Coexistence of dilute and densely packed domains of ligand-receptor bonds in membrane adhesion

We analyze the stability of micro-domains of ligand-receptor bonds that mediate the adhesion of biological model membranes. After evaluating the effects of membrane fluctuations on the binding affinity of a single bond, we characterize the organization of bonds within the domains by theoretical means. In a large range of parameters, we find the commonly suggested dense packing to be separated by a free energy barrier from a regime in which bonds are sparsely distributed. If bonds are mobile, a coexistence of the two regimes should emerge, which agrees with recent experimental observations.Comment: 6 pages, 6 figures, accepted by EP

Fragmentation and dynamical collapse of the starless high-mass star-forming region IRDC18310-4

Aims: We study the fragmentation and dynamical properties of a massive starless gas clump at the onset of high-mass star formation. Methods: Based on Herschel continuum data we identify a massive gas clump that remains far-infrared dark up to 100mum wavelengths. The fragmentation and dynamical properties are investigated by means of Plateau de Bure Interferometer and Nobeyama 45m single-dish spectral line and continuum observations. Results: The massive gas reservoir fragments at spatial scales of ~18000AU in four cores. Comparing the spatial extent of this high-mass region with intermediate- to low-mass starless cores from the literature, we find that linear sizes do not vary significantly over the whole mass regime. However, the high-mass regions squeeze much more gas into these similar volumes and hence have orders of magnitude larger densities. The fragmentation properties of the presented low-to high-mass regions are consistent with gravitational instable Jeans fragmentation. Furthermore, we find multiple velocity components associated with the resolved cores. Recent radiative transfer hydrodynamic simulations of the dynamic collapse of massive gas clumps also result in multiple velocity components along the line of sight because of the clumpy structure of the regions. This result is supported by a ratio between viral and total gas mass for the whole region <1. Conclusions: This apparently still starless high-mass gas clump exhibits clear signatures of early fragmentation and dynamic collapse prior to the formation of an embedded heating source. A comparison with regions of lower mass reveals that the linear size of star-forming regions does not necessarily have to vary much for different masses, however, the mass reservoirs and gas densities are orders of magnitude enhanced for high-mass regions compared to their lower-mass siblings.Comment: 11 pages, 10 figures, accepted to Astronomy and Astrophysics, high-resolution version with all figures included can be found at http://www.mpia.de/homes/beuther/papers.htm

A search for hypercompact HII regions in the Galactic Plane

22 pages, 8 figures, 6 tables, accepted by MNRASWe have carried out the largest and most unbiased search for hypercompact (HC) H II regions. Our method combines four interferometric radio continuum surveys (THOR, CORNISH, MAGPIS, and White2005) with far-infrared and sub-mm Galactic Plane surveys to identify embedded H II regions with positive spectral indices; 120 positive spectrum H II regions have been identified from a total sample of 534 positive spectral index radio sources. None of these H II regions, including the known HC H II regions recovered in our search, fulfills the canonical definition of an HC H II region at 5 GHz. We suggest that the current canonical definition of HC H II regions is not accurate and should be revised to include a hierarchical structure of ionized gas that results in an extended morphology at 5 GHz. Correlating our search with known ultracompact (UC) H II region surveys, we find that roughly half of detected UC H II regions have positive spectral indices, instead of more commonly assumed flat and optically thin spectra. This implies a mix of optically thin and thick emission and has important implications for previous analyses which have so far assumed optically thin emission for these objects. Positive spectrum H II regions are statistically more luminous and possess higher Lyman continuum fluxes than H II regions with flat or negative indices. Positive spectrum H II regions are thus more likely to be associated with more luminous and massive stars. No differences are found in clump mass, linear diameter, or luminosity-to-mass ratio between positive spectrum and non-positive spectrum H II regions.Peer reviewedFinal Accepted Versio

CHIMPS: the ¹³CO/C¹⁸O (<i>J</i> = 3 → 2) Heterodyne Inner Milky Way Plane Survey

We present the 13CO/C18O (J = 3 → 2) Heterodyne Inner Milky Way Plane Survey (CHIMPS) which has been carried out using the Heterodyne Array Receiver Program on the 15 m James Clerk Maxwell Telescope (JCMT) in Hawaii. The high-resolution spectral survey currently covers |b| ≤ 0.5° and 28° ≲ l ≲ 46°, with an angular resolution of 15 arcsec in 0.5 km s-1 velocity channels. The spectra have a median rms of ˜0.6 K at this resolution, and for optically thin gas at an excitation temperature of 10 K, this sensitivity corresponds to column densities of NH2 ˜ 3 × 1020 cm-2 and NH2 ˜ 4 × 1021 cm-2 for 13CO and C18O, respectively. The molecular gas that CHIMPS traces is at higher column densities and is also more optically thin than in other publicly available CO surveys due to its rarer isotopologues, and thus more representative of the three-dimensional structure of the clouds. The critical density of the J = 3 → 2 transition of CO is ≳104 cm-3 at temperatures of ≤20 K, and so the higher density gas associated with star formation is well traced. These data complement other existing Galactic plane surveys, especially the JCMT Galactic Plane Survey which has similar spatial resolution and column density sensitivity, and the Herschel infrared Galactic Plane Survey. In this paper, we discuss the observations, data reduction and characteristics of the survey, presenting integrated-emission maps for the region covered. Position-velocity diagrams allow comparison with Galactic structure models of the Milky Way, and while we find good agreement with a particular four-arm model, there are some significant deviations

A survey for hydroxyl in the THOR pilot region around W43

We report on observations of the hydroxyl radical (OH) within The Hι, OH, Recombination line survey (THOR) pilot region. The region is bounded approximately between Galactic coordinates l = 29 .2 to 31 .5 and b = −1 .0 to +1 .0 and includes the high-mass star-forming region W43. We identify 103 maser sites, including 72 with 1612 MHz masers, 42 showing masers in either of the main-line transitions at 1665 and 1667 MHz and four showing 1720 MHz masers. Most maser sites with either main-line or 1720 MHz emission are associated with star formation, whereas most of the 1612 MHz masers are associated with evolved stars. We find that nearly all of the main-line maser sites are co-spatial with an infrared source, detected by GLIMPSE. We also find diffuse OH emission, as well as OH in absorption towards selected unresolved or partially resolved sites. Extended OH absorption is found towards the well-known star-forming complex W43 Main

Radio continuum emission in the northern Galactic plane: Sources and spectral indices from the THOR survey

Radio continuum surveys of the Galactic plane can find and characterize HII regions, supernova remnants (SNRs), planetary nebulae (PNe), and extragalactic sources. A number of surveys at high angular resolution (<25") at different wavelengths exist to study the interstellar medium (ISM), but no comparable high-resolution and high-sensitivity survey exists at long radio wavelengths around 21cm. We observed a large fraction of the Galactic plane in the first quadrant of the Milky Way (l=14.0-67.4deg and |b| < 1.25deg) with the Karl G. Jansky Very Large Array (VLA) in the C-configuration covering six continuum spectral windows. These data provide a detailed view on the compact as well as extended radio emission of our Galaxy and thousands of extragalactic background sources. We used the BLOBCAT software and extracted 10916 sources. After removing spurious source detections caused by the sidelobes of the synthesised beam, we classified 10387 sources as reliable detections. We smoothed the images to a common resolution of 25" and extracted the peak flux density of each source in each spectral window (SPW) to determine the spectral indices $\alpha$ (assuming $I(\nu)\propto\nu^\alpha$). By cross-matching with catalogs of HII regions, SNRs, PNe, and pulsars, we found radio counterparts for 840 HII regions, 52 SNRs, 164 PNe, and 38 pulsars. We found 79 continuum sources that are associated with X-ray sources. We identified 699 ultra-steep spectral sources ($\alpha < -1.3$) that could be high-redshift galaxies. Around 9000 of the sources we extracted are not classified specifically, but based on their spatial and spectral distribution, a large fraction of them is likely to be extragalactic background sources. More than 7750 sources do not have counterparts in the SIMBAD database, and more than 3760 sources do not have counterparts in the NED database

A Survey for Hydroxyl in the THOR Pilot Region around W43

We report on observations of the hydroxyl radical (OH) within The H{\sc I}, OH Recombination line survey (THOR) pilot region. The region is bounded approximately between Galactic coordinates l=29.2 to 31.5$^\circ$ and b=-1.0 to +1.0$^\circ$ and includes the high-mass star forming region W43. We identify 103 maser sites, including 72 with 1612\,MHz masers, 42 showing masers in either of the main line transitions at 1665 and 1667\,MHz and four showing 1720\,MHz masers. Most maser sites with either main-line or 1720\,MHz emission are associated with star formation, whereas most of the 1612\,MHz masers are associated with evolved stars. We find that nearly all of the main-line maser sites are co-spatial with an infrared source, detected by GLIMPSE. We also find diffuse OH emission, as well as OH in absorption towards selected unresolved or partially resolved sites. Extended OH absorption is found towards the well known star forming complex W43 Main

OH absorption in the first quadrant of the Milky Way as seen by THOR

The hydroxyl radical (OH) is present in the diffuse molecular and partially atomic phases of the interstellar medium (ISM), but its abundance relative to hydrogen is not clear. We aim to evaluate the abundance of OH with respect to molecular hydrogen using OH absorption against cm-continuum sources over the first Galactic quadrant. This OH study is part of the HI/OH/Recombination line survey (THOR). THOR is a Karl G. Jansky Very Large Array large program of atomic, molecular and ionized gas in the range 15{\deg}$\leq$l$\leq$67{\deg} and |b|$\leq$1{\deg}. It is the highest-resolution unbiased OH absorption survey to date towards this region. We combine the derived optical depths with literature 13CO(1-0) and HI observations to determine the OH abundance. We detect absorption in the 1665 and 1667 MHz transitions for continuum sources stronger than $F_{\rm cont}\geq$0.1 Jy/beam. OH absorption is found against $\sim$15% of these continuum sources with increasing fractions for stronger sources. Most of the absorption is associated with Galactic HII regions. We find OH and 13CO gas to have similar kinematic properties. The OH abundance decreases with increasing hydrogen column density. The OH abundance with respect to the total hydrogen nuclei column density (atomic and molecular phase) is in agreement with a constant abundance for $A_V$ < 10-20. Towards the lowest column densities, we find sources that exhibit OH absorption but no 13CO emission, indicating that OH is a well suited tracer of the low column density molecular gas. We present spatially resolved OH absorption towards W43. The unbiased nature of the THOR survey opens a new window onto the gas properties of the ISM. The characterization of the OH abundance over a large range of hydrogen gas column densities contributes to the understanding of OH as a molecular gas tracer and provides a starting point for future investigations

Continuum sources from the THOR survey between 1 and 2 GHz

We carried out a large program with the Karl G. Jansky Very Large Array (VLA): "THOR: The HI, OH, Recombination line survey of the Milky Way". We observed a significant portion of the Galactic plane in the first quadrant of the Milky Way in the 21cm HI line, 4 OH transitions, 19 radio recombination lines, and continuum from 1 to 2 GHz. In this paper we present a catalog of the continuum sources in the first half of the survey (l=14.0-37.9deg and l=47.1-51.2deg, |b|<1.1deg) at a spatial resolution of 10-25", with a spatially varying noise level of ~0.3-1 mJy/beam. The catalog contains ~4400 sources. Around 1200 of these are spatially resolved, and ~1000 are possible artifacts, given their low signal-to-noise ratios. Since the spatial distribution of the unresolved objects is evenly distributed and not confined to the Galactic plane, most of them are extragalactic. Thanks to the broad bandwidth of the observations from 1 to 2 GHz, we are able to determine a reliable spectral index for ~1800 sources. The spectral index distribution reveals a double-peaked profile with maxima at spectral indices of alpha = -1 and alpha = 0 , corresponding to steep declining and flat spectra, respectively. This allows us to distinguish between thermal and non-thermal emission, which can be used to determine the nature of each source. We examine the spectral index of ~300 known HII regions, for which we find thermal emission with spectral indices around alpha = 0. In contrast, supernova remnants (SNR) show non-thermal emission with alpha = -0.5 and extragalactic objects generally have a steeper spectral index of alpha = -1. Using the spectral index information of the THOR survey, we investigate potential SNR candidates. We classify the radiation of four SNR candidates as non-thermal, and for the first time, we provide strong evidence for the SNR origin of these candidates