Caracterització dialectal del Diccionari Aguiló. A partir de les dades de Menorca, Eivissa i Formentera

Treballs Finals de Grau de Filologia Catalana, Facultat de Filologia, Universitat de Barcelona, Curs: 2013-2014, Tutores: Neus Nogué i Maria-Pilar PereaL'obra lexicogràfica de Marià Aguiló és catalogada pels estudiosos com un aplec de materials de la llengua antiga, complementats de manera secundària amb aportacions dialectològiques i onomàstiques. Si bé és cert que quantitativament el cabal d'informació referent a la llengua antiga té un paper predominant al llarg de l'obra, cal no bandejar la importància de la resta de les dades que brinda. En aquest estudi es farà una aproximació al caràcter dialectològic dels materials d'Aguiló, de manera que es prescindirà de la informació històrica, toponímica i antroponímica. El fet que sigui una obra poc estudiada amb valor dialectològic poc conegut, fa necessari un estudi que ajudi a tenir una visió global del Diccionari Aguiló (DA) en aquest camp per poder desmuntar, si cal, alguns prejudicis. Una anàlisi completa de l'obra partint de totes les referències dialectals hauria excedit les dimensions d'aquest estudi, per la qual cosa s'han escollit unes àrees determinades a manera de referència. Malgrat les precaucions necessàries a l'hora d'extrapolar-ne els resultats, una anàlisi d'aquestes característiques ja pot oferir una primera aproximació a l'obra i orientar l'usuari del diccionari en la seva recerca

Carrier Management, versión para dispositivos móviles

La finalidad de este PFC es crear una aplicación nativa para smartphones con sistema operativo Windows Phone que proporcione a los usuarios (Transportistas) la posibilidad de gestionar los viajes que le han sido propuestos o asignados. Se pretende que el uso de la aplicación sea sencillo y claro. Priorizando una navegación intuitiva. La idea del proyecto surge del ámbito laboral, a raíz de algunas implantaciones de sistemas de gestión de transporte consideré que ciertas necesidades de los clientes no estaban bien cubiertas. No obstante, el proyecto no tiene pretensiones de ser una aplicación comercializable. El proyecto ha arrancado con la etapa de análisis. Inicialmente me he marcado los siguientes objetivos: - Aprender el lenguaje C# - Aprender a programar en smartphones Windows. - Aprender a crear un cliente que se comunique con un SOAP Web Service. Tras tener los objetivos definidos, he analizado cuales serían los requisitos que debería garantizar la aplicación, así como elementos que serían necesarios. Del análisis de estos elementos, he seleccionado más adecuados. Con esto aclarado, las siguientes semanas han transcurrido con el diseño las pantallas que conforman la aplicación, revisión de los datos serán necesarios extraer y cual sería el modelo conceptual. Esta parte la he ido revisado a medida que iba descubriendo nuevos controles de Layout en la fase de implantación (Por ejemplo el control Hub). El resultado ha resultado satisfactorio, una aplicación que permite consultar tanto viajes aceptados, como propuestos, permitiendo a los transportistas aceptarlos, ver los detalles de cada viaje, situando en un mapa las paradas y permitiendo confirmar las mismas. La realización de este proyecto me ha permitido refrescar los conocimientos adquiridos en la carrera que creo poder sacar partido laboralmente

New real-time GNSS algorithms for detection and measurement of potential geoeffective stellar flares

Las fulguraciones estelares son incrementos repentinos de radiaciones electromagnéticas en la superficie de una estrella que contienen gran cantidad de energía. Son detectadas por telescopios tales como Swift o Fermi realizando observaciones desde satélites artificiales en órbita baja terrestre. Esta radiación también afecta al contenido total de electrones de la ionosfera terrestre. Esto permite una alternativa para detectar las fulguraciones: detectar el incremento repentino y según un cierto patrón espacial característico del mencionado contenido de electrones, que puede ser procesado usando las medidas transionosféricas en doble frecuencia de los Sistemas de Navegación Global por Satélite (Global Navigation Satellite Systems, GNSS), como por ejemplo GPS. Se propone el algoritmo Blind GNSS Search of Extraterrestrial EUV Sources (BGSEES) para detectar fulguraciones solares sin conocimiento previo de la posición de la fuente, es decir, la posición del Sol relativa a la de la Tierra en la caracterización del algoritmo ante fulguraciones solares conocidas, así como un estudio sobre la viabilidad de la detección de fulguraciones que tienen lugar en estrellas lejanas. El objetivo final es el de confirmar la validez de un nuevo método de detección alternativo al de los telescopios que use datos de libre acceso y sea omnidireccional.Stellar flares are sudden electromagnetic emissions on a star's surface that release large amounts of energy. These flares are detected by telescopes such as Swift or Fermi by performing radiation observations from low Earth orbit. However, the radiation also has an effect on Earth's ionosphere electron content. Another approach for detecting these events is possible: the aforementioned electron content variation can be processed using data from Global Navigation Satellite Systems (GNSS) such as GPS to study the flares. The Blind GNSS Search of Extraterrestrial EUV Sources (BGSEES) algorithm for detecting solar flares without knowing the location of the source, that is, the position of the Sun relative to Earth, is presented, as well as a study on the feasibility of the detection of such events for the challenging scenario of far-away stars, aiming to find an alternative detection method to that of the telescopes and using free, open access data

Link-Level Functional Connectivity Neuroalterations in Autism Spectrum Disorder: A Developmental Resting-State fMRI Study

[EN] Autism spectrum disorder (ASD) is a neurological and developmental disorder whose late diagnosis is based on subjective tests. In seeking for earlier diagnosis, we aimed to find objective biomarkers via analysis of resting-state functional MRI (rs-fMRI) images obtained from the Autism Brain Image Data Exchange (ABIDE) database. Thus, we estimated brain functional connectivity (FC) between pairs of regions as the statistical dependence between their neural-related blood-oxygen-level-dependent (BOLD) signals. We compared FC of individuals with ASD and healthy controls, matched by age and intelligence quotient (IQ), and split into three age groups (50 children, 98 adolescents, and 32 adults), from a developmental perspective. After estimating the correlation, we observed hypoconnectivities in children and adolescents with ASD between regions belonging to the default mode network (DMN). Concretely, in children, FC decreased between the left middle temporal gyrus and right frontal pole (p = 0.0080), and between the left orbitofrontal cortex and right superior frontal gyrus (p = 0.0144). In adolescents, this decrease was observed between bilateral postcentral gyri (p = 0.0012), and between the right precuneus and right middle temporal gyrus (p = 0.0236). These results help to gain a better understanding of the involved regions on autism and its connection with the affected superior cognitive brain functions.This research was partially funded by the Ministerio de Economia y Competitividad (MINECO), through the project BFU2015-64380-C2-2-R. U.P.-R. is funded by the Spanish Ministerio de Educacion, Cultura y Deporte (MECD) under grant FPU13/03537. We are thankful to the initiative ABIDE to provide the huge public release and open sharing autism database what has made possible to carry out this study in better conditions and improve the results obtained significantly.Borràs-Ferrís, L.; Pérez-Ramírez, MÚ.; Moratal, D. (2019). Link-Level Functional Connectivity Neuroalterations in Autism Spectrum Disorder: A Developmental Resting-State fMRI Study. Diagnostics. 9(1):1-10. https://doi.org/10.3390/diagnostics9010032S11091Hull, J. V., Dokovna, L. B., Jacokes, Z. J., Torgerson, C. M., Irimia, A., & Van Horn, J. D. (2017). Resting-State Functional Connectivity in Autism Spectrum Disorders: A Review. Frontiers in Psychiatry, 7. doi:10.3389/fpsyt.2016.00205Mertz, L. (2017). Sharing Data to Solve the Autism Riddle: An Interview with Adriana Di Martino and Michael Milham of ABIDE. IEEE Pulse, 8(6), 6-9. doi:10.1109/mpul.2017.2750819Cociu, B. A., Das, S., Billeci, L., Jamal, W., Maharatna, K., Calderoni, S., … Muratori, F. (2018). Multimodal Functional and Structural Brain Connectivity Analysis in Autism: A Preliminary Integrated Approach With EEG, fMRI, and DTI. IEEE Transactions on Cognitive and Developmental Systems, 10(2), 213-226. doi:10.1109/tcds.2017.2680408Dekhil, O., Hajjdiab, H., Shalaby, A., Ali, M. T., Ayinde, B., Switala, A., … El-Baz, A. (2018). Using resting state functional MRI to build a personalized autism diagnosis system. PLOS ONE, 13(10), e0206351. doi:10.1371/journal.pone.0206351Rogers, B. P., Morgan, V. L., Newton, A. T., & Gore, J. C. (2007). Assessing functional connectivity in the human brain by fMRI. Magnetic Resonance Imaging, 25(10), 1347-1357. doi:10.1016/j.mri.2007.03.007Cheng, W., Rolls, E. T., Gu, H., Zhang, J., & Feng, J. (2015). Autism: reduced connectivity between cortical areas involved in face expression, theory of mind, and the sense of self. Brain, 138(5), 1382-1393. doi:10.1093/brain/awv051Lynch, C. J., Uddin, L. Q., Supekar, K., Khouzam, A., Phillips, J., & Menon, V. (2013). Default Mode Network in Childhood Autism: Posteromedial Cortex Heterogeneity and Relationship with Social Deficits. Biological Psychiatry, 74(3), 212-219. doi:10.1016/j.biopsych.2012.12.013Uddin, L. Q., Supekar, K., Lynch, C. J., Khouzam, A., Phillips, J., Feinstein, C., … Menon, V. (2013). Salience Network–Based Classification and Prediction of Symptom Severity in Children With Autism. JAMA Psychiatry, 70(8), 869. doi:10.1001/jamapsychiatry.2013.104Di Martino, A., Kelly, C., Grzadzinski, R., Zuo, X.-N., Mennes, M., Mairena, M. A., … Milham, M. P. (2011). Aberrant Striatal Functional Connectivity in Children with Autism. Biological Psychiatry, 69(9), 847-856. doi:10.1016/j.biopsych.2010.10.029Washington, S. D., Gordon, E. M., Brar, J., Warburton, S., Sawyer, A. T., Wolfe, A., … VanMeter, J. W. (2013). Dysmaturation of the default mode network in autism. Human Brain Mapping, 35(4), 1284-1296. doi:10.1002/hbm.22252Assaf, M., Jagannathan, K., Calhoun, V. D., Miller, L., Stevens, M. C., Sahl, R., … Pearlson, G. D. (2010). Abnormal functional connectivity of default mode sub-networks in autism spectrum disorder patients. NeuroImage, 53(1), 247-256. doi:10.1016/j.neuroimage.2010.05.067Weng, S.-J., Wiggins, J. L., Peltier, S. J., Carrasco, M., Risi, S., Lord, C., & Monk, C. S. (2010). Alterations of resting state functional connectivity in the default network in adolescents with autism spectrum disorders. Brain Research, 1313, 202-214. doi:10.1016/j.brainres.2009.11.057Kennedy, D. P., & Courchesne, E. (2008). The intrinsic functional organization of the brain is altered in autism. NeuroImage, 39(4), 1877-1885. doi:10.1016/j.neuroimage.2007.10.052Mueller, S., Keeser, D., Samson, A. C., Kirsch, V., Blautzik, J., Grothe, M., … Meindl, T. (2013). Convergent Findings of Altered Functional and Structural Brain Connectivity in Individuals with High Functioning Autism: A Multimodal MRI Study. PLoS ONE, 8(6), e67329. doi:10.1371/journal.pone.0067329Von dem Hagen, E. A. H., Stoyanova, R. S., Baron-Cohen, S., & Calder, A. J. (2012). Reduced functional connectivity within and between ‘social’ resting state networks in autism spectrum conditions. Social Cognitive and Affective Neuroscience, 8(6), 694-701. doi:10.1093/scan/nss053Uddin, L. Q., Supekar, K., & Menon, V. (2013). Reconceptualizing functional brain connectivity in autism from a developmental perspective. Frontiers in Human Neuroscience, 7. doi:10.3389/fnhum.2013.00458Kana, R. K., Uddin, L. Q., Kenet, T., Chugani, D., & Müller, R.-A. (2014). Brain connectivity in autism. Frontiers in Human Neuroscience, 8. doi:10.3389/fnhum.2014.00349Beckmann, C. F., & Smith, S. M. (2004). Probabilistic Independent Component Analysis for Functional Magnetic Resonance Imaging. IEEE Transactions on Medical Imaging, 23(2), 137-152. doi:10.1109/tmi.2003.822821Cole. (2010). Advances and pitfalls in the analysis and interpretation of resting-state FMRI data. Frontiers in Systems Neuroscience. doi:10.3389/fnsys.2010.00008Etzel, J. A., Gazzola, V., & Keysers, C. (2009). An introduction to anatomical ROI-based fMRI classification analysis. Brain Research, 1282, 114-125. doi:10.1016/j.brainres.2009.05.090Di Martino, A., Yan, C.-G., Li, Q., Denio, E., Castellanos, F. X., Alaerts, K., … Milham, M. P. (2013). The autism brain imaging data exchange: towards a large-scale evaluation of the intrinsic brain architecture in autism. Molecular Psychiatry, 19(6), 659-667. doi:10.1038/mp.2013.78Cameron, C., Yassine, B., Carlton, C., Francois, C., Alan, E., András, J., … Pierre, B. (2013). The Neuro Bureau Preprocessing Initiative: open sharing of preprocessed neuroimaging data and derivatives. Frontiers in Neuroinformatics, 7. doi:10.3389/conf.fninf.2013.09.00041Xu, T., Yang, Z., Jiang, L., Xing, X.-X., & Zuo, X.-N. (2015). A Connectome Computation System for discovery science of brain. Science Bulletin, 60(1), 86-95. doi:10.1007/s11434-014-0698-3Desikan, R. S., Ségonne, F., Fischl, B., Quinn, B. T., Dickerson, B. C., Blacker, D., … Killiany, R. J. (2006). An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest. NeuroImage, 31(3), 968-980. doi:10.1016/j.neuroimage.2006.01.021Cole, M. W., Yang, G. J., Murray, J. D., Repovš, G., & Anticevic, A. (2016). Functional connectivity change as shared signal dynamics. Journal of Neuroscience Methods, 259, 22-39. doi:10.1016/j.jneumeth.2015.11.011Smith, S. M., Jenkinson, M., Woolrich, M. W., Beckmann, C. F., Behrens, T. E. J., Johansen-Berg, H., … Matthews, P. M. (2004). Advances in functional and structural MR image analysis and implementation as FSL. NeuroImage, 23, S208-S219. doi:10.1016/j.neuroimage.2004.07.051Jenkinson, M., Beckmann, C. F., Behrens, T. E. J., Woolrich, M. W., & Smith, S. M. (2012). FSL. NeuroImage, 62(2), 782-790. doi:10.1016/j.neuroimage.2011.09.015Winkler, A. M., Ridgway, G. R., Webster, M. A., Smith, S. M., & Nichols, T. E. (2014). Permutation inference for the general linear model. NeuroImage, 92, 381-397. doi:10.1016/j.neuroimage.2014.01.060Bhaumik, R., Pradhan, A., Das, S., & Bhaumik, D. K. (2018). Predicting Autism Spectrum Disorder Using Domain-Adaptive Cross-Site Evaluation. Neuroinformatics, 16(2), 197-205. doi:10.1007/s12021-018-9366-0Cavanna, A. E., & Trimble, M. R. (2006). The precuneus: a review of its functional anatomy and behavioural correlates. Brain, 129(3), 564-583. doi:10.1093/brain/awl004Rolls, E. T. (2004). The functions of the orbitofrontal cortex. Brain and Cognition, 55(1), 11-29. doi:10.1016/s0278-2626(03)00277-xBeer, J. S., John, O. P., Scabini, D., & Knight, R. T. (2006). Orbitofrontal Cortex and Social Behavior: Integrating Self-monitoring and Emotion-Cognition Interactions. 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The Latest Occurrence of Stephanorhinus hundsheimensis (Rhinocerotidae) in Europe: The Skeletons from the Cova del Rinoceront Site (Castelldefels, Barcelona).

New rhino remains recovered from Cova del Rinoceront (Castelldefels, Barcelona) confirm the presence of Stephanorhinus hundsheimensis (Toula, 1902) at the site and the taxon’s persistence until the late Middle–early Upper Pleistocene in Europe, that is, its latest documented occurrence. The three individuals recovered from the site are compared with specimens of other Pleistocene species, including those of S. hemitoechus, S. kirchbergensis and Coelodonta antiquitatis, but their anatomical characteristics (a long skull, moderate occipital elevation, partial nasal septum, and slender zygomatic arch) do not coincide with the latter’s documented features. Certain similarities are found with the most frequently occurring rhinocerotid at that time in the Iberian Peninsula, S. hemitoechus, but the cranial features of the latter differ. The anatomical characteristics of the Cova del Rinoceront individuals coincide most closely with those of S. hundsheimensis (i.e., a high occipital face, with rounded proximolateral angles and oblique lateral borders, as well as the frontoparietal angle, and facial development). Despite the marked overlaps in the general measurements of S. hundsheimensis and S. hemitoechus, many (cranial and postcranial) dimensions of the Cova del Rinoceront individuals coincide more closely with those of the former, although some bone proportions are more similar to those of the latter specimens. Therefore, S. kirchbergensis and C. antiquitatis can be discarded as they tend to be larger, more robust species

Analysis of parental behaviour and attitude in sports and its relation with the sports performance

The aim of the present investigation was to analyse the relation between parental behaviour and other socio-demographic and sportive variables with their children’s sports performance. A sample of 223 parents (46.2% men; 53.4% women) of 223 youth athletes (77.13% boys; 22.87% girls; Mage = 11.66 years; DE = 1.60) were asked. All of them belonged to 13 grassroots teams: football (soccer) (48.9%), basketball (13.5%), volleyball (34.1%) and handball (3.6%) of different categories: U-12 (36.8%), U-13 (48%) and U-15 (15.2%). A retrospective ex post facto design of unique group was planned. The questionnaire Análisis del Comportamiento y Actuación de los Padres y Madres en el Deporte (ACAPMD) was used. Differences statistically significant were detected between parental behaviour to the sports, socio-demographic variables (age and athlete’s gender, parents’ gender and geographical zone) and sports variables (sports category and sport played) with the sports performance. An age increase above the mean, it will make more probable a high sports performance. The clubs of out of Palma registered the highest percentage of sports performance and low sports performance. The highest percentage of high performance was registered in men and women highlighted in medium and low performance. The highest percentages of high and medium performance were registered when the mothers answered the questionnaire. The highest percentage of high and low performance was registered in basketball. And, the highest percentage of sports performance was in U-12’s category, U-13’s category highlighted in low performance and U-15’s category highlighted in medium performance.This research was conducted, in part, thanks to a grant (Values in sport) from Conselleria de Transparència, Cultura i Esport. Govern de les Illes Balears (Spain). Project number (06605)

Juvenile hormone biosynthesis in adult Blattella germanica requires nuclear receptors Seven-up and FTZ-F1

In insects, the transition from juvenile development to the adult stage is controlled by juvenile hormone (JH) synthesized from the corpora allata (CA) glands. Whereas a JH-free period during the last juvenile instar triggers metamorphosis and the end of the growth period, the reappearance of this hormone after the imaginal molt marks the onset of reproductive adulthood. Despite the importance of such transition, the regulatory mechanism that controls it remains mostly unknown. Here, using the hemimetabolous insect Blattella germanica, we show that nuclear hormone receptors Seven-up-B (BgSvp-B) and Fushi tarazu-factor 1 (BgFTZ-F1) have essential roles in the tissue-and stage-specific activation of adult CA JH-biosynthetic activity. Both factors are highly expressed in adult CA cells. Moreover, RNAi-knockdown of either BgSvp-B or BgFTZ-F1 results in adult animals with a complete block in two critical JH-dependent reproductive processes, vitellogenesis and oogenesis. We show that this reproductive blockage is the result of a dramatic impairment of JH biosynthesis, due to the CA-specific reduction in the expression of two key JH biosynthetic enzymes, 3-hydroxy-3-methylglutaryl coenzyme A synthase-1 (BgHMG-S1) and HMG-reductase (BgHMG-R). Our findings provide insights into the regulatory mechanisms underlying the specific changes in the CA gland necessary for the proper transition to adulthood.Support for this research was provided by the Spanish MINECO (grants BFU2009-10571 and CGL2014-55786-P to D.M. and CGL2012-36251 and CGL2015-64727-P to X.B.) and by the Catalan Government (2014 SGR 619 to D.M., J.L.M. and X.B.). The research has also benefited from FEDER funds. F.B.-C. is a recipient of a pre-doctoral research Grant from the MICINN. C.N. is a recipient of a postdoctoral research grant from CSIC. O.M. is recipient of a pre-doctoral research grant from Generalitat de Catalunya.Peer Reviewe

Insights into the Antimicrobial Mechanism of Action of Human RNase6 : Structural Determinants for Bacterial Cell Agglutination and Membrane Permeation

Human Ribonuclease 6 is a secreted protein belonging to the ribonuclease A (RNaseA) superfamily, a vertebrate specific family suggested to arise with an ancestral host defense role. Tissue distribution analysis revealed its expression in innate cell types, showing abundance in monocytes and neutrophils. Recent evidence of induction of the protein expression by bacterial infection suggested an antipathogen function in vivo. In our laboratory, the antimicrobial properties of the protein have been evaluated against Gram-negative and Gram-positive species and its mechanism of action was characterized using a membrane model. Interestingly, our results indicate that RNase6, as previously reported for RNase3, is able to specifically agglutinate Gram-negative bacteria as a main trait of its antimicrobial activity. Moreover, a side by side comparative analysis with the RN6(1-45) derived peptide highlights that the antimicrobial activity is mostly retained at the protein N-terminus. Further work by site directed mutagenesis and structural analysis has identified two residues involved in the protein antimicrobial action (Trp1 and Ile13) that are essential for the cell agglutination properties. This is the first structure-functional characterization of RNase6 antimicrobial properties, supporting its contribution to the infection focus clearance

Proceso de Bolonia (VI): aprendiendo comunicación para la salud en el Grado de Medicina

La comunicación forma parte de la actividad clínica y en ocasiones determina el éxito o fracaso del proceso asistencial. Sin embargo, no ha sido reconocida en los planes de estudio del Estado español hasta muy recientemente, sobre todo con el impulso del llamado 'Plan Bolonia'. En el año 2009 se aprobó en la Facultad de Medicina de la Universitat de Barcelona un nuevo plan docente que proponía incorporar la enseñanza de la comunicación en las materias clínicas y pre-clínicas, contabilizando entre 3 y 6 créditos europeos (ECTS), como competencia transversal. El presente artículo aborda el diseño de esta competencia, los pros y contras, cómo se inserta en diferentes asignaturas y cómo puede evaluarse