Modelo para avaliação do serviço de dispensação de medicamentos na atenção básica à saúde

OBJECTIVE To develop a model for evaluating the efficacy of drug-dispensing service in primary health care. METHODS An efficacy criterion was adopted to determine the level of achievement of the service objectives. The evaluation model was developed on the basis of a literature search and discussions with experts. The applicability test of the model was conducted in 15 primary health care units in the city of Florianópolis, state of Santa Catarina, in 2010, and data were recorded in structured and pretested questionnaires. RESULTS The model developed was evaluated using five dimensions of analysis for analysis. The model was suitable for evaluating service efficacy and helped to identify the critical points of each service dimension. CONCLUSIONS Adaptations to the data collection technique may be required to adjust for the reality and needs of each situation. The evaluation of the drug-dispensing service should promote adequate access to medications supplied through the public health system.OBJETIVO Elaborar modelo para avaliação da eficácia do serviço de dispensação de medicamentos na atenção básica à saúde.. MÉTODOS Foi adotado critério de eficácia para verificar o grau em que são alcançados os objetivos do serviço. O modelo de avaliação foi elaborado com base na literatura sobre o tema e na discussão com especialistas. O teste de aplicabilidade do modelo foi realizado em Florianópolis, SC, em 2010, em 15 unidades de saúde, com observação direta em formulário próprio para coleta de dados.. RESULTADOS O modelo apresentou-se adequado para avaliação da eficácia do serviço, elaborado com cinco dimensões de análise, permitindo identificar os pontos críticos de cada uma das dimensões do serviço.. CONCLUSÕES Adaptações à técnica de coleta de dados poderão ser necessárias para a realidade e necessidade de cada situação. A qualificação da dispensação deve propiciar o acesso qualificado aos medicamentos disponibilizados pela rede pública

Phosphorylation of human plasminogen activators and plasminogen

AbstractPlasminogen (PG), urokinase-type plasminogen activator (u-PA) and tissue-type PA (t-PA) are the main molecules involved in fibrinolysis and in many other physiological and pathological processes. In the present study we report that human t-PA, purified from human melanoma cells, and PG, purified from human plasma, both contain P-Tyr residues, as revealed by immunoblotting analyses with monoclonal anti-P-Tyr antibodies. In addition HPLC amino acid analysis of acid-hydrolyzed t-PA, PG and u-PA, shows that: (i)P-Ser and P-Tyr residues are present in t-PA; (ii)P-Thr and P-Tyr are present in PG; (iii) P-Ser, P-Thr and P-Tyr are present in u-PA. The utilization of monoclonal anti-P-Ser and anti-P-Thr antibodies in immunoblotting experiments has confirmed these data which indicate that phosphorylation is a common feature of PAs and of PG

Phases, Similarities and Differences between the Cases of Dictatorships and Political Economy in Argentina, 1966-1973 and 1976-1983, and Brazil, 1964-1985

Argentina y Brasil vivieron dictaduras cívico-militares durante las décadas de 1960 y 1980. En Argentina, la experiencia se dividió en dos etapas: en la primera (1966-1973) se persiguió una estrategia industrializadora; mientras que en la segunda (1976-1983), se alineó al proceso neoliberal. En Brasil, la dictadura (1964-1985) se inició en pleno auge de la etapa desarrollista y no abandonó ese patrón económico. En este artículo se analiza la evolución de ambas experiencias desde la economía política; se indaga en las formas que asumen los procesos de acumulación de capital en cada caso, al analizar cómo las dictaduras incidieron en los mismos, así como los objetivos ideológicos y de política económica que persiguieron. La comparación pone en debate aspectos como las condicionantes del mercado mundial en las dinámicas internas de cada país y las alianzas de clases sociales para entender las similitudes y diferencias entre los dos países.Argentina and Brazil experienced military civic dictatorships during the 1960s and 1980s. In Argentina, the experience is divided into two stages: in the rst one (1966-1973), the country pursued an industrializing strategy; in the second one (1976-1983), it started a neoliberal process. In Brazil, the dictatorship (1964-1985) began in the context of the developmental stage and did not abandon that economic pattern. This article analyzes the evolution of both experiences with the elements of political economy; it investigates the processes of capital accumulation in each case, by analyzing how the dictatorships a ected them, as well as the ideological and economic policy objectives they searched. This comparison discusses aspects such as the conditions of the world market in the internal dynamics of each country and social class alliances to understand the similarities and di erences between both countries.Facultad de Humanidades y Ciencias de la Educació

Phases, Similarities and Differences between the Cases of Dictatorships and Political Economy in Argentina, 1966-1973 and 1976-1983, and Brazil, 1964-1985

Argentina y Brasil vivieron dictaduras cívico-militares durante las décadas de 1960 y 1980. En Argentina, la experiencia se dividió en dos etapas: en la primera (1966-1973) se persiguió una estrategia industrializadora; mientras que en la segunda (1976-1983), se alineó al proceso neoliberal. En Brasil, la dictadura (1964-1985) se inició en pleno auge de la etapa desarrollista y no abandonó ese patrón económico. En este artículo se analiza la evolución de ambas experiencias desde la economía política; se indaga en las formas que asumen los procesos de acumulación de capital en cada caso, al analizar cómo las dictaduras incidieron en los mismos, así como los objetivos ideológicos y de política económica que persiguieron. La comparación pone en debate aspectos como las condicionantes del mercado mundial en las dinámicas internas de cada país y las alianzas de clases sociales para entender las similitudes y diferencias entre los dos países.Argentina and Brazil experienced military civic dictatorships during the 1960s and 1980s. In Argentina, the experience is divided into two stages: In the first one (1966-1973), the country pursued an industrializing strategy; in the second one (1976-1983), it started a neoliberal process. In Brazil, the dictatorship (1964-1985) began in the context of the developmental stage and did not abandon that economic pattern. This article analyzes the evolution of both experiences with the elements of political economy; it investigates the processes of capital accumulation in each case, by analyzing how the dictatorships affected them, as well as the ideological and economic policy objectives they searched. This comparison discusses aspects such as the conditions of the world market in the internal dynamics of each country and social class alliances to understand the similarities and differences between both countries.Fil: Bona, Leandro Marcelo. Facultad Latinoamericana de Ciencias Sociales. Sede Académica Argentina Buenos Aires. Área de Economía y Tecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Saavedra 15. Instituto de Investigaciones Sociales de América Latina. - Facultad Latinoamericana de Ciencias Sociales. Instituto de Investigaciones Sociales de América Latina; ArgentinaFil: Paéz, Sergio M.. Universidade Federal do Rio de Janeiro; Brasi

Structural analysis of Fe/Ni(001) films by photoelectron diffraction

The structure of Fe films, epitaxially grown on Ni(001), has been studied in the 0-14 ML coverage range by means of photoelectron diffraction (PD) in the forward scattering regime. Quantitative analysis by a multiple scattering approach has been performed on Fe films at a coverage of 3 and 7 ML. Analysis of the 3-ML data showed that growth was not layer-by-layer but rather occurred through islands nucleation and that transition from the pseudomorphic fee to the bcc phase was located in this early stage of growth. In fact, best fit was obtained by calculations on a 2 ML bcc(110)/3 ML fcc(001) Fe film with the bcc[111]parallel to fcc[110] in-plane orientation. Interlayer spacings of 2.05 +/- 0.068 Angstrom, 2.01 +/- 0.03 Angstrom, and 1.85 +/- 0.03 Angstrom were found in the bcc region, between bcc and fee layers and in the fee region, respectively. Best-fit in-plane nearest-neighbors (n-n) distance was 2.49 +/- 0.02 Angstrom, in registry with that of the Ni substrate. To analyze the 7-ML data a 4 ML bcc(110)/3 ML fcc(001) film was employed, varying the fitting parameters in the bcc region only. Best fit was obtained for an interlayer spacing of 2.04 +/- 0.04 Angstrom and in plane n-n distance of 2.47 +/- 0.01 Angstrom. At 14 ML the PD pattern collected over a 94 degrees azimuthal range displayed symmetry around the [110] substrate direction, which was explained by the equipopulation of the 4 bcc(110) domains satisfying the bcc[111]parallel to fcc[110] alignment

Eocene whales from the La Meseta Formation, Antarctica: Clues on the radiation of Pelagiceti in the Southern Hemisphere

Eocene cetacean records, mainly from the northern hemisphere, documented one of the most outstanding processes of mammalian evolution such as the shift from terrestrial to an aquatic lifestyle. On the other hand, Eocene Southern Hemisphere records are significant in documenting the other critical episode in cetacean evolution: the radiation of fully aquatic whales (i.e. Pelagiceti). Pelagiceti, spread into temperate latitudes far from the Tethys Sea, and include the Basilosauridae and Neoceti the group comprising the modern lineages Mysticeti and Odontoceti. The most significant Pelagiceti records from the Southern Hemisphere were recovered from Eocene beds of the La Meseta Formation (Marambio = Seymour Island, Antarctica), and consists in fragmentary basilosaurid materials and a single specimen of the earliest member of Mysticeti, the holotype of Llanocetus denticrenatus.Fil: Buono, Mónica Romina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Nacional Patagónico; ArgentinaFil: Fernández, Marta Susana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. División Paleontología Vertebrados; ArgentinaFil: Bona, Paula. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. División Paleontología Vertebrados; ArgentinaFil: Santillana, Sergio Nestor. Ministerio de Relaciones Exteriores, Comercio Interno y Culto. Dirección Nacional del Antártico. Instituto Antártico Argentino; ArgentinaFil: Arnaudo, Eugenia. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. División Paleontología Vertebrados; ArgentinaFil: Puerta, Pablo. Museo Paleontológico Egidio Feruglio; ArgentinaFil: Reguero, Marcelo Alfredo. Ministerio de Relaciones Exteriores, Comercio Interno y Culto. Dirección Nacional del Antártico. Instituto Antártico Argentino; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaXXXIV SCAR - Open Science Conference 2016. Antarctica in the Global Earth System: from the Poles to the tropicsKuala LumpurMalasiaScientific Committee on Antarctic ResearchMinistry of Science, Technology and Innovation of Malaysi

La restricción externa en la Argentina actual: dependencia y perspectivas

XX Encontro Nacional de Economia Política: desenvolvimento Latino-Americano, Integração e Inserção Internacional - UNILA, Foz do Iguaçu, 26 a 29 de maio de 2015La reaparición de la restricción externa en la Argentina actual estar expresando mucho más que la escasez de divisas. Los problemas estructurales de la economía argentina para emprender procesos de desarrollo económico y la necesidad de equilibrar la balanza de pagos mediante la búsqueda de fi nanciamiento externo deben ponerse en perspectiva observando cómo se integra la economía argentina en la nueva confi guración del Sistema-Mundo. Este artículo se propone revisar el desarrollo periférico argentina y, en ese marco, aproximarnos a las causas que han generado la reemergencia de la Restricción Externa en Argentina desde hace pocos años. Para dar cuenta de esta dinámica, en este trabajo propondremos un marco teórico basado en los abordajes que fueron claves en la literatura latinoamericana del siglo XX para interpretar los fenómenos recientes, para luego tomar nota de las problemáticas estructurales y coyunturales que afectan al sector externo argentino actualmente. Posteriormente, estudiaremos con cierto detalle la fuga de capitales, el endeudamiento externo y las transformaciones en el sector agroalimentario, como condicionantes centrales de la restricción externa y por último, ensayaremos algunas perspectivas para pensar los futuros escenarios para el paísBanco Nacional de Desenvolvimento Econômico e Social (BNDES); Usina Hidrelétrica de Itaipu (ITAIPU); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) e Universidade Federal da Integração Latino-Americana (UNILA

Occurrence and identification of yeasts in dogs external ear canal with and without otitis

ABSTRACT Objective. To analyze the presence of yeast in the external ear canal of 116 dogs with and without a diagnosis of otitis from veterinary clinic in the Chapecó city, Santa Catarina, Brazil, and to examine the secretion of the proteinase in isolates. Materials and methods. Were collected cerumen of conduct hearing of dogs of 16 different races 71% with pendular ear type, 5% of semi-pendular and 24% of the erect type. All dogs were previously evaluated by otoscopy and grouped in dogs with and without otitis. Results. Yeasts were isolated in 44 samples (approximately 36%), where Malassezia pachydermatis was identified in 95% of samples where were observed growth of yeasts. On 20 samples the proteinase enzyme showed strong activity in 31% isolates, were 21% of the dogs with otitis tested showed high proteolytic activity. Conclusions. We observed a variation of strains of M. pachydermatis-producing enzymes. The variation in production of these enzymes is probably more associated with different response to the action of the immune system of the animal in the tissue injury