Investigation of cardiac functions and aortic stiffness in children with type 1 diabetes mellitus: A prospective study

Objective: Cardiovascular diseases represent the most serious complications in the patients with type 1 diabetes mellitus (DM). Endothelial dysfunction and increased aortic stiffness play role in the occurance of these disorders. Aim of this study is to evaluate the patients cardiac functions and aortic elasticity parameters in children with type 1 DM. Materials and methods: Thirty nine patients with type 1 DM and 39 controls were included in the study. After physical examination, cardiac evaluation was performed with conventional echocardiography, Doppler and tissue Doppler echocardiography. Aortic elasticty parameters were calculated. Results: Systolic blood pressure, mean arterial pressure (MAP), pulse pressure (PP) and heart rate (HR) were higher in the patients than controls (p0.05, for all). Aortic systolic and diastolic diameters and aortic elasticity parameters were similar with controls (p>0.05, for all). Echocardiographic parameters and aortic elasticity parameters were similar in the patients who were grouped according to hemoglobin A1c and duration of diabetes (p>0.05, for all). E wave velocity was positively related with PP, while E’/A’ was positively associated with HR and negatively associated with MAP and diastolic blood pressure (p<0.05, for all). Conclusions: Diastolic dysfunction findings were stated in the diabetic children. Even though aortic compliance did not show impairment, periodic cardiac evaluation should be performed in case of progression. Patients with type 1 diabetes should be monitored for endothelial dysfunction and aortic stiffness when the prolonged life expectancy was taken into account for diabetic children

Mathematical Modelling of In-Chamber Processes in Hydrocombined Propellant Solid Rocket Motors

The special conditions of employment of commercial rockets in the sea environment has opened up new possibilities of improving motor performance. The interesting method suggests supplying water into the running motor. This paper reports the calculations and experiments carried out with solid propellant model setups. The results prove the validity of the proposed method and allow the refinement of calculation techniques for the prediction of solid rocket motor performance characteristics. The serviceability of the solid propellant charges working in combination with water is demonstrated. A mathematical model is proposed for the operation of a hydrocombined propellant motor with water and powdered additives applied to the combustion chamber.

Clinical and Laboratory Characteristics of Hyperprolactinemia in Children and Adolescents: National Survey

Conclusion: We present the largest cohort of children and adolescents with hyperprolactinemia in the literature to date. Hyperprolactinemia is more common in females and cabergoline is highly effective and practical to use in adolescents, due to its biweekly dosing. Indications for surgery in pediatric cases need to be revised

Valuation of the company nkt cables Vrchlabí k.s., member of the NKT Group

Cílem této diplomové práce je stanovení hodnoty podniku nkt cables Vrchlabí k.s., člen skupiny NKT, zhodnocení jeho finanční situaci z různých hledisek a objektivní posouzení perspektivy podniku k datu ocenění 1. května 2013. Práce se skládá ze dvou části. První část se zabývá teoretickou problematikou ocenění podniku. Teoretická část se skládá z prvních devíti kapitol této diplomové práce, které se věnují teoretické problematice ocenění podniku. Praktická část je věnována ocenění konkrétního podniku. Je provedená strategická analýza, která je nezbytná pro prognózování budoucího vývoje podniku. Následně je uvedena finanční analýza, která ukazuje jak na silné stránky podniku, tak i na existenci určitých problémů. V závěrečné části je sestaven finanční plán společnosti a vypočtena hodnota podniku k 1.5.2013 s použitím metody diskontovaného cash flow ve variantě pro věřitele a vlastníky.The main aim of this thesis is to determine the value of the company nkt cables Vrchlabí k.s., member of the NKT Group. The thesis consists of two parts. The first part deals with theoretical issues of company valuation, describes the definition of value and explains the basic principles of its calculating. The practical part is devoted to the valuation of a particular company. It was made strategic analysis and financial analysis that show the strengths of the company, as well as the existence of certain problems. In the final part of the thesis is drawn a financial plan and calculated value of the company with help of discounted cash flow method for creditors and owners

Ekonomická analýza podniku Kablo Elektro, a.s.

Za cíl mé práce jsem stanovil zhodnotit ekonomickou situaci a finanční zdraví největší české kabelářské společnosti Kablo Elektro a.s. pomocí ekonomické analýzy v letech 2001?2006. V první části práce se budu stručně věnovat ekonomické analýze obecně. V teoretické části popíši metodologii pro výpočet ukazatelů ekonomické analýzy. V aplikační části práce se pak na základě podkladů z finančního účetnictví budu snažit o analýzu a interpretaci těchto výkazů podniku, a dále o zhodnocení jeho finanční pozice. Auditované účetní uzávěrky jsou dostupné zatím jen do roku 2006. Proto o činnosti podniku v roce 2007 se budu věnovat jen popisně. V závěru své práce se pokusím shrnout všechny výsledky a najít některé příčiny stávající situace

Temporary Tax Aplication in the Turkish Tax System

Geçici vergi, kazanç vergileri ile ilgili olarak (kesin tahakkuk ve tahsil işlemleri sonradan gerçekleşen) henüz vergileme dönemi sona ermeden, bir mahsup sistemi çerçevesinde tahsilini öne alan bir uygulamadır. Üzerinde çok araştırma gerektirecek “Geçici Vergi Uygulaması”, bu çalışmada üç bölümden oluşmaktadır. Birinci bölümde geçici verginin tanımı yapılarak, geçici verginin soy ağacı çıkarılmaya çalışılmıştır. Ayrıca geçici vergi ile ilgili kanuni düzenlemeler irdelenerek daha çok geçici vergi uygulamasının kapsamı üzerinde durulmuştur. İkinci bölümde, geçici verginin mükellefleri üzerinde durularak geçici vergiye tabi kazançlar tespit edilmeye çalışılmıştır. Ayrıca geçici vergi dönemleri baz alınarak uygulamalı bir örnekle konu pekiştirilmeye çalışılmıştır. Son bölümde ise geçici vergiye ilişkin ortaya çıkan tartışmalara yer verilerek, oluşan sorunlara çözüm aranmıştır.Temporary tax, in relation to the profit tax (accurate assessment and collection processes that occur later), yet before the end of the period of taxation, the tax collection under a tax deduction system appears to be an application field forward. "Temporary Tax Practice" to require a lot of research on in this study consists of three parts. In the first part, being done definition of temporary tax, family tree of temporary tax is tried to be form. Also examining the legal arrangements related to temporary tax, it is focused more on the scope of application of temporary tax. In the second part, emphasis will be on a temporary provisional tax payers ,it is tried to determine taxable profits. In addition,with a practical example on the basis of temporary tax periods, subject is tried to be intensified. In the last section, given period of time in the debate on the temporary tax , problems consisting are sought solutions

Temporary Tax Aplication in the Turkish Tax System

Geçici vergi, kazanç vergileri ile ilgili olarak (kesin tahakkuk ve tahsil işlemleri sonradan gerçekleşen) henüz vergileme dönemi sona ermeden, bir mahsup sistemi çerçevesinde tahsilini öne alan bir uygulamadır. Üzerinde çok araştırma gerektirecek “Geçici Vergi Uygulaması”, bu çalışmada üç bölümden oluşmaktadır. Birinci bölümde geçici verginin tanımı yapılarak, geçici verginin soy ağacı çıkarılmaya çalışılmıştır. Ayrıca geçici vergi ile ilgili kanuni düzenlemeler irdelenerek daha çok geçici vergi uygulamasının kapsamı üzerinde durulmuştur. İkinci bölümde, geçici verginin mükellefleri üzerinde durularak geçici vergiye tabi kazançlar tespit edilmeye çalışılmıştır. Ayrıca geçici vergi dönemleri baz alınarak uygulamalı bir örnekle konu pekiştirilmeye çalışılmıştır. Son bölümde ise geçici vergiye ilişkin ortaya çıkan tartışmalara yer verilerek, oluşan sorunlara çözüm aranmıştır.Temporary tax, in relation to the profit tax (accurate assessment and collection processes that occur later), yet before the end of the period of taxation, the tax collection under a tax deduction system appears to be an application field forward. "Temporary Tax Practice" to require a lot of research on in this study consists of three parts. In the first part, being done definition of temporary tax, family tree of temporary tax is tried to be form. Also examining the legal arrangements related to temporary tax, it is focused more on the scope of application of temporary tax. In the second part, emphasis will be on a temporary provisional tax payers ,it is tried to determine taxable profits. In addition,with a practical example on the basis of temporary tax periods, subject is tried to be intensified. In the last section, given period of time in the debate on the temporary tax , problems consisting are sought solutions