МЕТОДЫ ОЦЕНКИ УЩЕРБОВ В ЗАДАЧАХ КОЛИЧЕСТВЕННОГО АНАЛИЗА ЖИВУЧЕСТИ КРИТИЧЕСКИ ВАЖНЫХ ОБЪЕКТОВ ИНФОРМАТИЗАЦИИ

Methods of the quantitative analysis tasks of critical informatization objects survivability which are based on an assessment of damages at influence of destabilizing factors are considered. The interrelation of material, functional and structural damages is shown. The assessment of functional damage of KIOI is offered to be carried out on the basis of a method of the analysis of casual structures (systems) on productivity.Рассмотрены методы количественного анализа живучести критически важных объектов информатизации, базирующиеся на оценке ущербов при воздействии дестабилизирующих факторов. Показана взаимосвязь материального, функционального и структурного ущербов. Предложено осуществлять оценку функционального ущерба КВОИ на основе метода анализа случайных структур (систем) по производительности

Efficiency Assessment of Using Flammable Compounds from Water Treatment and Methanol Production Waste for Plasma Synthesis of Iron-Containing Pigments

This article describes the possibility of applying the low-temperature plasma for obtaining iron-containing pigments from water purification and flammable methanol production waste. In this paper were calculated combustion parameters of water-saltorganic compositions (WSOC) with different consists. Authors determined the modes of energy- efficient processing of the previously mentioned waste in an air plasma. Having considered the obtained results there were carried out experiments with flammable dispersed water-saltorganic compositions on laboratory plasma stand. All the experimental results are confirmed by calculations

АНАЛИТИЧЕСКАЯ ОЦЕНКА ЖИВУЧЕСТИ КРИТИЧЕСКИ ВАЖНОГО ОБЪЕКТА ИНФОРМАТИЗАЦИИ

The use of a method of joining the random structures (systems) on the productivity for the analytical estimation of the vitality of critically important object is examined. It’re given mathematical expressions for enumerating the productivity of object and its elements the determination of the statistical characteristics of the functions of the random arguments within the framework of the classical probability theory. It’s shown that the major advantages of the utilized method, which being somewhat bulky for the object, their consisting small number of elements, practically is not complicated with their unlimited growth and increase in the dimensionality of system.Рассмотрено использование метода сопряжения случайных структур (систем) по производительности для аналитической оценки живучести критически важного объекта. Приведены математические выражения для вычисления производительности объекта и его элементов определением статистических характеристик функций случайных аргументов в рамках классической теории вероятности. Показаны основные преимущества используемого метода, который, являясь несколько громоздким для объекта, состоящего их небольшого числа элементов, практически не усложняется при неограниченном их возрастании и увеличении размерности системы

Electrospun polyurethane/hydroxyapatite bioactive Scaffolds for bone tissue engineering: The role of solvent and hydroxyapatite particles

Abstract Polyurethane (PU) is a promising polymer to support bone–matrix producing cells due to its durability and mechanical resistance. In this study two types of medical grade poly-ether urethanes Z3A1 and Z9A1 and PU-Hydroxyapatite (PU–HA) composites were investigated for their ability to act as a scaffold for tissue engineered bone. PU dissolved in varying concentrations of dimethylformamide (DMF) and tetrahydrofuran (THF) solvents were electrospun to attain scaffolds with randomly orientated non-woven fibres. Bioactive polymeric composite scaffolds were created using 15 wt% Z3A1 in a 70/30 DMF/THF PU solution and incorporating micro- or nano-sized HA particles in a ratio of 3:1 respectively, whilst a 25 wt% Z9A1 PU solution was doped in ratio of 5:1. Chemical properties of the resulting composites were evaluated by FTIR and physical properties by SEM. Tensile mechanical testing was carried out on all electrospun scaffolds. MLO-A5 osteoblastic mouse cells and human embryonic mesenchymal progenitor cells, hES-MPs were seeded on the scaffolds to test their biocompatibility and ability to support mineralised matrix production over a 28 day culture period. Cell viability was assayed by MTT and calcium and collagen deposition by Sirius red and alizarin red respectively. SEM images of both electrospun PU scaffolds and PU–HA composite scaffolds showed differences in fibre morphology with changes in solvent combinations and size of HA particles. Inclusion of THF eliminated the presence of beads in fibres that were present in scaffolds fabricated with 100% DMF solvent, and resulted in fibres with a more uniform morphology and thicker diameters. Mechanical testing demonstrated that the Young׳s Modulus and yield strength was lower at higher THF concentrations. Inclusion of both sizes of HA particles in PU–HA solutions reinforced the scaffolds leading to higher mechanical properties, whilst FTIR characterisation confirmed the presence of HA in all composite scaffolds. Although all scaffolds supported proliferation of both cell types and deposition of calcified matrix, PU–HA composite fibres containing nano-HA enabled the highest cell viability and collagen deposition. These scaffolds have the potential to support bone matrix formation for bone tissue engineering