of the underlying physical relationship with molecular gas mass (through the Schmidt-Kennicutt relation)

CSF Secretion Is Not Altered by NKCC1 Nor TRPV4 Antagonism in Healthy Rats

Background: Cerebrospinal fluid (CSF) secretion can be targeted to reduce elevated intracranial pressure (ICP). Sodium-potassium-chloride cotransporter 1 (NKCC1) antagonism is used clinically. However, supporting evidence is limited. The transient receptor potential vanilloid-4 (TRPV4) channel may also regulate CSF secretion and ICP elevation. We investigated whether antagonism of these proteins reduces CSF secretion. Methods: We quantified CSF secretion rates in male Wistar rats. The cerebral aqueduct was blocked with viscous mineral oil, and a lateral ventricle was cannulated. Secretion rate was measured at baseline and after antagonist administration. Acetazolamide was administered as a positive control to confirm changes in CSF secretion rates. Results: Neither NKCC1, nor TRPV4 antagonism altered CSF secretion rate from baseline, n = 3, t(2) = 1.14, p = 0.37, and n = 4, t(3) = 0.58, p = 0.6, respectively. Acetazolamide reduced CSF secretion by ~50% across all groups, n = 7, t(6) = 4.294, p = 0.005. Conclusions: Acute antagonism of NKCC1 and TRPV4 proteins at the choroid plexus does not reduce CSF secretion in healthy rats. Further investigation of protein changes and antagonism should be explored in neurological disease where increased CSF secretion and ICP are observed before discounting the therapeutic potential of protein antagonism at these sites

Types of albinism in the black Southern Africa population

Background: Oculocutaneous albinism (OCA) is the most common inherited disorder in Southern African blacks and several types have been described. Molecular techniques, where available, can be used to confirm a clinical diagnosis and the type of OCA, if necessary, and for prenatal diagnosis.Objectives: To investigate and classify the different types of albinism commonly found and to determine the clinical implications for each type.Design: A descriptive survey.Setting: Gauteng province, South Africa, and Lesotho.Subjects: Three groups of subjects with OCA (96 from a genetics clinic, 62 from a dermatology clinic, and 31 from community surveys) from the black African population participated.Main outcome measures: Subjects underwent clinical and/or dermatological examinations and were then classified according to type of OCA.Results: Four forms of OCA were identified: most (82%) subjects had OCA2 (a tyrosinasepositive type) with three sub-types: those without large freckles (ephelides) on exposed areas (named OCA 2a in this study), those with such freckles (named OCA 2b), and those with brown albinism (BOCA); the remainder had red/ rufous albinism, ROCA (OCA 3). The four forms could be distinguished from each other clinically without using molecular genetic testing.Conclusion: The most common types of albinism found in the black population of Southern Africa are OCA 2 and OCA 3. Given the high prevalence of the disorder, together with the high risk of skin cancer, and the recent persecution of affected individuals in certain East African countries, these findings and their clinical implications have significance in terms of both education and awareness for health professionals andlay people caring for those with albinism

ALLSMOG: an APEX Low-redshift Legacy Survey for MOlecular Gas. I - molecular gas scaling relations, and the effect of the CO/H2 conversion factor

We present ALLSMOG, the APEX Low-redshift Legacy Survey for MOlecular Gas. ALLSMOG is a survey designed to observe the CO(2-1) emission line with the APEX telescope, in a sample of local galaxies (0.01 < z < 0.03), with stellar masses in the range 8.5 < log(M*/Msun) < 10. This paper is a data release and initial analysis of the first two semesters of observations, consisting of 42 galaxies observed in CO(2-1). By combining these new CO(2-1) emission line data with archival HI data and SDSS optical spectroscopy, we compile a sample of low-mass galaxies with well defined molecular gas masses, atomic gas masses, and gas-phase metallicities. We explore scaling relations of gas fraction and gas consumption timescale, and test the extent to which our findings are dependent on a varying CO/H2 conversion factor. We find an increase in the H2/HI mass ratio with stellar mass which closely matches semi-analytic predictions. We find a mean molecular gas fraction for ALLSMOG galaxies of MH2/M* = (0.09 - 0.13), which decreases with stellar mass. We measure a mean molecular gas consumption timescale for ALLSMOG galaxies of 0.4 - 0.7 Gyr. We also confirm the non-universality of the molecular gas consumption timescale, which varies (with stellar mass) from ~100 Myr to ~2 Gyr. Importantly, we find that the trends in the H2/HI mass ratio, gas fraction, and the non-universal molecular gas consumption timescale are all robust to a range of recent metallicity-dependent CO/H2 conversion factors.Comment: 25 pages, 15 figures. Accepted for publication in MNRA

Molecular gas as the driver of fundamental galactic relations

There has been much recent work dedicated to exploring secondary correlations in the mass-metallicity relation, with significant dependence on both the SFR (SFR) and Hi content being demonstrated. Previously, a paucity of molecular gas data (combined with sample selection bias) hampered the investigation of any such relation with molecular gas content. In this work, we assemble a sample of 221 galaxies from a variety of surveys in the redshift range 0<z<2, to explore the connection between molecular gas content and metallicity. We explore the effect of gas mass on the mass-metallicity relation, finding that the offset from the relation is negatively correlated against both molecular and total gas mass. We then employ a principle component analysis technique to explore secondary dependences in the mass-metallicity relation, finding that the secondary dependence with gas mass is significantly stronger than with SFR, and as such the underlying ‘fundamental metallicity relation' is between stellar mass, metallicity, and gas mass. In particular, the metallicity dependence on SFR is simply a byproduct of the dependence on the molecular gas content, via the Schmidt-Kennicutt relation. Finally, we note that our principle component analysis finds essentially no connection between gas-phase metallicity and the efficiency of star formatio

ALMA observations of atomic carbon in z~4 dusty star-forming galaxies

We present ALMA [CI]($1-0$) (rest frequency 492 GHz) observations for a sample of 13 strongly-lensed dusty star-forming galaxies originally discovered at 1.4mm in a blank-field survey by the South Pole Telescope. We compare these new data with available [CI] observations from the literature, allowing a study of the ISM properties of $\sim 30$ extreme dusty star-forming galaxies spanning a redshift range $2 < z < 5$. Using the [CI] line as a tracer of the molecular ISM, we find a mean molecular gas mass for SPT-DSFGs of $6.6 \times 10^{10}$ M$_{\odot}$. This is in tension with gas masses derived via low-$J$ $^{12}$CO and dust masses; bringing the estimates into accordance requires either (a) an elevated CO-to-H$_2$ conversion factor for our sample of $\alpha_{\rm CO} \sim 2.5$ and a gas-to-dust ratio $\sim200$, or (b) an high carbon abundance $X_{\rm CI} \sim 7\times10^{-5}$. Using observations of a range of additional atomic and molecular lines (including [CI], [CII], and multiple transitions of CO), we use a modern Photodissociation Region code (3D-PDR) to assess the physical conditions (including the density, UV radiation field strength, and gas temperature) within the ISM of the DSFGs in our sample. We find that the ISM within our DSFGs is characterised by dense gas permeated by strong UV fields. We note that previous efforts to characterise PDR regions in DSFGs may have significantly underestimated the density of the ISM. Combined, our analysis suggests that the ISM of extreme dusty starbursts at high redshift consists of dense, carbon-rich gas not directly comparable to the ISM of starbursts in the local Universe.Comment: 21 pages, 12 figures. Accepted for publication in MNRA