175 research outputs found

    An Dynamic Voltage Regulator For HVDC System On Low Power DC Line With Series Active Power Filter And Reducing Repulsion To The Transmitting Station

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    Harmonics in HVDC power systems, which are caused by highly non-linear devices, affect its performance. Therefore, the main concern of power engineers in power system design and operation have been controlling and eliminating such repulsion. In respect of this, HVDC power system repulsion analysis is, therefore, imperative in power system planning, control and operation. It is worthy of note that, different alternatives of filter design should be considered before making final decision on filter Configuration. In this paper the reduction of harmonics in the HVDC power transmission system by implementing the active power filter. Also the power factor is increased drastically by reducing the current harmonics in the load side. The solar PV output can be presented and analyzed with help of boost converter in order to proof that the solar output voltage can be increased by the boost converter. The series active power filter appears to be a viable solution for eliminating repulsion currents and current transient condition. Shunt active power filter compensates current by injecting equal voltage compensation is created by nonlinear loads

    SCIENTOMETRIC ANALYSIS OF DIABETES RESEARCH OUTPUT DURING THE YEAR 2014-2018: Indexed by Web of Science

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    To assess diabetes research productivity in India and analysis to various parameters in the view of the scientometric analytical study. Collections include (Articles, Reviews, Meeting Abstracts, Letters and book chapter), etc. published 8016 diabetes journals in 2014 – 2018 were screened with the Web of Science database (Clarivate Analytics). The study mainly focused on the Author and journal wise distribution, Year and country wise output and Institution wise collaboration are discussed in this paper. Most of the research articles published from India, between 2016 and 2017 has been published more journals. All India Institute of Medical Science has published highest journals compare with the other institutions

    A study on Red Blood Cell count, Distribution Width and Neutrophil/ Lymphocyte Ratio as Markers of Vascular Inflammation in the Early Detection of Non Proliferative Diabetic Retinopathy.

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    About 100 Type-II Diabetic patients with / without visual symptoms attending Ophthalmology and diabetology OPDs after satisfying the Inclusion/ Exclusion Criteria will be included in the study. All patients will be subjected to symptom analysis, clinical examination and laboratory investigation. Final results will be analyzed by SPSS statistical software. RESULTS Our study was a Cross-sectional study conducted among 100 Type-II diabetic patients between 30-50 years of age. Two group were assigned according to the severity of Diabetic Retinopathy. One is a mild grade and another is a moderate grade. NLR, RDW and RBC count were analyzed in this study population. Also HBAIC and blood glucose levels were correlated with them. Statistical analysis was done with SPSS Software. Results were studied using unpaired t-test, chi-square test and Pearson coefficient Correlation. 2 CONCLUSION From our study we conclude that, both NLR and RDW are useful markers of vascular inflammation for 1) Early diagnosis of Non-proliferative diabetic retinopathy. 2) Assessing the severity of non proliferative Diabetic Retinopathy as mild or moderate grades. 3) Also their prediction of uncontrolled glycaemic status since they correlate well with HBA1C and blood glucose levels

    Inquiry of inclined magnetic field effects on Walter –B nanofluid flow with heat generation / absorption

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    The article deals with Walter-B nanoliquid flow towards a extending surface with inclined magnetic field effects. Thermal relaxation analysis is made by non fourier heat flux model. Radiation, heat generation / absorption impacts are included. The non linear Partial governing systems are rebuild into nonlinear ordinary systems with the assist of proper similarity transformations. The graphical results are portrayed for velocity, concentration and temperature profile. The physical entitles of heat and mass transfer rates are graphically reported. The comparission with previous results notified the excellent agreement

    A PROSPECTIVE STUDY ON RISK FACTORS OF IRON DEFICIENCY ANEMIA IN PREGNANT WOMEN AND THEIR MANAGEMENT

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    Objective: Iron deficiency anemia during pregnancy leads to preterm birth, low birth weight and increases the incidence of postpartum hemorrhage (PPH) and the reason for the incidence of PPH is higher in India compared with the rest of the world. In this study, our main goal was to find out the risk factors and complications of iron deficiency anemia and their management in pregnant women. Methods: It is a prospective study done at Obstetrics and Gynecology Department in Government District Headquarters Hospital, Tiruppur. All subjects were analyzed in full detail and hemoglobin estimation was also done to the patients. Results: Study found that 52% shows moderate anemia followed by 30% mild and 18% severe, respectively. Risk factors are found in 55% cases. Study found an association between risk factors and severity of anemia. Conclusion: Iron deficiency anemia continues to be the commonest etiology of anemia in pregnancy. The prevalence of iron deficiency in a pregnant woman is amongst the highest in the world. Untreated iron deficiency has significant adverse feto-maternal consequences. Iron supplementation and antenatal care are the basic requirements to prevent anemia

    Design of metamaterial based antipodal Vivaldi antenna

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    100-104The advanced devices for Ultrawide Band (UWB), 5G, and Millimeter-wave communication demand an antenna that can handle massive data rates and provide high gain and better radiation patterns as a solution for most current wireless communication complications. Many different antennas have been designed. The Antipodal Vivaldi Antenna (AVA) has drawn the attention of most of the researchers because of its high gain, wider bandwidth, less radiation loss, and consistent radiation pattern. Different methods have been presented to enhance the performance of AVA. These different methods include varying the substrate material, radiating element’s flaring shape, slots, and feeding techniques. Further, AVA performance can be enhanced by incorporating corrugation, dielectric lens, patch in between two flares, balanced AVA (BAVA), metamaterial, and AVA array. Implementing enhancement techniques in AVA modifies the electrical and physical properties, which in turn improves its performance. This paper discusses a detailed review of Metamaterial-based Antipodal Vivaldi Antennas and a comparison of the antenna parameters

    Therapeutic Challenge with a CDK 4/6 Inhibitor Induces an RB-Dependent SMAC-Mediated Apoptotic Response in Non-Small Cell Lung Cancer.

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    Purpose: The retinoblastoma tumor suppressor (RB), a key regulator of cell-cycle progression and proliferation, is functionally suppressed in up to 50% of non-small cell lung cancer (NSCLC). RB function is exquisitely controlled by a series of proteins, including the CyclinD-CDK4/6 complex. In this study, we interrogated the capacity of a CDK4/6 inhibitor, palbociclib, to activate RB function. Experimental Design and Results: We employed multiple isogenic RB-proficient and -deficient NSCLC lines to interrogate the cytostatic and cytotoxic capacity of CDK 4/6 inhibition in vitro and in vivo We demonstrate that while short-term exposure to palbociclib induces cellular senescence, prolonged exposure results in inhibition of tumor growth. Mechanistically, CDK 4/6 inhibition induces a proapoptotic transcriptional program through suppression of IAPs FOXM1 and Survivin, while simultaneously augmenting expression of SMAC and caspase-3 in an RB-dependent manner. Conclusions: This study uncovers a novel function of RB activation to induce cellular apoptosis through therapeutic administration of a palbociclib and provides a rationale for the clinical evaluation of CDK 4/6 inhibitors in the treatment of patients with NSCLC

    Make in India – Challenges and Opportunities

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    Make in India is new national initiative program by government aimed at transforming India into a global manufacturing hub. It includes a slew of proposals aimed at inviting both domestic and foreign companies to invest in India and help it become a manufacturing powerhouse. “ZERO DEFECT AND ZERO EFFECT”slogan was defined by our prime minister Narendera Modi, as part of Make in India programme which handle innovative processes materials, enhance skill development,technologies and the manufacturing mechanism is guided to make the goods that are defect free and have no negative environmental or ecological effects. Main mission of this project is to make the production India and sell the products all over the world. The primary focus of "Make in India" project is to enhance the annual growth rate of 25 sectors from 12-14 % to improve GDP rate and to create 100 million job opportunities within 2022. The purpose of this study is to explain the concept of Make in India campaign, its importance, schemes,and its impact on Indian economy. This paper also proposes to identify the challenges and opportunities as well as recommended possible solutions to deal with the same
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