47 research outputs found
Tutorial do Endnote web para o BJCVS/RBCCV
At present, many useful tools for reference management are available for use. They can be either off-line softwares or accessible Websites to all users in the internet. Their target is to facilitate the production of scientific text. But, to accomplish that, the featured bibliographic style should be effectively inserted, and the program has to be free. Here in this tutorial, we present Endnote Web®, a bibliographic reference management program comprising these two requirements: it contains the Brazilian Journal of Cardiovascular Surgery reference format and its use is free for charge after sign-in in IP registered terminal in Web of Science®.302246253Diversas ferramentas de gerenciamento de referências bibliográficas estão disponíveis tanto por meio de softwares quanto websites acessíveis para todos utilizadores da Internet. Todas têm um só objetivo: facilitar a produção do texto científico, mas para que isso seja possível necessitam que o estilo bibliográfico da revista em questão esteja disponível e o programa seja grátis. Apresentamos neste tutorial o Endnote Web®, um programa de gerenciamento de referências bibliográficas que cumpre esses dois quesitos: possui o formato de referências exigido pela Revista Brasileira de Cirurgia Cardiovascular e tem utilização grátis, após cadastro em terminal com IP cadastrado na Web of Science®
Surgical treatment for thrombus straddling a patent foramen ovale
We present a case of a 41-year-old female with deep vein thrombosis after abdominal surgery. The patient quickly developed severe pulmonary embolism and stroke representative of paradoxical embolism. Echocardiography showed a thrombus straddling a patent foramen ovale, which was confirmed intraoperatively. An accurate diagnosis and rapid treatment decisions are crucial for preventing patient deterioration in the form of new pulmonary embolisms or stroke31540640
Comparação da solução de histidina-triptofano-alfacetoglutarato com histidina-triptofano-glutamato como agentes cardioplégicos em corações isolados de ratos: estudo imuno-histoquímico
Introduction: Cardiac arrest during heart surgery is a common procedure and allows the surgeon to perform surgical procedures in an environment free of blood and movement. Using a model of isolated rat heart, the authors compare a new cardioplegic solution containing histidine-tryptophan-glutamate
(group 2) with the histidine-tryptophan-alphacetoglutarate (group 1) routinely used by some cardiac surgeons. Objective: To assess caspase, IL-8 and KI-67 in isolated rat hearts using immunohistochemistry. Methods: 20 Wistar male rats were anesthetized and heparinized. The chest was opened, cardioctomy was performed and 40 ml/kg of the appropriate cardioplegic solution was
infused. The hearts were kept for 2 hours at 4°C in the same solution, and thereafter, placed in the Langendorff apparatus for30 minutes with Ringer-Locke solution. Immunohistochemistry analysis of caspase, IL-8, and KI-67 were performed. Results: The concentration of caspase was lower in group 2 and Ki-67 was higher in group 2, both P<0.05. There was no statistical difference between the values of IL-8 between the groups. Conclusion: Histidine-tryptophan-glutamate solution was better than histidine-tryptophan-alphacetoglutarate solution because it reduced caspase (apoptosis), increased KI-67 (cell
proliferation), and showed no difference in IL-8 levels compared to group 1. This suggests that the histidine-tryptophan-glutamate solution was more efficient than the histidine tryptophanalphacetoglutarate for the preservation of hearts of rat cardiomyocytes2918388Introdução: A parada do coração durante a cirurgia cardíaca é procedimento comum e permite que o cirurgião realize os procedimentos cirúrgicos em ambiente isento de sangue e movimento. Os autores comparam, em modelo de coração isolado de rato, uma nova solução cardioplégica com histidina-triptofano-glutamato (grupo 2) com a histidinatriptofano-alfacetoglutarato (grupo 1) já utilizada de rotina por alguns cirurgiões cardíacos. Objetivo: Avaliar por análise imuno-histoquímica a caspase, a IL-8 e KI-67 em corações isolados de ratos. Métodos: 20 ratos machos de raça Wistar foram anestesiados
e heparinizados. O tórax foi aberto, realizado cardiectomia e infundido 40 ml/kg de solução cardioplégica apropriada. Os corações foram mantidos por 2 horas na mesma solução a 4oC e, após esse período, colocados em aparato de Langendorff por30 minutos com solução de Ringer Locke. Foram feitas análises imuno-histoquímicas para caspase, IL-8 e KI-67. Resultados: A concentração de caspase estava menor no grupo 2 e da KI-67 estava mais elevada no grupo 2, ambos com P<0,05. Não houve diferença estatística entre os valores de IL-8 entre os grupos. Conclusão: A solução com histidina-triptofano-glutamato foi melhor que a com histidina-triptofano-cetoglutarato, pois
reduziu a caspase (apoptose), aumentou o KI-67 (proliferação celular) e não apresentou valores diferentes de IL-8 (inflamação e necrose) que no grupo 1. Isso sugere que a solução histidinatriptofano-glutamato foi mais eficiente que a histidinatriptofano-cetoglutarato na preservação dos cardiomiócitos dos corações de ratossem informaçã
ABORDAGEM MULTIDISCIPLINAR NO TRATAMENTO DE DOENÇAS CRÔNICA
Introdução: Sendo uma das principais causas de morte pelo mundo, as doenças crônicas se caracterizam por patologias com desenvolvimento gradual e de longa duração, podendo se estender por cerca de 6 meses ou se perdurar por toda a vida. Classificando-se em transmissíveis, causadas por um agente infeccioso e não transmissíveis frequentemente relacionadas à predisposição genética e estilo de vida. Objetivos: Revisar a abordagem multidisciplinar no tratamento de doenças crônicas. Metodologia: Pesquisa realizada entre abril e maio do ano de 2024, com base em uma revisão integrativa da literatura científica nas bases de dados SciELo e Biblioteca Virtual em Saúde (BVS), utilizando os descritores: "Doenças crônicas" e "Abordagem no tratamento para doenças crônicas". Resultados e discussão: Resultados e discussão: A abordagem multidisciplinar no tratamento de doenças crônicas é fundamental para melhorar os resultados clínicos e a qualidade de vida dos pacientes. A participação de diferentes profissionais de saúde facilita a adesão ao tratamento e reduz maiores complicações. Conclusão: É essencial promover e implementar estratégias que incentivem a colaboração entre diferentes profissionais de saúde no manejo dessas condições, a fim de facilitar o processo do tratamento. 
EFEITOS DA PREMATURIDADE NO DESENVOLVIMENTO INFANTIL
Introduction: Prematurity, defined as birth before 37 completed weeks of gestation, is a condition that affects millions of babies around the world. Prematurity can result in a variety of medical complications and developmental delays that can have lasting, lifelong impacts and can occur for a variety of reasons, from complications during pregnancy to the mother's underlying medical conditions, genetic and environmental factors, becoming one of the main causes of neonatal morbidity and mortality in many countries, representing a significant challenge for health systems and affected families. Objectives: Objectively describe the impacts caused by prematurity on child development and the biggest challenges faced as a result of this factor. Methodology: Research carried out between April and May 2024, based on an integrative review of scientific literature in the SciELo and Virtual Health Library (VHL) databases, using the descriptors: “Prematurity” and “Child development”. Results and discussion: Prematurity has several impacts on child development, from delays in neurological evolution, physical growth to respiratory, immunological and nutritional health. Children born prematurely are at greater risk of developing cognitive and motor delays, attention deficits, hyperactivity and learning difficulties throughout their lives, facing challenges related to physical health and well-being. Conclusion: Premature babies face a series of challenges from the moment of birth, where they often require intensive care to ensure their survival and promote adequate growth and development. Furthermore, throughout childhood, these children often require specialized medical and therapeutic support to monitor and intervene in possible health complications, such as chronic respiratory, visual and hearing problems. Therefore, it is crucial to ensure a sensitive and welcoming care environment, in addition to offering emotional support to parents, to promote the best possible development for these children. Introdução: A prematuridade, definida como o nascimento antes das 37 semanas completas de gestação, é uma condição que afeta milhões de bebês em todo o mundo. A prematuridade pode resultar em uma variedade de complicações médicas e atrasos no desenvolvimento, que podem ter impactos duradouros ao longo da vida, podendo ocorrer por uma variedade de razões, desde complicações durante a gravidez até condições médicas subjacentes da mãe, fatores genéticos e ambientais, se tornando uma das principais causas de morbidade e mortalidade neonatais em muitos países, representando um desafio significativo para os sistemas de saúde e para as famílias afetadas. Objetivos: Descrever de forma objetiva quais os impactos causados pela prematuridade no desenvolvimento infantil e os maiores desafios enfrentados por consequência desse fator. Metodologia: Pesquisa realizada entre abril e maio do ano de 2024, com base em uma revisão integrativa da literatura científica nas bases de dados SciELo e Biblioteca Virtual em Saúde (BVS), utilizando os descritores: "Prematuridade", "Manejo da prematuridade" e "Desafios da prematuridade". Resultados e discussão: A prematuridade acarreta diversos impactos no desenvolvimento infantil, desde atrasos na evolução neurológica, no crescimento físico até a saúde respiratória, imunológica e nutricional. Crianças nascidas prematuramente apresentam maior risco de desenvolver atraso cognitivo e motor, déficits de atenção, hiperatividade e dificuldades de aprendizagem ao longo da vida, enfrentando desafios relacionados à saúde física e ao bem-estar. Conclusão: Os prematuros enfrentam uma série de desafios desde o momento do nascimento, onde muitas vezes necessitam de cuidados intensivos para garantir sua sobrevivência e promover um crescimento e desenvolvimento adequado. Além disso, ao longo da infância, essas crianças frequentemente necessitam de acompanhamento médico e terapêutico especializado para monitoração e intervenção em possíveis complicações de saúde, como problemas respiratórios crônicos, visuais e auditivos. Assim, é crucial garantir um ambiente de cuidados sensível e acolhedor, além de oferecer apoio emocional aos pais, para promover o melhor desenvolvimento possível para essas crianças. 
Catálogo Taxonômico da Fauna do Brasil: setting the baseline knowledge on the animal diversity in Brazil
The limited temporal completeness and taxonomic accuracy of species lists, made available in a traditional manner in scientific publications, has always represented a problem. These lists are invariably limited to a few taxonomic groups and do not represent up-to-date knowledge of all species and classifications. In this context, the Brazilian megadiverse fauna is no exception, and the Catálogo Taxonômico da Fauna do Brasil (CTFB) (http://fauna.jbrj.gov.br/), made public in 2015, represents a database on biodiversity anchored on a list of valid and expertly recognized scientific names of animals in Brazil. The CTFB is updated in near real time by a team of more than 800 specialists. By January 1, 2024, the CTFB compiled 133,691 nominal species, with 125,138 that were considered valid. Most of the valid species were arthropods (82.3%, with more than 102,000 species) and chordates (7.69%, with over 11,000 species). These taxa were followed by a cluster composed of Mollusca (3,567 species), Platyhelminthes (2,292 species), Annelida (1,833 species), and Nematoda (1,447 species). All remaining groups had less than 1,000 species reported in Brazil, with Cnidaria (831 species), Porifera (628 species), Rotifera (606 species), and Bryozoa (520 species) representing those with more than 500 species. Analysis of the CTFB database can facilitate and direct efforts towards the discovery of new species in Brazil, but it is also fundamental in providing the best available list of valid nominal species to users, including those in science, health, conservation efforts, and any initiative involving animals. The importance of the CTFB is evidenced by the elevated number of citations in the scientific literature in diverse areas of biology, law, anthropology, education, forensic science, and veterinary science, among others
Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries
Abstract
Background
Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres.
Methods
This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries.
Results
In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia.
Conclusion
This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries
O estágio supervisionado na formação em Serviço Social: os desafios do tempo presente
O artigo versa sobre a importância do estágio supervisionado em Serviço Social, analisando os principais desafios enfrentados na construção de uma política de estágio durante a pandemia de Covid-19. Além de um levantamento bibliográfico sobre o tema, refletiremos sobre a política e o processo de inserção no estágio desenvolvidos em uma universidade pública durante este período pandêmico. Por fim, indicaremos pistas para a reflexão e a construção de respostas às demandas apresentadas neste cenário de crise sanitária, baseados nesta experiência particular
Tadalafil: Protective Action against the Development of Multiple Organ Failure Syndrome
Abstract Introduction: Multiple organ failure syndrome (MOFS) is a pathology associated to unspecified and severe trauma, characterized by elevated morbidity and mortality. The complex inflammatory MOFS-related reactions generate important ischemia-reperfusion responses in the induction of this syndrome. Nitric oxide elevation, through the activation of cyclic guanosine monophosphate (cGMP), has the potential of counteracting the typical systemic vasoconstriction, and platelet-induced hypercoagulation. Tadalafil would possibly act protectively by reducing cGMP degradation with consequent diffuse vasodilatation, besides reduction of platelet-induced hypercoagulation, thus, preventing multiple organ failure syndrome development. Methods: The experimental protocol was previously approved by an institution animal research committee. Experimental MOFS was induced through the stereotaxic micro-neurosurgical bilateral anterior hypothalamic lesions model. Groups of 10 Wistar rats were divided into: a) Non-operated control; b) Operated control group; c) 2 hours after tadalafil-treated operated group; d) 4 hours after tadalafil-treated operated group; e) 8 hours after post-treated operated group. The animals were sacrificed 24 hours after the neurosurgical procedure and submitted to histopathologic examination of five organs: brain, lungs, stomach, kidneys, and liver. Results: The electrolytic hypothalamic lesions resulted in a full picture of MOFS with disseminated multiple-organs lesions, provoked primarily by diffusely spread micro-thrombi. The treatment with tadalafil 2 hours after the micro-neurosurgical lesions reduced the experimental MOFS lesions development, in a highly significant level (P<0.01) of 58.75%. The treatment with tadalafil, 4 hours after the micro-neurosurgically-induced MOFS lesions, also reduced in 49.71%, in a highly significant level (P<0.01). Finally, the treatment with tadalafil 8 hours after the neurosurgical procedure resulted in a statistically significant reduction of 30.50% (P<0.05) of the experimentally-induced MOFS gravity scores. Conclusion: The phosphodiesterase 5 inhibitor, tadalafil, in the doses and timing utilized, showed to protect against the experimentally-induced MOFS