Contact stress analysis of spiral bevel gears using nonlinear finite element static analysis

A procedure is presented for performing three-dimensional stress analysis of spiral bevel gears in mesh using the finite element method. The procedure involves generating a finite element model by solving equations that identify tooth surface coordinates. Coordinate transformations are used to orientate the gear and pinion for gear meshing. Contact boundary conditions are simulated with gap elements. A solution technique for correct orientation of the gap elements is given. Example models and results are presented

Coherent light transport in a cold Strontium cloud

We study light coherent transport in the weak localization regime using magneto-optically cooled strontium atoms. The coherent backscattering cone is measured in the four polarization channels using light resonant with a J=0 to J=1 transition of the Strontium atom. We find an enhancement factor close to 2 in the helicity preserving channel, in agreement with theoretical predictions. This observation confirms the effect of internal structure as the key mechanism for the contrast reduction observed with an Rubidium cold cloud (see: Labeyrie et al., PRL 83, 5266 (1999)). Experimental results are in good agreement with Monte-Carlo simulations taking into account geometry effects.Comment: 4 pages, 2 figure

Manual for automatic generation of finite element models of spiral bevel gears in mesh

The goal of this research is to develop computer programs that generate finite element models suitable for doing 3D contact analysis of faced milled spiral bevel gears in mesh. A pinion tooth and a gear tooth are created and put in mesh. There are two programs: Points.f and Pat.f to perform the analysis. Points.f is based on the equation of meshing for spiral bevel gears. It uses machine tool settings to solve for an N x M mesh of points on the four surfaces, pinion concave and convex, and gear concave and convex. Points.f creates the file POINTS.OUT, an ASCI file containing N x M points for each surface. (N is the number of node points along the length of the tooth, and M is nodes along the height.) Pat.f reads POINTS.OUT and creates the file tl.out. Tl.out is a series of PATRAN input commands. In addition to the mesh density on the tooth face, additional user specified variables are the number of finite elements through the thickness, and the number of finite elements along the tooth full fillet. A full fillet is assumed to exist for both the pinion and gear

Contact Stress Analysis of Spiral Bevel Gears Using Finite Element Analysis

A procedure is presented for performing three-dimensional stress analysis of spiral bevel gears in mesh using the finite element method. The procedure involves generating a finite element model by solving equations that identify tooth surface coordinates. Coordinate transformations are used to orientate the gear and pinion for gear meshing. Contact boundary conditions are simulated with gap elements. A solution technique for correct orientation of the gap elements is given. Example models and results are presented

Comparison of Gap Elements and Contact Algorithm for 3D Contact Analysis of Spiral Bevel Gears

Three dimensional stress analysis of spiral bevel gears in mesh using the finite element method is presented. A finite element model is generated by solving equations that identify tooth surface coordinates. Contact is simulated by the automatic generation of nonpenetration constraints. This method is compared to a finite element contact analysis conducted with gap elements

Middle-out reasoning for synthesis and induction

We develop two applications of middle-out reasoning in inductive proofs: Logic program synthesis and the selection of induction schemes. Middle-out reasoning as part of proof planning was first suggested by Bundy et al [Bundy et al 90a]. Middle-out reasoning uses variables to represent unknown terms and formulae. Unification instantiates the variables in the subsequent planning, while proof planning provides the necessary search control. Middle-out reasoning is used for synthesis by planning the verification of an unknown logic program: The program body is represented with a meta-variable. The planning results both in an instantiation of the program body and a plan for the verification of that program. If the plan executes successfully, the synthesized program is partially correct and complete. Middle-out reasoning is also used to select induction schemes. Finding an appropriate induction scheme during synthesis is difficult, because the recursion of the program, which is un..

Novel lines of Pax6-/- embryonic stem cells exhibit reduced neurogenic capacity without loss of viability

<p>Abstract</p> <p>Background</p> <p>Embryonic stem (ES) cells can differentiate into all cell types and have been used extensively to study factors affecting neuronal differentiation. ES cells containing mutations in known genes have the potential to provide useful in vitro models for the study of gene function during neuronal differentiation. Recently, mouse ES cell lines lacking the neurogenic transcription factor Pax6 were reported; neurons derived from these <it>Pax6</it>^-/-ES cells died rapidly after neuronal differentiation in vitro.</p> <p>Results</p> <p>Here we report the derivation of new lines of <it>Pax6</it>^-/-ES cells and the assessment of their ability to survive and differentiate both in vitro and in vivo. Neurons derived from our new <it>Pax6</it>^-/-lines were viable and continued to elaborate processes in culture under conditions that resulted in the death of neurons derived from previously reported <it>Pax6</it>^-/-ES cell lines. The new lines of <it>Pax6</it>^-/-ES cells showed reduced neurogenic potential, mimicking the effects of loss of Pax6 in vivo. We used our new lines to generate <it>Pax6</it>^-/-↔ <it>Pax6</it>^+/+chimeras in which the mutant cells survived and displayed the same phenotypes as <it>Pax6</it>^-/-cells in <it>Pax6</it>^-/-↔ <it>Pax6</it>^+/+chimeras made by embryo aggregation.</p> <p>Conclusions</p> <p>We suggest that loss of Pax6 from ES cells reduces their neurogenic capacity but does not necessarily result in the death of derived neurons. We offer these new lines as additional tools for those interested in the generation of chimeras and the analysis of in vitro ES cell models of Pax6 function during neuronal differentiation, embryonic and postnatal development.</p

Prolog Technology Reinforcement Learning Prover: (System Description)

We present a reinforcement learning toolkit for experiments with guiding automated theorem proving in the connection calculus. The core of the toolkit is a compact and easy to extend Prolog-based automated theorem prover called plCoP. plCoP builds on the leanCoP Prolog implementation and adds learning-guided Monte-Carlo Tree Search as done in the rlCoP system. Other components include a Python interface to plCoP and machine learners, and an external proof checker that verifies the validity of plCoP proofs. The toolkit is evaluated on two benchmarks and we demonstrate its extendability by two additions: (1) guidance is extended to reduction steps and (2) the standard leanCoP calculus is extended with rewrite steps and their learned guidance. We argue that the Prolog setting is suitable for combining statistical and symbolic learning methods. The complete toolkit is publicly released. © 2020, Springer Nature Switzerland AG

Genomic Prevalence of Heterochromatic H3K9me2 and Transcription Do Not Discriminate Pluripotent from Terminally Differentiated Cells

Cellular differentiation entails reprogramming of the transcriptome from a pluripotent to a unipotent fate. This process was suggested to coincide with a global increase of repressive heterochromatin, which results in a reduction of transcriptional plasticity and potential. Here we report the dynamics of the transcriptome and an abundant heterochromatic histone modification, dimethylation of histone H3 at lysine 9 (H3K9me2), during neuronal differentiation of embryonic stem cells. In contrast to the prevailing model, we find H3K9me2 to occupy over 50% of chromosomal regions already in stem cells. Marked are most genomic regions that are devoid of transcription and a subgroup of histone modifications. Importantly, no global increase occurs during differentiation, but discrete local changes of H3K9me2 particularly at genic regions can be detected. Mirroring the cell fate change, many genes show altered expression upon differentiation. Quantitative sequencing of transcripts demonstrates however that the total number of active genes is equal between stem cells and several tested differentiated cell types. Together, these findings reveal high prevalence of a heterochromatic mark in stem cells and challenge the model of low abundance of epigenetic repression and resulting global basal level transcription in stem cells. This suggests that cellular differentiation entails local rather than global changes in epigenetic repression and transcriptional activity